Septerna plans potential sale of 29,000 common shares

Septerna (SEPN) filed to permit the sale of common stock by an affiliate.

Rhea-AI Filing Summary

Septerna (SEPN) filed to permit the sale of common stock by an affiliate. The notice covers the potential sale of 29,000 shares of common stock, to be handled through Morgan Stanley Smith Barney LLC Executive Financial Services. The shares are associated with an exercise of stock options on 08/11/2026, with an indicated aggregate value of $1,126,650.00. The filing also notes that 4,000 shares of common stock were sold in the past three months on 07/15/2026 under a Rule 10b5-1 trading plan for Elizabeth P. Bhatt, for proceeds of $135,974.00.

Key Figures

Shares to be sold: 29,000 shares Aggregate value of planned shares: $1,126,650.00 Past 3-month sale volume: 4,000 shares +2 more

5 metrics

Shares to be sold 29,000 shares Common stock covered by the notice with Morgan Stanley Smith Barney LLC

Aggregate value of planned shares $1,126,650.00 Indicated aggregate value for 29,000 common shares

Past 3-month sale volume 4,000 shares Common shares sold on 07/15/2026 under a 10b5-1 plan

Proceeds from prior 10b5-1 sale $135,974.00 Sale for Elizabeth P. Bhatt on 07/15/2026

Option exercise date 08/11/2026 Exercise of stock options associated with 29,000 common shares

Key Terms

Form 144, Exercise of Stock Options, Rule 10b5-1, Executive Financial Services

4 terms

Form 144 regulatory

"144: Securities Information Common | Morgan Stanley Smith Barney LLC"

Form 144 is a document that investors must file with the government when they plan to sell a large number of shares of a company's stock. It helps ensure transparency so everyone knows how many shares are being sold and when, which can impact the stock's price.

Exercise of Stock Options financial

"Common | 08/11/2026 | Exercise of Stock Options | Issuer"

Rule 10b5-1 regulatory

"10b5-1 Sales for ELIZABETH P. BHATT 250 East Grand Avenue"

Rule 10b5-1 is a regulation that allows company insiders to buy or sell their shares at predetermined times, even if they have access to non-public information. It acts like setting a schedule in advance for transactions, helping prevent accusations of unfair trading. This rule provides a way for insiders to plan trades transparently, giving investors confidence that these transactions are not based on hidden information.

Executive Financial Services financial

"Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does Septerna (SEPN) disclose in this Form 144 filing?

Septerna (SEPN) discloses a planned sale of 29,000 common shares linked to stock option exercises on 08/11/2026, with an indicated aggregate value of $1,126,650.00, plus details of prior 10b5-1 sales.

How many Septerna (SEPN) shares are covered for potential sale and what is their value?

The filing covers a potential sale of 29,000 shares of Septerna common stock with an indicated aggregate value of $1,126,650.00. These shares are tied to an exercise of stock options dated 08/11/2026.

What prior Septerna (SEPN) stock sales are reported in the past three months?

The document reports that 4,000 common shares of Septerna were sold on 07/15/2026 under a Rule 10b5-1 trading plan for Elizabeth P. Bhatt, generating proceeds of $135,974.00.

Who is the broker involved in the potential Septerna (SEPN) share sale?

The broker named is Morgan Stanley Smith Barney LLC Executive Financial Services, located at 1 New York Plaza, 8th Floor, New York, NY 10004. It is listed in connection with the planned sale of 29,000 Septerna common shares.

What is the nature of the transaction for the 29,000 Septerna (SEPN) shares?

The 29,000 Septerna common shares are linked to an exercise of stock options on 08/11/2026, with the transaction type indicated as cash. The filing provides advance notice for potential resales of these shares.

On which market are the Septerna (SEPN) shares referenced in this filing listed?

The common shares referenced in the filing are listed on NASDAQ. The notice relates to a potential sale of 29,000 NASDAQ-listed Septerna common shares associated with stock option exercises.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 08/11/2026 - 04:29 PM Accepted by SEC EDGAR 08/11/2026 - 04:28 PM Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001748622
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	Septerna, Inc.
SEC File Number	001-42382
Address of Issuer	250 East Grand Avenue South San Francisco CALIFORNIA 94080
Phone	650-338-3533
Name of Person for Whose Account the Securities are To Be Sold	ELIZABETH P. BHATT
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza 8th Floor New York NY 10004	29000	1126650.00	46676947	08/11/2026	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	08/11/2026	Exercise of Stock Options	Issuer			29000	08/11/2026	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
10b5-1 Sales for ELIZABETH P. BHATT 250 East Grand Avenue South San Francisco CA 94080	Common	07/15/2026	4000	135974.00

144: Remarks and Signature

Remarks	The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale.
Date of Notice	08/11/2026
Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1	10/20/2025
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ Elizabeth Bhatt
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)