Seer CFO David Horn to resign Oct. 1, 2026

Seer, Inc. discloses the resignation of its President and CFO and appoints existing executives to key leadership and finance roles effective October 1, 2026.

Rhea-AI Filing Summary

Seer, Inc. (SEER) announced that David Horn resigned as President, Chief Financial Officer and Treasurer to pursue other interests, effective October 1, 2026. The company states his resignation is not due to any disagreement related to its operations.

Seer has offered to extend the post-termination exercise period of Mr. Horn’s vested and exercisable stock options until one year after his last day of service, subject to plan terms and his signing and not revoking a separation and release agreement. Effective October 1, 2026, the board appointed Omid Farokhzad, M.D., already Chief Executive Officer and Chair, as President, and Charles Endweiss, currently Vice President, Financial Planning & Analysis, as Treasurer, principal financial officer and principal accounting officer.

The company describes Mr. Endweiss’s background in finance and operations at technology companies and confirms he continues under existing compensation arrangements, has entered into its standard-form indemnification agreement, and has no related-party relationships or transactions requiring disclosure.

Positive

• None.

Negative

• President and CFO resignation: David Horn will step down as President, Chief Financial Officer and Treasurer effective October 1, 2026, removing a long-serving key financial and operational leader.

8-K Event Classification

Item 5.02 — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers

1 item

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers Governance

Key personnel changes including departures, elections, or appointments of directors and executive officers.

Key Figures

Effective date of resignation and appointments: October 1, 2026 Option exercise extension period: 1 year Age of new principal financial officer: 49 years

3 metrics

Effective date of resignation and appointments October 1, 2026 Date when David Horn’s resignation becomes effective and new roles for Omid Farokhzad and Charles Endweiss begin

Option exercise extension period 1 year Offered post-termination exercise period for David Horn’s vested and exercisable stock options after his last day of service

Age of new principal financial officer 49 years Age of Charles Endweiss as disclosed in the executive background description

Key Terms

principal financial officer, principal accounting officer, indemnification agreement, Item 404(a) of Regulation S-K

4 terms

principal financial officer regulatory

"will also serve as the principal financial officer and principal accounting officer"

The principal financial officer is the senior executive who runs a company's financial operations: preparing and certifying financial reports, managing accounting controls, budgets and cash flow, and advising on financial strategy. Investors care about this role because its competence affects how trustworthy the company’s numbers are, how well it manages risk and capital needs, and the credibility of forecasts—like the chief navigator steering a firm's financial course.

principal accounting officer regulatory

"will also serve as the principal financial officer and principal accounting officer"

The Principal Accounting Officer is the person responsible for making sure a company's financial records are accurate and follow the rules. They play a key role in preparing financial reports that show how well the company is doing. This helps investors, managers, and regulators trust the company's financial information.

indemnification agreement regulatory

"Mr. Endweiss entered into an indemnification agreement on the Company’s standard form"

An indemnification agreement is a contract in which one party promises to cover losses, costs, or legal claims that another party might face, acting like a tailored safety net or private insurance policy. For investors, it matters because such agreements shift potential financial risk away from a company or its officers and onto the indemnifier, which can affect a company’s future liabilities, cash flow and how risky the investment appears during deal-making or litigation.

Item 404(a) of Regulation S-K regulatory

"not a party to any transaction, or series of transactions, required to be disclosed pursuant to Item 404(a)"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What executive change did Seer, Inc. (SEER) announce on September 14, 2026?

Seer, Inc. reported that David Horn resigned as President, Chief Financial Officer and Treasurer to pursue other interests, effective October 1, 2026. The company states his resignation is not due to any disagreement related to its operations.

Who will take over the President role at Seer, Inc. (SEER)?

Effective October 1, 2026, Seer appointed Omid Farokhzad, M.D., already Chief Executive Officer and Chair of the Board, to also serve as President. He continues under his existing compensation arrangements with the company.

Who is the new principal financial officer of Seer, Inc. (SEER)?

Seer appointed Charles Endweiss, currently Vice President, Financial Planning & Analysis, as Treasurer and as the company’s principal financial officer and principal accounting officer, effective October 1, 2026.

How is Seer, Inc. handling David Horn’s stock options after his resignation?

Seer has offered to extend the post-termination exercise period of Mr. Horn’s vested and exercisable options to one year after his last day of service, subject to earlier expiration under plan terms and his signing and not revoking a separation and release agreement.

