[10-Q] Silexion Therapeutics Corp Quarterly Earnings Report
Silexion Therapeutics Corp (SLXN) is a clinical-stage biotech developing SIL204, a second-generation siRNA targeting mutant KRAS in oncology. The company reported a net loss of $4.238 million for the six months ended June 30, 2025 and had $3.466 million of cash and cash equivalents on hand at that date. Operating cash outflow for the six months was $4.96 million and the accumulated deficit was $47.5 million. Management disclosed substantial doubt about the company’s ability to continue as a going concern for 12 months without additional financing.
The company completed equity financings in January 2025 (gross proceeds ~$5.0 million) and inducement warrant exercises raising ~$3.276 million through June 30, 2025, and used an equity line of credit (ELOC) raising an aggregate of $3.1 million through June 30, 2025. Nasdaq trading and listing matters required two reverse share splits (1-for-9 and 1-for-15) and the company received a hearings panel decision allowing continued listing subject to a compliance plan to reach $2.5 million of shareholders equity by September 19, 2025.
Silexion Therapeutics Corp (SLXN) è una biotech in fase clinica che sviluppa SIL204, un siRNA di seconda generazione diretto contro il KRAS mutato in oncologia. La società ha registrato una perdita netta di $4.238 milioni per i sei mesi terminati il 30 giugno 2025 e disponeva di $3.466 milioni in contanti e mezzi equivalenti a tale data. Il deflusso di cassa operativo nei sei mesi è stato di $4.96 milioni e il disavanzo accumulato ammontava a $47.5 milioni. La direzione ha espresso dubbi sostanziali sulla capacità dell'azienda di continuare come impresa in funzionamento per 12 mesi senza finanziamenti aggiuntivi.
La società ha completato finanziamenti azionari a gennaio 2025 (proventi lordi ~$5.0 milioni) ed esercizi di warrant incentivanti che hanno raccolto ~$3.276 milioni fino al 30 giugno 2025, e ha utilizzato una linea di credito azionaria (ELOC) raccogliendo un totale di $3.1 milioni fino al 30 giugno 2025. Questioni relative al trading e alla quotazione Nasdaq hanno richiesto due frazionamenti inversi delle azioni (1-per-9 e 1-per-15) e la società ha ottenuto una decisione del panel di audizione che consente la continuazione della quotazione a condizione di un piano di conformità per raggiungere $2.5 milioni di patrimonio netto entro il 19 settembre 2025.
Silexion Therapeutics Corp (SLXN) es una biotecnológica en fase clínica que desarrolla SIL204, un siRNA de segunda generación dirigido al KRAS mutado en oncología. La compañía informó una pérdida neta de $4.238 millones en los seis meses terminados el 30 de junio de 2025 y disponía de $3.466 millones en efectivo y equivalentes en esa fecha. El flujo de caja operativo en el semestre fue de $4.96 millones y el déficit acumulado ascendía a $47.5 millones. La dirección declaró que existen dudas sustanciales sobre la capacidad de la empresa para continuar como empresa en funcionamiento durante 12 meses sin financiamiento adicional.
La compañía completó financiamientos de capital en enero de 2025 (ingresos brutos ~$5.0 millones) y ejercicios de warrants de incentivo que recaudaron ~$3.276 millones hasta el 30 de junio de 2025, y utilizó una línea de crédito accionaria (ELOC) recaudando un total de $3.1 millones hasta el 30 de junio de 2025. Asuntos de negociación y listado en Nasdaq requirieron dos redistribuciones inversas de acciones (1-por-9 y 1-por-15) y la compañía recibió una decisión del panel de audiencias que permite la continuidad de la cotización sujeta a un plan de cumplimiento para alcanzar $2.5 millones de patrimonio neto para el 19 de septiembre de 2025.
Silexion Therapeutics Corp (SLXN)는 돌연변이 KRAS를 표적하는 2세대 siRNA인 SIL204를 개발 중인 임상 단계의 바이오 기업입니다. 회사는 2025년 6월 30일로 끝나는 6개월 동안 순손실 $4.238 million을 기록했으며, 같은 시점에 현금 및 현금성 자산 $3.466 million을 보유하고 있었습니다. 6개월간 영업 현금 유출은 $4.96 million이었고 누적 적자는 $47.5 million이었습니다. 경영진은 추가 자금 조달 없이는 향후 12개월 동안 계속기업으로 존속할 수 있는지에 대해 중대한 의문이 있다고 밝혔습니다.
회사는 2025년 1월에 주식형 자금 조달을 완료(총 수입 약 ~$5.0 million)했으며, 인센티브 워런트 행사로 2025년 6월 30일까지 약 $3.276 million을 조달했고, 주식담보 신용한도(ELOC)를 통해 2025년 6월 30일까지 총 $3.1 million을 조달했습니다. 나스닥 거래 및 상장 관련 문제로 두 차례의 액면병합(1대9 및 1대15)이 필요했으며, 청문회 패널은 2025년 9월 19일까지 주주지분을 $2.5 million으로 맞추는 준수 계획을 조건으로 상장 유지를 허용하는 결정을 내렸습니다.
Silexion Therapeutics Corp (SLXN) est une biotech en phase clinique développant SIL204, un siRNA de deuxième génération ciblant le KRAS mutant en oncologie. La société a déclaré une perte nette de $4.238 millions pour les six mois clos le 30 juin 2025 et détenait à cette date $3.466 millions de trésorerie et équivalents. La sortie de trésorerie d'exploitation sur six mois s'est élevée à $4.96 millions et le déficit cumulé était de $47.5 millions. La direction a exprimé des doutes importants quant à la capacité de la société à poursuivre son activité pendant 12 mois sans financement supplémentaire.
La société a réalisé des financements en capital en janvier 2025 (produits bruts ~$5.0 millions) et des exercices de bons d'incitation ayant levé ~$3.276 millions jusqu'au 30 juin 2025, et a utilisé une ligne de crédit en actions (ELOC) levant au total $3.1 millions jusqu'au 30 juin 2025. Des questions de négociation et de cotation au Nasdaq ont entraîné deux regroupements d'actions inverses (1 pour 9 et 1 pour 15) et la commission d'audition a rendu une décision permettant le maintien de la cotation sous réserve d'un plan de conformité visant à atteindre $2.5 millions de capitaux propres des actionnaires d'ici le 19 septembre 2025.
Silexion Therapeutics Corp (SLXN) ist ein Biotech-Unternehmen in der klinischen Phase, das SIL204 entwickelt, ein siRNA der zweiten Generation, das auf mutiertes KRAS in der Onkologie abzielt. Das Unternehmen meldete einen Nettoverlust von $4.238 Millionen für die sechs Monate zum 30. Juni 2025 und verfügte an diesem Stichtag über $3.466 Millionen an liquiden Mitteln. Der operative Cash-Abfluss für die sechs Monate betrug $4.96 Millionen und der kumulierte Fehlbetrag belief sich auf $47.5 Millionen. Das Management äußerte erhebliche Zweifel an der Fortführungsfähigkeit des Unternehmens für 12 Monate ohne zusätzliche Finanzierung.
Das Unternehmen schloss im Januar 2025 Eigenkapitalfinanzierungen ab (Bruttoerlöse ~$5.0 Millionen) und durch die Ausübung von Inducement-Warrants wurden bis zum 30. Juni 2025 ~$3.276 Millionen eingenommen; außerdem nutzte es eine Aktienkreditlinie (ELOC), die bis zum 30. Juni 2025 insgesamt $3.1 Millionen einbrachte. Handels- und Notierungsangelegenheiten an der Nasdaq erforderten zwei Reverse-Splits (1-für-9 und 1-für-15) und das Hearing-Panel traf die Entscheidung, die eine weitere Notierung unter der Bedingung eines Compliance-Plans erlaubt, wonach das Eigenkapital der Aktionäre bis zum 19. September 2025 $2.5 Millionen erreichen muss.
