Serina Therapeutics (SER) Chief Scientific Officer option exercise and share sale

Rhea-AI Filing Summary

Serina Therapeutics, Inc. reported an insider transaction by its Chief Scientific Officer on 12/22/2025. The officer exercised a stock option to buy 5,673 shares of common stock at an exercise price of $0.06 per share and on the same day sold 5,673 shares at a weighted average price of $2.6737 per share. The sale price reflects multiple trades at prices ranging from $2.705 to $2.66. After these transactions, the reporting person held 0 shares of common stock directly but continued to hold 356,286 stock options, which are fully vested and exercisable for common stock until 05/06/2031.

Insider Trade Summary

Net Seller: 5,673 shares ($15,168)

Net Sell 3 txns

Insider Moreadith Randall

Role Chief Scientific Officer

Sold 5,673 shs ($15K)

Type	Security	Shares	Price	Value
Exercise	Stock Option (right to buy)	5,673	$0.00	--
Exercise	Common Stock	5,673	$0.06	$340.38
Sale	Common Stock	5,673	$2.6737	$15K

Holdings After Transaction: Stock Option (right to buy) — 356,286 shares (Direct); Common Stock — 5,673 shares (Direct)

Footnotes (1)

1. The price reported in Column 4 of Table I is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.705 to $2.66. The reporting person undertakes to provide to Serina Therapeutics, Inc., any security holder of Serina Therapeutis, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4. The stock options are fully vested.

Form 4 Insider Transactions: What Each Field Means →

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Moreadith Randall

(Last) (First) (Middle)

601 GENOME WAY, SUITE 2001

(Street)

HUNTSVILLE AL 35806

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Serina Therapeutics, Inc. [ SER ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Scientific Officer

3. Date of Earliest Transaction (Month/Day/Year)
12/22/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	12/22/2025		M		5,673	A	$0.06	5,673	D
Common Stock	12/22/2025		S		5,673	D	$2.6737(1)	0	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (right to buy)	$0.06	12/22/2025		M			5,673	(2)	05/06/2031	Common Stock	5,673	$0	356,286	D

Explanation of Responses:

1. The price reported in Column 4 of Table I is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.705 to $2.66. The reporting person undertakes to provide to Serina Therapeutics, Inc., any security holder of Serina Therapeutis, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4.

2. The stock options are fully vested.

Remarks:

	/s/ Randall Moreadith	12/23/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transaction did Serina Therapeutics (SER) disclose?

Serina Therapeutics disclosed that its Chief Scientific Officer exercised stock options for 5,673 shares of common stock at $0.06 per share and sold 5,673 shares of common stock on 12/22/2025.

At what prices were the Serina Therapeutics (SER) shares sold in this Form 4?

The 5,673 shares of Serina Therapeutics common stock were sold at a weighted average price of $2.6737 per share, in multiple transactions at prices ranging from $2.705 to $2.66.

How many Serina Therapeutics (SER) shares does the insider own after this transaction?

Following the reported transactions, the insider directly owned 0 shares of Serina Therapeutics common stock but retained stock options on additional shares.

How many Serina Therapeutics (SER) stock options does the insider still hold?

After the transaction, the reporting person beneficially owned 356,286 stock options, which are fully vested and remain outstanding.

When do the remaining Serina Therapeutics (SER) stock options expire?

The remaining stock options held by the insider are exercisable and have an expiration date of 05/06/2031, according to the disclosure.

What is the role of the reporting person at Serina Therapeutics (SER)?

The reporting person is an officer of Serina Therapeutics, serving as the company’s Chief Scientific Officer, as indicated in the filing.