[SCHEDULE 13G/A] Twist Bioscience Corporation SEC Filing

Rhea-AI Filing Summary

Artisan Partners and several affiliated entities report beneficial ownership of 5,061,033 shares of Twist Bioscience common stock, equal to 8.4% of the outstanding class based on 59,916,141 shares outstanding as of 05/01/2025. The filing shows shared voting power of 4,078,039 shares and no sole voting or dispositive power reported.

The shares were acquired for and are held on behalf of discretionary clients of Artisan Partners Limited Partnership. The filing includes a certification that the holdings are held in the ordinary course of business and were not acquired to change or influence control of the issuer. No other person is reported to have an economic interest above 5% in these shares.

Positive

• Material institutional ownership: Artisan Partners and affiliates beneficially own 5,061,033 shares, representing 8.4% of TWST, signaling notable investor interest
• Passive profile certified: Filing states holdings are in the ordinary course of business and not intended to change or influence control

Negative

• None.

Insights

Financial Analyst

TL;DR: Artisan Partners holds an 8.4% beneficial stake (5.06M shares) in TWST with shared voting influence but no sole control.

Artisan Partners and affiliated entities disclose a material passive position representing 8.4% of Twist Bioscience. The structure shows shared voting power (4,078,039) and shared dispositive power equal to the full position, indicating portfolio-level control rather than concentrated director-level control. Because the filing is made under Schedule 13G and includes a certification of ordinary-course holdings, this appears to be a disclosure of institutional investment rather than an activist stake. The position size is large enough to attract investor attention but does not, on its face, signal a change in corporate control.

Corporate Governance Expert

TL;DR: Disclosure signals significant institutional ownership but no asserted intent to influence corporate control.

The filing identifies Artisan Partners and related entities as collective reporting persons with 5,061,033 shares beneficially owned and 4,078,039 shares of shared voting power. The submission clarifies holdings are for discretionary clients and states they were not acquired to change or influence control, consistent with a passive 13G profile. From a governance perspective, the lack of sole voting power and the ordinary-course certification reduce immediate regulatory or takeover implications, though an 8.4% stake is large enough to warrant monitoring of future filings for any shift in intent or governance engagement.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 2)

Twist Bioscience Corporation

(Name of Issuer)

Common Stock

(Title of Class of Securities)

90184D100

(CUSIP Number)

06/30/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. 90184D100

1

Names of Reporting Persons

Artisan Partners Asset Management Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 4,078,039.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 5,061,033.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

5,061,033.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.4 %

12

Type of Reporting Person (See Instructions)

HC

Comment for Type of Reporting Person: (g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.

SCHEDULE 13G

CUSIP No. 90184D100

1

Names of Reporting Persons

Artisan Partners Holdings LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 4,078,039.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 5,061,033.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

5,061,033.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.4 %

12

Type of Reporting Person (See Instructions)

HC

Comment for Type of Reporting Person: (g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.

SCHEDULE 13G

CUSIP No. 90184D100

1

Names of Reporting Persons

Artisan Investments GP LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 4,078,039.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 5,061,033.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

5,061,033.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.4 %

12

Type of Reporting Person (See Instructions)

HC

Comment for Type of Reporting Person: (g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.

SCHEDULE 13G

CUSIP No. 90184D100

1

Names of Reporting Persons

Artisan Partners Limited Partnership

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 4,078,039.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 5,061,033.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

5,061,033.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.4 %

12

Type of Reporting Person (See Instructions)

IA

Comment for Type of Reporting Person: (e) Artisan Partners Limited Partnership is an investment adviser registered under section 203 of the Investment Advisers Act of 1940. (g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Twist Bioscience Corporation
(b)	Address of issuer's principal executive offices: 681 Gateway Blvd, South San Francisco, CA 94080
Item 2.
(a)	Name of person filing: Artisan Partners Asset Management Inc. ("APAM") Artisan Partners Holdings LP ("Artisan Holdings") Artisan Investments GP LLC ("Artisan Investments") Artisan Partners Limited Partnership ("APLP")
(b)	Address or principal business office or, if none, residence: APAM, Artisan Holdings, Artisan Investments, and APLP are all located at: 875 East Wisconsin Avenue, Suite 800 Milwaukee, WI 53202
(c)	Citizenship: APAM is a Delaware corporation; Artisan Holdings is a Delaware limited partnership; Artisan Investments is a Delaware limited liability company; APLP is a Delaware limited partnership
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 90184D100
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 5,061,033
(b)	Percent of class: 8.4% (based on 59,916,141 shares outstanding as of 05/01/2025)
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 0
	(ii) Shared power to vote or to direct the vote: 4,078,039
	(iii) Sole power to dispose or to direct the disposition of: 0
	(iv) Shared power to dispose or to direct the disposition of: 5,061,033
Item 5.	Ownership of 5 Percent or Less of a Class.
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. The shares reported herein have been acquired on behalf of discretionary clients of APLP. Persons other than APLP are entitled to receive all dividends from, and proceeds from the sale of, those shares. None of those persons, to the knowledge of APAM, Artisan Holdings, Artisan Investments, or APLP has an economic interest in more than 5% of the class.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Artisan Partners Asset Management Inc.

Signature:	/s/ Gregory K. Ramirez
Name/Title:	Gregory K. Ramirez, Executive Vice President of Artisan Partners Asset Management Inc.
Date:	08/12/2025

Artisan Partners Holdings LP

Signature:	/s/ Gregory K. Ramirez
Name/Title:	Gregory K. Ramirez, Executive Vice President of Artisan Partners Asset Management Inc., as the general partner of Artisan Partners Holdings LP
Date:	08/12/2025

Artisan Investments GP LLC

Signature:	/s/ Gregory K. Ramirez
Name/Title:	Gregory K. Ramirez, Vice President of Artisan Investments GP LLC
Date:	08/12/2025

Artisan Partners Limited Partnership

Signature:	/s/ Gregory K. Ramirez
Name/Title:	Gregory K. Ramirez, Vice President of Artisan Investments GP LLC, as the general partner of Artisan Partners Limited Partnership
Date:	08/12/2025

Comments accompanying signature: Exhibit Index Exhibit 1 - Joint Filing Agreement dated 08/12/2025 by and among Artisan Partners Asset Management Inc., Artisan Partners Holdings LP, Artisan Investments GP LLC, and Artisan Partners Limited Partnership.

FAQ

How many TWST shares does Artisan Partners beneficially own?

Artisan Partners and affiliated filers report beneficial ownership of 5,061,033 shares of TWST.

What percentage of TWST does Artisan Partners own?

The reported position represents 8.4% of Twist Bioscience's common stock based on 59,916,141 shares outstanding as of 05/01/2025.

Does Artisan Partners have sole voting power over the TWST shares?

No. The filing shows 0 shares of sole voting power and 4,078,039 shares of shared voting power.

Are the TWST shares held for clients or the filing persons themselves?

The shares were acquired on behalf of discretionary clients of Artisan Partners Limited Partnership; other persons may receive dividends or sale proceeds.

Was the stake acquired to influence control of Twist Bioscience?

The filing includes a certification that the securities were acquired and are held in the ordinary course of business and were not acquired to change or influence control.