- Raised approximately $5.0 million in a public offering in January 2025 (gross proceeds)
- Generated ~$3.276 million from an induced warrant exercise in January 2025 and ~$1.8 million from a July/August 2025 inducement (reported as subsequent event)
- Cash and equivalents increased to $3.466 million as of June 30, 2025 (total cash, cash equivalents and restricted cash $3.544 million)
- Nasdaq hearings panel granted relief to remain listed, transferring the company to the Nasdaq Capital Market subject to a compliance plan
- Substantial doubt about going concern for at least 12 months was disclosed by management under ASC 205-40
- Accumulated deficit of $47.5 million and recurring operating losses (six-month net loss $4.238 million)
- Operating cash burn of $4.96 million for the six months ended June 30, 2025 exceeded cash on hand at period start
- Balance-sheet fragility: total liabilities $5.677 million versus shareholders' equity of $0.12 million at June 30, 2025
- Ongoing dilution risk from ELOC availability and multiple warrant issuances and inducement transactions (including replacement warrants)
- Nasdaq listing conditional on achieving at least $2.5 million of shareholders' equity by September 19, 2025, creating execution risk
Insights
TL;DR: Cash runway is limited; recurring operating losses and substantial doubt about going concern require near-term financing.
Detailed analysis: The company recorded a six-month net loss of $4.238 million and used $4.96 million of cash in operations, leaving $3.466 million of cash as of June 30, 2025. Despite successful equity transactions that generated gross proceeds of approximately $5.0 million and induced warrant exercises of $3.276 million, management states there is substantial doubt about the ability to continue as a going concern. The balance sheet shows total liabilities of $5.677 million versus shareholders' equity of $0.12 million, highlighting fragile solvency. Near-term capital raises or sustained operating improvements are required to meet the Nasdaq-mandated equity threshold and fund clinical development.
TL;DR: Governance actions (reverse splits, inducement transactions) address Nasdaq compliance but raise dilution and execution risk.
Detailed analysis: The company effected two reverse share splits (1-for-9 and 1-for-15) to address Nasdaq bid-price and listing-value deficiencies and received a conditional hearings panel decision requiring restoration of at least $2.5 million of shareholders' equity by September 19, 2025. The firm completed multiple warrant inducement transactions that produced proceeds (~$3.276M and later ~$1.8M) but also issued replacement warrants that could be exercised, creating potential future dilution. Related-party promissory notes of $3.19M remain on the balance sheet. The combination of conditional Nasdaq relief, ongoing financings, and contingent dilution presents execution risk for shareholders.
Silexion Therapeutics Corp (SLXN) è una biotech in fase clinica che sviluppa SIL204, un siRNA di seconda generazione diretto contro il KRAS mutato in oncologia. La società ha registrato una perdita netta di $4.238 milioni per i sei mesi terminati il 30 giugno 2025 e disponeva di $3.466 milioni in contanti e mezzi equivalenti a tale data. Il deflusso di cassa operativo nei sei mesi è stato di $4.96 milioni e il disavanzo accumulato ammontava a $47.5 milioni. La direzione ha espresso dubbi sostanziali sulla capacità dell'azienda di continuare come impresa in funzionamento per 12 mesi senza finanziamenti aggiuntivi.
La società ha completato finanziamenti azionari a gennaio 2025 (proventi lordi ~$5.0 milioni) ed esercizi di warrant incentivanti che hanno raccolto ~$3.276 milioni fino al 30 giugno 2025, e ha utilizzato una linea di credito azionaria (ELOC) raccogliendo un totale di $3.1 milioni fino al 30 giugno 2025. Questioni relative al trading e alla quotazione Nasdaq hanno richiesto due frazionamenti inversi delle azioni (1-per-9 e 1-per-15) e la società ha ottenuto una decisione del panel di audizione che consente la continuazione della quotazione a condizione di un piano di conformità per raggiungere $2.5 milioni di patrimonio netto entro il 19 settembre 2025.
Silexion Therapeutics Corp (SLXN) es una biotecnológica en fase clínica que desarrolla SIL204, un siRNA de segunda generación dirigido al KRAS mutado en oncología. La compañía informó una pérdida neta de $4.238 millones en los seis meses terminados el 30 de junio de 2025 y disponía de $3.466 millones en efectivo y equivalentes en esa fecha. El flujo de caja operativo en el semestre fue de $4.96 millones y el déficit acumulado ascendía a $47.5 millones. La dirección declaró que existen dudas sustanciales sobre la capacidad de la empresa para continuar como empresa en funcionamiento durante 12 meses sin financiamiento adicional.
La compañía completó financiamientos de capital en enero de 2025 (ingresos brutos ~$5.0 millones) y ejercicios de warrants de incentivo que recaudaron ~$3.276 millones hasta el 30 de junio de 2025, y utilizó una línea de crédito accionaria (ELOC) recaudando un total de $3.1 millones hasta el 30 de junio de 2025. Asuntos de negociación y listado en Nasdaq requirieron dos redistribuciones inversas de acciones (1-por-9 y 1-por-15) y la compañía recibió una decisión del panel de audiencias que permite la continuidad de la cotización sujeta a un plan de cumplimiento para alcanzar $2.5 millones de patrimonio neto para el 19 de septiembre de 2025.
Silexion Therapeutics Corp (SLXN)는 돌연변이 KRAS를 표적하는 2세대 siRNA인 SIL204를 개발 중인 임상 단계의 바이오 기업입니다. 회사는 2025년 6월 30일로 끝나는 6개월 동안 순손실 $4.238 million을 기록했으며, 같은 시점에 현금 및 현금성 자산 $3.466 million을 보유하고 있었습니다. 6개월간 영업 현금 유출은 $4.96 million이었고 누적 적자는 $47.5 million이었습니다. 경영진은 추가 자금 조달 없이는 향후 12개월 동안 계속기업으로 존속할 수 있는지에 대해 중대한 의문이 있다고 밝혔습니다.
회사는 2025년 1월에 주식형 자금 조달을 완료(총 수입 약 ~$5.0 million)했으며, 인센티브 워런트 행사로 2025년 6월 30일까지 약 $3.276 million을 조달했고, 주식담보 신용한도(ELOC)를 통해 2025년 6월 30일까지 총 $3.1 million을 조달했습니다. 나스닥 거래 및 상장 관련 문제로 두 차례의 액면병합(1대9 및 1대15)이 필요했으며, 청문회 패널은 2025년 9월 19일까지 주주지분을 $2.5 million으로 맞추는 준수 계획을 조건으로 상장 유지를 허용하는 결정을 내렸습니다.
Silexion Therapeutics Corp (SLXN) est une biotech en phase clinique développant SIL204, un siRNA de deuxième génération ciblant le KRAS mutant en oncologie. La société a déclaré une perte nette de $4.238 millions pour les six mois clos le 30 juin 2025 et détenait à cette date $3.466 millions de trésorerie et équivalents. La sortie de trésorerie d'exploitation sur six mois s'est élevée à $4.96 millions et le déficit cumulé était de $47.5 millions. La direction a exprimé des doutes importants quant à la capacité de la société à poursuivre son activité pendant 12 mois sans financement supplémentaire.
