STOCK TITAN

Casdin fund adds 200,000 GeneDx (WGS) shares in open-market buys

Filing Impact
(Very High)
Filing Sentiment
(Very Positive)
Form Type
4

Rhea-AI Filing Summary

GeneDx Holdings Corp. reported an insider-related increase in holdings by entities associated with Casdin Capital. Casdin Partners Master Fund, L.P. made open-market purchases of 150,000 Class A common shares at $56.4449 per share on June 4, 2026 and 50,000 shares at $52.8566 per share on June 5, 2026, totaling 200,000 shares. After these trades, the Master Fund held 3,707,164 shares indirectly. Additional positions as of June 4, 2026 included 333,144 shares owned by the Master Fund, 19,247 shares owned by the GP entity, and 20,517 shares owned directly by Eli Casdin, each as separate holdings.

Positive

  • None.

Negative

  • None.
Insider Casdin Capital, LLC, Casdin Eli, Casdin Partners Master Fund, L.P., Casdin Partners GP, LLC
Role null | null | null | null
Bought 200,000 shs ($11.11M)
Type Security Shares Price Value
Purchase Class A Common Stock, par value $0.0001 per share 50,000 $52.8566 $2.64M
Purchase Class A Common Stock, par value $0.0001 per share 150,000 $56.4449 $8.47M
holding Class A Common Stock, par value $0.0001 per share -- -- --
holding Class A Common Stock, par value $0.0001 per share -- -- --
holding Class A Common Stock, par value $0.0001 per share -- -- --
Holdings After Transaction: Class A Common Stock, par value $0.0001 per share — 3,707,164 shares (Indirect, See footnote); Class A Common Stock, par value $0.0001 per share — 20,517 shares (Direct, null)
Footnotes (1)
  1. The securities are owned directly by the Casdin Partners Master Fund, L.P. (the "Master Fund") and may be deemed to be indirectly beneficially owned by (i) Casdin Capital, LLC, the investment adviser to the Master Fund ("Casdin"), (ii) Casdin Partners GP, LLC, the general partner of the Master Fund (the "GP"), and (iii) Eli Casdin, the managing member of Casdin and the GP. The securities are owned directly by Eli Casdin. The securities are owned directly by the GP and may be deemed to be indirectly beneficially owned by Eli Casdin, the managing member of the GP. The securities are owned directly by CMLS Holdings LLC ("CMLS Holdings"). The Board of Managers of CMLS Holdings includes Eli Casdin, who, as a member of the Board of Managers of CMLS Holdings, shares voting and investment discretion with respect to the common stock held by CMLS Holdings.
Open-market purchase (June 4, 2026) 150,000 shares at $56.4449/share Non-derivative Class A common stock buy by Master Fund
Open-market purchase (June 5, 2026) 50,000 shares at $52.8566/share Additional non-derivative Class A common stock buy
Master Fund holding after trades 3,707,164 shares Total Class A common shares indirectly held post-purchases
GP entity holding 19,247 shares Class A common shares owned directly by Casdin Partners GP, LLC
Direct holding by Eli Casdin 20,517 shares Class A common shares owned directly as of June 4, 2026
Additional Master Fund position 333,144 shares Separate Class A common stock holding as of June 4, 2026
open-market purchase financial
"transaction_action: "open-market purchase" for non-derivative common stock"
An open-market purchase is when an investor or a company buys shares on a public stock exchange at the going market price, rather than through a private deal. It matters to investors because these purchases change how many shares are available, can push the stock price up or signal confidence from large buyers, and often affect per-share metrics like earnings—think of it like someone buying lots of apples off a grocery shelf, reducing supply and potentially raising the price.
indirect ownership financial
"direct_or_indirect: "I" and nature_of_ownership: "See footnote""
beneficially owned financial
"may be deemed to be indirectly beneficially owned by (i) Casdin Capital, LLC"
Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.
ten percent owner financial
"reporting person flags include is_ten_percent_owner: 1 for each entity"
Class A Common Stock financial
"security_title: "Class A Common Stock, par value $0.0001 per share""
Class A common stock is a category of a company’s shares that carries a specific set of ownership rights—most commonly defined voting power and claims on dividends—set out in the company’s charter. For investors it matters because the class determines how much influence you have over corporate decisions, the share’s likely dividend and trading behavior, and how it compares in value to other share classes, like choosing a particular seat with different privileges at the company’s decision-making table.
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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Casdin Capital, LLC

