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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM
8-K
CURRENT
REPORT
Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934
Date of report (Date of earliest event reported):
November 9, 2026
Silexion Therapeutics
Corp
(Exact name of registrant as specified in its charter)
| Cayman Islands |
|
001-42253 |
|
N/A |
| (State or other jurisdiction |
|
(Commission File Number) |
|
(I.R.S. Employer |
| of incorporation) |
|
|
|
Identification No.) |
|
12 Abba Hillel Road
Ramat-Gan, Israel |
|
5250606 |
| (Address of principal executive offices) |
|
(Zip Code) |
+972-3-7564999
(Registrant’s telephone number, including
area code)
N/A
(Former name or former address, if changed since
last report)
Check the appropriate box below if the Form 8-K is intended to simultaneously
satisfy the filing obligation of the registrant under any of the following provisions:
| ☐ |
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |
| ☐ |
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |
| ☐ |
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |
| ☐ |
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |
Securities registered pursuant to Section 12(b)
of the Act:
| Title of each class |
|
Trading Symbol(s) |
|
Name of each exchange on
which registered |
| Ordinary Shares, par value $0.135 per share |
|
SLXN |
|
The Nasdaq Stock Market LLC |
| Warrants exercisable for Ordinary Shares at an exercise price of $15,525.00 per share |
|
SLXNW |
|
The Nasdaq Stock Market LLC |
Indicate by check mark whether the registrant is an emerging growth
company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange
Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company ☒
If an emerging growth company, indicate by check mark if the registrant
has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant
to Section 13(a) of the Exchange Act.
Item 8.01 Other Events.
Further to its previous reports, as well as the
approval of its shareholders received on October 26, 2026, on November 9, 2026, Silexion Therapeutics Corp, a Cayman Islands exempted
company (“Silexion” or the “Company”) issued a press release announcing a prospective 1-for-24 reverse share split
of all of its issued and outstanding, and authorized but unissued, ordinary shares. The reverse share split will become effective after
the close of the market on November 10, 2026, and the Company’s ordinary shares will begin trading on a reverse split-adjusted basis
on the Nasdaq Capital Market at the open of the market on November 11, 2026. The ticker symbol for the ordinary shares will remain “SLXN.”
The reverse share split will be effected automatically,
without any action required on the part of the Company’s shareholders. The reverse share split will result in a corresponding increase
in the par value of the Company’s ordinary shares, from $0.135 per share to $3.24 per share. No fractional shares will be issued
as a result of the reverse share split, as any fractional share totals as to which shareholders who are DTC participants become entitled
will be rounded up to the nearest whole number of shares. A copy of the press release announcing the reverse share split is attached as
Exhibit 99.1 to this report and is incorporated herein by reference.
Item 9.01 Financial Statements and Exhibits
(d) Exhibits
| 99.1 |
|
Press Release dated November 9, 2026, titled “Silexion Therapeutics Announces 1-for-24 Reverse Share Split” |
SIGNATURE
Pursuant to the requirements of the Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
| |
SILEXION THERAPEUTICS CORP |
| |
|
| Date: November 9, 2026 |
/s/ Ilan Hadar |
| |
Name: |
Ilan Hadar |
| |
Title: |
Chief Executive Officer |
Exhibit 99.1

Silexion Therapeutics
Announces 1-for-24 Reverse Share Split
Trading on a split-adjusted basis will begin
at market open on November 11, 2026.
This adjustment is expected to help Silexion
regain compliance with the Nasdaq minimum bid price requirement,
enhance its market position, and support its clinical progress with SIL204
Grand Cayman, Cayman Islands, November 9, 2026 -- Silexion Therapeutics
Corp. (NASDAQ: SLXN) (“Silexion” or the “Company”), a clinical-stage biotechnology company pioneering RNA interference
(RNAi) therapies for KRAS-driven cancers, today announced a 1-for-24 reverse share split of its ordinary shares. The reverse share split
will become effective after market close on November 10, 2026, and the Company’s ordinary shares will begin trading on a reverse
split-adjusted basis on the Nasdaq Capital Market at market open on November 11, 2026, under the existing ticker symbol “SLXN.”
The new CUSIP number that has been assigned to the post-reverse split shares (to begin trading on November 11, 2026) is G1281K163.
As a result of the reverse share split, every twenty-four (24) ordinary
shares of Silexion issued and outstanding will be automatically combined into one share. The par value of the ordinary shares will be
proportionately increased, from $0.135 per share to $3.24 per share, and no fractional shares will be issued. Shareholders that are direct
participants in the DTC system and that are entitled to fractional shares will each receive a rounded-up whole share.
“This reverse share split is a deliberate step to preserve our
Nasdaq listing and reinforce the capital structure that supports Silexion’s clinical execution,” said Ilan Hadar, Chairman
and CEO of Silexion. “Along with progressing in the active stage of our Phase 2/3 trial of SIL204 in locally advanced pancreatic
cancer (for which we dosed our first patient in September), we believe that we can achieve more solid financial standing in the capital
markets and remedy outstanding Nasdaq listing deficiencies. The higher per-share trading price that will result from this reverse split
should help to remedy our Nasdaq bid price deficiency, reduce volatility, broaden the universe of investors who are able to engage with
our story, and improve our flexibility to fund the continued advancement of our SIL204 treatment for patients with KRAS-driven cancers
who have few options today.”
