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Serina Therapeutics, Inc.'s Chief Scientific Officer, Randall Moreadith, reported insider equity transactions dated 12/12/2025. He acquired 1,700 shares of common stock at $0.06 per share and, on the same date, sold 1,700 shares at a weighted average price of $3.2597, with sale prices ranging from $3.25 to $3.275. After these transactions, he directly held 0 shares of common stock.
The report also lists a stock option (right to buy) with an exercise price of $0.06 per share, covering 1,700 underlying shares in this transaction and expiring on 05/06/2031. Following the activity, 365,186 derivative securities (stock options) are shown as beneficially owned, and the stock options are described as fully vested.
Serina Therapeutics, Inc. insider trading report: the company’s Chief Scientific Officer exercised a stock option for 3,555 shares of common stock at an exercise price of $0.06 per share on 12/11/2025 and sold the same 3,555 shares the same day. The reported sale had a weighted average price of $3.2404 per share, based on multiple trades between $3.20 and $3.35. After these transactions, the reporting person held no shares of common stock directly but continued to hold 366,886 stock options that remain fully vested.
Serina Therapeutics, Inc. reported insider stock transactions by its Chief Scientific Officer on a Form 4. On December 9, 2025, the officer exercised stock options to buy 600 shares of common stock at an exercise price of $0.06 per share, then sold 600 shares at a weighted average price of $3.3133 per share, with individual sale prices ranging from $3.31 to $3.315. On December 10, 2025, the officer similarly exercised options for 645 shares at $0.06 per share and sold 645 shares at $3.35 per share.
The filing shows these transactions as direct ownership and notes that the related stock options, which carry an exercise price of $0.06 and expire on May 6, 2031, are fully vested. After the reported option exercises, the officer holds 370,441 stock options with the same exercise price.
Serina Therapeutics, Inc. reported that it has submitted a complete response to the U.S. Food and Drug Administration’s clinical hold letter for SER-252, its lead program for advanced Parkinson's disease. The company disclosed that the FDA’s clinical hold letter for SER-252 was dated November 25, 2025, and that its response was submitted on December 10, 2025. Serina also issued a press release on this regulatory update, which is included as an exhibit to the report and incorporated by reference.
Serina Therapeutics, Inc. reported transactions by its Chief Scientific Officer involving stock options and common stock in early December 2025. On December 2, 2025, the officer exercised stock options to acquire 1,500 shares of common stock at an exercise price of $0.06 per share, then sold 1,500 shares at a weighted average price of $3.9052 per share. On December 3, 2025, the officer exercised additional options for 5,000 shares at $0.06 per share and sold 5,000 shares at a weighted average price of $3.5246 per share.
After these transactions, the officer reported owning no shares of common stock directly, while continuing to hold 371,686 stock options with an exercise price of $0.06 per share, expiring on May 6, 2031. The weighted average sale prices reflect multiple trades within price ranges disclosed in the footnotes, and the options involved in these sales are fully vested.
Serina Therapeutics, Inc. (SER) reported an insider equity transaction by its Chief Scientific Officer on 11/25/2025. The officer exercised a stock option to buy 5,965 shares of common stock at an exercise price of $0.06 per share, then sold 5,965 shares of common stock at a weighted average price of $3.9001 per share, with individual sale prices ranging from $3.90 to $3.91.
After these transactions, the officer directly beneficially owned 5,965 shares of common stock and held 378,186 stock options directly. The filing notes that the reported sale price is a weighted average and the officer will provide details of the individual trade prices upon request.
Serina Therapeutics, Inc. reported an insider equity transaction by its Chief Scientific Officer. On 11/24/2025, the officer exercised a stock option to acquire 535 shares of common stock at an exercise price of $0.06 per share and then sold 535 shares of common stock on the same date.
The sale price reported for these shares is a weighted average of $3.935 per share, with individual sales executed at prices ranging from $3.917 to $3.98. Following these transactions, the reporting person holds 384,151 derivative securities in the form of stock options that remain beneficially owned and are fully vested.
Serina Therapeutics, Inc. officer reports option exercise and share sale. The company’s Chief Scientific Officer exercised stock options for 6,500 shares of common stock at an exercise price of $0.06 per share on 11/18/2025. On the same date, 6,500 shares of common stock were sold in an open market transaction at a weighted average price of $3.7541 per share, leaving 0 shares of common stock directly owned after the transaction. The filing also shows that 384,686 stock options with a $0.06 exercise price remained beneficially owned following the reported transactions, and these options are fully vested with an expiration date of 05/06/2031.
Serina Therapeutics furnished an 8-K announcing its financial results for the quarter ended September 30, 2025. The results are provided in a press release attached as Exhibit 99.1.
The company stated this information is furnished, not filed, under the Exchange Act and is not incorporated by reference except as specifically set forth. The filing lists the company’s common stock trading on NYSE American under the symbol SER.
Serina Therapeutics reported Q3 2025 results marked by losses and liquidity pressure. The company posted a net loss of $4.6 million for the quarter and $15.9 million for the nine months ended September 30, 2025, with no Q3 revenue and $0.1 million in grant revenue year to date. Cash and cash equivalents were $8.6 million as of September 30, 2025. Management states there is substantial doubt about the company’s ability to continue as a going concern.
Operating cash outflow was $11.9 million for the nine‑month period. To bolster liquidity, Serina raised capital through a $4.9 million private placement of Series A preferred stock, $2.2 million of net proceeds via an at‑the‑market program, and drew $5.0 million from a new unsecured convertible note that provides up to $20 million across clinical milestones. The FDA placed a clinical hold on the IND for SER‑252 on November 3, 2025, requesting additional information on an excipient. Shares outstanding were 10,664,064 as of November 10, 2025.