ARK and Catherine Wood report 12.36% Twist Bioscience (TWST) ownership

Rhea-AI Filing Summary

Twist Bioscience Corp reported a significant shareholder update as of December 31, 2025. ARK Investment Management LLC and its founder Catherine D. Wood together beneficially own 7,559,495 shares of Twist common stock, representing 12.36% of the outstanding class.

ARK holds sole voting power over 7,091,113 shares and sole dispositive power over all 7,559,495 shares. Catherine Wood has shared voting power over 7,227,245 shares and shared dispositive power over 7,559,495 shares, reflecting her control role at ARK.

The filing states that these securities were acquired and are held in the ordinary course of business, without the purpose or effect of changing or influencing control of Twist Bioscience, and not in connection with any control-related transaction. ARK also notes that its client ARK Innovation ETF has an interest in more than 5% of the reported securities.

Insights

Institutional ownership analyst

ARK and Catherine Wood report a 12.36% passive stake in Twist Bioscience.

ARK Investment Management and Catherine D. Wood disclose beneficial ownership of 7,559,495 Twist Bioscience common shares, or 12.36% of the class as of December 31, 2025. ARK has sole voting power over 7,091,113 shares and sole dispositive power over all reported shares.

The certification explicitly states the position is held in the ordinary course of business and not for the purpose or effect of changing or influencing control of Twist. This aligns with a passive institutional holding under a Schedule 13G framework rather than an activist stance.

One ARK client, ARK Innovation ETF, is identified as having an interest exceeding 5% of the reported securities, underscoring concentration within ARK-managed vehicles. Future ownership updates in amendments will show whether ARK’s percentage stake grows or declines relative to this December 31, 2025 baseline.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 7)

Twist Bioscience Corp

(Name of Issuer)

Common Stock

(Title of Class of Securities)

90184D100

(CUSIP Number)

12/31/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. 90184D100

1

Names of Reporting Persons

ARK Investment Management LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 7,091,113.00
6	Shared Voting Power 136,132.00
7	Sole Dispositive Power 7,559,495.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

7,559,495.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

12.36 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

CUSIP No. 90184D100

1

Names of Reporting Persons

Catherine D. Wood

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 7,227,245.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 7,559,495.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

7,559,495.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

12.36 %

12

Type of Reporting Person (See Instructions)

HC, IN

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Twist Bioscience Corp
(b)	Address of issuer's principal executive offices: 681 Gateway Blvd, South San Francisco, CA, 94080
Item 2.
(a)	Name of person filing: (i) ARK Investment Management LLC ("ARK") (ii) Catherine D. Wood
(b)	Address or principal business office or, if none, residence: ARK and Catherine D. Wood: 200 Central Avenue, St. Petersburg, FL 33701
(c)	Citizenship: (i) ARK: Delaware (ii) Catherine D. Wood: United States
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 90184D100
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: ARK and Catherine D. Wood: 7,559,495
(b)	Percent of class: ARK and Catherine D. Wood: 12.36
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: (i) ARK: 7,091,113 (ii) Catherine D. Wood: 0
	(ii) Shared power to vote or to direct the vote: (i) ARK: 136,132 (ii) Catherine D. Wood: 7,227,245
	(iii) Sole power to dispose or to direct the disposition of: (i) ARK: 7,559,495 (ii) Catherine D. Wood: 0
	(iv) Shared power to dispose or to direct the disposition of: (i) ARK: 0 (ii) Catherine D. Wood: 7,559,495
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. No client of ARK Investment Management LLC currently has an interest in the securities reported herein in excess of 5 percent except ARK Innovation ETF, a series of a Delaware statutory trust.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

ARK Investment Management LLC

Signature:	/s/ Kellen Carter
Name/Title:	Kellen Carter, Chief Compliance Officer
Date:	02/03/2026

Catherine D. Wood

Signature:	/s/ Catherine D. Wood
Name/Title:	Catherine D. Wood, Chief Executive Officer, Chief Investment Officer
Date:	02/03/2026

FAQ

How many Twist Bioscience (TWST) shares does ARK Investment Management beneficially own?

ARK Investment Management LLC and Catherine D. Wood beneficially own 7,559,495 Twist Bioscience common shares. This position represents 12.36% of the company’s outstanding common stock as of December 31, 2025, based on the ownership details disclosed in the Schedule 13G/A amendment.

What percentage of Twist Bioscience’s stock is owned by ARK and Catherine Wood?

ARK Investment Management LLC and Catherine D. Wood together report beneficial ownership of 12.36% of Twist Bioscience’s common stock. This percentage is based on their holding of 7,559,495 shares as of December 31, 2025, as detailed in the ownership section of the filing.

Does ARK Investment Management have control intentions over Twist Bioscience (TWST)?

The certification states the Twist Bioscience securities were acquired and are held in the ordinary course of business and not for the purpose or effect of changing or influencing control. It also notes they are not held in connection with any transaction having that control-related purpose or effect.

How are voting and dispositive powers over Twist Bioscience shares allocated between ARK and Catherine Wood?

ARK has sole voting power over 7,091,113 shares and sole dispositive power over 7,559,495 shares. Catherine D. Wood has shared voting power over 7,227,245 shares and shared dispositive power over 7,559,495 shares, reflecting her leadership role at ARK Investment Management.

Which ARK client has more than 5% interest in Twist Bioscience securities?

The filing notes that no ARK client has an interest over 5% of the class except ARK Innovation ETF, a series of a Delaware statutory trust. This ETF is identified as having an interest exceeding 5% in the Twist Bioscience securities reported by ARK Investment Management.

What type of securities does ARK hold in Twist Bioscience and what is the CUSIP?

ARK and Catherine D. Wood report holdings in Twist Bioscience Common Stock. The securities are identified with CUSIP number 90184D100. All ownership statistics in the filing, including share count and percentage, relate specifically to this class of common stock.