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Valion Bio names Dean Zikria interim CEO, sets pay

The agreement sets a $23,333 monthly fee and entitles Zikria to 50,000 RSUs, with another 50,000 subject to a stockholder plan increase and Special Committee approval.

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Rhea-AI Filing Summary

Valion Bio, Inc. (VBIO) appointed Board member Dean Zikria interim Chief Executive Officer effective September 22, 2026; he remains a director. Under a consulting agreement, he is entitled to a $23,333 monthly fee and 50,000 restricted stock units (RSUs). Another 50,000 RSUs are contingent on an increase to the equity plan by stockholders and approval by the Board’s Special Committee. A cash bonus may be awarded upon closing a reverse merger, merger, or acquisition, as determined by the Board or its Compensation Committee. The agreement is scheduled to terminate January 22, 2027, unless mutually extended for up to 12 months from its effective date.

Sheryle Bolton resigned from the Board effective September 17, 2026; the company stated her resignation did not result from a disagreement. Thomas Jensen became Board and Compensation Committee chair, and Jared Malbin became Audit and Risk Committee chair. While serving as interim CEO, Zikria was removed as an independent member of three Board committees. Lisa Wolf continues as President, Chief Operating Officer, and Chief Financial Officer, reporting to Zikria.

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Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers Governance
Key personnel changes including departures, elections, or appointments of directors and executive officers.
Item 7.01 Regulation FD Disclosure Disclosure
Material non-public information disclosed under Regulation Fair Disclosure, often investor presentations or guidance.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, or exhibit attachments filed with this report.
Monthly consulting fee $23,333 per month Fee under Dean Zikria’s consulting agreement
Initial RSUs 50,000 RSUs Entitlement under the equity incentive plan
Additional RSUs 50,000 RSUs Contingent on a stockholder plan increase and Special Committee approval
Agreement termination date January 22, 2027 Unless the parties mutually extend the agreement
Potential extension Up to 12 months Mutual extension from the agreement’s effective date
restricted stock units financial
"entitled to receive 50,000 restricted stock units"
Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.
independent contractor technical
"Mr. Zikria is and will be an independent contractor"
Animal Rule regulatory
"evaluated in animal models under the FDA’s Animal Rule"
A regulatory pathway that allows safety and effectiveness of drugs or vaccines to be judged primarily from well-controlled animal studies when human trials would be unethical or impossible, such as for treatments against rare, lethal exposures. It matters to investors because approval via this route can speed a product to market for urgent or niche needs but carries extra scientific and regulatory risk—think of it as accepting a high-quality dress rehearsal instead of a live show, with requirements for strong animal models and often additional post-approval obligations.
Fast Track regulatory
"received Fast Track and Orphan Drug designations from the FDA"
A fast track designation is a regulatory label that speeds up the review and communication between a drug developer and regulators for treatments addressing serious illnesses or unmet medical needs. For investors, it matters because it can shorten development time and reduce regulatory delays—like getting a VIP lane at the airport—raising the chance of earlier market access and potential revenue, though it does not guarantee approval.
Orphan Drug designations regulatory
"received Fast Track and Orphan Drug designations from the FDA"
A regulatory status granted to medicines that treat rare diseases, giving developers special incentives and protections — for example, reduced fees, tax benefits, and a period of exclusive marketing once approved. Think of it as a government “boost” that lowers development costs and shields a product from direct competition for a time; investors watch for it because it can raise a drug’s commercial value and reduce the financial risk of bringing a treatment for a small patient group to market.
Toll-like Receptor 5 agonist technical
"Entolimod is a novel Toll-like Receptor 5 agonist"
A toll-like receptor 5 (TLR5) agonist is a drug or molecule that binds to and activates TLR5, a protein on certain immune cells that senses bacterial flagellin and triggers innate immune responses. Think of TLR5 as a doorbell on immune cells and an agonist as the button that rings it, prompting inflammation or immune activation; investors care because this mechanism is used in vaccines and cancer or infectious‑disease therapies and affects clinical effects, safety, and regulatory review.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What role will Dean Zikria hold at Valion Bio (VBIO)?

Valion appointed Dean Zikria interim Chief Executive Officer, effective September 22, 2026. He remains a Board member. The company said he will oversee strategic priorities including Entolimod’s clinical advancement and the pursuit of commercial and government partnerships.

What compensation does Valion Bio (VBIO) provide its interim CEO?

Zikria is entitled to a $23,333 monthly fee and 50,000 RSUs. Another 50,000 RSUs are contingent on an increase to the equity plan by stockholders and Special Committee approval. A cash bonus may be awarded upon closing a strategic transaction, as determined by the Board or Compensation Committee.

