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Annovis Bio, Inc. (ANVS) Financials

ANVS
FY2025 annual
Revenue $0 YoY not available
Net Income -$28.9M -17.3% YoY
EPS (Diluted) -$1.40 YoY not available
Operating Cash Flow -$25.6M -17.0% YoY
Market Cap $42.4M as of Oct 17, 2026
Price / Sales n/m revenue is not positive, FY2025
Price / Earnings n/m net loss, so no earnings multiple, FY2025
Price / Book n/m negative shareholder equity, so no book multiple, Q2 FY2026

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Oct 17, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q2 FY2026, filed Aug 14, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the ANVS SEC filings page.

Annovis Bio, Inc. (ANVS) reported $0 in revenue for fiscal year 2025. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 7 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ANVS FY2025

Annovis remains a development-stage business: research spending drives losses, while external financing—not operations—funds balance-sheet expansion.

In FY2025, operating cash flow of -$25.6M tracked the net loss of $28.9M, showing that reported losses are translating into cash use rather than mainly reflecting non-cash charges. Meanwhile, financing cash flow of $34.6M exceeded operating cash use and helped total assets increase between FY2024 and FY2025, so the balance sheet is being rebuilt through capital raised outside operations.

R&D was $25.2M against an operating loss of $29.7M in FY2025, making development spending the dominant disclosed driver of losses. The operating loss narrowed from $45.0M in FY2023 to $29.7M in FY2025 even as R&D remained substantial, indicating that spending intensity—not revenue scale—is determining reported results.

Capitalization strengthened without comparable liability growth: liabilities edged lower between FY2024 and FY2025 while equity rose materially. The reported liquidity comparison equaled 9.1 months of the latest annual operating outflow, while the financing inflow shows that this position depended on funding activity rather than internally generated cash.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Financial health score not available

Annovis Bio, Inc. does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.

Piotroski F-Score Partial
2/6

Annovis Bio, Inc. passes 2 of 6 computable financial strength tests (3 of the nine could not be computed from available data). 2 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), neither operating efficiency signal passes.

Earnings Quality No Cash Backing
N/A

Annovis Bio, Inc. reported a net loss of $28.9M while operations used $25.6M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Net Income
-$14.8M
YoY-138.3%
QoQ+15.8%

Annovis Bio, Inc. reported -$14.8M in net income in Q2 2026. This represents a decrease of 138.3% from the same quarter a year earlier. Against the prior quarter it is up 15.8%.

EPS (Diluted)
-$0.40
QoQ+36.5%

Annovis Bio, Inc. earned -$0.40 per diluted share (EPS) in Q2 2026. Against the prior quarter it is up 36.5%.

Revenue

Not reported for Q2 2026.

EBITDA

Not reported for Q2 2026.

Cash & Balance Sheet

Cash & Debt
$18.7M
YoY+9.3%
QoQ+31.7%
5Y CAGR-17.6%

Annovis Bio, Inc. held $18.7M in cash as of Q2 2026; long-term debt is not reported for that period.

Shares Outstanding
43M
QoQ+23.0%
5Y CAGR+39.4%

Annovis Bio, Inc. had 43M shares outstanding in Q2 2026. Against the prior quarter it is up 23.0%.

Free Cash Flow

Not reported for Q2 2026.

Dividends Per Share

Not reported for Q2 2026.

Margins & Returns

None of these metrics is reported for Q2 2026.

Capital Allocation

R&D Spending
$12.0M
YoY+132.6%
QoQ-28.2%

Annovis Bio, Inc. invested $12.0M in research and development in Q2 2026. This represents an increase of 132.6% from the same quarter a year earlier. Against the prior quarter it is down 28.2%.

Share Buybacks

Not reported for Q2 2026.

Capital Expenditures

Not reported for Q2 2026.

ANVS Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ANVS quarterly income statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
RevenueN/A$0N/AN/AN/A$0N/AN/A
R&D Expenses$12.0M+132.6%$16.7M+233.6%N/A$6.3M+133.9%$5.2M-10.8%$5.0M-23.1%N/A$2.7M-80.6%
SG&A Expenses$2.4M+113.6%$1.3M+1.6%N/A$1.1M-32.6%$1.1M-43.9%$1.3M-1.8%N/A$1.7M+65.6%
Operating Income-$14.4M-129.3%-$18.0M-186.7%N/A-$7.4M-69.5%-$6.3M+19.2%-$6.3M+19.6%N/A-$4.4M+70.5%
Income Tax$0$0N/A$0$0$0N/A$0
Net Income-$14.8M-138.3%-$17.6M-218.0%N/A-$7.3M+42.5%-$6.2M-23.9%-$5.5M-419.0%N/A-$12.6M+14.1%
EPS (Basic)-$0.40-25.0%-$0.63-96.9%-$0.39-2.6%-$0.37+61.9%-$0.32+27.3%-$0.32-220.0%-$0.38+83.7%-$0.97+40.5%
EPS (Diluted)-$0.40-$0.63-$0.39+7.1%-$0.37-$0.32-$0.32-$0.42+82.0%-$0.97+40.5%
Diluted Shares (Avg)38M28MN/A20M19M17MN/A13M+44.0%

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, EBITDA, Interest Expense.

