[Form 4] Vor Biopharma Inc. Insider Trading Activity

Rhea-AI Filing Summary

Vor Biopharma insiders sold a substantial block of common stock over three days. Reprogrammed Interchange LLC reported three dispositions totaling 1,263,647 shares sold in multiple trades at weighted-average prices of $1.9897, $2.0004 and $1.8151. Reported post-transaction beneficial holdings held by Reprogrammed decreased from 35,012,518 to 34,213,292 shares across the reported transactions. The filing notes these shares are held by Reprogrammed Interchange LLC and that Reid Hoffman may be deemed an indirect beneficial owner by virtue of shared control and pecuniary interest, while disclaiming beneficial ownership except to the extent of any pecuniary interest.

Positive

• Transparent disclosure of weighted-average sale prices and an offer to provide per-trade details upon request
• Clear statement identifying Reprogrammed Interchange LLC as the direct holder and describing Reid Hoffmans claimed status

Negative

• Sizable dispositions: a total of 1,263,647 shares sold across three days, which reduced reported beneficial holdings from 35,012,518 to 34,213,292
• No rationale provided for the sales in the filing (no mention of a trading plan or reason for the dispositions)

Insights

Securities Analyst

TL;DR: Insider group sold ~1.26M VOR shares over three days, reducing reported holdings—may pressure share supply.

The transactions show coordinated dispositions by Reprogrammed Interchange LLC across three consecutive trading dates, with weighted-average sale prices between $1.8151 and $2.0004. Total shares sold equal 1,263,647, a material absolute volume that modestly reduced reported beneficial holdings from 35.0M to 34.2M shares. While the filing provides weighted-average prices and offers to supply trade-level details on request, it does not explain the rationale for the sales. For investors, the activity increases share supply in the market and warrants monitoring of subsequent insider activity and any issuer disclosures explaining the sales.

Corporate Governance Expert

TL;DR: Disclosure is compliant and clear about indirect ownership and the reporting chain.

The Form 4 properly identifies Reprogrammed Interchange LLC as the direct holder and explains Reid Hoffmans potential indirect beneficial interest while including the customary disclaimer. The filing includes weighted-average prices and offers to provide per-trade detail to regulators or security holders, which supports transparency. There is no disclosure in the form about any 10b5-1 plan or other contractual trading instructions, so readers must rely on the forms facts alone.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Reprogrammed Interchange LLC

(Last) (First) (Middle)

101 MISSION STREET, SUITE 1000

(Street)

SAN FRANCISCO CA 94105

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Vor Biopharma Inc. [ VOR ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
09/08/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	09/08/2025		S		464,421	D	$1.9897(1)	35,012,518(2)	D
Common Stock	09/09/2025		S		449,226	D	$2.0004(3)	34,563,292(2)	D
Common Stock	09/10/2025		S		350,000	D	$1.8151(4)	34,213,292(2)	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person^*

Reprogrammed Interchange LLC

(Last) (First) (Middle)

101 MISSION STREET, SUITE 1000

(Street)

SAN FRANCISCO CA 94105

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Hoffman Reid

(Last) (First) (Middle)

101 MISSION STREET, SUITE 1000

(Street)

SAN FRANCISCO CA 94105

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

Explanation of Responses:

1. This transaction was executed in multiple trades at prices ranging from $1.97 to $2.01. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

2. The securities are held by Reprogrammed Interchange LLC ("Reprogrammed"). Reid Hoffman may be deemed a beneficial owner of securities held by Reprogrammed by virtue of his shared control over and indirect pecuniary interest in Reprogrammed. Mr. Hoffman disclaims beneficial ownership of the securities held by Reprogrammed, except to the extent of his pecuniary interest therein.

3. This transaction was executed in multiple trades at prices ranging from $1.97 to $2.03. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

4. This transaction was executed in multiple trades at prices ranging from $1.80 to $1.935. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

	/s/ Reid Hoffman	09/10/2025
	/s/ Frank Huang, Manager of Reprogrammed Interchange LLC	09/10/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

How many Vor Biopharma (VOR) shares were sold by the reporting parties?

The filing reports total dispositions of 1,263,647 shares sold across three transactions.

What were the weighted-average prices for the insider sales in the Form 4?

The weighted-average sale prices reported are $1.9897, $2.0004, and $1.8151 for the respective transactions.

Who holds the shares sold and what is Reid Hoffmans relationship to those shares?

The shares are held by Reprogrammed Interchange LLC; the filing states Reid Hoffman may be deemed an indirect beneficial owner due to shared control and pecuniary interest but disclaims beneficial ownership except to the extent of any pecuniary interest.

How did the reported beneficial ownership change after the transactions?

Reported beneficial ownership held by Reprogrammed decreased from 35,012,518 to 34,213,292 shares across the reported transactions.

Does the Form 4 state whether the sales were made under a Rule 10b5-1 plan?

The filing does not state that the transactions were made pursuant to a Rule 10b5-1 plan.