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VolitionRx (NYSE: VNRX) grows 2025 revenue but discloses going concern risk

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(Moderate)
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Form Type
8-K

Rhea-AI Filing Summary

VolitionRx Limited reported full fiscal year 2025 revenue of $1.7 million, a 40% increase from the prior year, with Q4 revenue up 133% year over year. Operating expenses fell by $4.8 million, or 17%, and net loss decreased 14%, while net cash used in operating activities was $19.7 million, down 24%. The company highlighted its first order for Nu.Q® Cancer assays ahead of routine lung cancer use and participation of its Nu.Q® NETs assay in a government-backed sepsis program of approximately $7.3 million in France. After year-end, VolitionRx raised $5.4 million via at-the-market equity sales, $1.9 million from a convertible note and warrant, and received $1.0 million of non-dilutive funding, with about $0.9 million more expected over the next 12 months. The company also disclosed that its 2025 audited financial statements include an audit opinion with an explanatory paragraph about its ability to continue as a going concern.

Positive

  • Improving operating profile: 2025 revenue grew 40% to $1.7 million, Q4 revenue rose 133% year over year, operating expenses fell 17% ($4.8 million), and net cash used in operations declined 24% to $19.7 million, indicating better cost control and early commercial traction.

Negative

  • Going concern uncertainty: The 2025 audited financial statements include an audit opinion with an explanatory paragraph related to VolitionRx’s ability to continue as a going concern, underscoring ongoing losses, cash burn and reliance on external financing.

Insights

Strong growth and funding, but going concern risk remains.

VolitionRx showed improving trends in 2025: revenue rose 40% to $1.7 million, Q4 revenue grew 133% year over year, and operating expenses declined by $4.8 million or 17%. Net cash used in operations fell to $19.7 million, a 24% reduction.

To support operations, the company raised $5.4 million through an at-the-market equity facility, $1.9 million via a convertible note and warrant, and secured $1.0 million in non-dilutive regional funding, with about $0.9 million more expected over the next 12 months. These steps extend runway but indicate ongoing dependence on external financing.

A key concern is that the 2025 audited financial statements include an audit opinion with an explanatory paragraph about VolitionRx’s ability to continue as a going concern. This highlights persistent losses and cash burn despite progress in commercial traction and cost control. Future filings describing revenue scaling, licensing agreements and cash usage will be central to assessing the company’s financial trajectory.

2025 revenue $1.7 million Full-year 2025, 40% growth over previous year
Q4 revenue growth 133% Year-over-year increase for Q4 2025
Operating expense reduction $4.8 million (17%) Decrease in operating expenses versus prior year
Net loss change 14% decrease Net loss reduction for 2025 versus 2024
Net cash used in operations $19.7 million 2025 net cash used in operating activities, down 24%
ATM equity proceeds $5.4 million Net proceeds from equity sales after year-end
Convertible note and warrant proceeds $1.9 million Net proceeds from issuance after year-end
French sepsis program size $7.3 million Government-backed program including Nu.Q NETs assay
going concern financial
"includes an explanatory paragraph related to Volition’s ability to continue as a going concern"
A going concern is a business that is expected to continue its operations and meet its obligations for the foreseeable future, rather than shutting down or selling off assets. This assumption matters to investors because it indicates stability and ongoing profitability, making the business a more reliable investment. Think of it as believing a restaurant will stay open and serve customers, rather than closing down suddenly.
at-the-market facility financial
"received $5.4 million in net proceeds from equity sales through our at-the-market facility"
An at-the-market facility is a standing arrangement that lets a publicly traded company sell new shares directly into the open market at whatever the current market price is, typically through an investment bank acting as a sales agent. For investors it matters because it provides the company with a flexible way to raise cash without a large, one-time share offering; however, selling additional shares can dilute existing ownership and, by increasing supply, may pressure the stock price like adding more tickets to a limited-seat event.
convertible note financial
"$1.9 million in net proceeds from issuance of a convertible note and warrant"
A convertible note is a type of loan that a company gets from investors, which can later be turned into company shares instead of being paid back in cash. It matters because it helps startups raise money quickly without setting a fixed value for the company right away, making it easier to grow and attract investors.
epigenetics technical
"Volition, a multi-national epigenetics company, today announces financial results"
Epigenetics is the study of how environmental factors and experiences can influence how genes are turned on or off without changing the underlying genetic code. Think of it like a dimmer switch for a light, adjusting the brightness without altering the bulb itself. This process can affect health, behavior, and even how diseases develop, which is important for investors interested in long-term trends in medicine, wellness, and biotech industries.
forward-looking statements regulatory
"Statements in this press release may be “forward-looking statements” within the meaning of Section 27A"
Forward-looking statements are predictions or plans that companies share about what they expect to happen in the future, like estimating sales or profits. They matter because they help investors understand a company's outlook, but since they are based on guesses and assumptions, they can sometimes be wrong.
non-dilutive funding financial
"$1.0 million of non-dilutive funding from agencies of the Walloon Region"
Non-dilutive funding is money a company raises that does not require issuing new shares or reducing existing owners’ percentage ownership, such as grants, certain loans, contract revenue, or licensing deals. It matters to investors because it lets a company finance growth or research without shrinking shareholder stakes or changing control, much like topping up a car’s gas tank instead of selling part of the car to pay for the trip.
Revenue $1.7 million +40% year over year
Q4 revenue growth N/A +133% year over year
Operating expenses N/A -$4.8 million, -17% year over year
Net loss N/A -14% versus 2024
Net cash used in operations $19.7 million -24% year over year

