Astellas cash lifts Vir Biotechnology (Nasdaq: VIR) to Q2 profit
Rhea-AI Filing Summary
Vir Biotechnology, Inc. reported second quarter 2026 results highlighted by $238.9 million in total revenues, primarily license and collaboration revenue from a $240.0 million upfront payment from Astellas, and net income of $80.1 million, or $0.48 per share basic, versus a $111.0 million loss a year earlier.
Cash, cash equivalents and investments were approximately $1.01 billion as of June 30, 2026, after receiving a $75 million equity investment from Astellas and making a $48.0 million pass-through payment to Sanofi; this balance is expected to fund operations into the second half of 2028.
In chronic hepatitis delta, Phase 2 SOLSTICE data showed undetectable HDV RNA in 88% of combination-treated participants at Week 96, with 97% in a last-observation analysis and a generally well tolerated profile. The ECLIPSE registrational program is fully enrolled, with key Phase 3 data expected between late 2026 and early 2027, while the Astellas collaboration advances VIR-5500 and other PRO-XTEN T-cell engagers through multiple Phase 1 dose-expansion cohorts.
Positive
- Vir generated net income of $80.1 million in Q2 2026, or $0.48 per share basic, compared with a $111.0 million net loss in the prior-year quarter, driven largely by collaboration revenue from Astellas.
- Quarter-end cash, cash equivalents and investments totaled $1.01 billion, and the company expects this liquidity to fund operations into the second half of 2028, providing a multi-year operating runway.
Negative
- None.
Filing Explained
The common-share base stood at 169,185,671 on June 30 versus 139,474,954 at year-end, while trial readouts remain ahead.
The June 30 balance sheet reports 169,185,671 common shares issued and outstanding, versus 139,474,954 on
The filing separately reports a
The filing also states that ECLIPSE 2 enrollment is complete and that the full ECLIPSE registrational program is enrolled; topline data are expected for ECLIPSE 1 in
8-K Event Classification
2 items: 2.02, 9.01
2 items
Item 2.02
Results of Operations and Financial Condition
Financial
Disclosure of earnings results, typically an earnings press release or preliminary financials.
Item 9.01
Financial Statements and Exhibits
Exhibits
Financial statements, pro forma financial information, and exhibit attachments filed with this report.
Key Figures
Cash, cash equivalents and investments: $1.01 billion
Total revenues: $238.9 million
Net income: $80.1 million
+4 more
7 metrics
Cash, cash equivalents and investments
$1.01 billion
As of June 30, 2026; expected to fund operations into the second half of 2028
Total revenues
$238.9 million
For the quarter ended June 30, 2026, primarily license and collaboration revenue from an Astellas upfront payment
Net income
$80.1 million
Net income for Q2 2026, compared with a net loss of $111.0 million in Q2 2025
Research and development expenses
$135.3 million
Q2 2026 R&D expenses, including $5.5 million of non-cash stock-based compensation
Selling, general and administrative expenses
$30.2 million
Q2 2026 SG&A expenses, including $6.9 million of non-cash stock-based compensation
Astellas upfront payment
$240.0 million
Upfront payment received in Q2 2026 under the global strategic collaboration with Astellas
Equity investment from Astellas
$75 million
Equity investment payment received in Q2 2026 as part of the Astellas collaboration
Key Terms
PRO-XTEN® masking technology, chronic hepatitis delta (CHD), metastatic castration-resistant prostate cancer (mCRPC), Target Not Detected (TND), +1 more
5 terms
PRO-XTEN® masking technology medical
"The universal PRO-XTEN® masking technology is designed to keep the TCEs inactive"
chronic hepatitis delta (CHD) medical
"ECLIPSE is a registrational program to evaluate the safety and efficacy in patients with chronic hepatitis delta (CHD)"
metastatic castration-resistant prostate cancer (mCRPC) medical
"evaluating VIR-5500 in taxane naïve metastatic castration-resistant prostate cancer (mCRPC)"
An advanced form of prostate cancer that has spread beyond the prostate and keeps growing even after standard hormone-lowering treatments no longer work. Investors pay attention because it creates a clear need for new therapies and diagnostic tools: successful clinical trial results, regulatory approvals, or safe effective drugs can drive substantial revenue and stock moves, while failed trials or safety problems can sharply reduce a company’s value—like pests that survive a common pesticide and demand a new solution.
