STOCK TITAN

Yarrow Bioscience, Inc. (VYNE) holders report 8,816,429 pre-funded warrants

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Form Type
3

Rhea-AI Filing Summary

RTW Fund Group GP, LLC and Roderick Wong, M.D., reported as ten percent owners of Yarrow Bioscience, Inc., disclose indirect holdings received in a July 27, 2026 merger: 399,597 shares of common stock and pre-funded warrants exercisable at $0.0001 for 8,816,429 shares, subject to a 9.99% beneficial ownership cap. The securities are held by an affiliated entity managed by RTW Fund Group, and the reporting persons disclaim beneficial ownership except to the extent of their pecuniary interest.

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Insider RTW Fund Group GP, LLC, WONG RODERICK
Role 10% Owner | 10% Owner
Type Security Shares Price Value
holding Pre-Funded Warrants (Right to Buy) F4, F5, F3 -- -- --
holding Common Stock F1, F2, F3 -- -- --
Holdings After Transaction: Pre-Funded Warrants (Right to Buy) — 8,816,429 shares (Indirect, See footnote); Common Stock — 399,597 shares (Indirect, See footnote)
Footnotes (5)
  1. F1. Effective as of July 27, 2026 (the "Effective Time"), a wholly owned subsidiary of VYNE Therapeutics Inc. ("VYNE") merged with and into Yarrow Bioscience, Inc. ("Yarrow") with Yarrow continuing as a wholly owned subsidiary of VYNE and the surviving corporation of the merger (the "Merger") under the name "Yarrow Bioscience Operating Company Corp." In connection with the completion of the Merger, VYNE changed its name to "Yarrow Bioscience, Inc." (hereinafter, the "Issuer").
  2. F2. Represents the number of shares of common stock, par value $0.0001, of the Issuer ("Issuer Common Stock") received by the Reporting Person in the Merger in exchange for the shares of common stock of Yarrow ("Yarrow Common Stock") held by the Reporting Person prior to the Merger. Each share of Yarrow Common Stock held at the Effective Time was exchanged for 0.7171 shares of Issuer Common Stock.
  3. F3. Held by a certain affiliated entity managed by RTW Fund Group GP, LLC ("RTW Fund Group"). Roderick Wong, M.D. serves as the Managing Member of RTW Fund Group. The Reporting Persons disclaim beneficial ownership of the reported securities for purposes of Section 16 under the Securities Exchange Act of 1934, as amended, except to the extent of their pecuniary interest therein.
  4. F4. The pre-funded warrants to purchase shares of Issuer Common Stock (the "Issuer Pre-Funded Warrants") have no expiration date and are exercisable at any time after the date of issuance. A holder of Issuer Pre-Funded Warrants may not exercise the Issuer Pre-Funded Warrant if the holder, together with its affiliates, would beneficially own more than 9.99% of the number of shares of common stock outstanding immediately after giving effect to such exercise.
  5. F5. Represents the number of Issuer Pre-Funded Warrants received by the Reporting Person in the Merger in exchange for pre-funded warrants to purchase shares of Yarrow Common Stock (the "Yarrow Pre-Funded Warrants") held by the Reporting Person prior to the Merger. Each Yarrow Pre-Funded Warrant held at the Effective Time was exchanged for 0.7171 Issuer Pre-Funded Warrants.
Common Stock Held 399,597 shares Indirect holdings of Issuer Common Stock following the merger effective July 27, 2026
Pre-Funded Warrants Underlying Shares 8,816,429 shares Indirectly held Issuer Pre-Funded Warrants, each exercisable into one share of Common Stock
Pre-Funded Warrant Exercise Price $0.0001 per share Exercise price of Issuer Pre-Funded Warrants
Exchange Ratio – Common Stock 0.7171 Each share of Yarrow Common Stock exchanged for 0.7171 share of Issuer Common Stock in the merger
Exchange Ratio – Pre-Funded Warrants 0.7171 Each Yarrow Pre-Funded Warrant exchanged for 0.7171 Issuer Pre-Funded Warrant
Beneficial Ownership Limitation 9.99% Maximum beneficial ownership permitted upon exercise of Issuer Pre-Funded Warrants
Effective Time of Merger July 27, 2026 Date when a VYNE subsidiary merged with Yarrow and VYNE was renamed Yarrow Bioscience, Inc.
Pre-Funded Warrants financial
"The pre-funded warrants to purchase shares of Issuer Common Stock"
Pre-funded warrants are financial instruments that give investors the right to purchase a company's stock at a set price, but with most or all of the purchase price paid upfront. They function like a coupon or gift card for stock, allowing investors to buy shares later at a fixed price, which can be beneficial if they want to avoid future price increases. This makes them important for investors seeking flexibility and certainty in their investment plans.
Effective Time regulatory
"Effective as of July 27, 2026 (the Effective Time), a wholly owned subsidiary"
The exact clock time when a regulatory filing, approval, or corporate action formally becomes legally active; from that moment the change is binding and can be acted on. Investors care because the effective time marks when ownership, rights, trading rules, or new securities take effect — like a light switch turning on a contract or transaction — which determines when risks, benefits and market reactions begin.
beneficially own regulatory
"would beneficially own more than 9.99% of the number of shares"
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
pecuniary interest regulatory
"except to the extent of their pecuniary interest therein"
wholly owned subsidiary financial
"a wholly owned subsidiary of VYNE Therapeutics Inc. merged with and into Yarrow"
A wholly owned subsidiary is a company whose entire ownership is held by another company (the parent), so the parent controls decisions, operations, and finances. Think of it as a fully controlled branch that runs as its own legal entity but whose results flow straight into the parent’s financial statements; investors watch these structures because they affect consolidated revenue, risk exposure, and how profits, liabilities, and cash flow are allocated across the corporate group.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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FAQ

What holdings are reported for VYNE (Yarrow Bioscience) by RTW Fund Group and Roderick Wong?

