United Therapeutics (UTHR) CEO pre-planned option exercise and 9,500-share sale

Rhea-AI Filing Summary

United Therapeutics Corp Chairperson & CEO Martine A. Rothblatt exercised stock options for 9,500 shares of common stock at an exercise price of $146.03 per share and on the same date sold 9,500 shares in open-market trades at weighted average prices between $535.43 and $542.04. The filing states these transactions were executed under a pre-arranged Rule 10b5-1 trading plan adopted on November 7, 2025. After the transactions, she holds 7,150 shares directly and additional indirect holdings through her spouse and family trusts totaling several hundred thousand shares.

Insights

Insider trading and governance analyst

Planned option exercise and matching share sales under a 10b5-1 plan.

Martine A. Rothblatt, Chairperson & CEO of United Therapeutics Corp, exercised options for 9,500 shares at an exercise price of $146.03 and sold 9,500 shares in multiple open-market trades around $535–$542. This is a classic exercise-and-sell pattern.

The filing states the activity occurred under a pre-arranged Rule 10b5-1 trading plan adopted on November 7, 2025, which suggests the timing was scheduled rather than discretionary. After these transactions, she still owns 7,150 shares directly plus substantial indirect holdings via spouse and family trusts.

Given the pre-planned nature and the large remaining indirect position, this looks like routine liquidity and portfolio management rather than a shift in sentiment. The net effect is a 9,500-share reduction visible in this filing, with overall impact on the company’s share base not quantified here.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

ROTHBLATT MARTINE A

(Last) (First) (Middle)

C/O UNITED THERAPEUTICS CORPORATION

1000 SPRING STREET

(Street)

SILVER SPRING MD 20910

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
UNITED THERAPEUTICS Corp [ UTHR ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chairperson & CEO

3. Date of Earliest Transaction (Month/Day/Year)
03/13/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	03/13/2026		M(1)		9,500	A	$146.03	9,630	D
Common Stock	03/13/2026		S(1)		944	D	$535.4265(2)	8,686	D
Common Stock	03/13/2026		S(1)		1,536	D	$536.3204(3)	7,150	D
Common Stock	03/13/2026		S(1)		2,030	D	$537.2939(4)	5,120	D
Common Stock	03/13/2026		S(1)		2,019	D	$538.3121(5)	3,101	D
Common Stock	03/13/2026		S(1)		1,546	D	$539.2636(6)	1,555	D
Common Stock	03/13/2026		S(1)		865	D	$540.2693(7)	690	D
Common Stock	03/13/2026		S(1)		480	D	$541.2083(8)	210	D
Common Stock	03/13/2026		S(1)		80	D	$542.035(9)	130	D
Common Stock								166	I	by Spouse
Common Stock								324,518	I	by Trust(10)
Common Stock								258,117	I	by Trust(11)
Common Stock								45,596	I	by Trust(12)
Common Stock								10,962	I	by Trust(13)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option	$146.03	03/13/2026		M(1)			9,500	03/15/2020	03/15/2027	Common Stock	9,500	$0.00	145,000	D

Explanation of Responses:

1. This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 17, 2027; or (b) December 31, 2026.

2. This transaction was executed in multiple trades at prices ranging from $534.80 to $535.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

3. This transaction was executed in multiple trades at prices ranging from $535.80 to $536.78. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

4. This transaction was executed in multiple trades at prices ranging from $536.82 to $537.81. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

5. This transaction was executed in multiple trades at prices ranging from $537.82 to $538.80. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

6. This transaction was executed in multiple trades at prices ranging from $538.82 to $539.78. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

7. This transaction was executed in multiple trades at prices ranging from $539.84 to $540.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

8. This transaction was executed in multiple trades at prices ranging from $540.93 to $541.73. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

9. This transaction was executed in multiple trades at prices ranging from $542.03 to $542.04. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

10. Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries.

11. Shares held in family trusts as to which the Reporting Person's spouse is sole trustee and sole beneficiary or co-trustee and settlor with power to revoke.

12. Shares held in family trusts as to which the Reporting Person's spouse shares investment power and the Reporting Person and/or immediate family members are beneficiaries.

13. Shares held in family trusts as to which the Reporting Person is sole trustee and sole beneficiary or co-trustee and settlor with power to revoke.

Remarks:

	/s/ John S. Hess, Jr. under Power of Attorney	03/16/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transactions did United Therapeutics (UTHR) report for its CEO?

United Therapeutics CEO Martine Rothblatt exercised options for 9,500 shares and sold 9,500 shares of common stock. The sales were open-market transactions at weighted average prices between about $535 and $542 per share, executed on the same date as the option exercise.

Was the United Therapeutics (UTHR) CEO’s share sale pre-planned under a Rule 10b5-1 plan?

Yes, the CEO’s option exercise and related share sales were carried out under a pre-arranged Rule 10b5-1 trading plan. The plan was adopted on November 7, 2025 and is scheduled to continue until either 1,734,410 options are exercised or December 31, 2026.

How many United Therapeutics (UTHR) shares does the CEO hold after these transactions?

After the reported trades, the CEO directly holds 7,150 United Therapeutics common shares. The filing also shows additional indirect ownership through her spouse and multiple family trusts, with those indirect positions collectively amounting to several hundred thousand shares held for family beneficiaries.

What type of options did the United Therapeutics (UTHR) CEO exercise in this Form 4?

The CEO exercised stock options covering 9,500 shares of United Therapeutics common stock. These options had an exercise price of $146.03 per share and are part of a larger option grant with remaining unexercised options that expire on March 17, 2027, as referenced in the footnotes.

How large was the net share change in this United Therapeutics (UTHR) insider filing?

The filing shows a net sell direction of 9,500 shares for the CEO’s reported transactions. She exercised 9,500 options and sold 9,500 shares, resulting in a 9,500-share net reduction in the position covered by this Form 4, while retaining significant direct and indirect holdings.