Target Not Detected (TND) medical
"achieved undetectable hepatitis delta virus RNA (HDV RNA Target Not Detected, TND)"
registrational program regulatory
"ECLIPSE is a registrational program to evaluate the safety and efficacy of elebsiran in combination"
A registrational program is the set of late-stage clinical studies and regulatory steps designed to show that a drug or medical product is safe and effective enough to win formal approval from health authorities. Think of it like the final licensing exams a product must pass before it can be sold widely; investors watch these programs closely because successful results clear the way to market access, revenue potential, and lower regulatory risk, while failures can halt commercial plans.
Earnings Snapshot
Total revenues: $238.9 million · Guidance included
Quarter ended June 30, 2026
Total revenues
$238.9 million
Increased substantially from the prior-year quarter, driven primarily by license and collaboration revenue from a $240.0 million upfront payment received from Astellas.
Net income (loss)
Net income of $80.1 million
Reversed from a net loss of $111.0 million in the same quarter of 2025, reflecting higher collaboration revenue.
R&D expenses
$135.3 million
Increased from $97.5 million in Q2 2025, primarily due to a $48.0 million milestone payment to Sanofi and higher CHD manufacturing costs.
SG&A expenses
$30.2 million
Increased from $22.3 million in Q2 2025, mainly reflecting one-time advisory and legal fees related to the Astellas agreement.
Guidance
The company expects its cash, cash equivalents and investments to fund operations into the second half of 2028.
AI-generated analysis. How Rhea-AI works. Not financial advice.
FAQ
What were Vir Biotechnology (VIR)'s key financial results for Q2 2026?
Vir Biotechnology reported $238.9 million in total revenues and $80.1 million in net income for Q2 2026, or $0.48 per share basic, mainly reflecting license and collaboration revenue from a $240.0 million upfront payment received from Astellas.
How strong is Vir Biotechnology (VIR)'s cash position and runway?
As of June 30, 2026, Vir held about $1.01 billion in cash, cash equivalents and investments. Based on current plans and the Astellas collaboration, the company expects this balance to fund operations into the second half of 2028.
What clinical data did Vir Biotechnology (VIR) report for chronic hepatitis delta?
Phase 2 SOLSTICE data showed 88% (28/32) of patients on elebsiran plus tobevibart achieved undetectable HDV RNA at Week 96, rising to 97% (31/32) in a last-observation analysis, with the combination generally well tolerated and no treatment-related serious adverse events reported.
What is the status and timing of Vir Biotechnology (VIR)'s ECLIPSE CHD program?
The ECLIPSE registrational program for CHD is now fully enrolled across three trials. Topline data from Phase 3 ECLIPSE 1 are expected in Q4 2026, with ECLIPSE 2 and 3 topline data anticipated in the first quarter of 2027.
What are the key terms of Vir Biotechnology (VIR)'s collaboration with Astellas?
Vir closed a global strategic collaboration with Astellas, receiving a $240.0 million upfront payment and a $75 million equity investment. The partnership focuses on advancing PSMA-targeted T-cell engager VIR-5500 in prostate cancer, including multiple Phase 1 dose-expansion cohorts.
How is Vir Biotechnology (VIR) progressing its oncology pipeline beyond VIR-5500?
Vir is evaluating VIR-5818, a HER2-targeted T-cell engager, in a Phase 1 dose-escalation trial with updated data expected in the second half of 2026. A Phase 1 trial of VIR-5525, an EGFR-targeted T-cell engager, continues enrollment in monotherapy and pembrolizumab combination cohorts.
Did Vir Biotechnology (VIR) make any notable corporate governance changes?
Yes. Vir appointed Timothy Coughlin, CPA to its Board of Directors and as Chair of the Audit Committee, adding financial and audit oversight expertise as the company advances its clinical and collaboration programs.
