[Form 4] Simulations Plus, Inc. Insider Trading Activity

Insider Trade Summary

Net Seller: 20,000 shares ($366,623)

Net Sell 2 txns

Insider WOLTOSZ WALTER S, WOLTOSZ VIRGINIA E

Role Director, 10% Owner | 10% Owner

Sold 20,000 shs ($367K)

Type	Security	Shares	Price	Value
Sale	Common Stock	7,776	$17.94	$140K
Sale	Common Stock	12,224	$18.58	$227K

Holdings After Transaction: Common Stock — 3,316,381 shares (Direct)

Footnotes (1)

1. The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons. These shares were sold in multiple transactions at prices falling within those ranges set forth in footnotes (3) and (4) of this Form 4. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the relevant footnotes. These shares were sold in multiple transactions at prices ranging from $17.35 to $18.33, inclusive. These shares were sold in multiple transactions at prices ranging from $18.35 to $18.91, inclusive.

Form 4 Insider Transactions: What Each Field Means →

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

WOLTOSZ WALTER S

(Last) (First) (Middle)

800 PARK OFFICES DRIVE

SUITE 401

(Street)

RESEARCH TRIANGLE PARK NC 27709

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Simulations Plus, Inc. [ SLP ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
07/01/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	07/01/2025		S(1)		7,776	D	$17.94(2)(3)	3,316,381	D
Common Stock	07/01/2025		S(1)		12,224	D	$18.58(2)(4)	3,304,157	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person^*

WOLTOSZ WALTER S

(Last) (First) (Middle)

800 PARK OFFICES DRIVE

SUITE 401

(Street)

RESEARCH TRIANGLE PARK NC 27709

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer

X	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

WOLTOSZ VIRGINIA E

(Last) (First) (Middle)

800 PARK OFFICES DRIVE

SUITE 401

(Street)

RESEARCH TRIANGLE PARK NC 27709

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

Explanation of Responses:

1. The sales reported in this Form 4 were effected automatically pursuant to a Rule 10b5-1 plan adopted by the reporting persons.

2. These shares were sold in multiple transactions at prices falling within those ranges set forth in footnotes (3) and (4) of this Form 4. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the relevant footnotes.

3. These shares were sold in multiple transactions at prices ranging from $17.35 to $18.33, inclusive.

4. These shares were sold in multiple transactions at prices ranging from $18.35 to $18.91, inclusive.

Remarks:

	/s/ Daniel Hoeft, attorney-in-fact for Walter S. Woltosz and Virginia E. Woltosz	07/02/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.