Welcome to our dedicated page for Vistagen Therapeutics SEC filings (Ticker: VTGN), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Vistagen Therapeutics, Inc. (Nasdaq: VTGN) SEC filings page on Stock Titan provides access to the company’s regulatory disclosures as filed with the U.S. Securities and Exchange Commission. Vistagen is a Nevada-incorporated, late clinical-stage biopharmaceutical company headquartered in South San Francisco, California, and its filings offer detailed insight into its nose-to-brain neurocircuitry platform, pherine pipeline, governance, and financial condition.
Through documents such as Form 10-K annual reports and Form 10-Q quarterly reports, readers can review Vistagen’s descriptions of its business as a neuroscience-focused biopharmaceutical company, its intranasal pherine product candidates, and the risks and uncertainties associated with late-stage clinical development. These filings also discuss the company’s focus on indications including social anxiety disorder, major depressive disorder, and vasomotor symptoms (hot flashes) due to menopause, as well as other women’s health conditions.
Current reports on Form 8-K provide timely information on material events, including clinical and corporate milestones. Recent 8-K filings have addressed topics such as financial results for specific fiscal quarters, progress in the PALISADE Phase 3 program for fasedienol in social anxiety disorder, and changes in executive leadership and board composition. Proxy materials on Form DEF 14A describe matters submitted to a shareholder vote, including director elections, advisory votes on executive compensation, and auditor ratification, along with details about governance practices.
Stock Titan’s platform enhances these filings with AI-powered summaries that highlight key points from lengthy documents, helping users quickly understand complex sections on clinical programs, compensation, and shareholder matters. Real-time updates from EDGAR ensure that new Vistagen filings, including any future Forms 4 reporting insider equity awards or transactions, appear promptly, while AI-generated overviews can assist in interpreting how each filing relates to the company’s pherine development strategy and late-stage clinical status.
Vistagen Therapeutics, Inc. reported a board change. On March 17, 2026, Mary Rotunno resigned from the company’s Board of Directors, with her resignation effective April 1, 2026. The filing does not describe any related changes to executive management or company operations.
Vistagen Therapeutics, Inc. furnished an investor presentation outlining its intranasal “pherine” pipeline, which targets nose‑to‑brain neurocircuitry for neurological and psychiatric disorders. The company highlights five clinical‑stage product candidates and emphasizes rapid onset, non‑systemic delivery and favorable safety in completed studies.
The presentation focuses on fasedienol for acute treatment of social anxiety disorder, including a Phase 3 PALISADE‑2 trial that met its primary endpoint on the Subjective Units of Distress Scale and an ongoing Phase 3 PALISADE‑4 study. It also describes positive Phase 2a data for itruvone in major depressive disorder and refisolone for menopausal hot flashes and premenstrual dysphoric disorder, along with early‑stage programs PH15 for psychomotor/cognitive impairment due to mental fatigue and PH284 for cancer cachexia.
Vistagen Therapeutics, Inc. reported that its board approved a reduction of its workforce by approximately 20%. The company states this step is intended to support disciplined cash management while focusing resources on ongoing clinical studies in its PALISADE Program for fasedienol in social anxiety disorder.
Vistagen expects topline results from its PALISADE-4 Phase 3 trial in the first half of 2026 and currently anticipates its cash runway extending into 2027. Affected employees may receive cash severance and temporary healthcare coverage if they are eligible, elect coverage, and sign a separation agreement with a general release of claims. The company expects associated costs to be immaterial but notes additional costs could arise.
Vistagen Therapeutics, Inc. reported that on February 13, 2026, board member Paul Edick resigned from its Board of Directors. The company did not provide additional details about the circumstances of his resignation.
The company stated that it is actively seeking new candidates to fill the resulting vacancy on the Board, indicating its intention to maintain a full board composition.
OrbiMed Advisors LLC and OrbiMed Capital LLC report significant ownership stakes in Vistagen Therapeutics, Inc. common stock. OrbiMed Advisors reports beneficial ownership of 1,420,300 shares, or 3.6% of the class, while OrbiMed Capital reports 1,639,700 shares, or 4.2% of the class. Together, the reporting persons hold 7.8% of Vistagen’s common stock on behalf of other persons entitled to dividends or sale proceeds. Voting and investment power are exercised through a management committee of Carl L. Gordon, Sven H. Borho and W. Carter Neild, each of whom disclaims beneficial ownership. The securities are stated to be held in the ordinary course of business and not for the purpose of changing or influencing control of the issuer.
Commodore Capital and affiliates reported a 9.9% beneficial stake in Vistagen Therapeutics, Inc. common stock on a passive Schedule 13G/A filing. As of December 31, 2025, they may be deemed to beneficially own 4,383,508 shares through Tranche 1 and Tranche 2 warrants and a pre-funded warrant, all subject to a 9.99% beneficial ownership limitation. The report attributes investment discretion to Commodore Capital LP as manager of Commodore Capital Master LP, with managing partners Robert Egen Atkinson and Michael Kramarz. The filers certify the holdings are not for changing or influencing control of Vistagen.
Great Point Partners, LLC, Dr. Jeffrey R. Jay and Ms. Lillian Nordahl jointly report beneficial ownership of 2,055,834 shares of Vistagen Therapeutics common stock, representing 4.95% of the class as of the event date.
The stake is held entirely through warrants to purchase 2,055,834 shares, with shared voting and dispositive power and no sole power. The warrants include a 9.99% beneficial ownership cap, and the filers certify the securities are not held to change or influence control of Vistagen.
Janus Henderson Group plc filed an amended Schedule 13G reporting that it beneficially owns 0 shares of Vistagen Therapeutics, Inc. common stock, representing 0.0% of the class as of 12/31/2025. The filing shows Janus Henderson and its affiliated asset managers have no sole or shared voting or dispositive power over Vistagen shares.
The asset manager subsidiaries exercise investment discretion on behalf of various managed portfolios, which receive all dividends and sale proceeds from securities in their accounts, but none of these portfolios own more than five percent of Vistagen’s common stock. Janus Henderson certifies that any securities were held in the ordinary course of business and not to influence control of Vistagen.
Vistagen Therapeutics, Inc. is the subject of an amended Schedule 13G filing in which StemPoint Capital LP, StemPoint Capital Management GP LLC, and Michelle Ross report beneficial ownership of 616,749 shares of common stock issuable upon exercise of warrants, representing 1.5% of the class.
The percentage is calculated using 39,495,451 shares outstanding as of November 12, 2025, plus the shares underlying these warrants. The warrants are subject to a 9.9% beneficial ownership limitation, and all voting and dispositive power over the 616,749 underlying shares is reported as shared among the reporting persons.
Vistagen Therapeutics, Inc. received an updated ownership report from Nantahala Capital Management, LLC and its managing members Wilmot B. Harkey and Daniel Mack. As of December 31, 2025, they may be deemed to beneficially own 1,953,045 shares of common stock, representing 4.71% of the class.
All 1,953,045 shares are reported with shared voting and shared dispositive power, and no sole voting or dispositive power. The reporting group states the shares were acquired and are held in the ordinary course of business, without the purpose or effect of changing or influencing control of Vistagen.