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
________________________________________
FORM 8-K
________________________________________
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): August 5, 2026
________________________________________
(Exact name of Registrant as Specified in Its Charter)
________________________________________
| (State or Other Jurisdiction of Incorporation) | (Commission File Number) | (IRS Employer Identification No.) | ||||||
| (Address of Principal Executive Offices) | (Zip Code) | |||||||
Registrant’s Telephone Number, Including Area Code: (415 ) 906-4324
(Former Name or Former Address, if Changed Since Last Report)
________________________________________
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
| Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) | |||||
| Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) | |||||
| Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) | |||||
| Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) | |||||
Securities registered pursuant to Section 12(b) of the Act:
| Title of each class | Trading Symbol(s) | Name of each exchange on which registered | ||||||||||||
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).
Emerging growth company o
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o
Item 2.02 Results of Operations and Financial Condition.
On August 5, 2026, Vir Biotechnology, Inc. (the Company) issued a press release announcing its financial results for the quarter ended June 30, 2026. A copy of the press release is furnished herewith as Exhibit 99.1 and is incorporated herein by reference.
The information in this Item 2.02, including the attached Exhibit 99.1, is being furnished and shall not be deemed “filed” for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the Exchange Act), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference into any filing made by the Company under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such a filing.
Item 9.01 Financial Statements and Exhibits.
(d) Exhibits
| Exhibit No. | Description | |||||||
| 99.1 | Press Release of the Company, dated August 5, 2026 | |||||||
| 104 | Cover Page Interactive Data File (embedded within the Inline XBRL document) | |||||||
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
| VIR BIOTECHNOLOGY, INC. | |||||||||||
| Date: | August 5, 2026 | By: | /s/ Marianne De Backer | ||||||||
| Marianne De Backer, M.Sc., Ph.D., MBA President, Chief Executive Officer and Director | |||||||||||
Exhibit 99.1
Vir Biotechnology Provides Corporate Update and Reports Second Quarter 2026 Financial Results
– Phase 2 SOLSTICE data presented at the EASL Congress showed that elebsiran and tobevibart achieved undetectable HDV RNA in 88% of participants with chronic hepatitis delta (CHD) at Week 96 of treatment
– Topline data from Phase 3 ECLIPSE 1 trial expected in the fourth quarter of 2026
– Closed global strategic collaboration with Astellas and initiated additional VIR-5500 Phase 1 monotherapy and combination therapy dose-expansion cohorts in patients with metastatic prostate cancer
– Ended quarter with over $1.0 billion in cash, cash equivalents and investments
– Conference call scheduled for August 5, 2026, at 4:30 p.m. ET / 1:30 p.m. PT
SAN FRANCISCO, August 5, 2026 – Vir Biotechnology, Inc. (Nasdaq: VIR), today provided a corporate update and reported financial results for the second quarter ended June 30, 2026.
“This is a pivotal time for the CHD community, when availability of new therapies could improve awareness, testing and access to care. At EASL, experts emphasized that achieving durable suppression of hepatitis delta virus to undetectable levels is a key predictor of improved clinical outcomes for people with CHD. Our Week 96 SOLSTICE results demonstrate the potential of our dual-acting elebsiran and tobevibart combination regimen to rapidly achieve undetectable virus in most patients and raise the bar for treatment of this devastating condition,” said Marianne De Backer, Chief Executive Officer of Vir Biotechnology. “Beyond CHD, we remain focused on rapid execution of our joint clinical program with Astellas in prostate cancer and have initiated monotherapy and combination therapy dose-expansion cohorts in our VIR-5500 Phase 1 study that will help inform pivotal trial design.”
Pipeline Programs
Chronic Hepatitis Delta (CHD)
•The Company completed enrollment in the Phase 3 ECLIPSE 2 trial, and the entire ECLIPSE registrational program is now fully enrolled. ECLIPSE 2 evaluates the efficacy and safety of switching from bulevirtide to elebsiran and tobevibart in people with CHD who have not achieved viral suppression with bulevirtide therapy and is intended support medication transitions as appropriate. These data, along with data from ECLIPSE 1 and 3, will be part of a comprehensive global filing package.
◦Topline data from the Phase 3 ECLIPSE 1 trial are expected in the fourth quarter of 2026.
