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Tyra Biosciences, Inc. SEC Filings

TYRA NASDAQ

Welcome to our dedicated page for Tyra Biosciences SEC filings (Ticker: TYRA), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Tyra Biosciences’ 10-K can stretch beyond 200 pages of R&D detail, clinical-trial tables, and complex royalty clauses—daunting for even seasoned biotech investors. If you came here looking for Tyra Biosciences insider trading Form 4 transactions or need the Tyra Biosciences quarterly earnings report 10-Q filing, you already know the challenge: crucial data is scattered across multiple forms, each released at different times.

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The platform covers every disclosure type investors track: the Tyra Biosciences annual report 10-K simplified highlights clinical risks; 10-Qs map quarter-over-quarter cash burn; 8-Ks flag trial read-outs, giving you Tyra Biosciences 8-K material events explained minutes after filing. Looking for governance details? Access the full Tyra Biosciences proxy statement executive compensation. Want to monitor management confidence? Drill into Tyra Biosciences executive stock transactions Form 4. From S-3 shelf registrations that hint at future capital raises to Section 16 filings that reveal insider sentiment, Stock Titan provides the complete picture—updated continuously and distilled into clear, actionable insights.

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iShares BB Rated Corporate Bond ETF, a series of iShares Trust, filed its routine Form NPORT-P for the monthly period ended 30-Apr-2025.

The fund reported total assets of $286.0 million, liabilities of $81.6 million, and net assets of $204.4 million. No borrowings were outstanding and no controlled foreign corporations were used. Cash and cash equivalents not otherwise disclosed totaled $0.20 million.

Interest-rate DV01 exposure in U.S. dollars was modest, led by the 5-year bucket at $26.96 thousand; a 100-bp parallel shift (DV100) would change portfolio value by $5.17 million in the 5-year tenor. Credit-spread sensitivity shows the portfolio is predominately non-investment-grade, with a 5-year CS01 of $55.35 thousand.

The fund is active in securities lending: across 20 counterparties, securities on loan totaled roughly $38.8 million (≈19% of net assets). Largest borrowers include Barclays Bank plc (~$9.0 m), BNP Paribas Prime Brokerage (~$7.25 m) and RBC Capital Markets (~$6.30 m). The filing indicates that some counterparties provided non-cash collateral, though exact amounts were not disclosed.

No preferred stock is outstanding, and the filing does not indicate that this will be the fund’s final NPORT-P submission.

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Tyra Biosciences, Inc. (TYRA) – Form 4 insider transaction

Director Gilla Kaplan filed a Form 4 disclosing two open-market sales of the company’s common stock.

  • 06/17/2025: Sold 10 shares at $10.35 each.
  • 06/18/2025: Sold 9,568 shares at a $9.7822 weighted-average price (individual trades ranged from $9.55 to $9.93).

After these transactions, Kaplan’s direct beneficial ownership stands at 28,231 shares. No derivative securities were involved, and the filing does not reference any 10b5-1 trading plan. The document was signed by Attorney-in-Fact Ali D. Fawaz on 06/20/2025.

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FAQ

What is the current stock price of Tyra Biosciences (TYRA)?

The current stock price of Tyra Biosciences (TYRA) is $10.05 as of July 2, 2025.

What is the market cap of Tyra Biosciences (TYRA)?

The market cap of Tyra Biosciences (TYRA) is approximately 512.1M.

What is the core focus of Tyra Biosciences?

Tyra Biosciences is focused on developing next-generation precision medicines targeting aberrations in FGFR biology. It primarily addresses unmet needs in oncology and rare skeletal dysplasias.

How does the SNÅP platform contribute to the company’s drug development?

The SNÅP platform enables rapid and precise drug design by using iterative molecular snapshots to predict genetic alterations. This facilitates the creation of highly selective therapies with potentially improved tolerability.

What is TYRA-300 and in which indications is it being evaluated?

TYRA-300 is an investigational, oral, FGFR3-selective inhibitor developed for the treatment of cancer and skeletal dysplasias. It is currently being evaluated in clinical studies for advanced urothelial carcinoma and conditions such as achondroplasia and hypochondroplasia.

How does Tyra Biosciences address the issue of acquired resistance in cancer therapies?

By leveraging its SNÅP platform, the company designs precision medicines that specifically target genetic mutations responsible for acquired resistance. This focused approach aims to enhance the efficacy and safety profile of its treatments compared to broader-acting therapies.

What sets Tyra Biosciences apart from other biotechnology companies?

The company distinguishes itself through its proprietary SNÅP platform and a focused development program targeting FGFR-mediated diseases. This specialized approach enables the design of highly selective drugs that aim to reduce on-target toxicities and overcome resistance challenges.

What are the strategic benefits of developing therapies for both oncology and skeletal dysplasias?

Targeting both oncology and skeletal dysplasias allows Tyra Biosciences to address significant unmet medical needs across diverse patient populations. This dual focus leverages common genetic targets and maximizes the utility of its precision medicine platform.

How does Tyra Biosciences ensure the durability and relevance of its clinical programs?

The company designs its clinical programs with a long-term perspective, emphasizing iterative drug development and precise targeting of genetic alterations. This approach, coupled with comprehensive preclinical and clinical evaluation, ensures the information remains evergreen and relevant.

What common challenges in drug development does Tyra Biosciences aim to overcome?

Tyra Biosciences aims to overcome challenges such as acquired resistance to existing therapies and the toxicities associated with pan-FGFR inhibitors. Their approach focuses on developing selective therapies that enhance treatment tolerability and efficacy.
Tyra Biosciences, Inc.

NASDAQ:TYRA

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512.10M
49.53M
4.64%
100.46%
8.06%
Biotechnology
Pharmaceutical Preparations
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United States
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