They report indirect stakes in Yarrow Bioscience consisting of 399,597 common shares and pre-funded warrants exercisable into 8,816,429 common shares. These positions reflect securities received in a merger completed on July 27, 2026.

How many pre-funded warrants linked to VYNE (Yarrow Bioscience) are disclosed?

The insiders disclose pre-funded warrants exercisable for 8,816,429 shares of Yarrow Bioscience common stock. These warrants carry a $0.0001 exercise price per share and are subject to a 9.99% beneficial ownership limitation on exercise.

What common stock position in Yarrow Bioscience (VYNE) is shown in this insider report?

The report shows an indirect position of 399,597 shares of Yarrow Bioscience common stock. These shares were received in exchange for Yarrow Bioscience, Inc. common shares in a merger using a 0.7171-for-1 exchange ratio.

How did the VYNE and Yarrow Bioscience merger affect these insider holdings?

At the July 27, 2026 Effective Time, Yarrow merged into a VYNE subsidiary, and VYNE was renamed Yarrow Bioscience, Inc. Each Yarrow common share and pre-funded warrant converted into Issuer securities at a 0.7171 exchange ratio, creating the reported positions.

Do RTW Fund Group and Roderick Wong claim full beneficial ownership of the Yarrow Bioscience securities?

No. The securities are held by an affiliated entity managed by RTW Fund Group, and the reporting persons disclaim beneficial ownership for Section 16 purposes except to the extent of their pecuniary interest in those securities.
SEC Form 3
FORM 3UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0104
Estimated average burden
hours per response:0.5
1. Name and Address of Reporting Person*
RTW Fund Group GP, LLC

(Last)(First)(Middle)
40 10TH AVENUE, FLOOR 7

(Street)
NEW YORK NEW YORK 10014

(City)(State)(Zip)

UNITED STATES

(Country)
2. Date of Event Requiring Statement (Month/Day/Year)
07/27/2026
3. Issuer Name and Ticker or Trading Symbol
Yarrow Bioscience, Inc. [ YARW ]
3a. Foreign Trading Symbol
5. If Amendment, Date of Original Filed (Month/Day/Year)
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
DirectorX10% Owner
Officer (give title below)Other (specify below)
6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
XForm filed by More than One Reporting Person
Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock399,597(1)(2)ISee footnote(3)
Table II - Derivative Securities Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4) 2. Date Exercisable and Expiration Date (Month/Day/Year)3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 6. Nature of Indirect Beneficial Ownership (Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Pre-Funded Warrants (Right to Buy) (4) (4)Common Stock8,816,429(5)$0.0001ISee footnote(3)
1. Name and Address of Reporting Person*
RTW Fund Group GP, LLC

(Last)(First)(Middle)
40 10TH AVENUE, FLOOR 7

(Street)
NEW YORK NEW YORK 10014

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
DirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
WONG RODERICK

(Last)(First)(Middle)
40 10TH AVENUE, FLOOR 7

(Street)
NEW YORK NEW YORK 10014

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
DirectorX10% Owner
Officer (give title below)Other (specify below)
Explanation of Responses:
1. Effective as of July 27, 2026 (the "Effective Time"), a wholly owned subsidiary of VYNE Therapeutics Inc. ("VYNE") merged with and into Yarrow Bioscience, Inc. ("Yarrow") with Yarrow continuing as a wholly owned subsidiary of VYNE and the surviving corporation of the merger (the "Merger") under the name "Yarrow Bioscience Operating Company Corp." In connection with the completion of the Merger, VYNE changed its name to "Yarrow Bioscience, Inc." (hereinafter, the "Issuer").
2. Represents the number of shares of common stock, par value $0.0001, of the Issuer ("Issuer Common Stock") received by the Reporting Person in the Merger in exchange for the shares of common stock of Yarrow ("Yarrow Common Stock") held by the Reporting Person prior to the Merger. Each share of Yarrow Common Stock held at the Effective Time was exchanged for 0.7171 shares of Issuer Common Stock.
3. Held by a certain affiliated entity managed by RTW Fund Group GP, LLC ("RTW Fund Group"). Roderick Wong, M.D. serves as the Managing Member of RTW Fund Group. The Reporting Persons disclaim beneficial ownership of the reported securities for purposes of Section 16 under the Securities Exchange Act of 1934, as amended, except to the extent of their pecuniary interest therein.
4. The pre-funded warrants to purchase shares of Issuer Common Stock (the "Issuer Pre-Funded Warrants") have no expiration date and are exercisable at any time after the date of issuance. A holder of Issuer Pre-Funded Warrants may not exercise the Issuer Pre-Funded Warrant if the holder, together with its affiliates, would beneficially own more than 9.99% of the number of shares of common stock outstanding immediately after giving effect to such exercise.
5. Represents the number of Issuer Pre-Funded Warrants received by the Reporting Person in the Merger in exchange for pre-funded warrants to purchase shares of Yarrow Common Stock (the "Yarrow Pre-Funded Warrants") held by the Reporting Person prior to the Merger. Each Yarrow Pre-Funded Warrant held at the Effective Time was exchanged for 0.7171 Issuer Pre-Funded Warrants.
/s/ Roderick Wong, for RTW Fund Group GP, LLC By: Roderick Wong, M.D., Managing Member07/30/2026
/s/ Roderick Wong By: Roderick Wong, M.D.07/30/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 3: SEC 1473 (03-26)