◦Topline data from the ECLIPSE 2 and ECLIPSE 3 trials are expected in the first quarter of 2027.
•The Company presented complete Week 96 Phase 2 SOLSTICE data at the European Association for the Study of the Liver (EASL) Congress in May 2026.
◦In the intent-to-treat (ITT) analysis, the data showed 88% (28/32) of participants treated with the combination of elebsiran and tobevibart achieved undetectable hepatitis delta virus RNA (HDV RNA Target Not Detected, TND) compared to 53% (17/32) of participants on antibody monotherapy.
◦In the last observation carried forward analysis, the data showed the combination regimen achieved HDV RNA TND in 97% (31/32) of participants.
◦The combination regimen continues to be generally well tolerated. Treatment-emergent adverse events were generally mild to moderate and transient, and there were no treatment-related serious adverse events or discontinuations.
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Solid Tumors
VIR-5500
•The Company closed its global strategic collaboration with Astellas to advance PSMA-targeted, PRO-XTEN® dual-masked T-cell engager (TCE) VIR-5500 for the treatment of prostate cancer. The companies have built a strong operational infrastructure for collaboration and rapidly worked together on Phase 1 trial design to advance the dose-expansion cohorts.
•The Company initiated additional Phase 1 dose-expansion cohorts evaluating VIR-5500 at Q3W 800/2000/3500 µg/kg step-up dosing. The first patients were dosed in three monotherapy cohorts evaluating VIR-5500 in taxane naïve metastatic castration-resistant prostate cancer (mCRPC), radioligand therapy naïve mCRPC and radioligand therapy exposed mCRPC, and one combination cohort evaluating VIR-5500 in combination with enzalutamide in early-line mCRPC.
•The Company anticipates initiating two additional Phase 1 dose-expansion cohorts, including VIR-5500 in combination with docetaxel in early-line mCRPC and VIR-5500 in combination with darolutamide in metastatic hormone-sensitive prostate cancer.
•The Company anticipates initiating pivotal Phase 3 trials in 2027.
VIR-5818
•The Company expects to report updated dose-escalation data from its Phase 1 trial evaluating VIR-5818, a HER2-targeted PRO-XTEN® dual-masked TCE, as a monotherapy and in combination with pembrolizumab, in the second half of 2026. The dose-escalation parts of the Phase 1 trial have a basket design, enrolling across multiple tumor types.
VIR-5525
•The Phase 1 trial of VIR-5525, an EGFR-targeted PRO-XTEN® dual-masked TCE, as a monotherapy and in combination with pembrolizumab continues enrollment as expected.
Preclinical Pipeline Candidates
•The Company is currently progressing a number of PRO-XTEN® masked TCEs in preclinical studies directed at clinically validated targets with potential applications across a variety of solid tumors.
Corporate Update
•The Company appointed Timothy Coughlin, CPA to its Board of Directors and as Chair of the Audit Committee.
Second Quarter 2026 Financial Results
Cash, Cash Equivalents and Investments: As of June 30, 2026, the Company had approximately $1.01 billion in cash, cash equivalents and investments, representing an increase of approximately $198.5 million during the second quarter of 2026. During the second quarter of 2026, the Company received a $240.0 million upfront payment and a $75 million equity investment payment from Astellas and made a $48.0 million pass-through payment to Sanofi.
Revenues: Total revenues for the second quarter of 2026 were $238.9 million, primarily reflecting license and collaboration revenue recognized in connection with the $240.0 million upfront payment received from Astellas in the quarter.
Research and Development (R&D) Expenses : R&D expenses for the second quarter of 2026 were $135.3 million, which included $5.5 million of non-cash stock-based compensation expense, compared to $97.5 million for the same period in 2025, which included $6.9 million of non-cash stock-based compensation expense. The increase was primarily driven by a $48.0 million milestone payment to Sanofi triggered by the closing of our agreement with Astellas, as well as higher CHD contract manufacturing costs associated with process performance qualification batches in preparation for commercialization.
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Selling, General and Administrative (SG&A) Expenses: SG&A expenses for the second quarter of 2026 were $30.2 million, which included $6.9 million of non-cash stock-based compensation expense, compared to $22.3 million for the same period in 2025, which included $5.5 million of non-cash stock-based compensation expense. The increase was primarily due to one-time advisory and legal fees in connection with the closing of our Astellas agreement.