EXHIBIT 99.1

 

VolitionRx Limited Announces Full Fiscal Year 2025 Financial Results and Business Update

 

Conference call to discuss financial and operational results scheduled for

 

Wednesday, April 1 at 8:30 a.m. U.S. Eastern Time

 

Henderson, Nevada, March 31, 2026 /PRNewswire/ -- VolitionRx Limited (NYSE AMERICAN: VNRX) (“Volition”), a multi-national epigenetics company, today announces financial results and a business update for the full fiscal year 2025. Volition management will host a conference call tomorrow, April 1 at 8:30 a.m. U.S. Eastern Time/2:30 p.m. Central European Time to discuss these results. Conference call details can be found below.

 

Cameron Reynolds, President and Group Chief Executive Officer, said:

 

“We set out over fifteen years ago to help save lives and improve outcomes for millions of patients worldwide, and I could not be prouder of the progress we are making towards that goal.

 

“In 2025 we not only received our first order for the Nu.Q® Cancer assays for clinical certification ahead of routine clinical use in lung cancer, but we also announced the inclusion of our Nu.Q® NETs assay in a real-world interventional evaluation of early detection of sepsis, in a government-backed program (~$7.3 million) in France.

 

“Cancer and sepsis are leading causes of death, accounting for approximately one third of deaths worldwide. Our tests are about to be used in both these devastating diseases, to help save lives in real world hospital settings: an extremely proud moment for our entire team.

 

“Our goal is to secure a range of licensing agreements in the human diagnostics space and to that end we are in discussions with around 10 of the world’s leading diagnostic and liquid biopsy companies and are at various stages of the process across our different pillars, ranging from due diligence to tech transfer, to evaluation of clinical samples, to contract negotiation. We anticipate further human licensing deals and will update on progress as they are completed.

 

“I believe we will look back on 2025, this first quarter of 2026 and indeed in time, the next few quarters, as transformational for the company.”

 

Financial Highlights

 

 

·

Finished the year strongly with year over year revenue growth for Q4 of 133%.

 

·

Full-year revenue for 2025 was $1.7 million, representing growth of 40% over the previous year.

 

·

Operating expenses for the year were down $4.8 million, or 17% compared to last year.

 

·

Net loss was down 14% for the year versus 2024.

 

·

Net cash used in operating activities was $19.7 million for the year, down 24%.

 

·

Subsequent to year end, we received:

 

$5.4 million in net proceeds from equity sales through our at-the-market facility,

 

$1.9 million in net proceeds from issuance of a convertible note and warrant, and

 

$1.0 million of non-dilutive funding from agencies of the Walloon Region, with an additional approximate $0.9 million expected to be received in tranches based on certain time and event milestones over the next 12 months.

 

 

 
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Event:

VolitionRx Limited Full Fiscal Year 2025 Earnings and Business Update Conference Call

Date:

Wednesday, April 1, 2026

Time:

8:30 a.m. U.S. Eastern Time/2:30 p.m. Central European Time

 

U.S. & Canada Dial-in: 1-877-407-9716 (toll free)

U.K. Dial-in: 0 800 756 3429 (toll free)

Toll/International: 1-201-493-6779

Conference ID: 13759627

 

Louise Batchelor, Group Chief Marketing & Communications Officer will host the call along with Cameron Reynolds, President and Group Chief Executive Officer of Volition, Terig Hughes, Group Chief Financial Officer, Dr. Andrew Retter, Medical Consultant and Dr. Jake Micallef, Chief Scientific Officer. The call will provide an update on important events that have taken place in 2025, subsequent events and upcoming milestones.

 

A live audio webcast of the conference call will also be available on this link. In addition, a telephone replay of the call will be available until April 15, 2026. The replay dial-in numbers are 1-844-512-2921 (toll-free) in the U.S. and Canada and 1-412-317-6671 (toll) internationally. Please use replay pin number 13759627.

 

About Volition

 

Volition is a multi-national company focused on advancing the science of epigenetics. Volition is dedicated to saving lives and improving outcomes for people and animals with life-altering diseases through earlier detection, as well as disease and treatment monitoring.

 

Through its subsidiaries, Volition is developing and commercializing simple, easy to use, cost-effective blood tests to help detect and monitor a range of diseases, including some cancers and diseases associated with NETosis, such as sepsis. Early detection and monitoring have the potential not only to prolong the life of patients, but also to improve their quality of life.

 

Volition’s research and development activities are centered in Belgium, with an innovation laboratory and office in the U.S. and an office in London.

 

The contents found at Volition’s website address are not incorporated by reference into this document and should not be considered part of this document. Such website address is included in this document as an inactive textual reference only.