La société a réalisé des financements en capital en janvier 2025 (produits bruts ~$5.0 millions) et des exercices de bons d'incitation ayant levé ~$3.276 millions jusqu'au 30 juin 2025, et a utilisé une ligne de crédit en actions (ELOC) levant au total $3.1 millions jusqu'au 30 juin 2025. Des questions de négociation et de cotation au Nasdaq ont entraîné deux regroupements d'actions inverses (1 pour 9 et 1 pour 15) et la commission d'audition a rendu une décision permettant le maintien de la cotation sous réserve d'un plan de conformité visant à atteindre $2.5 millions de capitaux propres des actionnaires d'ici le 19 septembre 2025.
Silexion Therapeutics Corp (SLXN) ist ein Biotech-Unternehmen in der klinischen Phase, das SIL204 entwickelt, ein siRNA der zweiten Generation, das auf mutiertes KRAS in der Onkologie abzielt. Das Unternehmen meldete einen Nettoverlust von $4.238 Millionen für die sechs Monate zum 30. Juni 2025 und verfügte an diesem Stichtag über $3.466 Millionen an liquiden Mitteln. Der operative Cash-Abfluss für die sechs Monate betrug $4.96 Millionen und der kumulierte Fehlbetrag belief sich auf $47.5 Millionen. Das Management äußerte erhebliche Zweifel an der Fortführungsfähigkeit des Unternehmens für 12 Monate ohne zusätzliche Finanzierung.
Das Unternehmen schloss im Januar 2025 Eigenkapitalfinanzierungen ab (Bruttoerlöse ~$5.0 Millionen) und durch die Ausübung von Inducement-Warrants wurden bis zum 30. Juni 2025 ~$3.276 Millionen eingenommen; außerdem nutzte es eine Aktienkreditlinie (ELOC), die bis zum 30. Juni 2025 insgesamt $3.1 Millionen einbrachte. Handels- und Notierungsangelegenheiten an der Nasdaq erforderten zwei Reverse-Splits (1-für-9 und 1-für-15) und das Hearing-Panel traf die Entscheidung, die eine weitere Notierung unter der Bedingung eines Compliance-Plans erlaubt, wonach das Eigenkapital der Aktionäre bis zum 19. September 2025 $2.5 Millionen erreichen muss.
|
(Exact name of registrant as specified in its charter)
|
|
|
N/A
|
(State or other jurisdiction of
incorporation or organization)
|
|
(I.R.S. Employer
Identification No.)
|
|
(Address of Principal Executive Offices, including zip code)
|
|
(Registrant’s telephone number, including area code)
|
N/A
|
(Former name, former address and former fiscal year, if changed since last report)
|
Title of each class
|
|
Trading Symbol(s)
|
|
Name of each exchange on which registered
|
|
|
|
|
|
|
|
|
|
|
|
Large accelerated filer ☐
|
|
Accelerated filer ☐
|
|
|
|
Smaller reporting company
|
|
|
Emerging growth company
|
Page | ||
CERTAIN TERMS | ii | |
SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS | iv | |
PART I - FINANCIAL INFORMATION | 1 | |
Item 1. | Financial Statements | 1 |
Condensed Consolidated Balance Sheets (unaudited) | F-3 | |
Condensed Consolidated Statements of Operations (unaudited) | F-5 | |
Convertible Preferred Shares and Shareholders’ Equity (Capital Deficiency) (unaudited) | F-6 | |
Condensed Consolidated Statements of Cash Flows (unaudited) | F-7 | |
Notes to the Condensed Consolidated Financial Statements (unaudited) | F-9 | |
Item 2. | Management’s Discussion and Analysis of Financial Condition and Results of Operations | 2 |
Item 3. | Quantitative and Qualitative Disclosures about Market Risk | 17 |
Item 4. | Control and Procedures | 17 |
PART II - OTHER INFORMATION | 17 | |
Item 1. | Legal Proceedings | 17 |
Item 1A. | Risk Factors | 17 |
Item 2. | Unregistered Sales of Equity Securities and Use of Proceeds | 17 |
Item 3. | Defaults Upon Senior Securities | 18 |
Item 4. | Mine Safety Disclosures | 18 |
Item 5. | Other Information | 18 |
Item 6. | Exhibits | 18 |
SIGNATURES | 19 |
● | “we”, “us”, “our”, “the company”, “the Company”, “our company”, “the combined company”, “New Silexion”, or the “registrant” are to Silexion Therapeutics Corp (formerly known as Biomotion Sciences), a Cayman Islands exempted company, which is filing this Quarterly Report; | |
● | “A&R Sponsor Promissory Note” are to the convertible promissory note in a principal amount of $3,433,000 that our company issued to the Moringa sponsor at the Closing, in amendment and restatement of all promissory notes previously issued by Moringa to the sponsor for funds borrowed by Moringa from the sponsor between the initial public offering and the Closing of the Business Combination; | |
● | “Business Combination” are to the business combination transactions completed pursuant to the Business Combination Agreement, whereby, among other things: (i) Merger Sub 2 merged with and into Moringa, with Moringa continuing as the surviving company and a wholly-owned subsidiary of New Silexion; (ii) Merger Sub 1 merged with and into Silexion, with Silexion continuing as the surviving company and a wholly-owned subsidiary of New Silexion; (iii) the security holders of each of Moringa and Silexion exchanged their securities for securities of New Silexion at alternate, set exchange rates; (iv) the ordinary shares, warrants and units of Moringa were delisted from the Nasdaq Capital Market and deregistered under the Exchange Act; and (v) the ordinary shares and warrants of New Silexion issued in the Business Combination commenced trading on the Nasdaq Global Market; |
● | “Business Combination Agreement” are to the Amended and Restated Business Combination Agreement, dated April 3, 2024, by and among Moringa, New Silexion, August M.S. Ltd. (an Israeli company and a wholly owned subsidiary of New Silexion) (“Merger Sub 1”), Moringa Acquisition Merger Sub Corp (a Cayman Islands exempted company and a wholly owned subsidiary of New Silexion) (“Merger Sub 2”) and Silexion; |
● | “Closing” are to the closing of the Business Combination, which occurred on August 15, 2024; |
● | “Companies Law” are to the Companies Law (2021 Revision) of the Cayman Islands, as the same may be amended from time to time; |
● | “EarlyBird” or “EBC” are to EarlyBirdCapital, Inc., the representative of the underwriters of Moringa’s initial public offering; | |
● | “ELOC Agreement” or “White Lion Purchase Agreement” are to the Ordinary Share Purchase Agreement, dated August 13, 2024 and effective as of August 15, 2024, as amended as of January 14, 2025, by and between our company and White Lion Capital, LLC, which agreement established an equity line of credit (the “ELOC”) for our company; | |
● | “Exchange Act” are to the U.S. Securities Exchange Act of 1934, as amended; |
● | “initial public offering” or “IPO” are to Moringa’s initial public offering of its Class A ordinary shares and warrants, which was consummated in two closings, on February 19, 2021 and March 3, 2021; |
● | “Marketing Agreement” are to the Business Combination Marketing Agreement, dated February 16, 2021, entered into by Moringa with EarlyBird in connection with the IPO; |
● | “Moringa” are to Moringa Acquisition Corp, a Cayman Islands exempted company, which was formerly a special purpose acquisition company, and, after the Business Combination, is an inactive, wholly-owned subsidiary of New Silexion; |
