Serina Therapeutics CSO exercises options, sells 3,555 SER shares

Serina Therapeutics, Inc. insider trading report: the company’s Chief Scientific Officer exercised a stock option for 3,555 shares of common stock at an exercise price of $0.06 per share on 12/11/2025 and sold the same 3,555 shares the same day.

Rhea-AI Filing Summary

Serina Therapeutics, Inc. insider trading report: the company’s Chief Scientific Officer exercised a stock option for 3,555 shares of common stock at an exercise price of $0.06 per share on 12/11/2025 and sold the same 3,555 shares the same day. The reported sale had a weighted average price of $3.2404 per share, based on multiple trades between $3.20 and $3.35. After these transactions, the reporting person held no shares of common stock directly but continued to hold 366,886 stock options that remain fully vested.

Insider Trade Summary

Exercise and Sale: 3,555 shares ($11K approx. pre-tax spread)

Exercise and Sale 3 txns

Insider Moreadith Randall

Role Chief Scientific Officer

Sold 3,555 shs ($12K)

Approx. gross sale proceeds $12K

Approx. exercise cost $213.30

Approx. pre-tax spread $11K

Type	Security	Shares	Price	Value
Exercise	Stock Option (right to buy)	3,555	$0.00	$0.00
Exercise	Common Stock	3,555	$0.06	$213.30
Sale	Common Stock	3,555	$3.2404	$12K

Holdings After Transaction: Stock Option (right to buy) — 366,886 contracts (Direct); Common Stock — 0 shares (Direct)

Footnotes (2)

1. F1. The price reported in Column 4 of Table I is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.20 to $3.35. The reporting person undertakes to provide to Serina Therapeutics, Inc., any security holder of Serina Therapeutis, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4.
2. F2. The stock options are fully vested.

FAQ

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What insider transaction did Serina Therapeutics (SER) disclose in this Form 4?

The Chief Scientific Officer of Serina Therapeutics, Inc. reported exercising a stock option for 3,555 shares of common stock at $0.06 per share on 12/11/2025 and selling those 3,555 shares the same day.

What price did the Serina Therapeutics (SER) insider receive for the shares sold?

The reported sale price was a weighted average of $3.2404 per share, with multiple trades executed between $3.20 and $3.35.

How many Serina Therapeutics (SER) shares does the insider own after this transaction?

After the reported exercise and sale, the insider held 0 shares of Serina Therapeutics common stock directly.

How many stock options does the Serina Therapeutics (SER) insider still hold?

Following the transaction, the insider continued to hold 366,886 stock options, each exercisable for Serina Therapeutics common stock.

What are the key terms of the exercised Serina Therapeutics (SER) stock option?

The exercised option covered 3,555 shares of common stock at an exercise price of $0.06 per share, with an expiration date of 05/06/2031. The filing notes that these stock options were fully vested.

Who is the reporting person in the Serina Therapeutics (SER) Form 4 filing?

The reporting person is an officer of Serina Therapeutics, Inc., serving as the company’s Chief Scientific Officer.

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Accepted by SEC EDGAR 12/12/2025 - 12:48 PM EST Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Moreadith Randall

(Last) (First) (Middle)

601 GENOME WAY, SUITE 2001

(Street)

HUNTSVILLE AL 35806

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Serina Therapeutics, Inc. [ SER ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Scientific Officer

3. Date of Earliest Transaction (Month/Day/Year)
12/11/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	12/11/2025		M		3,555	A	$0.06	3,555	D
Common Stock	12/11/2025		S		3,555	D	$3.2404(1)	0	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (right to buy)	$0.06	12/11/2025		M			3,555	(2)	05/06/2031	Common Stock	3,555	$0	366,886	D

Explanation of Responses:

1. The price reported in Column 4 of Table I is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.20 to $3.35. The reporting person undertakes to provide to Serina Therapeutics, Inc., any security holder of Serina Therapeutis, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4.

2. The stock options are fully vested.

Remarks:

	/s/ Randall Moreadith	12/12/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.