 

Media Enquiries:

 

Louise Batchelor, Volition, mediarelations@volition.com +44 (0)7557 774620

 

 
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Safe Harbor Statement

 

Statements in this press release may be “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that concern matters that involve risks and uncertainties that could cause actual results to differ materially from those anticipated or projected in the forward-looking statements. Words such as “expects,” “anticipates,” “intends,” “plans,” “aims,” “targets,” “believes,” “seeks,” “estimates,” “optimizing,” “potential,” “goal,” “suggests,” “could,” “would,” “should,” “may,” “will” and similar expressions identify forward-looking statements. These forward-looking statements relate to, among other topics, Volition’s expectations related to revenue opportunities and growth, the receipt of funding based on certain milestones, the effectiveness and availability of Volition’s blood-based diagnostic, prognostic and disease monitoring tests, Volition’s ability to develop and successfully commercialize such test platforms for early detection of cancer and other diseases as well as serving as a diagnostic, prognostic or disease monitoring tools for such diseases, Volition’s expectations regarding future publications, Volition’s success in securing licensing and/or distribution agreements with third parties for its products, and Volition’s expectations regarding the terms of such agreements. Volition’s actual results may differ materially from those indicated in these forward-looking statements due to numerous risks and uncertainties, including, without limitation, results of studies testing the efficacy of its tests. For instance, if Volition fails to develop and commercialize diagnostic, prognostic or disease monitoring products, it may be unable to execute its plan of operations. Other risks and uncertainties include Volition’s failure to obtain necessary regulatory clearances or approvals to distribute and market future products; a failure by the marketplace to accept the products in Volition’s development pipeline or any other diagnostic, prognostic or disease monitoring products Volition might develop; Volition’s failure to secure adequate intellectual property protection; Volition will face fierce competition and Volition’s intended products may become obsolete due to the highly competitive nature of the diagnostics and disease monitoring market and its rapid technological change; downturns in domestic and foreign economies; and other risks, including those identified in Volition’s most recent Annual Report on Form 10-K and Quarterly Reports on Form 10-Q, as well as other documents that Volition files with the Securities and Exchange Commission. These statements are based on current expectations, estimates and projections about Volition’s business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Forward-looking statements are made as of the date of this release, and, except as required by law, Volition does not undertake an obligation to update its forward-looking statements to reflect future events or circumstances.

 

Pursuant to the disclosure requirements of the NYSE American Company Guide Section 610(b), Volition is reporting that its audited consolidated financial statements for the fiscal year ended December 31, 2025, included in Volition’s Annual Report on Form 10-K filed with the Securities and Exchange Commission on March 31, 2026, contains an audit opinion from its independent registered public accounting firm that includes an explanatory paragraph related to Volition’s ability to continue as a going concern. This announcement does not represent any change or amendment to Volition’s financial statements or to its Annual Report on Form 10-K for the fiscal year ended December 31, 2025.

 

Nucleosomics™, Capture-PCR™, Capture-Seq™ and Nu.Q® and their respective logos are trademarks and/or service marks of VolitionRx Limited and its subsidiaries. All other trademarks, service marks and trade names referred to in this press release are the property of their respective owners. Additionally, unless otherwise specified, all references to “$” refer to the legal currency of the United States of America.

 

 
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FAQ

How did VolitionRx (VNRX) perform financially in full year 2025?

VolitionRx reported 2025 revenue of $1.7 million, up 40% from the prior year. Q4 revenue grew 133% year over year. Operating expenses fell $4.8 million (17%), net loss declined 14%, and net cash used in operating activities was $19.7 million, down 24%.

What new funding did VolitionRx (VNRX) secure around its 2025 results?

Subsequent to year end, VolitionRx received $5.4 million in net proceeds from at-the-market equity sales, $1.9 million from a convertible note and warrant, and $1.0 million of non-dilutive funding, with an additional approximately $0.9 million expected over the next 12 months.

What operational milestones did VolitionRx (VNRX) highlight for cancer and sepsis?

VolitionRx received its first order for Nu.Q® Cancer assays for clinical certification before routine lung cancer use. It also announced inclusion of its Nu.Q® NETs assay in a real-world interventional evaluation of early sepsis detection in a government-backed French program of about $7.3 million.

Does VolitionRx’s 2025 report include a going concern warning?

Yes. VolitionRx stated that its audited consolidated financial statements for the year ended December 31, 2025 include an audit opinion with an explanatory paragraph about its ability to continue as a going concern, signaling material uncertainty about future financial viability.

What is VolitionRx’s strategy for human diagnostics licensing?

VolitionRx aims to secure a range of licensing agreements in human diagnostics. Management reports discussions with around 10 leading diagnostic and liquid biopsy companies, spanning due diligence, tech transfer, clinical sample evaluation and contract negotiation across its product pillars.

When is VolitionRx’s call to discuss 2025 results and what will it cover?

The company scheduled a conference call for Wednesday, April 1, 2026 at 8:30 a.m. U.S. Eastern Time. Management plans to discuss 2025 financial and operational results, subsequent events, and upcoming milestones, with replay and webcast access available for investors and stakeholders.

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