(Last)(First)(Middle)
1350 AVENUE OF THE AMERICAS
SUITE 2600

(Street)
NEW YORK NEW YORK 10019

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
GeneDx Holdings Corp. [ WGS ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirectorX10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/04/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
XForm filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Class A Common Stock, par value $0.0001 per share06/04/2026P150,000A$56.44493,657,164ISee footnote(1)
Class A Common Stock, par value $0.0001 per share06/05/2026P50,000A$52.85663,707,164ISee footnote(1)
Class A Common Stock, par value $0.0001 per share20,517D(2)
Class A Common Stock, par value $0.0001 per share19,247ISee footnote(3)
Class A Common Stock, par value $0.0001 per share333,144ISee footnote(4)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
1. Name and Address of Reporting Person*
Casdin Capital, LLC

(Last)(First)(Middle)
1350 AVENUE OF THE AMERICAS
SUITE 2600

(Street)
NEW YORK NEW YORK 10019

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
Casdin Eli

(Last)(First)(Middle)
1350 AVENUE OF THE AMERICAS
SUITE 2600

(Street)
NEW YORK NEW YORK 10019

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
Casdin Partners Master Fund, L.P.

(Last)(First)(Middle)
1350 AVENUE OF THE AMERICAS
SUITE 2600

(Street)
NEW YORK NEW YORK 10019

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
Casdin Partners GP, LLC

(Last)(First)(Middle)
1350 AVENUE OF THE AMERICAS
SUITE 2600

(Street)
NEW YORK NEW YORK 10019

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)Other (specify below)
Explanation of Responses:
1. The securities are owned directly by the Casdin Partners Master Fund, L.P. (the "Master Fund") and may be deemed to be indirectly beneficially owned by (i) Casdin Capital, LLC, the investment adviser to the Master Fund ("Casdin"), (ii) Casdin Partners GP, LLC, the general partner of the Master Fund (the "GP"), and (iii) Eli Casdin, the managing member of Casdin and the GP.
2. The securities are owned directly by Eli Casdin.
3. The securities are owned directly by the GP and may be deemed to be indirectly beneficially owned by Eli Casdin, the managing member of the GP.
4. The securities are owned directly by CMLS Holdings LLC ("CMLS Holdings"). The Board of Managers of CMLS Holdings includes Eli Casdin, who, as a member of the Board of Managers of CMLS Holdings, shares voting and investment discretion with respect to the common stock held by CMLS Holdings.
Remarks:
Each Reporting Person disclaims beneficial ownership in the securities reported on this Form 4 except to the extent of its pecuniary interest, if any, therein, and this report shall not be deemed to be an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.
Casdin Partners Master Fund, LP, By: Casdin Partners GP, LLC, its General Partner, By: /s/ Eli Casdin, Managing Member06/08/2026
Casdin Capital LLC, By: /s/ Eli Casdin Managing Member06/08/2026
Casdin Partners GP LLC, By: /s/ Eli Casdin Managing Member, /s/ Eli Casdin, Eli Casdin06/08/2026
/s/ Eli Casdin, Eli Casdin06/08/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

At what prices were the new GeneDx (WGS) shares purchased by the Casdin fund?

The Master Fund bought 150,000 GeneDx Class A shares at $56.4449 per share and 50,000 shares at $52.8566 per share. These transactions were classified as open-market purchases of non-derivative common stock in the Form 4.

How many GeneDx (WGS) shares did Casdin Partners Master Fund hold after the transactions?

Following the reported open-market purchases, Casdin Partners Master Fund, L.P. held 3,707,164 GeneDx Class A common shares indirectly. This post-transaction holding reflects the cumulative position associated with the Master Fund after buying the additional 200,000 shares.

Which entities are associated with the GeneDx (WGS) insider holdings in this Form 4?

Holdings are reported for Casdin Partners Master Fund, L.P., Casdin Capital, LLC, Casdin Partners GP, LLC, and Eli Casdin. Footnotes state the Master Fund owns certain shares directly, with other entities and Eli Casdin deemed to have indirect beneficial ownership relationships.

Are the GeneDx (WGS) insider trades classified as derivative or non-derivative?

The reported insider trades are non-derivative transactions in GeneDx Class A common stock. Both purchases are labeled as open-market or private transaction purchases, with no associated options, warrants, or other derivative securities listed in the transaction data.