[SCHEDULE 13G/A] SCYNEXIS INC SEC Filing

Rhea-AI Filing Summary

Federated Hermes, Inc. and related Reporting Persons report beneficial ownership of 5,116,598 shares of Scynexis Inc. common stock, representing 11.26% of the outstanding shares as of the event date 09/30/2025. The filing is an Amendment to Schedule 13G and lists ownership held by Federated Hermes, Inc., Voting Shares Irrevocable Trust, and three individual reporting persons who share voting and dispositive power over the same block. The filing states the securities were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing control. Signatures for the filing and trust acknowledgments are dated 10/07/2025, with exhibits noted for subsidiary classification, a joint filing agreement, and a power of attorney.

Positive

• Material institutional ownership: Federated Hermes holds 5,116,598 shares representing 11.26%, which can provide investor oversight and stewardship
• Clean intent statement: The filing explicitly states holdings were acquired in the ordinary course and not to change or influence control

Negative

• None.

Insights

Institutional Ownership Analyst

An institutional holder reports an 11.26% stake, a material ownership level for investors.

The filing shows Federated Hermes, Inc. and the Voting Shares Irrevocable Trust collectively hold 5,116,598 shares, equal to 11.26% of the class. Ownership is reported with sole voting and dispositive power by Federated Hermes and shared voting/dispositive power by individual trustees, indicating centralized control over the block.

The statement that shares are held in the ordinary course of business and not for control purposes reduces governance-change signaling, but the >5% position remains material to shareholders. Watch for any follow-up amendments, changes in percentage, or schedule filings that would indicate active engagement or additional accumulation within the next few reporting periods.

Corporate Governance Specialist

A single institutional holder plus an associated trust holding >10% can influence governance outcomes indirectly.

The report lists voting arrangements where Federated Hermes reports sole voting and dispositive power while related individuals report shared powers over the same 5,116,598 shares. This structure is commonly used to centralize stewardship decisions while fulfilling reporting rules.

Because the filing explicitly disclaims intent to change control, immediate governance action is not claimed. Investors should monitor proxy season filings and any investor communications for potential voting recommendations or nominee activity over the next 6–12 months.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 15)

SCYNEXIS INC

(Name of Issuer)

COMMON STOCK

(Title of Class of Securities)

811292200

(CUSIP Number)

09/30/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. 811292200

1

Names of Reporting Persons

Federated Hermes, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

PENNSYLVANIA

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 5,116,598.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 5,116,598.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

5,116,598.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

11.26 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

CUSIP No. 811292200

1

Names of Reporting Persons

Voting Shares Irrevocable Trust

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

PENNSYLVANIA

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 5,116,598.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 5,116,598.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

5,116,598.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

11.26 %

12

Type of Reporting Person (See Instructions)

OO

SCHEDULE 13G

CUSIP No. 811292200

1

Names of Reporting Persons

Thomas R. Donahue

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 5,116,598.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 5,116,598.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

5,116,598.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

11.26 %

12

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13G

CUSIP No. 811292200

1

Names of Reporting Persons

Ann C. Donahue

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 5,116,598.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 5,116,598.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

5,116,598.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

11.26 %

12

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13G

CUSIP No. 811292200

1

Names of Reporting Persons

J. Christopher Donahue

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 5,116,598.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 5,116,598.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

5,116,598.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

11.26 %

12

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13G

Item 1.
(a)	Name of issuer: SCYNEXIS INC
(b)	Address of issuer's principal executive offices: 1 Evertrust Plaza, 13th Floor, Jersey City, NJ 07302-6548
Item 2.
(a)	Name of person filing: Federated Hermes, Inc.
(b)	Address or principal business office or, if none, residence: 1001 Liberty Avenue, Pittsburgh, PA 15222-3779
(c)	Citizenship: Pennsylvania
(d)	Title of class of securities: COMMON STOCK
(e)	CUSIP No.: 811292200
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 5,116,598
(b)	Percent of class: 11.26 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 5,116,598
	(ii) Shared power to vote or to direct the vote: 0
	(iii) Sole power to dispose or to direct the disposition of: 5,116,598
	(iv) Shared power to dispose or to direct the disposition of: 0
Item 5.	Ownership of 5 Percent or Less of a Class.
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. See Exhibit "1" Attached
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Federated Hermes, Inc.

Signature:	/s/J. Christopher Donahue
Name/Title:	J. Christopher Donahue, as President of Federated Hermes, Inc.
Date:	10/07/2025

Voting Shares Irrevocable Trust

Signature:	/s/Thomas R. Donahue
Name/Title:	Thomas R. Donahue, as Trustee of Voting Shares Irrevocable Trust
Date:	10/07/2025

Signature:	/s/Ann C. Donahue
Name/Title:	Ann C. Donahue, as Trustee of Voting Shares Irrevocable Trust
Date:	10/07/2025

Signature:	/s/J. Christopher Donahue
Name/Title:	J. Christopher Donahue, as Trustee of Voting Shares Irrevocable Trust
Date:	10/07/2025

Thomas R. Donahue

Signature:	/s/Thomas R. Donahue
Name/Title:	Thomas R. Donahue
Date:	10/07/2025

Ann C. Donahue

Signature:	/s/Ann C. Donahue
Name/Title:	Ann C. Donahue
Date:	10/07/2025

J. Christopher Donahue

Signature:	/s/J. Christopher Donahue
Name/Title:	J. Christopher Donahue
Date:	10/07/2025

Comments accompanying signature: SEE EXHIBITS 2 AND 3 ATTACHED Exhibit Information EXHIBIT 1 ITEM 3 CLASSIFICATION OF REPORTING PERSON EXHIBIT 2 AGREEMENT FOR JOINT FILING OF SCHEDULE 13G EXHIBIT 3 POWER OF ATTORNEY

FAQ

What stake does Federated Hermes hold in SCYNEXIS (SCYX)?

Federated Hermes, Inc. reports beneficial ownership of 5,116,598 shares, equal to 11.26% of SCYNEXIS common stock.

Does the filing state Federated Hermes intends to change control of SCYNEXIS (SCYX)?

No. The filing certifies the securities were acquired and are held in the ordinary course of business and were not acquired to change or influence control.

Who else is listed as a reporting person on the Schedule 13G/A for SCYNEXIS?

The Voting Shares Irrevocable Trust and individuals Thomas R. Donahue, Ann C. Donahue, and J. Christopher Donahue are named, each reported with the same aggregate beneficial ownership.

When was the Schedule 13G/A signature dated?

Signatures for the filing and trust acknowledgments are dated 10/07/2025 and the event date requiring the filing is 09/30/2025.

Does the filing include exhibits or supporting agreements?

Yes. Exhibits referenced include an Item 3 classification exhibit, an agreement for joint filing, and a power of attorney.