Vertex EVP disposes shares for tax withholding

Vertex Pharmaceuticals executive Duncan McKechnie reported a tax-related share disposition.

Rhea-AI Filing Summary

Vertex Pharmaceuticals executive Duncan McKechnie reported a tax-related share disposition. On this Form 4, he disposed of 2,283 shares of Vertex common stock on February 13, 2026 at an indicated price of $487.76 per share to cover tax obligations. After this transaction, he directly owned 19,528 shares.

Insider Trade Summary

Exercise Price or Tax Liability: 2,283 shares

Exercise Price or Tax Liability 1 txn

Insider McKechnie Duncan

Role EVP, Chief Commercial Officer

Type	Security	Shares	Price	Value
Exercise Price or Tax Liability	Common Stock	2,283	$487.76	$1.11M

Holdings After Transaction: Common Stock — 19,528 shares (Direct)

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What insider transaction did Vertex (VRTX) report for Duncan McKechnie?

Vertex EVP and Chief Commercial Officer Duncan McKechnie reported a tax-related share disposition. He delivered 2,283 shares of Vertex common stock to satisfy tax obligations, as indicated by code F, rather than executing an open-market sale of shares.

How many Vertex (VRTX) shares did Duncan McKechnie dispose of?

Duncan McKechnie disposed of 2,283 shares of Vertex common stock. The transaction was coded F, meaning the shares were delivered to cover an exercise price or tax liability, not as a typical open-market sale transaction of company stock.

At what price were Duncan McKechnie’s Vertex (VRTX) shares valued in this Form 4?

The 2,283 Vertex common shares were reported at a transaction price of $487.76 per share. This price is used for reporting the value of the tax-withholding disposition and does not necessarily represent an independently negotiated market sale price.

How many Vertex (VRTX) shares does Duncan McKechnie own after this transaction?

After the reported tax-withholding disposition, Duncan McKechnie directly owns 19,528 shares of Vertex common stock. This post-transaction balance reflects his remaining direct holdings following the delivery of 2,283 shares to satisfy tax-related obligations.

What does transaction code F mean in the Vertex (VRTX) Form 4?

Transaction code F indicates payment of an exercise price or tax liability by delivering securities. For Duncan McKechnie’s Vertex transaction, it shows that 2,283 shares were disposed of to satisfy tax obligations, rather than being sold in a standard open-market stock transaction.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 02/18/2026 - 04:37 PM Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

McKechnie Duncan

(Last) (First) (Middle)

C/O VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

(Street)

BOSTON MA 02210

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
VERTEX PHARMACEUTICALS INC / MA [ VRTX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	EVP, Chief Commercial Officer

3. Date of Earliest Transaction (Month/Day/Year)
02/13/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	02/13/2026		F		2,283	D	$487.76	19,528	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

Remarks:

	/s/ Christiana Stevenson, Attorney-in-Fact	02/18/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.