Record shareholders holding shares in book-entry form do not need to
take any action in respect of the reverse share split, as their shares will be adjusted automatically. Those holding shares through a
broker or nominee will also not need to take any action, as the number of shares held by them will be adjusted automatically, as reflected
in their brokerage account. For further details, those shareholders should contact their broker.
The reverse share split is intended, among other things, to enable
the Company to regain compliance with Nasdaq’s minimum bid price requirement, as outlined in Nasdaq Listing Rule 5550(a)(2). This
adjustment is also expected to help enhance Silexion’s market position and support its strategic growth initiatives (including by
facilitating the Company’s conduct of equity financings).
About Silexion Therapeutics
Silexion Therapeutics is a pioneering clinical-stage, oncology-focused
biotechnology company dedicated to the development of innovative treatments for unsatisfactorily treated solid tumor cancers that have
the mutated KRAS oncogene, generally considered to be the most common oncogenic gene driver in human cancers. The Company conducted a
Phase 2a clinical trial in its first-generation product candidate, which showed a positive trend in comparison to the control of chemotherapy
alone, and is now advancing its lead, second-generation, product candidate, SIL204, a small interfering RNA (siRNA), through Phase 2/3
clinical evaluation. Silexion is committed to pushing the boundaries of therapeutic advancements in the field of oncology and further
developing its lead product candidate for locally advanced pancreatic cancer. For more information, please visit: https://silexion.com
Cautionary Note Regarding Forward-Looking Statements
This press release contains forward-looking statements within the meaning
of the federal securities laws. All statements other than statements of historical fact contained in this communication are forward-looking
statements, including, for example, statements regarding: the clinical development, timing, enrollment, protocol execution, and anticipated
outcomes of the Phase 2/3 clinical trial of SIL204 in locally advanced pancreatic cancer; the Company’s anticipated future financing
activities; the Company’s planned reverse share split and the timing of its effectiveness; the Company’s ability to remedy
its deficiencies in complying with the continued listing requirements of the Nasdaq Capital Market; the potential therapeutic benefits
and clinical utility of SIL204; Silexion’s business strategy and development plans; and Silexion’s future capital requirements
and ability to raise additional capital. These forward-looking statements are generally identified by terminology such as “may”,
“should”, “could”, “might”, “plan”, “possible”, “expect”, “intend”,
“will”, “estimate”, “anticipate”, “believe”, “predict”, “prospective”,
or “potential”, or the negatives of these terms or variations of them, or similar terminology. Forward-looking statements
involve a number of risks, uncertainties, and assumptions, and actual results or events may differ materially from those projected or
implied in those statements. Important factors that could cause such differences include, but are not limited to: (i) the ability of Silexion
and its participating clinical trial centers to successfully enroll, treat, and evaluate patients in accordance with the study protocol,
including the initial safety run-in cohort of approximately 18 patients and the randomized expansion cohort of approximately 166 patients;
(ii) the risk that preliminary clinical safety, tolerability, response rate, or survival data may not be achieved, confirmed, or replicated
as the trial advances, that early observations may not be predictive of final trial results, or that SIL204 may not demonstrate statistically
significant improvements in clinical efficacy compared to chemotherapy alone; (iii) the ability of Silexion to complete standard site
activation procedures at additional medical centers in Israel and Germany on anticipated timelines; (iv) Silexion’s strategy, future
operations, financial position, projected costs, prospects, and plans; (v) the impact of the regulatory environment and compliance complexities,
including site-level approvals, conditions, and clearances required prior to study commencement in each jurisdiction; (vi) Silexion’s
future capital requirements and sources and uses of cash, including its ability to obtain additional capital; (vii) whether Silexion can
maintain its Nasdaq listing, including its ability to remedy its Nasdaq listing deficiencies regarding minimum bid price and minimum shareholders’
equity; and (viii) other risks and uncertainties set forth in the documents filed by the Company with the SEC, including the Company’s
Annual Report on Form 10-K for the year ended December 31, 2025, filed with the SEC on March 17, 2026, and the Company’s Quarterly
Report on Form 10-Q for the quarters ended March 31, 2026 and June 30, 2026, filed with the SEC on May 15, 2026 and August 14, 2026, respectively.
Silexion cautions you against placing undue reliance on forward-looking statements, which reflect current beliefs and are based on information
currently available as of the date a forward-looking statement is made. Forward-looking statements set forth herein speak only as of the
date they are made. Silexion undertakes no obligation to revise forward-looking statements to reflect future events, changes in circumstances,
or changes in beliefs, except as otherwise required by law.
Company Contact
Silexion Therapeutics Corp
Ms. Mirit Horenshtein Hadar, CFO
info@silexion.com
Investor Relations Contact
Arx Investor Relations
North American Equities Desk
silexion@arxhq.com