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Redmile Funds Invest $3.56M in Shattuck Labs PIPE; 9.99% Ownership Disclosed

Filing Impact
(Low)
Filing Sentiment
(Neutral)
Form Type
SCHEDULE 13D/A

Rhea-AI Filing Summary

Redmile Group and affiliated funds acquired warrants and pre-funded warrants in Shattuck Labs' private placement (PIPE) closed August 25, 2025, increasing their reported economic exposure to 6,379,095 shares of common stock, representing 9.99% of the outstanding class on the stated calculation basis.

The Redmile Funds paid approximately $3,555,190 in aggregate to purchase Pre-Funded Warrants and Common Warrants at a combined purchase price of $0.8676, with RBI II contributing approximately $1,777,211. The filing details registration rights for resale of Common Stock issuable on exercise and describes a Beneficial Ownership Blocker that limits actual exercises to prevent ownership above 9.99%.

Positive

  • Redmile Funds participated materially in the PIPE by investing approximately $3,555,190 to acquire Pre-Funded Warrants and Common Warrants.
  • Reported beneficial ownership equals 9.99%, making Redmile a clearly disclosed significant holder under Schedule 13D.
  • Registration Rights Agreement in place obligates the issuer to file to register resale of shares issuable upon exercise within 30 days, improving liquidity for those securities.

Negative

  • Board resignation: Michael Lee resigned from the Issuer's Board of Directors concurrent with the PIPE closing, although the filing states it was not due to disagreements with the issuer.
  • Beneficial Ownership Blocker limits immediate exercise: Warrants cannot be exercised to the extent doing so would cause beneficial ownership to exceed 9.99%, constraining the ability to convert warrants into voting shares without notice and adjustment.

Insights

TL;DR: Redmile raised economic exposure to Shattuck Labs via PIPE warrants, reporting a 9.99% beneficial position and registration rights for resale.

The transaction shows material participation by an institutional investor group: the Redmile Funds paid roughly $3.56 million to acquire Pre-Funded Warrants and Common Warrants allowing up to 8,195,460 underlying shares in aggregate (4,097,730 pre-funded plus 4,097,730 common), subject to the Beneficial Ownership Blocker. Reported beneficial ownership of 6,379,095 shares (9.99%) reflects currently exercisable and issuable shares limited by the ownership cap. The Registration Rights Agreement requires the issuer to file a registration statement within 30 days of closing to permit resale of the shares issuable upon exercise, which enhances liquidity for these securities. For investors, this is a material ownership disclosure and confirms Redmile as a significant holder with potential future share issuance tied to warrant exercise triggers.

TL;DR: Redmile's increased position and simultaneous board resignation are governance-relevant but described as non-contentious.

The amendment records Michael Lee's resignation from the Issuer's board concurrent with the PIPE closing and explicitly states the resignation "is not due to any disagreements" with the issuer on operations, policies or practices. Redmile and Jeremy C. Green disclaim beneficial ownership except to the extent of any pecuniary interest, while also disclosing shared voting and dispositive power over reported shares. The Beneficial Ownership Blocker and the ability to change the ownership limitation with 61 days' notice create a clear mechanism affecting future voting influence. These facts are material to governance assessment but the filing does not allege disputes or governance conflicts.






If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).






SCHEDULE 13D




Comment for Type of Reporting Person:
(1) The source of funds was working capital of certain private investment funds managed by Redmile Group, LLC (the "Redmile Funds"), including Redmile Biopharma Investments II, L.P. ("RBI II"). (2) Redmile Group, LLC's beneficial ownership of the Issuer's common stock ("Common Stock") is comprised of 5,539,724 shares of Common Stock owned by RBI II and certain other Redmile Funds. In addition, Redmile beneficially owns 112,936 shares of Common Stock that are issuable upon the exercise of certain vested options. The stock options were granted to Mike Lee, a managing director of Redmile, in connection with his service as a member of the Board of Directors and are exercisable within 60 days of the date of this filing. Pursuant to the policies of Redmile, Mr. Lee holds the stock options as a nominee on behalf, and for the sole benefit, of Redmile and has assigned all economic, pecuniary and voting rights in respect of the stock options to Redmile. Subject to the Beneficial Ownership Blocker (as defined below), Redmile Group, LLC may also be deemed to beneficially own 11,296,283 shares of Common Stock issuable upon exercise of certain pre-funded warrants and common warrants (the "Warrants"), including the Warrants purchased by RBI II and certain other Redmile Funds in the private placement (the "PIPE"). Pursuant to the terms of the Warrants, the Issuer may not effect any exercise of the Warrants, and a holder of a Warrants may not exercise the Warrants held by such holder, to the extent that after giving effect to such issuance after exercise, the holder (together with the holder's affiliates, any other persons deemed to be acting as a group together with the holder or any of its affiliates, or any other persons whose beneficial ownership of Common Stock would or could be aggregated with the holder's and/or its affiliates' for purposes of Section 13(d) or Section 16 of the Exchange Act), would beneficially own in excess of 9.99% (the "Beneficial Ownership Limitation") of the number of shares of Common Stock outstanding immediately after giving effect to the issuance of shares of Common Stock issued upon exercise of the Warrant (the "Beneficial Ownership Blocker"). The Beneficial Ownership Limitation may be changed at a holder's election upon 61 days' notice to the Issuer. The 6,379,095 shares of Common Stock reported as beneficially owned by Redmile Group, LLC in this Schedule 13D, which includes 726,435 shares of Common Stock issuable upon exercise of certain of the Warrants under the Beneficial Ownership Blocker, represent 9.99% of the outstanding shares of Common Stock (calculated in accordance with the footnote below). The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any. (3) Percent of class calculated based on the sum of (i) 47,903,215 shares of Common Stock outstanding on May 14, 2025, as disclosed in the Issuer's Definitive Proxy Statement for the 2025 Annual Meeting of the Stockholders filed on Schedule 14A with the SEC on May 21, 2025 (the "Proxy Statement"), (ii) 15,225,158 shares of Common Stock issued by the Issuer in the PIPE as reported by the Issuer in its Form 8-K dated August 5, 2025 filed with the SEC on August 6, 2025 (the "Form 8-K"), plus (iii) 726,435 shares of Common Stock issuable upon exercise of the Warrants directly held by the Redmile Funds, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of those Warrants.