Net Income (Loss): Net income for the second quarter of 2026 was $80.1 million, or $0.48 per share, basic and $0.47 per share, diluted, compared to a net loss of $111.0 million, or $0.80 per share, basic and diluted for the same period in 2025. The change from net loss to net income was primarily driven by $238.9 million in license and collaboration revenue recognized this quarter from the $240.0 million Astellas upfront payment.
2026 Financial Guidance
Based on our current operating plans, including the net effects of the Astellas global collaboration, the Company expects its cash, cash equivalents and investments to fund operations into the second half of 2028.
Conference Call
Vir Biotechnology will host its second quarter 2026 financial results conference call at 4:30 p.m. ET / 1:30 p.m. PT today. A live webcast will be available at https://investors.vir.bio and will be archived for 30 days.
About the ECLIPSE Registrational Program
ECLIPSE is a registrational program to evaluate the safety and efficacy of elebsiran in combination with tobevibart in patients with chronic hepatitis delta (CHD). ECLIPSE includes three randomized, controlled trials designed to evaluate the combination therapy in comparison to deferred treatment or bulevirtide. ECLIPSE 1 (NCT06903338) is a Phase 3 trial evaluating the safety and efficacy of elebsiran in combination with tobevibart compared to deferred treatment in the U.S. or other regions where bulevirtide use is limited. ECLIPSE 2 (NCT07128550) is a Phase 3 trial evaluating the efficacy and safety of switching to elebsiran and tobevibart in people with CHD who have not achieved viral suppression with bulevirtide therapy. ECLIPSE 1 and 2 are designed to provide the registrational efficacy and safety data needed for potential submission to global regulatory agencies. ECLIPSE 3 (NCT07142811) is a Phase 2b head-to-head trial evaluating combination elebsiran and tobevibart compared with bulevirtide in bulevirtide-naïve patients, and it is designed to provide important supportive data to help establish access and reimbursement in key markets.
About Elebsiran and Tobevibart
Elebsiran and tobevibart are investigational agents being evaluated as a novel combination regimen administered monthly as two separate sequential subcutaneous injections for the treatment of chronic hepatitis delta (CHD). The combination is designed to disrupt the hepatitis delta virus (HDV) life cycle at multiple points by addressing both viral entry and the sustained presence of hepatitis B surface antigen (HBsAg) that enables ongoing HDV replication.
Elebsiran is an investigational hepatitis B virus-targeting small interfering ribonucleic acid (siRNA) licensed from Alnylam Pharmaceuticals, Inc. It is designed to degrade hepatitis B virus RNA transcripts and limit the production of HBsAg.
Tobevibart is an investigational broadly neutralizing monoclonal antibody (mAb) targeting HBsAg. It is designed to inhibit the entry of hepatitis B and hepatitis delta viruses into hepatocytes and to reduce the level of circulating viral and subviral particles in the blood. Tobevibart was identified using Vir Biotechnology’s proprietary mAb discovery platform. The Fc domain has been engineered to increase immune engagement and clearance of HBsAg immune complexes and incorporates Xencor’s Xtend™ technology to extend half-life.
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About Chronic Hepatitis Delta (CHD)
CHD is the most severe form of chronic viral hepatitis1 and was recently classified as carcinogenic by the International Agency for Research on Cancer.2 People living with the disease rapidly progress to cirrhosis, liver failure3 and liver-related death.1 Because ongoing hepatitis delta virus (HDV) replication drives disease progression, achieving undetectable virus, as defined by HDV RNA TND (target not detected), is considered an important virologic marker associated with improved clinical outcomes in CHD.4 Individuals with CHD who have detectable HDV RNA are at a higher risk of experiencing any liver-related event, including developing compensated and decompensated cirrhosis, hepatocellular carcinoma, liver transplantation and mortality, compared to patients with undetectable HDV RNA.4 There are currently limited approved treatments in the U.S. and globally.
