Twist Bioscience (TWST) stake of 3.5% reported by William Blair Investment Management

Rhea-AI Filing Summary

William Blair Investment Management, LLC reported its beneficial ownership position in Twist Bioscience Corp common stock. The firm reported beneficial ownership of 2,174,594 shares, representing 3.5% of the outstanding common stock. It has sole voting power over 1,975,454 shares and sole dispositive power over all 2,174,594 shares, with no shared voting or dispositive power. The filing indicates that the holder now owns 5 percent or less of the class of Twist Bioscience common stock. The reporting person is organized in Delaware and signed the report through its Chief Compliance Officer, Telmo Martins.

Key Figures

Beneficial ownership: 2,174,594 shares Percent of class: 3.5% Sole voting power: 1,975,454 shares +3 more

6 metrics

Beneficial ownership 2,174,594 shares Shares of Twist Bioscience common stock beneficially owned by William Blair Investment Management

Percent of class 3.5% Percentage of Twist Bioscience common stock class beneficially owned

Sole voting power 1,975,454 shares Number of shares over which William Blair Investment Management has sole power to vote

Sole dispositive power 2,174,594 shares Number of shares over which William Blair Investment Management has sole power to dispose

CUSIP 90184D100 CUSIP number for Twist Bioscience Corp common stock

Certification date 08/11/2026 Date the ownership report was signed by the Chief Compliance Officer

Key Terms

beneficially owned, sole voting power, sole dispositive power, percent of class, +1 more

5 terms

beneficially owned financial

"Amount beneficially owned: 2,174,594 (b) Percent of class: 3.5%"

Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.

sole voting power financial

"Sole power to vote or to direct the vote: 1,975,454"

Sole voting power is the exclusive right to cast votes attached to a shareholder’s stock without needing approval from anyone else. Like holding the only remote control for a TV, it lets that holder decide corporate matters such as board members, mergers, and policy changes, making it important to investors because it concentrates control and can strongly influence a company’s strategy and the value of its shares.

sole dispositive power financial

"Sole power to dispose or to direct the disposition of: 2,174,594"

Sole dispositive power is the exclusive legal authority to decide what happens to a security — for example, whether to sell, transfer, or retain shares — without needing anyone else’s permission. Investors care because it signals who truly controls the economic outcome of an investment: like holding the only key to a safe, the holder can realize gains or losses and may trigger regulatory reporting, insider rules, or influence over corporate ownership.

percent of class financial

"Percent of class: 3.5%"

Percent of class is the portion of a specific category of securities—such as a company’s common shares, preferred shares, or a bond series—that takes part in or approves a corporate action (vote, consent, tender, etc.). Investors watch this number because it reveals how much support or opposition exists within that particular shareholder group; like counting how many members of a club back a proposal, it can determine whether a plan passes or how influence is distributed.

Schedule 13G/A regulatory

"Form type: SCHEDULE 13G/A"

A Schedule 13G/A is an amended public filing with the U.S. securities regulator that updates a previous Schedule 13G, disclosing when an individual or group holds a substantial (typically over 5%) stake in a company and is claiming a passive, non‑controlling intent. Investors monitor these updates because rising or falling holdings can signal changing confidence, potential future moves, or shifts in voting power — like watching a public ledger where large shareholders quietly adjust their positions.

FAQ

What percentage of Twist Bioscience Corp (TWST) shares does William Blair Investment Management own?

William Blair Investment Management reports beneficial ownership of 3.5% of Twist Bioscience Corp common stock, representing 2,174,594 shares, according to the Schedule 13G/A filing signed by its Chief Compliance Officer on August 11, 2026.

How many Twist Bioscience (TWST) shares does William Blair Investment Management have voting power over?

William Blair Investment Management has sole voting power over 1,975,454 Twist Bioscience common shares and no shared voting power, as disclosed in the Schedule 13G/A ownership breakdown section.

What is the total number of Twist Bioscience (TWST) shares beneficially owned by William Blair Investment Management?

The filing states that William Blair Investment Management beneficially owns 2,174,594 shares of Twist Bioscience common stock, all subject to sole dispositive power and no shared dispositive power over any shares.

Is William Blair Investment Management a 5% or greater shareholder of Twist Bioscience (TWST)?

No. The Schedule 13G/A explicitly classifies William Blair Investment Management as having ownership of 5 percent or less of Twist Bioscience’s common stock, with its reported stake at 3.5% of the class.

Who signed the Twist Bioscience (TWST) ownership report for William Blair Investment Management?

The Schedule 13G/A for Twist Bioscience was signed by Telmo Martins, Chief Compliance Officer of William Blair Investment Management, LLC, dated August 11, 2026, certifying the reported ownership information.

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Available on EDGAR 08/11/2026 - 09:17 PM Accepted by SEC EDGAR 08/11/2026 - 09:16 PM Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 3)

Twist Bioscience Corp

(Name of Issuer)

Common Stock

(Title of Class of Securities)

90184D100

(CUSIP Number)

06/30/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 90184D100

1

Names of Reporting Persons

WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 1,975,454.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 2,174,594.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,174,594.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

3.5 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Twist Bioscience Corp
(b)	Address of issuer's principal executive offices: 681 GATEWAY BLVD., 681 GATEWAY BLVD., SOUTH SAN FRANCISCO, CALIFORNIA, 94080.
Item 2.
(a)	Name of person filing: William Blair Investment Management, LLC
(b)	Address or principal business office or, if none, residence: 150 North Riverside Plaza, Chicago, IL 60606
(c)	Citizenship: Delaware
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 90184D100
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 2,174,594
(b)	Percent of class: 3.5%
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 1,975,454
	(ii) Shared power to vote or to direct the vote: 0
	(iii) Sole power to dispose or to direct the disposition of: 2,174,594
	(iv) Shared power to dispose or to direct the disposition of: 0
Item 5.	Ownership of 5 Percent or Less of a Class.
	Ownership of 5 percent or less of a class
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC

Signature:	Telmo Martins
Name/Title:	Chief Compliance Officer
Date:	08/11/2026