SCHEDULE 13D




Comment for Type of Reporting Person:
(1) The source of funds was working capital of the Redmile Funds, including RBI II. (2) Jeremy C. Green's beneficial ownership of the Common Stock is comprised of 5,539,724 shares of Common Stock owned by RBI II and certain other Redmile Funds. In addition, Mr. Green may beneficially own 112,936 shares of Common Stock that are issuable upon the exercise of certain vested options. The stock options were granted to Mike Lee, a managing director of Redmile, in connection with his service as a member of the Board of Directors and may be exercised within 60 days of the date of this filing. Pursuant to the policies of Redmile, Mr. Lee holds the stock options as a nominee on behalf, and for the sole benefit, of Redmile and has assigned all economic, pecuniary and voting rights in respect of the stock options to Redmile. Subject to the Beneficial Ownership Blocker, Mr. Green may also be deemed to beneficially own 11,296,283 shares of Common Stock issuable upon exercise of the Warrants, including the Warrants purchased by RBI II and certain other Redmile Funds in the PIPE. Pursuant to the terms of the Warrants, the Issuer may not effect any exercise of the Warrants, and a holder of a Warrants may not exercise the Warrants held by such holder to the extent that the Beneficial Ownership Blocker applies. The Beneficial Ownership Limitation may be changed at a holder's election upon 61 days' notice to the Issuer. The 6,379,095 shares of Common Stock reported as beneficially owned by Mr. Green in this Schedule 13D, which includes 726,435 shares of Common Stock issuable upon exercise of certain of the Warrants under the Beneficial Ownership Blocker, represent 9.99% of the outstanding shares of Common Stock (calculated in accordance with the footnote below). The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any. (3) Percent of class calculated based on the sum of (i) 47,903,215 shares of Common Stock outstanding on May 14, 2025, as disclosed in the Proxy Statement, (ii) 15,225,158 shares of Common Stock issued by the Issuer in the PIPE as reported by the Form 8-K plus (iii) 726,435 shares of Common Stock issuable upon exercise of the Warrants directly held by the Redmile Funds, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of those Warrants.


SCHEDULE 13D




Comment for Type of Reporting Person:
(1) RBI II's beneficial ownership of the Common Stock is comprised of 3,338,997 shares of Common Stock. Subject to the Beneficial Ownership Blocker (as defined below), RBI II also beneficially owns 5,647,258 shares of Common Stock issuable upon exercise of certain Warrants, including the pre-funded warrants and common warrants purchased by RBI II in the PIPE. Pursuant to the terms of the Warrants, the Issuer may not effect any exercise of the Warrants, and a holder of a Warrants may not exercise the Warrants held by such holder to the extent that the Beneficial Ownership Blocker applies. The Beneficial Ownership Limitation may be changed at a holder's election upon 61 days' notice to the Issuer. The shares of Common Stock reported as beneficially owned by RBI II in this Schedule 13D represent the shares of Common Stock held directly by RBI II and the 726,435 shares of Common Stock that could be issued to RBI II upon exercise of certain of the Warrants directly held by RBI II under the Beneficial Ownership Blocker. (2) Percent of class calculated based on the sum of (i) 47,903,215 shares of Common Stock outstanding on May 14, 2025, as disclosed in the Proxy Statement, (ii) 15,225,158 shares of Common Stock issued by the Issuer in the PIPE as reported by the Form 8-K plus (iii) 726,435 shares of Common Stock issuable upon exercise of the Warrants directly held by RBI II, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of those Warrants.


SCHEDULE 13D


Redmile Group, LLC
Signature:/s/ Jeremy C. Green
Name/Title:Managing Member
Date:08/26/2025
Jeremy C. Green
Signature:/s/ Jeremy C. Green
Name/Title:Jeremy C. Green
Date:08/26/2025
Redmile Biopharma Investments II, L.P.
Signature:/s/ Jeremy C. Green
Name/Title:Managing Member of Redmile Group, LLC, the Managing Member of Redmile Biopharma Investments II (GP), LLC, its General Partner
Date:08/26/2025

FAQ

What stake does Redmile report in Shattuck Labs (STTK)?

Redmile Group and affiliated funds report beneficial ownership of 6,379,095 shares, representing 9.99% of the class on the filing's calculation basis.

How much did Redmile invest in the PIPE for STTK?

The Redmile Funds used approximately $3,555,190 in aggregate working capital to acquire Pre-Funded Warrants and Common Warrants; RBI II contributed about $1,777,211 of that total.

What types of securities did Redmile acquire in the PIPE?

Redmile acquired Pre-Funded Warrants and Common Warrants, together allowing purchase of up to 4,097,730 pre-funded shares and 4,097,730 common shares subject to the Beneficial Ownership Blocker.

Are there resale or registration rights for the warrants' underlying shares?

Yes. The filing discloses a Registration Rights Agreement under which the issuer will file to register resale of Common Stock issuable upon exercise, with a target filing no later than 30 calendar days after closing.

Did any board changes occur with the PIPE closing?

Yes. The filing states that Michael Lee resigned from the Issuer's Board of Directors concurrent with the PIPE closing and that the resignation was not due to disagreements regarding operations, policies or practices.
Shattuck Labs, Inc.

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