Does Seer, Inc. disclose any related-party concerns about Charles Endweiss?

The company states no arrangements or understandings with other persons regarding Mr. Endweiss’s appointment, no family relationships with directors or officers, and that he is not involved in any transaction requiring disclosure under Item 404(a) of Regulation S-K.

What prior experience does Seer’s new principal financial officer have?

Charles Endweiss, age 49, has been Seer’s Vice President, Financial Planning & Analysis since January 2021 and previously served as Head of Business Operations, Oral Health at Carbon from August 2017 to January 2021, with earlier roles in accounting, finance and operations.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 09/18/2026 - 04:07 PM Accepted by SEC EDGAR 09/18/2026 - 04:06 PM Learn about SEC filing dates

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported):

September 14, 2026

Seer, Inc.

(Exact name of registrant as specified in its charter)

Delaware		001-39747		82-1153150
(State or other jurisdiction of incorporation)		(Commission File Number)		(I.R.S. Employer Identification No.)

3800 Bridge Parkway, Suite 102

Redwood City, California 94065

(Address of principal executive offices, including zip code)

650-453-0000

(Registrant’s telephone number, including area code)

Not Applicable

(Former name or former address, if changed since last reports)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class		Trading Symbol		Name of each exchange on which registered
Class A Common Stock, par value $0.00001 per share		SEER		The NASDAQ Global Select Market
		Indicate by check mark whether
Preferred Stock Purchase Rights		N/A		The NASDAQ Global Select Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On September 14, 2026, David Horn resigned as the President, Chief Financial Officer and Treasurer of Seer, Inc. (the “Company”) to pursue other interests, effective as of October 1, 2026. Mr. Horn’s resignation is not the result of any disagreement with the Company related to its operations. The Company thanks Mr. Horn for his dedication over many years of service to the Company.

The Company has offered to extend the post-termination exercise period of all of Mr. Horn’s options to purchase shares of the Company’s Class A common stock, to the extent vested and exercisable at the time of his resignation’s effectiveness, until one year following Mr. Horn’s last day of service to the Company, subject to earlier expiration or termination in accordance with the applicable Company equity plan, and subject to Mr. Horn executing and not revoking a separation and release agreement with the Company.

In connection with Mr. Horn’s resignation, on September 17, 2026, the Board appointed Omid Farokhzad, M.D. to the office of President of the Company, in addition to his current positions as Chief Executive Officer and Chair of the Board, and Charles Endweiss, Vice President, Financial Planning & Analysis of the Company as Treasurer of the Company, each effective as of October 1, 2026. Mr. Endweiss will also serve as the principal financial officer and principal accounting officer of the Company as such terms are used for purposes of the rules and regulations of the Securities and Exchange Commission.

Charles Endweiss, age 49, has served as the Company’s Vice President, Financial Planning & Analysis since January 2021. Prior to joining the Company, Mr. Endweiss served as Head of Business Operations, Oral Health at Carbon, a provider of end-to-end digital 3D printing and manufacturing platform, from August 2017 to January 2021. Earlier in his career, Mr. Endweiss held a range of accounting, finance, and business operations positions at various technology companies. He holds a B.A. in Business from the University of Illinois, Urbana-Champaign and an M.B.A. from Santa Clara University.

Mr. Endweiss entered into an indemnification agreement on the Company’s standard form, a copy of which was filed as Exhibit 10.1 to the Company’s registration statement on Form S-1 (File No. 333-250035) on November 12, 2020.

Dr. Farokhzad and Mr. Endweiss are each continuing under the terms of their existing compensation arrangements with the Company. There are no arrangements or understandings between Mr. Endweiss and any other persons in connection with Mr. Endweiss’ appointment as the principal financial officer and principal accounting officer. Mr. Endweiss does not have any family relationships with any directors or officers of the Company. Mr. Endweiss is not a party to any transaction, or series of transactions, required to be disclosed pursuant to Item 404(a) of Regulation S-K.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

				SEER, INC.
Date: September 18, 2026
				By:		/s/ Omid Farokhzad
						Omid Farokhzad, M.D. Chief Executive Officer

Filing Exhibits & Attachments

3 documents

Other Documents

• EX-101 XBRL TAXONOMY EXTENSION SCHEMA 3.1 KB
• EX-101 XBRL TAXONOMY EXTENSION LABEL LINKBASE 17.6 KB
• EX-101 XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE 11.0 KB