● | “Moringa sponsor” or “sponsor” are to Moringa Sponsor, LP, a Cayman Islands exempted limited partnership, which served as the sponsor of Moringa, and include, where applicable, its affiliates (including Moringa’s initial shareholder, Moringa Sponsor US L.P., a Delaware limited partnership, which is a wholly-owned subsidiary of Moringa sponsor, and Greenstar, L.P., a Cayman Islands exempted limited partnership which has the same general partner as Moringa Sponsor, LP); |
● | “ordinary shares” are to our ordinary shares, par value $0.0135 per share; | |
● | “private warrants” are to the 1,408 warrants, in the aggregate, issued to the Moringa sponsor and EarlyBirdCapital pursuant to the Business Combination in exchange, on a one-for-one basis, for Moringa warrants sold to them in private placements simultaneously with the closings of the initial public offering; |
● | “public warrants” are to our 42,592 warrants that we issued pursuant to the Business Combination to holders of, and in a one-for-one exchange for, Moringa’s public warrants that were initially issued and sold in Moringa’s initial public offering; |
● | “SEC” are to the U.S. Securities and Exchange Commission; |
● | “Securities Act” are to the U.S. Securities Act of 1933, as amended; |
● | “Silexion” are to Silexion Therapeutics Ltd., an Israeli company, which following the Business Combination is a wholly-owned subsidiary of New Silexion; | |
● | “trust account” are to the U.S.-based trust account that was maintained by Continental Stock Transfer & Trust Company acting as trustee, into which the proceeds from Moringa’s initial public offering and concurrent private placement were deposited, which proceeds were reduced due to redemptions of publicly-held Moringa Class A ordinary shares prior to the Business Combination and the remaining funds of which (after payment of fees owed to EarlyBird and other service providers of Moringa for services provided prior to the Closing) were transferred to the Company upon the Closing of the Business Combination; |
● | “warrants” are to our warrants to purchase ordinary shares, consisting of (i) public warrants and private warrants issued pursuant to the Business Combination in exchange for warrants of Moringa, as well as (ii) warrants that we have issued and sold in public offering(s) and/or private placements subsequent to the Closing of the Business Combination; |
● | “2024 Annual Report” refer to our annual report on Form 10-K for the year ended December 31, 2024, which we filed with the SEC on March 18, 2025; and | |
● | “$,” “US$” and “U.S. dollar” each refer to the United States dollar. |
• | our ability to maintain the listing of our ordinary shares and warrants on Nasdaq; |
• | our current and planned pre-clinical and clinical studies and trials involving our product candidates; |
• | our future performance, including our projected timeline for regulatory approvals of our product candidates; |
• | our market opportunity; |
• | our strategy, future operations, financial position, projected costs, prospects and plans; |
• | expectations regarding the time during which we will be an emerging growth company under the JOBS Act; |
• | our ability to retain or recruit officers, key employees and directors; |
• | the impact of the regulatory environment and complexities with compliance related to such environment; |
• | expectations regarding future partnerships or other relationships with third parties; and |
• | our future capital requirements and sources and uses of cash, including our ability to obtain additional capital in the future. |
• | we are a development-stage company and have a limited operating history on which to assess our business; |
• | we have never generated any revenue from product sales and may never be profitable; |
• | we will need to raise substantial additional funding, which may not be available on acceptable terms, or at all, and which will cause dilution to our shareholders; |
• | the approach we are taking to discover and develop novel RNAi therapeutics is unproven for oncology and may never lead to marketable products; |
• | we do not have experience producing our product candidates at commercial levels, currently have no marketing and sales organization, have an uncertain market receptiveness to our product candidates, and are uncertain as to whether there will be insurance coverage and reimbursement for our potential products; |
• | we may be unable to attract, develop and/or retain our key personnel or additional employees required for our development and future success; |
• | we may issue additional ordinary shares or other equity securities without your approval, which would dilute your ownership interest and may depress the market price of our ordinary shares, including: (a) up to approximately $11.9 million of remaining ordinary shares issuable under the ELOC Agreement; (b) up to 44,000 ordinary shares, in the aggregate, underlying outstanding public warrants and private warrants (as of June 30, 2025); (c) $3,433,000 of ordinary shares underlying the A&R Sponsor Promissory Note; (d) up to 33,661 ordinary shares underlying remaining outstanding ordinary warrants and up to 17,284 ordinary shares underlying placement agent warrants, all of which warrants were issued in our January 2025 public offering facilitated by H.C. Wainwright as placement agent; (e) up to 18,464 ordinary shares and 304,212 ordinary shares issuable under remaining outstanding, and newly issued, investor warrants, respectively, and up to 10,368 ordinary shares and 10,647 ordinary shares underlying placement agent warrants, respectively, which were issued in warrant exercise inducement transactions facilitated by H.C. Wainwright in late January 2025 and early August 2025, respectively; and |
• | those additional factors described in “Part I, Item 1A. Risk Factors” of the 2024 Annual Report. |
Page | |
CONSOLIDATED FINANCIAL STATEMENTS: | |
Condensed Consolidated Balance Sheets (unaudited) | F-3 - F-4 |
Condensed Consolidated Statements of Operations (unaudited) | F-5 |
Condensed Consolidated Statements of Changes in Redeemable Convertible Preferred Shares and Shareholders’ Equity (Capital Deficiency) (unaudited) | F-6 - F-7 |
Condensed Consolidated Statements of Cash Flows (unaudited) | F-8 - F-9 |
Notes to Condensed Consolidated Financial Statements (unaudited) | F-10 - F-21 |
_____________________________________
_____________________
June 30,
|
December 31,
|
|||||||
2025
|
2024
|
|||||||
U.S. dollars in thousands
|
||||||||
Assets
|
||||||||
CURRENT ASSETS:
|
||||||||
Cash and cash equivalents
|
$
|
|
$
|
|
||||
Restricted cash
|
|
|
||||||
Prepaid expenses
|
|
|
||||||
Other current assets
|
|
|
||||||
TOTAL CURRENT ASSETS
|
|
|
||||||
NON-CURRENT ASSETS:
|
||||||||
Restricted cash
|
|
|
||||||
Long-term deposit
|
|
|
||||||
Property and equipment, net
|
|
|
||||||
Operating lease right-of-use asset
|
|
|
||||||
TOTAL NON-CURRENT ASSETS
|
|
|
||||||
TOTAL ASSETS
|
$
|
|
$
|
|
June 30,
|
December 31,
|
|||||||
2025
|
2024
|
|||||||
U.S. dollars in thousands
|
||||||||
Liabilities and shareholders’ equity (capital deficiency)
|
||||||||
CURRENT LIABILITIES:
|
||||||||
Trade payables
|
$
|
|
$
|
|
||||
Current maturities of operating lease liability
|
|
|
||||||
Employee related obligations
|
|
|
||||||
Accrued expenses and other account payable
