Welcome to our dedicated page for Stoke Therapeutics SEC filings (Ticker: STOK), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Stoke Therapeutics, Inc. (Nasdaq: STOK) SEC filings page on Stock Titan provides access to the company’s official U.S. regulatory disclosures. As a Nasdaq Global Select Market issuer, Stoke files current reports, annual reports, and other documents that describe its financial condition, governance, and progress in developing RNA-based medicines such as zorevunersen for Dravet syndrome and STK-002 for Autosomal Dominant Optic Atrophy (ADOA).
Current reports on Form 8-K document material events, including quarterly financial results, clinical and collaboration milestones, and changes in executive leadership. For example, Stoke has used Form 8-K to announce results of operations, disclose the appointment of its Chief Executive Officer and related employment and severance agreements, and furnish press releases about the initiation and progress of the global Phase 3 EMPEROR study of zorevunersen and the Phase 1 OSPREY study of STK-002.
Amended current reports on Form 8-K/A provide additional detail or updates on previously reported items, such as the company’s decisions regarding the frequency of advisory shareholder votes on executive compensation. These filings offer insight into Stoke’s corporate governance practices and board decisions.
Through Stock Titan, investors can also track periodic filings such as Forms 10-K and 10-Q when available, which typically include detailed discussions of Stoke’s TANGO antisense platform, its rare disease pipeline, collaboration agreements, and risk factors. Form 4 and related insider transaction filings, when present, can help users monitor equity awards and share transactions by directors and officers.
Stock Titan enhances these documents with AI-powered summaries that highlight key points from lengthy filings, helping users quickly understand the significance of items such as clinical trial disclosures, collaboration terms, compensation arrangements, and shareholder voting outcomes. Real-time updates from the SEC’s EDGAR system ensure that new STOK filings, including 10-K, 10-Q, 8-K, and Form 4 submissions, are surfaced promptly for further review and analysis.
Stoke Therapeutics, Inc. (STOK) director reported an open-market sale of company stock. On 11/24/2025, the reporting person sold 40,472 shares of common stock at a weighted average price of $29.7173 per share, through multiple transactions within a price range of $29.50 to $30.12. After this sale, the director beneficially owned 323,774 shares of Stoke Therapeutics common stock in direct ownership form. The filing notes that the sale was made under a Rule 10b5-1 trading plan that was adopted on August 15, 2025.
Stoke Therapeutics, Inc.$26.6141 per share and 20,682 shares at a weighted average price of $27.3361 per share, in each case coded as an open market sale. After these transactions, the director beneficially owned 364,246 shares of Stoke Therapeutics common stock in direct form.
The filing states that the trades were executed under a Rule 10b5-1 trading plan adopted on August 15, 2025, which is designed to provide an affirmative defense for pre-arranged trading. The prices reported reflect multiple individual trades within stated price ranges, and the reporting person has agreed to provide detailed breakdowns of the prices upon request.
Stoke Therapeutics (STOK) disclosed insider sales by its Chief Medical Officer on 11/03/2025 under a pre‑arranged Rule 10b5-1 trading plan adopted on December 11, 2024. The transactions included 3,776 shares at a weighted average price of $25.2242 (range $24.74–$25.65), 1,455 shares at $26.0206 (range $25.79–$26.50), 600 shares at $27.54 (range $27.40–$27.60), and 100 shares at $29.35.
Following these sales, the reporting person directly beneficially owned 7,195 shares.
Stoke Therapeutics reported Q3 2025 results. Revenue was $10.6 million versus $4.9 million a year ago, with a net loss of $38.3 million (basic and diluted EPS of $0.65 loss). For the first nine months, revenue rose to $183.0 million and net income reached $51.0 million (diluted EPS $0.85), driven primarily by collaboration revenue.
Cash, cash equivalents and marketable securities totaled $328.6 million as of September 30, 2025. Stockholders’ equity increased to $308.1 million. The company recorded $150.8 million of license revenue and $11.5 million of development revenue year-to-date under its Biogen collaboration, following a $165.0 million upfront payment and 70/30 cost sharing. Deferred revenue was $14.3 million (current and long-term combined). The Phase 3 EMPEROR study of zorevunersen began in May 2025, with first patient dosed in August 2025.
After quarter-end, the company sold approximately 1.8 million shares for $48.7 million in net proceeds. Shares outstanding were 57,117,150 as of October 31, 2025.
Stoke Therapeutics, Inc. (STOK) filed an 8-K noting it issued a press release announcing financial results for the quarter ended September 30, 2025. The filing lists the press release as Exhibit 99.1 and identifies the company’s common stock as trading on the Nasdaq Global Select Market. This is a routine disclosure of quarterly results via press release.
Stoke Therapeutics (STOK) reported insider equity grants to its Chief Executive Officer and Director. On 10/08/2025, the reporting person received a stock option to buy 570,000 shares at $30.5 per share, expiring on 10/07/2035. The option vests as to 1/4 on 10/06/2026, then 1/48 monthly thereafter, subject to continued service.
The filing also reports 380,000 RSUs, each representing one share of common stock, vesting 1/4 annually on the sixth day of October, with the first tranche on 10/06/2026, subject to continued service. Ownership form for both awards is listed as direct.
Stoke Therapeutics director Edward M. Kaye reported transactions under a Rule 10b5-1 plan dated 12/30/2024. On 10/08/2025 he exercised a stock option with a $0.6 exercise price to acquire 25,000 shares and simultaneously sold 25,000 shares at $30 per share, leaving him with 49,124 shares beneficially owned. The option is fully vested; original vesting began on 10/17/2018 with monthly vesting thereafter, and the reporting was authorized by an attorney-in-fact on 10/10/2025. The filing indicates these actions were made pursuant to the 10b5-1 trading plan to satisfy the affirmative defense conditions.
Stoke Therapeutics (STOK) filed a Rule 144 notice for a proposed sale of 25,000 common shares acquired by an exercise of stock options on 10/08/2025. The shares are to be sold through Morgan Stanley Smith Barney LLC with an aggregate market value of $682,750 against 54,797,418 shares outstanding, indicating the block is a very small portion of the float. The filing shows the option exercise and cash payment both occurred on 10/08/2025, and the seller certifies no undisclosed material nonpublic information.
Related trading history lists 116,472 shares sold in the past three months by the same named insider, generating gross proceeds of $2,532,056.28, executed under a mix of 10b5-1 program and direct sales. These prior disposals and the new Rule 144 notice document routine insider liquidity rather than company operational changes.
Director Edward M. Kaye reported the sale of 42,461 shares of Stoke Therapeutics common stock on 10/03/2025 under a pre-existing Rule 10b5-1 trading plan. The filing shows a weighted-average sale price of $25.0867 (individual trades ranged from $25.00 to $25.30), leaving the reporting person with 49,124 shares beneficially owned after the transactions. The schedule was signed by an attorney-in-fact on 10/07/2025.
Jonathan Allan, General Counsel and Corporate Secretary of Stoke Therapeutics, Inc. (STOK), reported insider transactions dated 10/03/2025. Under a Rule 10b5-1 trading plan adopted on 12/12/2024, he exercised a stock option to acquire 10,000 shares at an exercise price of $9.15 per share and immediately sold 10,000 shares at a weighted-average price of $25.065 per share. The filings show the reporting person beneficially owned 21,831 shares before the sale and 11,831 shares after the sale; he also holds an option representing 10,000 underlying shares exercisable as of 10/03/2025 that expires on 03/14/2033, leaving 34,800 total shares and equivalents reported as beneficially owned following the transactions.