About VIR-5500, VIR-5818 and VIR-5525
VIR-5500, VIR-5818 and VIR-5525 are investigational, clinical candidates currently being evaluated for the treatment of solid tumors. These assets leverage the universal PRO-XTEN® masking technology and target PSMA, HER2 and EGFR, respectively.
T-cell engagers (TCEs) are powerful anti-tumor agents that can direct the immune system, specifically T-cells, to destroy cancer cells. The universal PRO-XTEN® masking technology is designed to keep the TCEs inactive (or masked) until they reach the tumor microenvironment, where tumor-specific proteases cleave off the mask and activate the TCEs, leading to killing of cancer cells by T-cells. By confining the activity to the tumor microenvironment, we aim to circumvent the traditionally high toxicity associated with TCEs and increase their efficacy and tolerability. Additionally, the mask is designed to help drug candidates stay in the bloodstream longer in their inactive form, allowing them to better reach the site of action and potentially allowing less frequent dosing regimens for patients and clinicians.
About Advanced Prostate Cancer
Prostate cancer remains a significant global health burden, representing the second leading cause of cancer-related mortality in men behind lung cancer.5 While diagnostic and therapeutic advances like androgen-directed therapy can improve outcomes in earlier settings, most patients ultimately relapse and develop metastatic hormone sensitive prostate cancer (mHSPC).6 mHSPC is characterized by its responsiveness to intensified hormonal interventions designed to reduce androgen levels or block their action. The majority of these patients eventually progress to metastatic castration-resistant prostate cancer (mCRPC).7 This stage is associated with poor clinical outcomes, including limited durability of existing therapies, with a 5-year survival rate of approximately 30%.8 There is a critical need for safer, more effective and precisely targeted therapies capable of improving long term disease control and quality of life across the prostate cancer continuum.
About Vir Biotechnology, Inc.
Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies. Vir Biotechnology routinely posts information that may be important to investors on its website.
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References:
1 National Institute of Diabetes and Digestive and Kidney Diseases. Hepatitis D. NIDDK. Published November 2024. Accessed September 2025. Hepatitis D - NIDDK (nih.gov).
2 Karagas, Margaret R et al., “Carcinogenicity of hepatitis D virus, human cytomegalovirus, and Merkel cell polyomavirus” The Lancet Oncology, vol. 26, no. 8 (2025): 994 – 995. doi: 10.1016/S1470-2045(25)00403-6.
3 Center for Disease Control and Prevention. Hepatitis D FAQs. CDC. Published March 2020. Accessed September 2025. What is Hepatitis D - FAQ | CDC.
4 Gish R. (2024). Association of hepatitis delta virus with liver morbidity and mortality: A systematic literature review and meta-analysis. Hepatology. 79: 1129-1140.
5 Kratzer TB, et. al. “Prostate cancer statistics, 2025.” CA Cancer J Clin. vol. 75 no. 6 (2025): 485-497. doi:10.3322/caac.70028.
6 Bernard-Terrier A & Beltran H. “Exploring the biology of metastatic hormone-sensitive prostate cancer: on the road to precision medicine.” J Clin Invest. vol. 136 no. 3 (2026):e200920. doi: 10.1172/JCI200920.
7 Leith A, et. al. “Real-World Treatment Patterns in Metastatic Castration-Resistant Prostate Cancer Across Europe (France, Germany, Italy, Spain, and the United Kingdom) and Japan.” Adv Ther. vol. 39 (2022): 2236-2255. doi: 10.1007/s12325-022-02073-w.
8 Huo, X et al. “Predicting Survival in Metastatic Castration-Resistant Prostate Cancer Patients: Development of a Prognostic Nomogram.” Studies in health technology and informatics vol. 323 (2025): 164-168. doi:10.3233/SHTI250070.
