Artisan Partners Asset Management and affiliated entities amended a Schedule 13G to report beneficial ownership of 6,217,213 shares of Twist Bioscience Corporation common stock, representing 10.1% of the class based on 01/27/2026. The filing states these shares were acquired on behalf of discretionary clients of Artisan Partners Limited Partnership.
Positive
None.
Negative
None.
Insights
Large passive position reported: Artisan holds 6,217,213 shares (10.1%).
Artisan Partners and affiliated entities jointly report beneficial ownership of 6,217,213 shares, equal to 10.1% of outstanding common stock as of 01/27/2026. The position is held for discretionary clients of APLP.
Holding is reported under a joint filing agreement; cash‑flow beneficiaries are the underlying clients. Timing and planned disposition activity are not stated in the excerpt; future filings would disclose any material trading.
Filing clarifies voting and dispositive powers across related entities.
The schedule shows shared voting power 5,234,848 and shared dispositive power 6,217,213, reflecting the reporting structure among APAM, Artisan Holdings, Artisan Investments, and APLP. The comment clarifies the chain of control among the entities.
Beneficial ownership is attributed to discretionary clients; the filing notes no single client holds >5% economically. Monitor subsequent amendments for any change in voting or dispositive allocations.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 5)
Twist Bioscience Corporation
(Name of Issuer)
Common Stock
(Title of Class of Securities)
02/27/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
SCHEDULE 13G
CUSIP Number(s):
1
Names of Reporting Persons
Artisan Partners Asset Management Inc.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
5,234,848.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
6,217,213.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
6,217,213.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
10.1 %
12
Type of Reporting Person (See Instructions)
HC
Comment for Type of Reporting Person:
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.
SCHEDULE 13G
CUSIP Number(s):
1
Names of Reporting Persons
Artisan Partners Holdings LP
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
5,234,848.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
6,217,213.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
6,217,213.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
10.1 %
12
Type of Reporting Person (See Instructions)
HC
Comment for Type of Reporting Person:
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.
SCHEDULE 13G
CUSIP Number(s):
1
Names of Reporting Persons
Artisan Investments GP LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
5,234,848.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
6,217,213.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
6,217,213.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
10.1 %
12
Type of Reporting Person (See Instructions)
HC
Comment for Type of Reporting Person:
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.
SCHEDULE 13G
CUSIP Number(s):
1
Names of Reporting Persons
Artisan Partners Limited Partnership
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
5,234,848.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
6,217,213.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
6,217,213.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
10.1 %
12
Type of Reporting Person (See Instructions)
IA
Comment for Type of Reporting Person:
(e) Artisan Partners Limited Partnership is an investment adviser registered under section 203 of the Investment Advisers Act of 1940.
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.
Address or principal business office or, if none, residence:
APAM, Artisan Holdings, Artisan Investments, and APLP are all located at:
875 East Wisconsin Avenue, Suite 800
Milwaukee, WI 53202
(c)
Citizenship:
APAM is a Delaware corporation; Artisan Holdings is a Delaware limited partnership; Artisan Investments is a Delaware limited liability company; APLP is a Delaware limited partnership
(d)
Title of class of securities:
Common Stock
(e)
CUSIP No.:
90184D100
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
6,217,213
(b)
Percent of class:
10.1% (based on 61,311,704 shares outstanding as of 01/27/2026)
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
None
(ii) Shared power to vote or to direct the vote:
5,234,848
(iii) Sole power to dispose or to direct the disposition of:
None
(iv) Shared power to dispose or to direct the disposition of:
6,217,213
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.
The shares reported herein have been acquired on behalf of discretionary clients of APLP. Persons other than APLP are entitled to receive all dividends from, and proceeds from the sale of, those shares. None of those persons, to the knowledge of APAM, Artisan Holdings, Artisan Investments, or APLP has an economic interest in more than 5% of the class.
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Artisan Partners Asset Management Inc.
Signature:
/s/ Gregory K. Ramirez
Name/Title:
Gregory K. Ramirez, Executive Vice President of Artisan Partners Asset Management Inc.
Date:
03/06/2026
Artisan Partners Holdings LP
Signature:
/s/ Gregory K. Ramirez
Name/Title:
Gregory K. Ramirez, Executive Vice President of Artisan Partners Asset Management Inc., as the general partner of Artisan Partners Holdings LP
Date:
03/06/2026
Artisan Investments GP LLC
Signature:
/s/ Gregory K. Ramirez
Name/Title:
Gregory K. Ramirez, Vice President of Artisan Investments GP LLC
Date:
03/06/2026
Artisan Partners Limited Partnership
Signature:
/s/ Gregory K. Ramirez
Name/Title:
Gregory K. Ramirez, Vice President of Artisan Investments GP LLC, as the general partner of Artisan Partners Limited Partnership
Date:
03/06/2026
Exhibit Information
Exhibit Index
Exhibit 1 - Joint Filing Agreement dated 3/6/2026 by and among Artisan Partners Asset Management Inc., Artisan Partners Holdings LP, Artisan Investments GP LLC, and Artisan Partners Limited Partnership.
Artisan Partners reports beneficial ownership of 6,217,213 shares, representing 10.1% of Twist Bioscience's common stock based on 01/27/2026. The position is held for discretionary clients of Artisan Partners Limited Partnership.
Who are the filing parties in the TWST 13G/A?
The filing is a joint report by Artisan Partners Asset Management Inc., Artisan Partners Holdings LP, Artisan Investments GP LLC, and Artisan Partners Limited Partnership, reflecting their roles in managing the disclosed position.
How much voting power does Artisan report for TWST?
The report lists shared voting power of 5,234,848 shares and shared dispositive power of 6,217,213. No sole voting or sole dispositive power is claimed in the filing excerpt.
Are the shares owned directly by Artisan or clients?
The filing states the shares were acquired on behalf of discretionary clients of Artisan Partners Limited Partnership. Underlying clients, not Artisan, are entitled to dividends and sale proceeds.
What baseline share count did the filing use to compute the percentage?
The percentage uses an outstanding share count of 61,311,704 shares as of 01/27/2026, which yields the reported 10.1% ownership figure.