When does Dean Zikria’s Valion Bio (VBIO) consulting agreement end?

The agreement is scheduled to terminate on January 22, 2027, unless the parties mutually extend it for up to 12 months from its effective date.

Who leads Valion Bio’s (VBIO) Board and committees after the changes?

Thomas Jensen became Board and Compensation Committee chair, and Jared Malbin became Audit and Risk Committee chair. Sheryle Bolton resigned from the Board effective September 17, 2026. Zikria left three Board committees while serving as interim CEO.

What development programs does Valion Bio (VBIO) describe?

Valion identifies Entolimod as its lead candidate, being developed as a potential medical countermeasure for Acute Radiation Syndrome. It is also advancing Entolasta, a next-generation TLR5 agonist for potential broader applications, including oncology supportive care. Entolimod has received Fast Track and Orphan Drug designations from the FDA.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

 

FORM 8-K

 

CURRENT REPORT

 

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

 

Date of Report (Date of earliest event reported): September 17, 2026

 

 

Valion Bio, Inc.

(Exact name of Registrant as Specified in Its Charter)

 

 

Delaware 001-41052 81-4016391
(State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS Employer Identification No.)
     

1305 E. Houston Street,

Building 1, Suite 311

   
San Antonio, Texas   78205
(Address of Principal Executive Offices)   (Zip Code)

 

Registrant’s Telephone Number, Including Area Code: 888 276-6888

 

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

 

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 

Securities registered pursuant to Section 12(b) of the Act:

 

Title of each class   Trading Symbol(s)  
Name of each exchange on which registered
Common Stock, par value $0.0001 per share   VBIO   The Nasdaq Stock Market LLC

 

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

 

Emerging growth company

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.

 

 

   

 

 

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

 

Appointment of Dean Zikria as Interim Chief Executive Officer

 

On September 22, 2026, Valion Bio, Inc. (the “Company”), a Delaware corporation, appointed Dean Zikria as Interim Chief Executive Officer of the Company, effective immediately. Mr. Zikria remains a member of the Company’s Board of Directors (the “Board”).

 

Mr. Zikria, 58, has served as a director on our Board since July 10, 2019. Mr. Zikria brings deep industry experience in allergy and asthma as well as other chronic diseases to the board. Since August 2019, Mr. Zikria has been the Founder, CEO and Chairman of Mind Machine LLC, a Silicon Valley based marketing/advertising agency—focused on the MedTech industry. From June 1, 2021, until January 2023, he served as the Chief Commercial Officer at Intuity Medical Inc., a Silicon Valley MedTech company launching a highly disruptive glucose meter in the diabetes industry. In addition, he has served as Chairman of DZ Advisors, LLC, a company founded by Mr. Zikria in 2017 that provides consulting and advisory services to the medtech, biotech, digital health and pharmaceutical industries; since inception, where he also served as President from December 2017 until May 31, 2021. Mr. Zikria also sits on the boards of the following privately held companies: AsthmaTek, Inc., a startup digital health company in the asthma space; Brev.Dev, Inc., a technology company developing a disruptive platform to aid developers. Mr. Zikria previously served as Chief Executive Officer of Spirosure Inc., a FeNO detection company for asthma diagnostics, from 2014 to 2017. Additionally, he previously served as head of global marketing for Johnson & Johnson’s Animas Corporation within their medical device & diagnostics division. He was head of strategy for Pfizer Pharmaceuticals U.S. Cardiovascular Unit, a division with approximately $7 billion in annual revenues. Mr. Zikria also brings experience in strategic planning, scenario planning and analysis, and mergers and acquisitions, including sourcing, transactions and integration.

 

On September 22, 2026, in connection with his appointment as Interim Chief Executive Officer of the Company, the Company and Mr. Zikria entered into a consulting agreement (the “Consulting Agreement”), pursuant to which Mr. Zikria (i) is entitled to receive a monthly fee of $23,333 per month; (ii) is entitled to receive 50,000 restricted stock units (“RSUs”) to be issued pursuant to a nonstatutory equity grant under the Company’s Amended and Restated 2021 Equity Incentive Plan, as amended (the “Plan”); (iii) is entitled to receive another 50,000 RSUs upon an increase in the Company’s Plan by the Company’s stockholders, and subject to the approval of the Special Committee of the Board and (iv) may be eligible to receive a cash bonus, as determined by the Board or the Compensation Committee of the Board, upon closing of a strategic transaction (i.e., a reverse merger, a merger, or acquisition).