|
|
|
||||||
Private warrants to purchase ordinary shares (including $* and $
|
*
|
|
||||||
Underwriters Promissory Note
|
|
|
||||||
TOTAL CURRENT LIABILITIES
|
|
|
||||||
NON-CURRENT LIABILITIES:
|
||||||||
Long-term operating lease liability
|
|
|
||||||
Related Party Promissory Note
|
|
|
||||||
TOTAL NON-CURRENT LIABILITIES
|
$
|
|
$
|
|
||||
TOTAL LIABILITIES
|
$
|
|
$
|
|
||||
SHAREHOLDERS' EQUITY (CAPITAL DEFICIENCY):
Ordinary shares ($
and December 31, 2024;
June 30, 2025 and December 31, 2024, respectively)
|
|
|
||||||
Additional paid-in capital
|
|
|
||||||
Accumulated deficit
|
(
|
)
|
(
|
)
|
||||
TOTAL SHAREHOLDERS' EQUITY (CAPITAL DEFICIENCY)
|
$
|
|
$
|
(
|
)
|
|||
TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY (CAPITAL DEFICIENCY)
|
$
|
|
$
|
|
Six months ended
June 30
|
Three months ended
June 30
|
|||||||||||||||
2025
|
2024
|
2025
|
2024
|
|||||||||||||
U.S. dollars in thousands
|
U.S. dollars in thousands
|
|||||||||||||||
OPERATING EXPENSES:
|
||||||||||||||||
Research and development (including $
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
General and administrative (including $
|
|
|
|
|
||||||||||||
TOTAL OPERATING EXPENSES
|
|
|
|
|
||||||||||||
OPERATING LOSS
|
|
|
|
|
||||||||||||
Financial expenses, net (including $
|
|
|
|
|
||||||||||||
LOSS BEFORE INCOME TAX
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
INCOME TAX
|
|
|
|
|
||||||||||||
NET LOSS
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Attributable to:
|
||||||||||||||||
Equity holders of the Company
|
|
|
|
|
||||||||||||
Non-controlling interests
|
|
|
|
|
||||||||||||
$
|
|
$
|
|
$
|
|
$
|
|
|||||||||
LOSS PER SHARE, BASIC AND DILUTED
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
WEIGHTED AVERAGE NUMBER OF ORDINARY SHARES OUTSTANDING USED IN COMPUTATION OF BASIC AND DILUTED LOSS PER SHARE
|
|
|
|
|
Redeemable Convertible Preferred Shares
|
Ordinary shares
|
Additional
paid-in Capital |
Accumulated deficit
|
Total shareholders’ equity (capital deficiency)
|
Total redeemable convertible preferred shares and contingently redeemable non-controlling interests, net of shareholders’ equity (capital deficiency)
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Series A preferred shares
|
Series A-1 preferred shares
|
Series A-2 preferred shares
|
Series A-3 preferred shares
|
Series A-4 preferred shares
|
Contingently redeemable non-controlling
interests
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Shares
|
Amount
|
Shares
|
Amount
|
Shares
|
Amount
|
Shares
|
Amount
|
Shares
|
Amount
|
Amount
|
Shares
|
Amount
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
BALANCE AT JANUARY 1, 2024
|
|
$
|
|
|
$
|
|
|
$
|
|
|
$
|
|
|
$
|
|
$
|
|
|
*
|
$
|
|
$
|
(
|
)
|
$
|
(
|
)
|
$
|
|
|||||||||||||||||||||||||||||||||||||||
CHANGES DURING THE SIX MONTHS PERIOD ENDED JUNE 30, 2024 (unaudited):
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Exercise of options
|
|
**
|
*
|
*
|
*
|
*
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Share-based compensation
|
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Net loss
|
(
|
)
|
(
|
)
|
(
|
)
|
(
|
)
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
BALANCE AS OF JUNE 30, 2024
|
|
$
|
|
|
$
|
|
|
$
|
|
|
$
|
|
|
$
|
|
$
|
|
|
*
|
$
|
|
$
|
(
|
)
|
$
|
(
|
)
|
$
|
|
|||||||||||||||||||||||||||||||||||||||
BALANCE AT JANUARY 1, 2025
|
|
|
|
|
|
|
|
|
|
|
|
|
***
|
$ |
$
|
|
$
|
(
|
)
|
$
|
(
|
)
|
$
|
(
|
)
|
|||||||||||||||||||||||||||||||||||||||||||
CHANGES DURING THE SIX MONTHS PERIOD ENDED JUNE 30, 2025 (unaudited):
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Issuance of ordinary shares and warrants upon public offering, net of issuance costs and exercise of pre-funded warrants to ordinary shares (see Note 4(a))
|
|
|
|
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Exercise of warrants (see Note 4(a))
|
|
|
|
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Issuance of ordinary shares and warrants upon warrants inducement, net of issuance costs (see Note 4(b))
|
|
|
|
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Share-based compensation
|
|
* |
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Conversion of EarlyBird Promissory Note (see Note 5)
|
|
* |
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Net loss
|
(
|
)
|
(
|
)
|
(
|
)
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
BALANCE AS OF JUNE 30, 2025
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
|
$
|
|
$
|
|
$
|
(
|
)
|
$
|
|
$
|
|
Redeemable Convertible Preferred Shares
|
Ordinary shares
|
Additional
paid-in Capital |
Accumulated deficit
|
Total shareholders’ equity (capital deficiency)
|
Total redeemable convertible preferred shares and contingently redeemable non-controlling interests, net of capital deficiency
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Series A preferred shares
|
Series A-1 preferred shares
|
Series A-2 preferred shares
|
Series A-3 preferred shares
|
Series A-4 preferred shares
|
Contingently redeemable non-controlling
interests
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Shares
|
Amount
|
Shares
|
Amount
|
Shares
|
Amount
|
Shares
|
Amount
|
Shares
|
Amount
|
Amount
|
Shares
|
Amount
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
BALANCE AT MARCH 31, 2024
|
|
$
|
|
|
$
|
|
|
$
|
|
|
$
|
|
|
$
|
|
$
|
|
|
*
|
$
|
|
$
|
(
|
)
|
$
|
(
|
)
|
$
|
|
|||||||||||||||||||||||||||||||||||||||
CHANGES DURING THE THREE MONTHS PERIOD ENDED JUNE 30, 2024 (unaudited):
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Share-based compensation
|
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Net loss
|
(
|
)
|
(
|
)
|
(
|
)
|
(
|
)
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
BALANCE AS OF JUNE 30, 2024
|
|
$
|
|
|
$
|
|
|
$
|
|
|
$
|
|
|
$
|
|
$
|
|
|
*
|
$
|
|
$
|
(
|
)
|
$
|
(
|
)
|
$
|
|
|||||||||||||||||||||||||||||||||||||||
BALANCE AT MARCH 31, 2025
|
|
|
|
|
|
|
|
|
|
|
|
|
**
|
$ |
$
|
|
$
|
(
|
)
|
$
|
|
$
|
|
|||||||||||||||||||||||||||||||||||||||||||||
CHANGES DURING THE THREE MONTHS PERIOD ENDED JUNE 30, 2025 (unaudited):
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Share-based compensation
|
|
* |
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Net loss
|
(
|
)
|
(
|
)
|
(
|
)
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
BALANCE AS OF JUNE 30, 2025
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
-,
|
|
$
|
|
$
|
|
(
|
)
|
|
|
Six months ended
June 30
|
Three months ended
June 30
|
|||||||||||||||
2025
|
2024
|
2025
|
2024
|
|||||||||||||
U.S. dollars in thousands
|
U.S. dollars in thousands
|
|||||||||||||||
CASH FLOWS FROM OPERATING ACTIVITIES:
|
||||||||||||||||
Net loss
|
$
|
(
|
)
|
$
|
(
|
)
|
$
|
(
|
)
|
$
|
(
|
)
|
||||
Adjustments required to reconcile loss to net cash used in operating activities:
|
||||||||||||||||
Depreciation
|
|
|
|
|
||||||||||||
Share-based compensation expenses
|
|
|
|
|
||||||||||||
Non-cash financial expenses
|
|
|
|
|
||||||||||||
Changes in operating assets and liabilities:
|
||||||||||||||||
Increase in prepaid expenses
|
(
|
)
|
(
|
)
|
(
|
)
|
(
|
)
|
||||||||
Decrease (increase) in other current assets
|
(
|
)
|
(
|
)
|
(
|
)
|
|
|||||||||
