Twist Bioscience Corporation disclosed that investment manager Artisan Partners and related entities filed an amended Schedule 13G reporting a sizable passive stake. The group reports beneficial ownership of 5,830,205 shares of Twist common stock, or 9.5% of the class, based on 61,273,653 shares outstanding as of 12/26/2025.
Artisan entities report no sole voting or dispositive power. They share voting power over 4,959,392 shares and share dispositive power over 5,830,205 shares, held on behalf of discretionary clients of Artisan Partners Limited Partnership. The filing states the position is held in the ordinary course of business and not for the purpose of changing or influencing control of Twist Bioscience.
Positive
None.
Negative
None.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 4)
Twist Bioscience Corporation
(Name of Issuer)
Common stock
(Title of Class of Securities)
90184D100
(CUSIP Number)
12/31/2025
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
SCHEDULE 13G
CUSIP No.
90184D100
1
Names of Reporting Persons
Artisan Partners Asset Management Inc.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
4,959,392.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
5,830,205.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
5,830,205.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.5 %
12
Type of Reporting Person (See Instructions)
HC
Comment for Type of Reporting Person:
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.
SCHEDULE 13G
CUSIP No.
90184D100
1
Names of Reporting Persons
Artisan Partners Holdings LP
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
4,959,392.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
5,830,205.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
5,830,205.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.5 %
12
Type of Reporting Person (See Instructions)
HC
Comment for Type of Reporting Person:
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.
SCHEDULE 13G
CUSIP No.
90184D100
1
Names of Reporting Persons
Artisan Investments GP LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
4,959,392.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
5,830,205.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
5,830,205.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.5 %
12
Type of Reporting Person (See Instructions)
HC
Comment for Type of Reporting Person:
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.
SCHEDULE 13G
CUSIP No.
90184D100
1
Names of Reporting Persons
Artisan Partners Limited Partnership
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
4,959,392.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
5,830,205.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
5,830,205.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.5 %
12
Type of Reporting Person (See Instructions)
IA
Comment for Type of Reporting Person:
(e) Artisan Partners Limited Partnership is an investment adviser registered under section 203 of the Investment Advisers Act of 1940.
(g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.
Address or principal business office or, if none, residence:
APAM, Artisan Holdings, Artisan Investments, and APLP are all located at:
875 East Wisconsin Avenue, Suite 800
Milwaukee, WI 53202
(c)
Citizenship:
APAM is a Delaware corporation; Artisan Holdings is a Delaware limited partnership; Artisan Investments is a Delaware limited liability company; APLP is a Delaware limited partnership
(d)
Title of class of securities:
Common stock
(e)
CUSIP No.:
90184D100
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
5,830,205
(b)
Percent of class:
9.5% (based on 61,273,653 shares outstanding as of 12/26/2025)
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
None
(ii) Shared power to vote or to direct the vote:
4,959,392
(iii) Sole power to dispose or to direct the disposition of:
None
(iv) Shared power to dispose or to direct the disposition of:
5,830,205
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.
The shares reported herein have been acquired on behalf of discretionary clients of APLP. Persons other than APLP are entitled to receive all dividends from, and proceeds from the sale of, those shares. None of those persons, to the knowledge of APAM, Artisan Holdings, Artisan Investments, or APLP has an economic interest in more than 5% of the class.
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Artisan Partners Asset Management Inc.
Signature:
/s/ Gregory K. Ramirez
Name/Title:
Gregory K. Ramirez, Executive Vice President of Artisan Partners Asset Management Inc.
Date:
02/03/2026
Artisan Partners Holdings LP
Signature:
/s/ Gregory K. Ramirez
Name/Title:
Gregory K. Ramirez, Executive Vice President of Artisan Partners Asset Management Inc., as the general partner of Artisan Partners Holdings LP
Date:
02/03/2026
Artisan Investments GP LLC
Signature:
/s/ Gregory K. Ramirez
Name/Title:
Gregory K. Ramirez, Vice President of Artisan Investments GP LLC
Date:
02/03/2026
Artisan Partners Limited Partnership
Signature:
/s/ Gregory K. Ramirez
Name/Title:
Gregory K. Ramirez, Vice President of Artisan Investments GP LLC, as the general partner of Artisan Partners Limited Partnership
Date:
02/03/2026
Comments accompanying signature:
Exhibit Index
Exhibit 1 - Joint Filing Agreement dated 2/3/2026 by and among Artisan Partners Asset Management Inc., Artisan Partners Holdings LP, Artisan Investments GP LLC, and Artisan Partners Limited Partnership.
What does the Twist Bioscience (TWST) Schedule 13G/A filed by Artisan Partners report?
The Schedule 13G/A shows Artisan-related entities reporting a passive ownership stake in Twist Bioscience. They beneficially own 5,830,205 common shares, representing 9.5% of the company’s outstanding stock, held for discretionary clients of Artisan Partners Limited Partnership.
How many Twist Bioscience (TWST) shares does Artisan Partners beneficially own and what percentage is this?
Artisan-related entities report beneficial ownership of 5,830,205 Twist Bioscience shares, equal to 9.5% of the common stock. This percentage is calculated using 61,273,653 shares outstanding as of December 26, 2025, as stated in the filing.
What voting and dispositive powers do Artisan entities have over Twist Bioscience (TWST) shares?
The filing states Artisan entities have no sole voting or dispositive power. They hold shared voting power over 4,959,392 shares and shared dispositive power over 5,830,205 shares, reflecting their role managing assets for discretionary clients.
Is Artisan Partners’ ownership in Twist Bioscience (TWST) intended to influence control of the company?
The certification states the Twist Bioscience shares were acquired and are held in the ordinary course of business. It further states they were not acquired for the purpose of changing or influencing control of Twist Bioscience.
On whose behalf are Artisan Partners’ Twist Bioscience (TWST) shares held and who receives dividends?
The filing explains the reported Twist shares were acquired on behalf of discretionary clients of Artisan Partners Limited Partnership. Persons other than APLP are entitled to receive all dividends and sale proceeds, and none is known to own over 5% of the class.
Which Artisan-related entities are listed as reporting persons for Twist Bioscience (TWST)?
The Schedule 13G/A lists Artisan Partners Asset Management Inc., Artisan Partners Holdings LP, Artisan Investments GP LLC, and Artisan Partners Limited Partnership as reporting persons, all organized in Delaware and connected through a stated general partner and holding-company structure.
