[Form 4] Twist Bioscience Corporation Insider Trading Activity

Rhea-AI Filing Summary

Robert F. Werner, Chief Accounting Officer and director of Twist Bioscience Corp (TWST), reported a non-discretionary sale of 853 shares of common stock on 08/25/2025 at a price of $27.691 per share to satisfy tax withholding obligations related to vested restricted stock units. After the transaction, Mr. Werner beneficially owned 48,689 shares directly. The Form 4 was executed by an attorney-in-fact and dated 08/27/2025.

This filing indicates a routine "sell-to-cover" transaction mandated by the issuer to meet tax obligations on vesting and does not represent a voluntary market sale by the reporting person. The disclosure follows Section 16 reporting requirements and shows continued ownership of a material stake by the reporting officer.

Insights

Financial Analyst

TL;DR: Small mandated sell-to-cover reduces holdings slightly; routine reporting with no clear negative signal about company fundamentals.

The transaction is a non-discretionary sell-to-cover of 853 shares at $27.691 to satisfy tax withholding on vested RSUs. Such transactions are common when companies require withholding at vesting and typically do not reflect active insider selling for liquidity. With 48,689 shares remaining directly owned, the reporting officer retains exposure to the company's equity. From a financial perspective, this Form 4 is a compliance disclosure and does not provide actionable information about revenue, earnings, or changes to operational outlook.

Corporate Governance Expert

TL;DR: Filing shows compliance with reporting rules and an expected tax-withholding sale; governance practice appears standard.

The report identifies Mr. Werner as an officer and director and documents the issuer's election to perform a "sell-to-cover" to satisfy tax obligations on vested RSUs. The use of an attorney-in-fact to sign the Form 4 is permissible and the timely filing demonstrates adherence to Section 16 obligations. There is no indication of irregular governance actions or discretionary insider divestiture in this disclosure.

Insider Trade Summary

Net Seller: 853 shares ($23,620)

Net Sell 1 txn

Insider WERNER ROBERT F.

Role Chief Accounting Officer

Sold 853 shs ($24K)

Type	Security	Shares	Price	Value
Sale	Common Stock	853	$27.691	$24K

Holdings After Transaction: Common Stock — 48,689 shares (Direct)

Footnotes (1)

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Form 4 Insider Transactions: What Each Field Means →

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

WERNER ROBERT F.

(Last) (First) (Middle)

C/O TWIST BIOSCIENCE CORPORATION

681 GATEWAY BLVD

(Street)

SOUTH SAN FRANCISCO CA 94080

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Twist Bioscience Corp [ TWST ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Accounting Officer

3. Date of Earliest Transaction (Month/Day/Year)
08/25/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	08/25/2025		S		853(1)	D	$27.691	48,689	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Represents the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of a tax withholding obligation to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

Remarks:

	/s/ Kendra Fox, as Attorney-in-Fact for Robert F. Werner	08/27/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.