Increase (decrease) in trade payable
|
(
|
)
|
(
|
)
|
(
|
)
|
|
|||||||||
Net change in operating lease
|
|
|
|
|
||||||||||||
Increase (decrease) in employee related obligations
|
(
|
)
|
|
|
(
|
)
|
||||||||||
Increase (decrease) in accrued expenses and other account payable
|
(
|
)
|
|
(
|
)
|
|
||||||||||
Net cash used in operating activities
|
(
|
)
|
(
|
)
|
(
|
)
|
(
|
)
|
||||||||
CASH FLOWS FROM INVESTING ACTIVITIES-
|
||||||||||||||||
Purchase of property and equipment
|
(
|
)
|
(
|
)
|
(
|
)
|
|
|||||||||
Net cash used in investing activities
|
(
|
)
|
(
|
)
|
(
|
)
|
|
|||||||||
CASH FLOWS FROM FINANCING ACTIVITIES:
|
||||||||||||||||
Exercise of options
|
|
*
|
|
|
||||||||||||
Proceeds from issuance of ordinary shares upon public offering
|
|
|
|
|
||||||||||||
Issuance costs related to public offering
|
(
|
)
|
|
(
|
)
|
|
||||||||||
Proceeds from exercise of warrants
|
|
|
|
|
||||||||||||
Proceeds from issuance of ordinary shares upon warrants inducement
|
|
|
|
|
||||||||||||
Issuance costs related to warrants inducement
|
(
|
)
|
|
(
|
)
|
|
||||||||||
Payment of Underwriters Promissory Note
|
(
|
)
|
*
|
|
|
|||||||||||
Net cash provided by (used in) financing activities
|
|
*
|
(
|
)
|
|
|||||||||||
INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH
|
|
(
|
)
|
(
|
)
|
(
|
)
|
|||||||||
EXCHANGE RATE DIFFERENCES ON CASH AND CASH EQUIVALENTS AND RESTRICTED CASH
|
|
(
|
)
|
|
(
|
)
|
||||||||||
BALANCE OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT BEGINNING OF PERIOD
|
|
|
|
|
||||||||||||
BALANCE OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT END OF PERIOD
|
$
|
|
$
|
|
$
|
|
$
|
|
Six months ended
June 30
|
Three months ended
June 30
|
|||||||||||||||
2025
|
2024
|
2025
|
2024
|
|||||||||||||
U.S. dollars in thousands
|
U.S. dollars in thousands
|
|||||||||||||||
Appendix A–
RECONCILIATION OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH REPORTED IN THE CONSOLIDATED BALANCE SHEETS:
|
||||||||||||||||
Cash and cash equivalents
|
|
|
|
|
||||||||||||
Restricted cash
|
|
|
|
|
||||||||||||
TOTAL CASH, CASH EQUIVALENTS AND RESTRICTED CASH SHOWN IN STATEMENT OF CASH FLOWS
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Appendix B - SUPPLEMENTARY INFORMATION:
|
||||||||||||||||
SUPPLEMENTARY INFORMATION ON INVESTING AND FINANCING ACTIVITIES NOT INVOLVING CASH FLOWS:
|
||||||||||||||||
Conversion of Promissory Note to ordinary shares
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:
|
||||||||||||||||
Interest paid
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Interest received
|
$
|
|
$
|
|
$
|
|
$
|
|
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED)
(U.S. dollars in thousands)
a. |
Silexion Therapeutics Corp (“New Silexion”) (hereinafter - the “Company” or the “Combined Company”) is an entity that was formed for the purpose of effecting the Transactions (see below), and now serves as a publicly-traded holding company of its subsidiaries — including Moringa Acquisition Corp (“Moringa” or “the SPAC”), a Cayman Islands exempted company and Silexion Therapeutics Ltd. (formerly known as Silenseed Ltd.) (“Silexion”), an Israeli limited company— after the closing of the Transactions (the “Closing”).
|
b. |
From its formation on April 2, 2024 until the consummation of the Transactions on August 15, 2024, the Company had no operations and had been formed for the sole purpose of entering into the Transactions and serving as the publicly-traded company following the Transactions. Silexion, on the other hand, as the accounting acquirer in the Transactions and the predecessor entity to the Company from an accounting perspective, had active operations during earlier periods of time, prior to the Transactions. Consequently, these financial statements reflect the financial information of Silexion (as the predecessor entity to the Company) until August 15, 2024 and the financial information of New Silexion (as the combined company following the Transactions) from that date forward.
|
c. |
On April 3, 2024, Silexion entered into an Amended and Restated Business Combination Agreement (hereinafter, the “A&R BCA”) with the SPAC, New Silexion, August M.S. Ltd. an Israeli company and wholly-owned subsidiary of New Silexion (“Merger Sub 1”), and Moringa Acquisition Merger Sub Corp, a Cayman Islands exempted company and wholly-owned subsidiary of New Silexion (“Merger Sub 2”). Under the A&R BCA, both Silexion and the SPAC were to become wholly-owned subsidiaries of New Silexion, which was to become a publicly-held, Nasdaq-listed entity (the A&R BCA and related transactions: the “Transactions”).
|
d. |
On August 15, 2024, the parties completed the Transactions pursuant to which Merger Sub 2 merged with and into the SPAC, with the SPAC continuing as the surviving company of such merger and a wholly-owned subsidiary of New Silexion (the “SPAC Merger”), and Merger Sub 1 merged with and into Silexion, with Silexion continuing as the surviving company of such merger and a wholly-owned subsidiary of New Silexion (the “Acquisition Merger”).
|
e. |
In connection with the closing of the Transactions, the ordinary shares and warrants of New Silexion are now listed on the Nasdaq Global Market and began trading under the symbols “SLXN” and “SLXNW”, respectively.
|
f. |
In October 2023, Israel was attacked by Hamas, a terrorist organization and entered a state of war. Since the commencement of these events, there have been additional active hostilities, including with Hezbollah in Lebanon, the Houthi movement which controls parts of Yemen, and with Iran. As of the date of these condensed consolidated financial statements, the war with Hamas is ongoing and continues to evolve. In response to ongoing Iranian aggression and support of proxy attacks against Israel, on June 12, 2025, Israel conducted a series of preemptive defensive air strikes in Iran targeting Iran’s nuclear program and military commanders. On June 24, 2025, a ceasefire had been reached and as of such date there has been no further escalation of hostilities between Israel and Iran; however, there is no assurance that the ceasefire will be upheld and military activity and hostilities may continue to exist at varying levels of intensity. Any or all of these situations may potentially escalate in the future to more violent events.
|
F - 10
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
g. |
On November 22, 2024, the Company announced a prospective
|
h. |
Going concern:
|
a. |
Unaudited Condensed Financial Statements
|
F - 11
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
b. |
Use of estimates
|
c. |
Restricted cash
|
d. |
Fair value measurement
|
Level 1: |
Quoted prices (unadjusted) in active markets that are accessible at the measurement date for assets or liabilities. The fair value hierarchy gives the highest priority to Level 1 inputs.
|
Level 2: |
Observable prices that are based on inputs not quoted on active markets, but corroborated by market data or active market data of similar or identical assets or liabilities.
|
Level 3 |
Unobservable inputs are used when little or no market data is available. The fair value hierarchy gives the lowest priority to Level 3 inputs.