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Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “should,” “could,” “may,” “might,” “will,” “plan,” “potential,” “aim,” “expect,” “anticipate,” “promising” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) are intended to identify forward-looking statements. Forward-looking statements contained in this press release include, but are not limited to, statements regarding: Vir Biotechnology’s cash balance and anticipated runway; the potential for new therapies to improve awareness, testing and access to care for the CHD community; Vir Biotechnology’s future financial and operating results and its expectations related thereto, including Vir Biotechnology’s financial guidance; the therapeutic and commercial potential of Vir Biotechnology's CHD program, as well as Vir Biotechnology's strategy, plans and expectations related thereto; the therapeutic and commercial potential of VIR-5500 and the other assets in Vir Biotechnology's oncology solid tumor clinical portfolio, preclinical pipeline and the PRO-XTEN® masking technology, as well as Vir Biotechnology's strategy, plans and expectations related thereto; the potential of and Vir Biotechnology’s expectations for its other pipeline programs; Vir Biotechnology’s plans and expectations for its clinical development programs, including protocols for and enrollment into ongoing and planned clinical studies, potential partnering opportunities, and data readouts and presentations, as well as anticipated timelines; the potential benefits, safety and efficacy of Vir Biotechnology’s investigational therapies; and any assumptions underlying any of the foregoing. Many factors may cause differences between current expectations and actual results, including, without limitation: unexpected safety or efficacy data or results observed during clinical studies or in data readouts, including the occurrence of adverse safety events; risks of unexpected costs, delays or other unexpected hurdles; the timing and amount of Vir Biotechnology’s actual operating expenses, as determined in accordance with U.S. Generally Accepted Accounting Principles; difficulties in collaborating with other companies, some of whom may be competitors of Vir Biotechnology or otherwise have divergent interests, and uncertainty as to whether the benefits of Vir Biotechnology’s various collaborations can ultimately be achieved in the amounts and on the timeline Vir Biotechnology expects; challenges in accessing manufacturing capacity; clinical site activation rates or clinical enrollment rates that are lower than expected; the timing and outcome of Vir Biotechnology’s planned interactions with regulatory authorities, as well as general difficulties in obtaining any necessary regulatory approvals; successful development and/or commercialization of alternative product candidates by Vir Biotechnology’s competitors, as well as changes in expected or existing competition; Vir Biotechnology’s use of AI and machine learning in its efforts to engineer next-generation proteins and in other research and development efforts; geopolitical changes or other external factors; and unexpected litigation or other disputes. In light of these risks and uncertainties, the events or circumstances referred to in the forward-looking statements may not occur. Drug development and commercialization involve a high degree of risk, and only a small number of research and development programs result in commercialization of a product. Results in early-stage clinical studies may not be indicative of full results or results from later-stage or larger-scale clinical studies and do not ensure regulatory approval. The actual results may vary from the anticipated results, and the variations may be material. You are cautioned not to place undue reliance on any scientific data presented or these forward-looking statements, which are based on Vir Biotechnology’s available information, expectations and assumptions as of the date of this press release. Other factors that may cause Vir Biotechnology’s actual results to differ from those expressed or implied in the forward-looking statements in this press release are discussed in Vir Biotechnology’s filings with the U.S. Securities and Exchange Commission, including the section titled “Risk Factors” contained therein. Except as required by law, Vir Biotechnology assumes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise.
Vir Biotechnology has exclusive rights to the universal PRO-XTEN® masking platform for oncology and infectious disease. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.
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VIR BIOTECHNOLOGY, INC.
