8-K: Vor Biopharma shares Exhibit 99.1 on Sjögren’s Phase 3 data

Rhea-AI Filing Summary

Vor Biopharma furnished a Regulation FD update via an 8-K. On October 28, 2025, the company hosted a webcast to discuss late‑breaking 48‑week Phase 3 clinical trial data from China for telitacicept in primary Sjögren’s disease. The presentation used in the webcast was furnished as Exhibit 99.1 and is not deemed filed under the Exchange Act.

8-K Event Classification

2 items: 7.01, 9.01

2 items

Item 7.01 Regulation FD Disclosure Disclosure

Material non-public information disclosed under Regulation Fair Disclosure, often investor presentations or guidance.

Item 9.01 Financial Statements and Exhibits Exhibits

Financial statements, pro forma financial information, and exhibit attachments filed with this report.

Understanding 8-K Material Events →

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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): October 28, 2025

VOR BIOPHARMA INC.

(Exact name of Registrant as Specified in Its Charter)

Delaware			001-39979	81-1591163
(State or Other Jurisdiction of Incorporation)			(Commission File Number)	(IRS Employer Identification No.)
500 Boylston Street, Suite 1350
Boston, Massachusetts				02116
(Address of Principal Executive Offices)				(Zip Code)

Registrant’s Telephone Number, Including Area Code: 617 655-6580

(Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class		Trading Symbol(s)		Name of each exchange on which registered
Common Stock, $0.0001 par value per share		VOR		Nasdaq Global Select Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company ☒

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 7.01 Regulation FD Disclosure.

On October 28, 2025, Vor Biopharma Inc. hosted a webcast to discuss late-breaking 48-week Phase 3 clinical trial data from China for telitacicept in primary Sjögren’s disease. A copy of the presentation used during the webcast is furnished as Exhibit 99.1.

The information contained in this Current Report on Form 8-K, including Exhibit 99.1, attached hereto, is being furnished and shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and shall not be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such filing.

Item 9.01 Financial Statements and Exhibits.

Exhibit No. Description

99.1 48-week Phase 3 Clinical Trial Data from China for Telitacicept in Primary Sjögren's Disease

104 Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

			Vor Biopharma Inc.
Date:	October 28, 2025	By:	/s/ Jean-Paul Kress
			Jean-Paul Kress Chief Executive Officer

FAQ

What did VOR disclose in this 8-K?

The company furnished a Regulation FD update about a webcast discussing 48‑week Phase 3 telitacicept data in primary Sjögren’s disease, with materials in Exhibit 99.1.

What is Exhibit 99.1 for VOR?

Exhibit 99.1 is the presentation used during the webcast covering 48‑week Phase 3 clinical data from China for telitacicept.

Is the information considered filed or furnished?

It is being furnished and shall not be deemed filed under the Exchange Act.

When was the webcast held?

October 28, 2025.

Which program was discussed by VOR?

Telitacicept in primary Sjögren’s disease, including late‑breaking 48‑week Phase 3 data from China.

Does this 8-K include financial results?

No, it provides a Regulation FD disclosure and the related presentation as Exhibit 99.1.