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Form 4: Griffiths Richard Ian reports acquisition/exercise transactions in SLN

(Neutral)
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Griffiths Richard Ian reported acquisition or exercise transactions in a Form 4 filing for SLN. The filing lists transactions totaling 5,484,320 shares from August 10, 2026 to August 10, 2026.

Positive

  • None.

Negative

  • None.
Insider Griffiths Richard Ian
Role 10% Owner
Sold 5,484,320 shs
Type Security Shares Price Value
Sale American Depositary Shares F1, F2 2,792,826 -- --
Sale American Depositary Shares F1, F2 100,000 -- --
Sale American Depositary Shares F1, F2 50,000 -- --
Sale American Depositary Shares F1, F2 3,500 -- --
Sale American Depositary Shares F1, F2 800,000 -- --
Sale American Depositary Shares F1, F2 382,000 -- --
Sale American Depositary Shares F1, F2 470,820 -- --
Sale American Depositary Shares F1, F2 605,174 -- --
Sale American Depositary Shares F1, F2 120,000 -- --
Sale American Depositary Shares F1, F2 60,000 -- --
Sale American Depositary Shares F1, F2 100,000 -- --
Holdings After Transaction: American Depositary Shares — 67,650,464 shares (Indirect, See footnote)
Footnotes (2)
  1. F1. Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.
  2. F2. The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.
Largest ADS block reported 2,792,826 American Depositary Shares One of the derivative transactions dated 2026-08-10
Underlying ordinary shares for largest block 8,378,478 ordinary shares Ordinary shares underlying 2,792,826 ADS at 3-to-1 ratio
ADS to ordinary share ratio 1 ADS : 3 ordinary shares Each ADS immediately convertible into three ordinary shares
Sample ADS transaction size 800,000 American Depositary Shares One reported derivative transaction on 2026-08-10
Underlying shares for 800,000 ADS 2,400,000 ordinary shares Ordinary shares underlying 800,000 ADS at 3-to-1 ratio
American Depositary Share financial
"Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares"
An American Depositary Share (ADS) is a U.S.-listed certificate that represents a specified number of shares in a foreign company, held by a custodian bank; it works like a receipt that allows U.S. investors to buy and trade foreign equity on American exchanges without dealing with another country’s markets. Investors care because ADSs make foreign stocks easier to access, improve liquidity and settlement in dollars, and can affect dividend payments, voting rights and regulatory oversight compared with buying the underlying foreign shares directly.
ordinary shares financial
"convertible into three ordinary shares for no consideration and has no expiration date"
Ordinary shares are a type of ownership stake in a company, giving shareholders a right to participate in the company’s profits and decision-making through voting. They are similar to owning a piece of a business, and their value can rise or fall based on the company's performance. Investors buy ordinary shares to potentially earn dividends and benefit from the company's growth over time.
indirect ownership financial
"The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited"
beneficial ownership financial
"Mr. Griffiths disclaims beneficial ownership of these securities except to the extent"
Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.
pecuniary interest financial
"except to the extent of his proportionate pecuniary interest therein"

FAQ

What insider activity did SLN major holder Richard Griffiths report?

Richard Ian Griffiths, a more than 10% owner of Silence Therapeutics (SLN), reported multiple derivative transactions in American Depositary Shares on 2026-08-10, involving ADS convertible into ordinary shares at a 3-to-1 ratio.

How many Silence Therapeutics ADS were in the largest reported transaction?

One reported transaction involved 2,792,826 American Depositary Shares (ADS), corresponding to 8,378,478 ordinary shares. This block was part of a series of ADS transactions disclosed for 2026-08-10.

What is the conversion ratio between SLN ADS and ordinary shares?

Each Silence Therapeutics American Depositary Share (ADS) is immediately convertible into three ordinary shares for no consideration and has no expiration date, according to the disclosure footnotes.

Which entities were involved in the SLN ADS transactions reported by Griffiths?

The ADS were sold by Cream Capital Limited, Blake Holdings Limited, Ora Ventures Limited, Ora Capital Limited, Sarossa Plc, Pinkeys Limited, and Richard Griffiths personally, as described in the footnotes to the filing.

Does Richard Griffiths claim full beneficial ownership of the reported SLN securities?

No. Richard Griffiths disclaims beneficial ownership of the reported securities except to the extent of his proportionate pecuniary interest, reflecting that many shares are held through controlled entities.

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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Griffiths Richard Ian

(Last)(First)(Middle)

(Street)
ST HELIERY9JE2 3RR

(City)(State)(Zip)

JERSEY

(Country)
2. Issuer Name and Ticker or Trading Symbol
Silence Therapeutics plc [ SLN ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
DirectorX10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
08/10/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
American Depositary Shares$1608/10/2026S2,792,826 (1) (1)Ordinary Shares8,378,478(1)7,488,660ISee footnote(2)
American Depositary Shares$15.5808/10/2026S100,000 (1) (1)Ordinary Shares300,000(1)7,388,660ISee footnote(2)
American Depositary Shares$16.0908/10/2026S50,000 (1) (1)Ordinary Shares150,000(1)7,338,660ISee footnote(2)
American Depositary Shares$16.3508/10/2026S3,500 (1) (1)Ordinary Shares10,500(1)7,335,160ISee footnote(2)
American Depositary Shares$1608/10/2026S800,000 (1) (1)Ordinary Shares2,400,000(1)6,535,160ISee footnote(2)
American Depositary Shares$1608/10/2026S382,000 (1) (1)Ordinary Shares1,146,000(1)6,153,160ISee footnote(2)
American Depositary Shares$16.0908/10/2026S470,820 (1) (1)Ordinary Shares1,412,460(1)5,682,340ISee footnote(2)
American Depositary Shares$1608/10/2026S605,174 (1) (1)Ordinary Shares1,815,522(1)5,077,166ISee footnote(2)
American Depositary Shares$1608/10/2026S120,000 (1) (1)Ordinary Shares360,000(1)4,957,166ISee footnote(2)
American Depositary Shares$16.3508/10/2026S60,000 (1) (1)Ordinary Shares180,000(1)4,897,166ISee footnote(2)
American Depositary Shares$1608/10/2026S100,000 (1) (1)Ordinary Shares300,000(1)4,797,166ISee footnote(2)
Explanation of Responses:
1. Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.
2. The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.
/s/ Richard Ian Griffiths08/13/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)