|
F - 12
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
e. |
Concentration of credit risks
|
f. |
Recently adopted accounting pronouncements :
|
F - 13
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
a. |
Research and development expenses:
|
Six months ended
June 30
|
Three months ended
June 30
|
|||||||||||||||
2025
|
2024
|
2025
|
2024
|
|||||||||||||
Payroll and related expenses
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Share-based compensation expenses
|
|
|
|
|
||||||||||||
Subcontractors and consultants
|
|
|
|
|
||||||||||||
Rent and maintenance
|
|
|
|
|
||||||||||||
Other
|
|
|
|
|
||||||||||||
$
|
|
$
|
|
$
|
|
$
|
|
b. |
General and administrative expenses:
|
Payroll and related expenses
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Share-based compensation expenses
|
|
|
|
|
||||||||||||
Professional services
|
|
|
|
|
||||||||||||
Depreciation
|
|
|
|
|
||||||||||||
Rent and maintenance
|
|
|
|
|
||||||||||||
Patent registration
|
|
|
|
|
||||||||||||
Travel expenses
|
|
|
|
|
||||||||||||
Other
|
|
|
|
|
||||||||||||
|
$
|
|
$
|
|
$
|
|
c. |
Financial expense, net:
|
Change in fair value of financial liabilities measured at fair value
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Interest income, net
|
(
|
)
|
(
|
)
|
(
|
)
|
(
|
)
|
||||||||
Foreign currency exchange loss, net
|
|
|
|
|
||||||||||||
Other
|
|
|
|
|
||||||||||||
Total financial expense (income), net
|
$
|
|
$
|
|
$
|
|
$
|
|
a. |
Public Offering of Ordinary Shares, Pre-Funded Warrants, and Ordinary Warrants.
|
F - 14
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
b. |
Induced Warrant Exercise Transaction
|
F - 15
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
Number of options
|
Weighted-average
exercise price (in
U.S. dollars)
|
Weighted- average
remaining
contractual term
(in years)
|
Aggregate
intrinsic
value
|
|||||||||||||
Outstanding at January 1, 2025
|
|
|
|
-
|
||||||||||||
Granted
|
|
|
|
-
|
||||||||||||
Expired
|
(
|
)
|
|
-
|
-
|
|||||||||||
Outstanding at June 30, 2025
|
|
|
|
-
|
||||||||||||
Exercisable at June 30, 2025
|
|
|
|
-
|
||||||||||||
Vested and expected to vest at June 30, 2025
|
|
|
|
-
|
Six months ended
June 30
|
Three months ended
June 30
|
|||||||||||||||
2025
|
2024
|
2025
|
2024
|
|||||||||||||
Research and development
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
General and administrative
|
|
|
|
|
||||||||||||
$
|
|
$
|
|
$
|
|
$
|
|
F - 16
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
June 30, 2025
|
||||||||
Level 3
|
Total
|
|||||||
Financial Liabilities
|
||||||||
Private Warrants to ordinary shares
|
$
|
*
|
$
|
*
|
||||
Promissory Notes
|
$
|
|
$
|
|
December 31, 2024
|
||||||||
Level 3
|
Total
|
|||||||
Financial Liabilities
|
||||||||
Private Warrants to ordinary shares
|
$
|
|
$
|
|
||||
Promissory Notes
|
$
|
|
$
|
|
Six months ended
June 30, 2025
|
Three months ended
June 30, 2025
|
|||||||||||||||
Promissory Notes
|
Private Warrants to
ordinary shares
|
Promissory Notes
|
Private Warrants to
ordinary shares
|
|||||||||||||
Fair value at the beginning of the period
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Change in fair value
|
|
(
|
)
|
|
(
|
)
|
||||||||||
Repayments
|
(
|
)
|
|
|
|
|||||||||||
Conversion to equity
|
(
|
)
|
|
|
|
|||||||||||
Fair value at the end of the period
|
$
|
|
$
|
*
|
$
|
|
$
|
*
|
Six months ended
June 30, 2024
|
Three months ended
June 30, 2024
|
|||||||
Warrants to preferred shares
|
||||||||
Fair value at the beginning of the period
|
$
|
|
$
|
|
||||
Change in fair value
|
|
|
||||||
Fair value at the end of the period
|
$
|
|
$
|
|
F - 17
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
June 30
|
||||||||
|
2025
|
2024
|
||||||
Volatility
|
|
%
|
|
%
|
||||
Term (years) |
|
|
||||||
Dividend yield
|
|
%
|
|
%
|
Six months ended
June 30
|
Three months ended
June 30
|
|||||||||||||||
2025
|
2024
|
2025
|
2024
|
|||||||||||||
Numerator:
|
||||||||||||||||
Net loss
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Net loss attributable to ordinary shareholders, basic and diluted:
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Denominator:
|
||||||||||||||||
Weighted-average shares used in computing net loss per share attributable to ordinary shareholders, basic and diluted
|
|
|
|
|
||||||||||||
Net loss per share attributable to ordinary shareholders, basic and diluted
|
$
|
|
$
|
|
$
|
|
$
|
|
F - 18
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
- |
Warrants to purchase Ordinary Shares (see also Note 4).
|
- |
Share-based compensation;
|
- |
Promissory Notes (see also Note 5).
|
- |
Redeemable convertible preferred shares;
|
- |
Warrants to purchase redeemable convertible preferred shares;
|
- |
Share-based compensation;
|
a. |
Transactions:
|
Six months ended
June 30
|
Three months ended
June 30
|
|||||||||||||||
2025
|
2024
|
2025
|
2024
|
|||||||||||||
Share-based compensation included in research and development expenses
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Share-based compensation included in general and administrative expenses
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Financial expenses
|
$
|
|
$
|
|
$
|
|
$
|
|
b. |
Balances:
|
June 30,
2025
|
December 31,
2024
|
|||||||
Current liabilities —
|
||||||||
Private warrants to purchase ordinary shares
|
$
|
*
|
$
|
|
June 30,
2025
|
December 31,
2024
|
|||||||
Non-Current liabilities -
|
||||||||
Sponsor Promissory Note
|
$
|
|
$
|
|
F - 19
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
Six months ended June 30
|
Three months ended June 30
|
|||||||||||||||
2025
|
2024
|
2025
|
2024
|
|||||||||||||
Clinical trials and other payments to R&D-related service providers
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
R&D payroll and related expenses, other than share-based compensation
|
|
|
|
|
||||||||||||
R&D share-based compensation expenses
|
|
|
|
|
||||||||||||
G&A payroll and related expenses, other than share-based compensation
|
|
|
|
|
||||||||||||
G&A share-based compensation expenses
|
|
|
|
|
||||||||||||
G&A Professional services
|
|
|
|
|
||||||||||||
Depreciation expenses
|
|
|
|
|
||||||||||||
Other segment expenses (*)
|
|
|
|
|
||||||||||||
Operating loss
|
|
|
|
|
||||||||||||
Interest income
|
(
|
)
|
(
|
)
|
(
|
)
|
(
|
)
|
||||||||
Interest expense
|
|
|
|
|
||||||||||||
Other financing expense (income), net
|
|
|
|
|
||||||||||||
Income taxes
|
|
|
|
|
||||||||||||
Net loss
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Segment assets
|
$
|
|
$
|
|
$
|
|
$
|
|
||||||||
Expenditures for segment assets
|
$
|
(
|
)
|
$
|
(
|
)
|
$
|
|
$
|
|
||||||
Segment liabilities
|
$
|
|
$
|
|
$
|
|
$
|
|
F - 20
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) (continued)
(U.S. dollars in thousands)
a. |
Increase in Authorized Pool Under 2024 Equity Incentive Plan
|
b. |
Additional Reverse Share Split
|
c. |
Additional Warrant Inducement Transaction
|
• | apply for Orphan Drug Designation in both the U.S. and EU for our SIL204 product; |
• | conduct toxicological studies with respect to SIL204; |
• | initiate a clinical trial powered for statistical significance with respect to SIL204; |
• | seek marketing approvals for SIL204 in various territories; |
• | maintain, expand and protect our intellectual property portfolio; |
• | hire additional operational, clinical, quality control and scientific personnel; |
• | add additional product candidates to our pipeline; |