 

Pursuant to the Consulting Agreement, Mr. Zikria is and will be an independent contractor. Nothing contained in the Consulting Agreement is intended or should be construed to make or constitute Mr. Zikria as an employee or agent of the Company or a partner or co-venturer with the Company. The Consulting Agreement will terminate on January 22, 2027, unless mutually extended by the parties up to twelve (12) months from the effective date of the Consulting Agreement.

 

The foregoing summary of the Consulting Agreement does not purport to be complete and is qualified in its entirety by reference to the full text of the Consulting Agreement, a copy of which is filed as Exhibit 10.1 to this Current Report on Form 8-K (this “Current Report”) and is incorporated herein by reference.

 

 

 

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There are no family relationships between Mr. Zikria and any of the Company’s directors, executive officers or persons nominated or chosen by the Company to become a director or executive officer. Other than as previously disclosed, the Company is not aware of any transactions or relationships between Mr. Zikria and the Company that would require disclosure under Item 404(a) of Regulation S-K under the Securities Exchange Act of 1934, as amended (the “Exchange Act”).

 

Board Resignation

 

On September 17, 2026, Sheryle Bolton notified the Company of her decision to resign from the Company’s Board, effective immediately. Ms. Bolton’s resignation was not the result of any disagreement with the Company on any matter relating to the Company’s operations, policies or practices.

 

Board Committee Appointments

 

On September 17, 2026, the Company appointed Thomas Jensen as Chair of the Board and Chair of the Board’s Compensation Committee, effective immediately.

 

On September 17, 2026, the Company appointed Jared Malbin as Chair of the Board’s Audit and Risk Committee, effective immediately.

 

Mr. Zikria was removed as an independent member from the Board’s Audit and Risk Committee, Compensation Committee and Nominations and Corporate Governance Committee while he serves as Interim Chief Executive Officer.

 

Item 7.01 Regulation FD Disclosure.

 

On September 23, 2026, the Company issued a press release announcing its leadership changes discussed in Item 5.02 above. A copy of the press release is being furnished as Exhibit 99.1 to this Current Report and is incorporated by reference herein.

 

The information set forth under Item 7.01 of this Current Report, including Exhibit 99.1 attached hereto, is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of such section. The information in Item 7.01 of this Current Report, including Exhibit 99.1, shall not be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, regardless of any incorporation by reference language in any such filing, except as expressly set forth by specific reference in such a filing. This Current Report will not be deemed an admission as to the materiality of any information in this Current Report that is required to be disclosed solely by Regulation FD.

 

Item 9.01 Financial Statements and Exhibits.

 

(d) Exhibits.

 

Exhibit No.   Description
10.1   Consulting Agreement, by and between the Company and Dean Zikria, effective September 22, 2026.
99.1   Press Release, dated September 23, 2026.
104   Cover Page Interactive Data File (embedded within the Inline XBRL document).

 

 

 

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SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

  

      VALION BIO, INC.
       
Date: September 23, 2026 By: /s/ Melinda Lackey
      Name: Melinda Lackey
Title: General Counsel and Senior Vice President of Legal Affairs

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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Exhibit 99.1

 

Valion Appoints Life Sciences Veteran Dean Zikria as Interim CEO and Announces Board Leadership Transitions

 

Leadership changes strengthen alignment and execution as Company advances Entolimod and evaluates strategic, commercial and government opportunities

 

SAN ANTONIO, TX – September 23, 2026 Valion Bio, Inc. (Nasdaq: VBIO) (“Valion” or the “Company”), a clinical-stage biopharmaceutical company, today announced decisive changes to its executive leadership team and Board of Directors (the “Board”). These leadership transitions are intended to strengthen organizational alignment and support focused execution as Valion advances its Entolimod and other development programs and evaluates strategic opportunities.

 

Dean Zikria, a current member of the Board, has been appointed Interim Chief Executive Officer (“CEO”). In this role, Mr. Zikria will oversee Valion’s strategic priorities, including accelerating the clinical advancement of Entolimod and aggressively pursuing commercial and government partnerships.

 

Mr. Zikria brings a compelling blend of scientific innovation, pharmaceutical commercialization and emerging biotech experience to Valion’s next phase of growth. His career began at Columbia University Medical Center, where he co-invented novel therapeutics studied for potential applications in traumatic brain injury, hemorrhagic shock and battlefield medicine, and later included seven years at Pfizer, where he held strategy and business development roles within its $7 billion U.S. cardiovascular business, supporting a portfolio that included LIPITOR®, then the world’s best-selling drug. Today, he remains at the forefront of emerging biotechnology as an advisor and selection committee member for UC Berkeley’s SkyDeck accelerator, evaluating new therapeutic technologies and advising early-stage companies on R&D strategy, financing, leadership and commercialization.