Condensed Consolidated Balance Sheets
(in thousands, except share and per share data)
(unaudited)
| June 30, 2026 | December 31, 2025 | ||||||||||
| ASSETS | |||||||||||
| CURRENT ASSETS: | |||||||||||
| Cash and cash equivalents | $ | 278,729 | $ | 232,185 | |||||||
| Short-term investments | 249,864 | 228,753 | |||||||||
| Restricted cash and cash equivalents, current | 1,929 | 1,922 | |||||||||
| Equity investments | 4,133 | 6,077 | |||||||||
| Prepaid expenses and other current assets | 39,084 | 45,143 | |||||||||
| Total current assets | 573,739 | 514,080 | |||||||||
| Intangible assets, net | 7,702 | 7,850 | |||||||||
| Goodwill | 16,937 | 16,937 | |||||||||
| Property and equipment, net | 50,430 | 55,620 | |||||||||
| Operating right-of-use assets | 59,391 | 62,099 | |||||||||
| Restricted cash and cash equivalents, noncurrent | 6,944 | 6,963 | |||||||||
| Long-term investments | 475,016 | 314,575 | |||||||||
| Other assets | 24,647 | 24,699 | |||||||||
| TOTAL ASSETS | $ | 1,214,806 | $ | 1,002,823 | |||||||
| LIABILITIES AND STOCKHOLDERS’ EQUITY | |||||||||||
| CURRENT LIABILITIES: | |||||||||||
| Accounts payable | $ | 17,754 | $ | 9,803 | |||||||
| Accrued and other liabilities | 77,207 | 83,012 | |||||||||
| Total current liabilities | 94,961 | 92,815 | |||||||||
| Operating lease liabilities, noncurrent | 84,137 | 89,054 | |||||||||
| Contingent consideration obligation, noncurrent | 34,340 | 34,100 | |||||||||
| Other long-term liabilities | 18,875 | 21,578 | |||||||||
| TOTAL LIABILITIES | 232,313 | 237,547 | |||||||||
| Commitments and contingencies (Note 7) | |||||||||||
| STOCKHOLDERS’ EQUITY: | |||||||||||
Preferred stock, $0.0001 par value; 10,000,000 shares authorized as of June 30, 2026 and December 31, 2025; no shares issued and outstanding as of June 30, 2026 and December 31, 2025 | — | — | |||||||||
Common stock, $0.0001 par value; 300,000,000 shares authorized as of June 30, 2026 and December 31, 2025; 169,185,671 and 139,474,954 shares issued and outstanding as of June 30, 2026 and December 31, 2025, respectively | 17 | 14 | |||||||||
| Additional paid-in capital | 2,230,464 | 1,965,090 | |||||||||
| Accumulated other comprehensive loss | (4,602) | (2,057) | |||||||||
| Accumulated deficit | (1,243,386) | (1,197,771) | |||||||||
| TOTAL STOCKHOLDERS’ EQUITY | 982,493 | 765,276 | |||||||||
| TOTAL LIABILITIES AND STOCKHOLDERS’ EQUITY | $ | 1,214,806 | $ | 1,002,823 | |||||||
7
VIR BIOTECHNOLOGY, INC.
Condensed Consolidated Statements of Operations
(in thousands, except share and per share data)
(unaudited)
| Three Months Ended June 30, | |||||||||||
| 2026 | 2025 | ||||||||||
| Revenues: | |||||||||||
| License and collaboration revenue | $ | 238,935 | $ | (495) | |||||||
| Grant revenue | 11 | 183 | |||||||||
| Other revenue | — | 1,526 | |||||||||
| Total revenues | 238,946 | 1,214 | |||||||||
| Operating expenses: | |||||||||||
| Cost of revenue | — | 11 | |||||||||
| Research and development | 135,283 | 97,509 | |||||||||
| Selling, general and administrative | 30,196 | 22,283 | |||||||||
| Restructuring, long-lived assets impairment and related charges, net | — | (172) | |||||||||
| Total operating expenses | 165,479 | 119,631 | |||||||||
| Income (loss) from operations | 73,467 | (118,417) | |||||||||
| Other income: | |||||||||||
| Change in fair value of equity investments | (1,723) | (3,382) | |||||||||
| Interest income | 8,966 | 10,785 | |||||||||
| Other (expense) income, net | (451) | 226 | |||||||||
| Total other income | 6,792 | 7,629 | |||||||||
| Income (loss) before provision for income taxes | 80,259 | (110,788) | |||||||||
| Provision for income taxes | (179) | (170) | |||||||||
| Net income (loss) | $ | 80,080 | $ | (110,958) | |||||||
| Net income (loss) per share, basic | $ | 0.48 | $ | (0.80) | |||||||
| Net income (loss) per share, diluted | $ | 0.47 | $ | (0.80) | |||||||
| Weighted-average shares outstanding, basic | 167,719,015 | 138,447,469 | |||||||||
| Weighted-average shares outstanding, diluted | 168,879,127 | 138,447,469 | |||||||||
Media Contact
Caren Scannell
Director, Communications
cscannell@vir.bio
Investor Contact
Kiki Patel, PharmD
Head of Investor Relations
kpatel@vir.bio
8