STOCK TITAN

Sol-Gel insider Opaleye buys 1,683 shares around $69

Opaleye Management Inc., a more-than-10% owner of Sol-Gel Technologies, reports open-market purchases of SLGL ordinary shares through affiliated investment vehicles.

(Moderate)
(Positive)
Form Type
4

Rhea-AI Filing Summary

Sol-Gel Technologies Ltd. (SLGL) had insider activity reported by Opaleye Management Inc., a more-than-10% owner. On September 1–2, 2026, entities it manages purchased 1,683 ordinary shares of Sol-Gel in open-market or private transactions at prices around $68.94–$69.52 per share, held indirectly through a fund and a managed account. A managed account associated with Opaleye Management Inc. held 15,000 ordinary shares after these transactions. No Rule 10b5-1 trading plan is reported, and Opaleye Management Inc. disclaims beneficial ownership beyond its pecuniary interest.

Positive

  • None.

Negative

  • None.
Insider Opaleye Management Inc.
Role 10% Owner
Bought 1,683 shs ($116K)
Type Security Shares Price Value
Purchase Ordinary Shares, par value NIS 1.00 per share F3, F1, F4 900 $68.9489 $62K
Purchase Ordinary Shares, par value NIS 1.00 per share F1, F4 783 $69.52 $54K
holding Ordinary Shares, par value NIS 1.00 per share F2, F4 -- -- --
Holdings After Transaction: Ordinary Shares, par value NIS 1.00 per share — 526,900 shares (Indirect, By Opaleye, L.P.); Ordinary Shares, par value NIS 1.00 per share — 15,000 shares (Indirect, By Managed Account)
Footnotes (4)
  1. F1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
  2. F2. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
  3. F3. The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $68.94-$68.95 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
  4. F4. Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Shares purchased September 2, 2026 900 shares Ordinary shares bought indirectly via Opaleye, L.P.
Weighted average purchase price September 2, 2026 $68.9489 per share Multiple trades in a range of $68.94–$68.95
Shares purchased September 1, 2026 783 shares Ordinary shares bought indirectly via Opaleye, L.P.
Purchase price September 1, 2026 $69.52 per share Open-market or private transaction
Total reported shares purchased 1,683 shares Net buy across September 1–2, 2026
Managed account holdings 15,000 shares Ordinary shares held indirectly by a separately managed account
weighted average price financial
"The price reported in column 4 is a weighted average price."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
separately managed account financial
"Securities owned by a separately managed account (the "Managed Account")."
A separately managed account (SMA) is a personalized investment portfolio owned by a single investor and run by a professional manager who buys and sells securities on that investor’s behalf. It matters to investors because an SMA offers tailored asset selection, tax handling, and transparency—like hiring a personal chef who prepares meals to your dietary needs rather than sharing a set menu—so you can align holdings with your goals and see exactly what you own.
pecuniary interest financial
"disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest"
beneficially own financial
"may be deemed to beneficially own the securities owned directly by the Fund."
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.

FAQ

What insider transactions did Opaleye Management Inc. report for SLGL?

Opaleye Management Inc. reported purchases totaling 1,683 ordinary shares of Sol-Gel Technologies Ltd. on September 1–2, 2026, in open-market or private transactions, held indirectly through Opaleye, L.P. and a separately managed account.

How many Sol-Gel (SLGL) shares does the managed account linked to Opaleye hold?

A separately managed account for which Opaleye Management Inc. serves as portfolio manager held 15,000 ordinary shares of Sol-Gel Technologies Ltd. indirectly as of September 1, 2026, according to the reported holdings entry.

Were the SLGL insider purchases made under a Rule 10b5-1 trading plan?

No. The filing indicates that no Rule 10b5-1 trading plan is reported for these Sol-Gel Technologies Ltd. transactions, so the purchases are not affirmatively identified as being made under a pre-arranged trading plan.

Who is considered to own the Sol-Gel (SLGL) shares in this Form 4?

The shares are owned directly by Opaleye, L.P. and a separately managed account. As investment manager and portfolio manager, Opaleye Management Inc. may be deemed to beneficially own them but disclaims beneficial ownership except to the extent of its pecuniary interest.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Learn about SEC filing dates
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Opaleye Management Inc.

(Last)(First)(Middle)
ONE BOSTON PLACE, 26TH FLOOR

(Street)
BOSTON MASSACHUSETTS 02108

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Sol-Gel Technologies Ltd. [ SLGL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
DirectorX10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
09/01/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Ordinary Shares, par value NIS 1.00 per share09/01/2026P783A$69.52526,000IBy Opaleye, L.P.(1)(4)
Ordinary Shares, par value NIS 1.00 per share09/02/2026P900A$68.9489(3)526,900IBy Opaleye, L.P.(1)(4)
Ordinary Shares, par value NIS 1.00 per share15,000IBy Managed Account(2)(4)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
2. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
3. The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $68.94-$68.95 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
4. Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Opaleye Management, Inc., By: /s/ James Silverman, President09/03/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)