 

Lisa Wolf will continue to serve as Valion’s President, Chief Operating Officer and Chief Financial Officer, leading the Company’s financial and operational functions and reporting to Mr. Zikria.

 

Valion also announced that Thomas Jensen has been appointed Chair of the Board and Chair of its Compensation Committee. He succeeds Sheryle Bolton, who has stepped down from the Board and its committees. In addition, Jared Malbin has been appointed Chair of the Board’s Audit Committee.

 

“On behalf of the Board, I want to thank Sheryle for her leadership, service and many contributions to Valion,” said Mr. Jensen. “These transitions establish clear accountability and strengthen alignment between our Board and management team as Valion enters an important stage of its development. Dean’s familiarity with the Company, its programs and its strategic priorities provides continuity while sharpening our focus on disciplined capital allocation, operational execution and long-term shareholder value.”

 

“Dean brings the experience, judgment and strategic perspective needed to lead Valion during this next phase,” Mr. Jensen continued. “The Board looks forward to working closely with him and the broader management team as the Company advances Entolimod, evaluates high-potential opportunities and works toward milestones that could create meaningful value for patients and shareholders.”

 

“I am honored to assume this expanded role at an important point in Valion’s evolution,” said Mr. Zikria. “Valion has promising development programs and a dedicated team working to translate the Company’s science into meaningful outcomes. My immediate priorities are to work closely with Lisa and the rest of our team to maintain momentum, sharpen execution and concentrate our resources on Entolimod and the opportunities we believe offer the greatest potential to create lasting value.”

 

 

 

 

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About Valion Bio, Inc.

 

Valion Bio, Inc. (Nasdaq: VBIO) is developing biologics that activate innate immune pathways for cytoprotection and modulate immune responses in conditions driven by radiation, disease and immune dysregulation.

 

The Company’s lead candidate, Entolimod, is being developed as a potential medical countermeasure for Acute Radiation Syndrome and has been evaluated in animal models under the U.S. Food and Drug Administration’s (“FDA”) Animal Rule, which allows the Agency to approve new drugs and biological products based on animal efficacy studies when human clinical trials are not ethical or feasible, such as in the case of acute radiation exposure. Entolimod is a novel Toll-like Receptor 5 agonist designed to activate NF-κB signaling pathways associated with cellular protection, tissue recovery and immune response. The product candidate has received Fast Track and Orphan Drug designations from the FDA.

 

Valion is also advancing Entolasta, a next-generation TLR5 agonist designed for potential use in broader therapeutic applications, including oncology supportive care. The Company’s pipeline includes potential programs in neutropenia and immune dysfunction.

 

Valion’s wholly owned subsidiary, Velocity Bioworks, is a biologics contract development and manufacturing organization providing development and manufacturing services to Valion to support its internal pipeline, with the objective of increasing manufacturing control, reducing costs, accelerating development timelines and strengthening domestic supply-chain security.

 

For more information, visit www.valionbio.com.

 

Forward-Looking Statements

 

This press release may contain "forward-looking statements" that are subject to substantial risks and uncertainties. All statements, other than statements of historical fact, contained in this press release are forward-looking statements. Forward-looking statements contained in this press release may be identified by the use of words such as “anticipate,” “believe,” “contemplate,” “could,” “estimate,” “expect,” “intend,” “seek,” “may,” “might,” “plan,” “potential,” “predict,” “project,” “target,” “aim,” “should,” “will” “would,” or the negative of these words or other similar expressions, although not all forward-looking statements contain these words. Forward-looking statements are based on Valion’s current expectations and are subject to inherent uncertainties, risks, and assumptions that are difficult to predict. Further, certain forward-looking statements are based on assumptions as to future events that may not prove to be accurate. Actual results could differ materially from those contained in any forward-looking statement as a result of various factors, including, without limitation: the continued listing of the Company’s common stock on the Nasdaq Capital Market; and the Company's ability to maintain compliance with applicable listing standards on the Nasdaq Capital Market. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements. For a discussion of other risks and uncertainties, and other important factors, any of which could cause Valion’s actual results to differ from those contained in the forward-looking statements, see Valion’s filings with the SEC, including, its Annual Report on Form 10-K for the year ended December 31, 2025, filed with the SEC on March 30, 2026, under the heading "Risk Factors"; as well as the Company’s subsequent filings with the SEC. Forward-looking statements contained in this press release are made as of this date, and Valion undertakes no duty to update such information except as required by applicable law.

 

Investor and Media Contact

 

Stephen Kilmer

(646) 274-3580

stephen.kilmer@valionbio.com

 

 

 

 

 

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