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Trevi Therapeutics SEC Filings

TRVI NASDAQ

Welcome to our dedicated page for Trevi Therapeutics SEC filings (Ticker: TRVI), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Digging through Trevi Therapeutics’ dense biotech disclosures to find the next Haduvio milestone or dilution risk can feel like reading lab notes in a foreign language. Clinical-stage companies report reams of trial data, patent updates, and stock offering details—yet investors still need one clear answer: how does it affect TRVI’s value?

Stock Titan’s AI-powered analysis turns Trevi Therapeutics SEC filings into plain English. Whether you’re tracking a sudden 8-K material event explained, scanning the latest Trevi Therapeutics quarterly earnings report 10-Q filing, or comparing insider moves, our platform highlights what matters. Real-time alerts surface Trevi Therapeutics Form 4 insider transactions real-time, while concise summaries break down R&D spend, trial endpoints, and cash runway in the annual report—think Trevi Therapeutics annual report 10-K simplified rather than 200 pages of jargon.

Common questions are answered as you read: “Why did management sell shares?”—check the Trevi Therapeutics executive stock transactions Form 4. “Did the proxy reveal new stock-option grants?”—see the Trevi Therapeutics proxy statement executive compensation. Need quick context before a catalyst? Our dashboards pair AI text extraction with key metrics so understanding Trevi Therapeutics SEC documents with AI becomes part of your workflow. From Trevi Therapeutics insider trading Form 4 transactions to Trevi Therapeutics earnings report filing analysis, every disclosure is searchable, linked, and explained simply—saving hours and giving you the clarity to act before the market does.

Rhea-AI Summary

Royal Bank of Canada (RY) is marketing Capped Enhanced Return Buffer Notes linked to the EURO STOXX 50® Index (SX5E). The two-year notes are expected to price on 18 Jul 2025, settle on 23 Jul 2025 and mature on 22 Jul 2027. At maturity investors receive: (i) if the index closes above its initial level, 200 % of the positive index return, capped at a 23.25 % maximum gain; (ii) full principal return if the index is flat or down by up to 15 % (the buffer); (iii) a dollar-for-dollar loss beyond the 15 % downside buffer.

Key terms include a 15 % Buffer Percentage (Buffer Value = 85 % of the initial index level) and an initial estimated value of $917–$967 per $1,000 note, below the public offer price. The notes pay no periodic interest, are unsecured obligations of RBC and expose holders to the bank’s credit risk. Additional risk factors cited in the free-writing prospectus highlight limited secondary market liquidity, potential conflicts of interest in RBC Capital Markets’ calculation-agent role, uncertain U.S. tax treatment and the possibility of early acceleration upon a change-in-law event.

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FAQ

What is the current stock price of Trevi Therapeutics (TRVI)?

The current stock price of Trevi Therapeutics (TRVI) is $6.84 as of July 17, 2025.

What is the market cap of Trevi Therapeutics (TRVI)?

The market cap of Trevi Therapeutics (TRVI) is approximately 751.2M.

What is the primary focus of Trevi Therapeutics?

Trevi Therapeutics is focused on developing innovative therapies, notably Haduvio™, an oral nalbuphine ER formulation that targets chronic cough in conditions such as idiopathic pulmonary fibrosis and refractory chronic cough, as well as pruritic conditions.

How does Haduvio work?

Haduvio utilizes a dual mechanism by acting as a kappa-opioid receptor agonist and a mu-opioid receptor antagonist. This unique combination is designed to modulate the cough reflex arc and improve patient outcomes without the risks associated with traditional opioid therapies.

Which conditions are being targeted by Trevi Therapeutics?

The company targets chronic cough as seen in idiopathic pulmonary fibrosis and refractory chronic cough, along with pruritic dermatologic conditions such as prurigo nodularis.

What stage is Trevi Therapeutics currently in?

Trevi is in the clinical-stage of development and is actively conducting Phase 2a and Phase 2b clinical trials to evaluate the efficacy, safety, and optimal dosing regimens for Haduvio.

Why is Trevi's research significant in the current medical landscape?

Chronic cough, especially in IPF and RCC patients, remains an unmet medical need with few or no approved treatment options. Trevi's work with Haduvio offers a novel approach targeting the underlying mechanisms of cough hypersensitivity, potentially improving patient quality of life.

How does Trevi Therapeutics differentiate itself from competitors?

Trevi differentiates itself by focusing on a distinct dual mechanism of action in its therapy that addresses both central and peripheral pathways in the cough reflex arc. This strategic focus on unmet needs, combined with rigorous clinical trial methodologies, strengthens its position in the market.

Are there any specific safety concerns associated with Haduvio?

Clinical trials are carefully designed to evaluate safety, including the potential for abuse, while monitoring adverse events. So far, the safety profile of nalbuphine ER is consistent with its known characteristics, though detailed data continues to be gathered through ongoing studies.

What potential impact does Trevi Therapeutics have on patients?

By addressing chronic cough and pruritic conditions with a targeted, novel approach, Trevi Therapeutics has the potential to relieve debilitating symptoms and improve both the physical and psychological quality of life for patients who currently have limited treatment options.
Trevi Therapeutics

NASDAQ:TRVI

TRVI Rankings

TRVI Stock Data

751.23M
91.72M
0.94%
82.44%
4.24%
Biotechnology
Pharmaceutical Preparations
Link
United States
NEW HAVEN