[Form 4] Thermo Fisher Scientific, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Marc N. Casper, Chairman & CEO of Thermo Fisher Scientific (TMO), reported option exercise and market sales on 09/05/2025 under a Rule 10b5-1 plan. The filing shows the exercise or acquisition of 400 shares at an exercise/conversion price of $253.99 and three market dispositions of 200, 100 and 100 shares at $500, $501 and $501.01 respectively.

Beneficial ownership reported after the transactions is 113,762.285 shares. The report discloses indirect holdings of 11,300 shares by the Alison Casper 2020 Irrevocable Trust, 14,608 shares by Floral Park Associates, Inc., and 5,000 shares by MNC 2020 Irrevocable Trust. The transactions were effected pursuant to a 10b5-1 trading plan adopted April 28, 2025.

Positive

• Transactions executed under a Rule 10b5-1 plan, indicating preplanned trading and compliance with insider trading rules
• Maintained substantial beneficial ownership after the transactions: 113,762.285 shares reported
• Clear disclosure of indirect holdings by trusts and entities (Alison Casper 2020 Irrevocable Trust, Floral Park Associates, Inc., MNC 2020 Irrevocable Trust)

Negative

• Net decrease of 400 shares in reported beneficial ownership following the reported exercise and sales (from 114,162.285 to 113,762.285)
• Market dispositions at higher prices (sales at $500, $501, $501.01) reduced direct holdings

Insights

Securities Analyst

TL;DR: Routine insider activity—option exercise plus planned market sales under a 10b5-1 plan; modest net decrease in reported holdings.

The filing documents an option-related acquisition of 400 shares at $253.99 and three market sales totaling 400 shares at roughly $500–$501.01 on 09/05/2025. The transactions were executed under a Rule 10b5-1 plan adopted on April 28, 2025, indicating preplanned disposition rather than opportunistic trading. Reported beneficial ownership after the activity is 113,762.285 shares, including specified indirect holdings. From an investor-materiality standpoint, these are routine executive transactions and do not by themselves change control or signal a material shift in ownership.

Corporate Governance Expert

TL;DR: Governance signals consistent with compliance—use of 10b5-1 plan and attorney-in-fact signature are clear procedural safeguards.

The disclosure notes the 10b5-1 plan adoption date and includes an attorney-in-fact signature dated 09/09/2025, reflecting governance procedures for insider transactions. The filer also disclaims indirect beneficial ownership for certain trust-held shares except for pecuniary interests. These elements align with standard disclosure practice for executive stock exercises and planned sales.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

CASPER MARC N

(Last) (First) (Middle)

168 THIRD AVENUE

(Street)

WALTHAM MA 02451

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
THERMO FISHER SCIENTIFIC INC. [ TMO ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chairman & CEO

3. Date of Earliest Transaction (Month/Day/Year)
09/05/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	09/05/2025		M		400	A	$253.99	114,162.285	D
Common Stock	09/05/2025		S(1)		200	D	$500	113,962.285	D
Common Stock	09/05/2025		S(1)		100	D	$501	113,862.285	D
Common Stock	09/05/2025		S(1)		100	D	$501.01	113,762.285	D
Common Stock								11,300	I	By Alison Casper 2020 Irrevocable Trust(2)
Common Stock								14,608	I	By Floral Park Associates, Inc.
Common Stock								5,000	I	By MNC 2020 Irrevocable Trust(3)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to Buy)	$253.99	09/05/2025		M			400	(4)	02/26/2026	Common Stock	400	$0	24,354	D

Explanation of Responses:

1. The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on April 28, 2025.

2. The reporting person disclaims beneficial ownership of the securities reported herein as indirectly beneficially owned, except to the extent of any pecuniary interest therein.

3. The reporting person disclaims beneficial ownership of the securities reported herein as indirectly beneficially owned, except to the extent of any pecuniary interest therein.

4. The option vested in four equal installments on February 26, 2020, 2021, 2022, and 2023.

	/s/ Melodie T. Morin, Attorney-in-Fact for Marc N. Casper	09/09/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What transactions did Marc N. Casper report on Form 4 for TMO?

On 09/05/2025 he reported acquiring 400 shares at $253.99 and selling 200, 100 and 100 shares at $500, $501 and $501.01 respectively.

Were the transactions part of a trading plan?

Yes. The transactions were effected pursuant to a Rule 10b5-1 trading plan adopted April 28, 2025.

What is Marc Casper's reported beneficial ownership after these transactions?

The filing reports 113,762.285 shares beneficially owned following the transactions.

Are there indirect holdings disclosed in the Form 4?

Yes. The filing discloses 11,300 shares by the Alison Casper 2020 Irrevocable Trust, 14,608 shares by Floral Park Associates, Inc., and 5,000 shares by MNC 2020 Irrevocable Trust.

Who signed the Form 4 filing?

The form is signed by Melodie T. Morin as Attorney-in-Fact for Marc N. Casper, dated 09/09/2025.