ANVS Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ANVS quarterly balance sheet
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Total Assets$22.0M+2.7%$16.2M-39.2%$21.1M+51.4%$17.2M+19.7%$21.5M+325.1%$26.7M+242.2%$13.9M+36.4%$14.4M+40.5%
Cash & Equivalents$18.7M+9.3%$14.2M-36.1%$19.5M+85.1%$15.3M+21.0%$17.1M+328.5%$22.2M+608.8%$10.6M+83.4%$12.6M+98.8%
Short-Term Investments$0$0$0$0$0$0$0$0
Long-Term Investments$0$0$0$0$0$0$0$0
Total Liabilities$26.3M+741.6%$13.1M+388.9%$4.2M-8.4%$4.0M-44.7%$3.1M-54.0%$2.7M-76.0%$4.6M-74.3%$7.3M+104.7%
Current Liabilities$6.4M+126.7%$12.8M+410.7%$3.6M-6.3%$3.7M-30.7%$2.8M-30.9%$2.5M-48.6%$3.9M-9.3%$5.4M+51.2%
Non-Current Liabilities$19.9M+6148.6%$327K+82.7%$595K-19.3%$299K-84.3%$319K-88.4%$179K-97.2%$737K-94.6%$1.9M
Total Equity-$4.3M-123.2%$3.1M-87.0%$16.9M+81.0%$13.2M+86.3%$18.3M+1146.9%$24.1M+817.2%$9.3M+220.1%$7.1M+6.1%
Retained Earnings-$196.1M-33.8%-$181.3M-29.2%-$163.7M-21.4%-$153.9M-19.3%-$146.6M-26.0%-$140.4M-26.1%-$134.8M-22.3%-$129.0M-46.5%

Not reported in any period shown, so not listed: Current Assets, Inventory, Accounts Receivable, Goodwill, Long-Term Debt.

ANVS Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ANVS quarterly cash flow statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Cash Flow-$21.9M-329.2%-$9.0M-11.3%-$8.9M-7.7%-$3.5M-8.9%-$5.1M-51.3%-$8.1M-15.2%-$8.3M+11.5%-$3.2M+65.8%
Stock-Based Compensation$1.6M+223.9%$183K-63.4%N/A$445K+13.1%$497K-68.9%$500K+37.0%N/A$393K-37.8%
Financing Cash Flow$26.4M$3.7M-81.3%$13.2M+112.4%$1.6M-86.1%$0-100.0%$19.8M+348.1%$6.2M-29.3%$11.8M

Not reported in any period shown, so not listed: Depreciation & Amortization, Capital Expenditures, Free Cash Flow, Investing Cash Flow, Dividends Paid, Share Buybacks.

ANVS Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ANVS quarterly financial ratios
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Return on EquityN/A-563.2%-540.2ppN/A-55.2%+123.7pp-33.9%-23.0%N/A-178.9%+42.1pp
Return on Assets-67.3%-38.3pp-108.4%-87.7ppN/A-42.3%+45.8pp-29.0%+70.5pp-20.7%-7.1ppN/A-88.0%+56.0pp
Debt-to-EquityN/A4.20+4.1x0.25-0.2x0.31-0.7x0.170.110.501.03+0.5x
Asset TurnoverN/A0.000.0xN/AN/AN/A0.000.0xN/AN/A

Not reported in any period shown, so not listed: Gross Margin, Operating Margin, Net Margin, Current Ratio, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
Annovis Bio, Inc. ANVS FY2025 $0 -$28.9M N/A $42.4M —
Barinthus Biotherapeutics plc American BRNS FY2025 $0 -$66.4M N/A $30.2M —
Radiopharm Theranostics Limited RADX FY2025 $3.6M -$38.3M N/A $15.0M 20/100
Tempest Therapeutics, Inc. TPST FY2025 N/A -$26.3M N/A $10.5M —
Verrica Pharmaceuticals Inc. VRCA FY2025 $35.6M -$17.9M -50.3% $61.8M 68/100
PLUS THERAPEUTICS, Inc. PSTV FY2025 $5.2M -$22.4M N/A $26.6M 32/100

Frequently Asked Questions

What is Annovis Bio, Inc.'s annual revenue?

Annovis Bio, Inc. (ANVS) reported $0 in total revenue for fiscal year 2025. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Is Annovis Bio, Inc. profitable?

No, Annovis Bio, Inc. (ANVS) reported a net income of -$28.9M in fiscal year 2025.

What is Annovis Bio, Inc.'s earnings per share (EPS)?

Annovis Bio, Inc. (ANVS) reported diluted earnings per share of -$1.40 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Annovis Bio, Inc. (ANVS) has a return on equity of -171.2% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Annovis Bio, Inc. (ANVS) recorded an outflow of $25.6M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Annovis Bio, Inc. (ANVS) had $21.1M in total assets as of fiscal year 2025, including both current and long-term assets.

Annovis Bio, Inc. (ANVS) invested $25.2M in research and development during fiscal year 2025.

Annovis Bio, Inc. (ANVS) had 28M shares outstanding as of fiscal year 2025.

Annovis Bio, Inc. (ANVS) had a debt-to-equity ratio of 0.25 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Annovis Bio, Inc. (ANVS) had a return on assets of -136.9% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Annovis Bio, Inc. (ANVS) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (FY2025). The market capitalization is $42.4M as of Oct 17, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

Annovis Bio, Inc. (ANVS) has no price-to-sales ratio at the moment: revenue is not positive (FY2025). The market capitalization is $42.4M as of Oct 17, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

At the end of fiscal year 2025, Annovis Bio, Inc. (ANVS) held $19.5M in cash, cash equivalents and investments, and reported an operating cash outflow of $25.6M over that year. Dividing the one by the other, the reported balance equals about 9 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Annovis Bio, Inc. (ANVS) has a Piotroski F-Score of 2 out of 6 computable signals; 3 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Annovis Bio, Inc. (ANVS) reported a net loss of $28.9M while operations used $25.6M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

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