• | add operational, financial and management information systems and personnel, including personnel to support our product development, any future commercialization efforts and our status as a public company; and |
• | invest in research and development and regulatory approval efforts in order to utilize our technology as a platform focused on the silencing of the KRAS oncogene using RNA-interference therapeutics. |
• | on or before September 19, 2025, we are required to demonstrate in a report filed under the Exchange Act our restoration of compliance with, and our expected long-term compliance with, the shareholders’ equity requirement, as to be demonstrated in a balance sheet not older than 60 days to be included in such a filing; and |
• | if we fail to maintain compliance with any Nasdaq listing rule on or before November 18, 2025, we will be required to submit, and the Nasdaq hearings panel will review (as part of its maintenance of jurisdiction over our listing status until November 18, 2025), a compliance plan for the subject deficiency to determine whether the panel is willing to grant an exception to us to cure that deficiency. |
Six-month period ended June 30, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Operating expenses: | ||||||||
Research and development | $ | 1,608 | $ | 1,727 | ||||
General and administrative | 2,326 | 908 | ||||||
Total operating expenses | 3,934 | 2,635 | ||||||
Operating loss | 3,934 | 2,635 | ||||||
Financial expenses, net | 301 | 270 | ||||||
Loss before income tax | 4,235 | 2,905 | ||||||
Income tax | 3 | 7 | ||||||
Net loss | $ | 4,238 | $ | 2,912 |
Six-month period ended June 30, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Payroll and related expenses | $ | 854 | $ | 476 | ||||
Share-based compensation expenses | - | 38 | ||||||
Subcontractors and consultants | 598 | 1,128 | ||||||
Rent and maintenance | 95 | 49 | ||||||
Other | 61 | 36 | ||||||
Total research and development expenses | $ | 1,608 | $ | 1,727 |
Six-month period ended June 30, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Payroll and related expenses | $ | 739 | $ | 280 | ||||
Share-based compensation expenses | 58 | 26 | ||||||
Professional service | 1,111 | 448 | ||||||
Depreciation | 7 | 15 | ||||||
Rent and maintenance | 85 | 72 | ||||||
Patent registration | 51 | 25 | ||||||
Travel expenses | 91 | 16 | ||||||
Other | 184 | 26 | ||||||
Total general and administrative expenses | $ | 2,326 | $ | 908 |
Three-month period ended June 30, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Operating expenses: | ||||||||
Research and development | $ | 1,018 | $ | 766 | ||||
General and administrative | 1,266 | 619 | ||||||
Total operating expenses | 2,284 | 1,385 | ||||||
Operating loss | 2,284 | 1,385 | ||||||
Financial expenses, net | 216 | 102 | ||||||
Loss before income tax | 2,500 | 1,487 | ||||||
Income tax | 3 | 2 | ||||||
Net loss for the quarter | $ | 2,503 | $ | 1,489 |
Three-month period ended June 30, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Payroll and related expenses | $ | 485 | $ | 216 | ||||
Share-based compensation expenses | - | 19 | ||||||
Subcontractors and consultants | 442 | 497 | ||||||
Rent and maintenance | 55 | 18 | ||||||
Other | 36 | 16 | ||||||
Total research and development expenses | $ | 1,018 | $ | 766 |
Three-month period ended June 30, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Payroll and related expenses | $ | 407 | $ | 151 | ||||
Share-based compensation expenses | 37 | 13 | ||||||
Professional service | 586 | 369 | ||||||
Depreciation | 3 | 7 | ||||||
Rent and maintenance | 55 | 46 | ||||||
Patent registration | 47 | 16 | ||||||
Travel expenses | 37 | 7 | ||||||
Other | 94 | 10 | ||||||
Total general and administrative expenses | $ | 1,266 | $ | 619 |
Six-month period ended June 30, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Cash and cash equivalents and restricted cash at beginning of the period | $ | 1,270 | $ | 4,645 | ||||
Net cash used in operating activities | (4,960 | ) | (2,817 | ) | ||||
Net cash used in investing activities | (7 | ) | (6 | ) | ||||
Net cash provided by financing activities | 7,237 | - | ||||||
Net increase (decrease) in cash and cash equivalents and restricted cash | $ | 2,270 | $ | (2,823 | ) | |||
Translation adjustments on cash and cash equivalents and restricted cash | 4 | (75 | ) | |||||
Cash and cash equivalents and restricted cash at end of the period | $ | 3,544 | $ | 1,747 |
Three-month period ended June 30, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Cash and cash equivalents and restricted cash at beginning of the period | $ | 6,233 | $ | 2,831 | ||||
Net cash used in operating activities | (2,507 | ) | (1,065 | ) | ||||
Net cash used in investing activities | (1 | ) | - | |||||
Net cash used in financing activities | (195 | ) | - | |||||
Net increase (decrease) in cash and cash equivalents and restricted cash | $ | 2,703 | $ | (1,065 | ) | |||
Translation adjustments on cash and cash equivalents and restricted cash | 14 | (19 | ) | |||||
Cash and cash equivalents and restricted cash at end of the period | $ | 3,544 | $ | 1,747 |
• | Materials cost; |
• | Regulatory pathway; and |
• | Human clinical trial costs. |
• | significant dilution to the equity interests of our current shareholders; |
• | a deemed change of control of our company due to the issuance of a substantial number of ordinary shares, which may affect, among other things, our ability to use our net operating loss carry forwards, if any, and could result in a change in the officers and directors of our company relative to our current officers and directors, to the extent any shareholders build up significant beneficial ownership from ordinary shares issued pursuant to public offerings, warrant exercises or the ELOC; |
• | delaying or preventing a change of control of our company by diluting the share ownership or voting rights of a person seeking to obtain control; and |
• | an adverse effect on prevailing market prices for our ordinary shares or warrants. |
No. | Description of Exhibit | |
31.1* | Certification of Principal Executive Officer Pursuant to Securities Exchange Act Rules 13a-14(a) and 15(d)-14(a), as adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 | |
31.2* | Certification of Principal Financial Officer Pursuant to Securities Exchange Act Rules 13a-14(a) and 15(d)-14(a), as adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 | |
32.1** | Certification of Principal Executive Officer Pursuant to 18 U.S.C. Section 1350, as adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 | |
32.2** | Certification of Principal Financial Officer Pursuant to 18 U.S.C. Section 1350, as adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 | |
101.INS* | Inline XBRL Instance Document. | |
101.SCH* | Inline XBRL Taxonomy Extension Schema Document. | |
101.CAL* | Inline XBRL Taxonomy Extension Calculation Linkbase Document. | |
101.DEF* | Inline XBRL Taxonomy Extension Definition Linkbase Document. | |
101.LAB* | Inline XBRL Taxonomy Extension Label Linkbase Document. | |
101.PRE* | Inline XBRL Taxonomy Extension Presentation Linkbase Document. | |
104* | Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101). |
* | Filed herewith. |
** | Furnished herewith. |
SILEXION THERAPEUTICS CORP | ||
Date: August 12, 2025 | /s/ Ilan Hadar | |
Name: | Ilan Hadar | |
Title: | Chairman and Chief Executive Officer | |
(Principal Executive Officer) | ||
Date: August 12, 2025 | /s/ Mirit Horenshtein-Hadar | |
Name: | Mirit Horenshtein-Hadar | |
Title: | Chief Financial Officer | |
(Principal Financial and Accounting Officer) |