Filed Pursuant to Rule 424(b)(7)
Registration No. 333-279067
PROSPECTUS SUPPLEMENT
(To Prospectus dated May 9, 2024)
21,686,760 shares of Common Stock
Unless otherwise stated, all
references in this prospectus supplement to “we,” “us,” “our,” “Protara,” the “Company”
and similar designations refer to Protara Therapeutics, Inc.
This prospectus supplement
updates the prospectus dated May 9, 2024, relating to the resale, from time to time, by the selling stockholders identified in the prospectus,
or, the selling stockholders of up to 21,686,760 shares of our common stock, par value $0.001 per share, (“common stock”)
consisting of (i) 9,143,380 shares of common stock held by the selling stockholders (“Initial Shares”), (ii) 1,700,000 shares
of common stock (“Pre-Funded Warrant Shares”) issuable upon the exercise of pre-funded warrants held by certain of the selling
stockholders (“Pre-Funded Warrants”) and (iii) 10,843,380 shares of common stock (“Common Warrant Shares”) issuable
upon the exercise of warrants held by the selling stockholders (“Common Warrants”). The Initial Shares, Pre-Funded Warrant
Shares and Common Warrant Shares shall be collectively referred to as the “Securities” or the “Shares.”
Investing in our common
stock involves a high degree of risk. You should review carefully the risks and uncertainties described under the heading “Risk
Factors” on page 8 of the accompanying prospectus and any similar section contained in this prospectus supplement and any related
free writing prospectus, and under similar headings in the other documents that are incorporated by reference into this prospectus supplement
or the accompanying prospectus.
NEITHER THE SECURITIES
AND EXCHANGE COMMISSION NOR ANY STATE SECURITIES COMMISSION HAS APPROVED OR DISAPPROVED OF THESE SECURITIES OR DETERMINED IF THIS PROSPECTUS
SUPPLEMENT OR THE ACCOMPANYING PROSPECTUS ARE TRUTHFUL OR COMPLETE. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
The date of this prospectus supplement is January
30, 2026.
SELLING
STOCKHOLDERS
The following information supplements the information
set forth under the caption “Selling Stockholders” in the accompanying prospectus. This prospectus supplement includes information
with respect to selling stockholders not previously listed in the prospectus.
The following table sets forth information, as
of January 30, 2026, with respect to the selling stockholder named below, regarding the number of shares of common stock acquired, or
acquirable, by such selling stockholder as a result of an assignment on January 28, 2026 by OTA Trading Fund 1 LLC to Funicular Funds,
LP of Common Warrants exercisable for up to 142,400 Warrant Shares. Such information is based on information provided by or on behalf
of the selling stockholder and is accurate to the best of our knowledge as of January 30, 2026.
The number of shares in the column “Number
of Shares of Common Stock Owned As of the Date Hereof” represents the number of shares of common stock that are actually owned as
of the date of this prospectus supplement, and does not represent the number of shares that such selling stockholder may otherwise be
obligated to report as “beneficially owned” by such selling stockholder under other rules of the SEC. Please refer to the
section titled “Security Ownership of Certain Beneficial Owners and Management” in our Proxy Statement for our 2025 Annual
Meeting of Stockholders filed with the SEC on April 25, 2025 for information regarding beneficial ownership.
The table set forth under the caption “Selling
Stockholders” in the accompanying prospectus is hereby supplemented as follows:
| Name and Address | |
Number of Shares of Common Stock Owned As of the Date Hereof | | |
Number of Shares of Common Stock Offered Hereby | | |
Number of Shares of Common Stock Underlying Warrants Offered Hereby | | |
Number of Shares of Common Stock Owned After the Offering of All Common Stock Offered Hereby | | |
Percentage of Shares of Common Stock to be Owned by Selling Stockholder After the Offering of All Common Stock Offered Hereby | | |
Beneficial Ownership Limitation | |
Funicular Funds, LP(17) 601 California Street, Suite 1151 San Francisco, CA 94108 | |
| — | | |
| — | | |
| 142,400 | | |
| — | | |
| — | | |
| 4.99 | % |
| (17) |
Cable Car Capital, LP, as the General Partner of Funicular Funds, LP, and Jacob Ma-Weaver, as the Managing Member of Cable Car Capital, LP, may each be deemed to have voting or investment control over the Shares. |