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Plus Therapeutics Inc Financials

PSTV
FY2025 annual
Revenue $5.2M -10.5% YoY
Net Income -$22.4M -72.5% YoY
EPS (Diluted) -$0.29 YoY not available
Free Cash Flow -$20.8M -94.8% YoY
Source SEC Filings (10-K/10-Q) Data as of Jun 30, 2026 Currency USD FYE December

Plus Therapeutics Inc (PSTV) reported $5.2M in revenue for fiscal year 2025, down 10.5% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 15 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI PSTV FY2025

Development spending remains larger than sales, while financing inflows—not operations—drive the latest balance-sheet repair.

The near match between FY2025 net loss of $22.4M and operating cash flow of -$20.8M indicates that reported losses are largely cash-based, not mainly non-cash accounting effects. Free cash flow nearly matched operating cash flow despite just $67K of capital expenditure, making day-to-day operations—not reinvestment—the dominant cash drain.

FY2025 R&D of $8.4M exceeded revenue of $5.2M, a development-stage spending pattern that leaves commercialization behind the cost base. Revenue slipped from $5.8M in FY2024 to $5.2M in FY2025, so scale has not yet become the operating engine.

Equity moved from -$8.9M to $4.0M between FY2024 and FY2025, a material equity recovery. That interpretation is reinforced by $30.3M of financing cash flow and a 1.2x current ratio: balance-sheet improvement came with financing activity rather than operating cash generation.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 32 / 100
Financial Health Score 32/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Plus Therapeutics Inc's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
0

Not available for Plus Therapeutics Inc, and counted as zero in the overall score.

Dilution
44
R&D Intensity
72
Revenue Progress
52
Burn Trend
23
Balance Sheet
0

Not available for Plus Therapeutics Inc, and counted as zero in the overall score.

Altman Z-Score Distress
-45.51

Plus Therapeutics Inc scores -45.51, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($26.6M) relative to total liabilities ($12.3M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
4/7

Plus Therapeutics Inc passes 4 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 2 of 4 profitability signals pass, all 2 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality No Cash Backing
N/A

Plus Therapeutics Inc reported a net loss of $22.4M while operations used $20.8M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Plus Therapeutics Inc reported an operating loss of $15.3M against $548K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

Revenue
$5.2M
YoY-10.5%

Plus Therapeutics Inc generated $5.2M in revenue in fiscal year 2025. This represents a decrease of 10.5% from the prior year.

EBITDA
-$14.9M
YoY-7.5%

Plus Therapeutics Inc's EBITDA was -$14.9M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 7.5% from the prior year.

Net Income
-$22.4M
YoY-72.5%

Plus Therapeutics Inc reported -$22.4M in net income in fiscal year 2025. This represents a decrease of 72.5% from the prior year.

EPS (Diluted)
-$0.29

Plus Therapeutics Inc earned -$0.29 per diluted share (EPS) in fiscal year 2025.

Cash & Balance Sheet

Free Cash Flow
-$20.8M
YoY-94.8%

Plus Therapeutics Inc recorded an outflow of $20.8M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents a decrease of 94.8% from the prior year.

Cash & Debt
$4.3M
YoY+5500.0%
5Y CAGR-12.6%
10Y CAGR-11.4%

Plus Therapeutics Inc held $4.3M in cash as of fiscal year 2025; long-term debt is not reported for that period.

Shares Outstanding
6M

Plus Therapeutics Inc had 6M shares outstanding in fiscal year 2025.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Return on Equity
-560.2%

Plus Therapeutics Inc's ROE was -560.2% in fiscal year 2025, measuring profit generated per dollar of shareholder equity.

Gross Margin

Not reported for fiscal year 2025.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$8.4M
YoY-20.8%
5Y CAGR+25.4%
10Y CAGR-7.9%

Plus Therapeutics Inc invested $8.4M in research and development in fiscal year 2025. This represents a decrease of 20.8% from the prior year.

Capital Expenditures
$67K
YoY-54.1%

Plus Therapeutics Inc invested $67K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 54.1% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

PSTV Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

PSTV annual income statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Revenue$4.2M$5.2M-10.5%$5.8M+18.5%$4.9MN/AN/AN/AN/A$3.7M+36.5%$2.7M-42.2%$4.7M-3.8%$4.8M-2.3%$5.0M-30.5%$7.1M-18.2%$8.7M+9.1%$8.0M
Cost of RevenueN/AN/AN/AN/AN/AN/AN/AN/A$1.1M-12.9%$1.3M-51.5%$2.7M-14.8%$3.2M+8.4%$2.9M-14.1%$3.4M-14.5%$4.0M+4.2%$3.8M
Gross ProfitN/AN/AN/AN/AN/AN/AN/AN/A$2.5M+1628.1%$146K-92.5%$1.9M+17.5%$1.7M-17.9%$2.0M-45.6%$3.7M-21.4%$4.7M+13.6%$4.1M
R&D Expenses$12.5M$8.4M-20.8%$10.6M+9.2%$9.7M-0.1%$9.7M+82.2%$5.3M+97.1%$2.7M-49.7%$5.4M-2.9%$5.5M+8.9%$5.1M-68.7%$16.2M-14.8%$19.0M+25.8%$15.1M-11.5%$17.1M+25.2%$13.6M+25.0%$10.9M
SG&A Expenses$18.1M$12.1M+22.1%$9.9M+16.3%$8.5M-16.5%$10.2M+49.4%$6.9M+7.0%$6.4M+21.1%$5.3M-5.2%$5.6M-16.7%$6.7M-21.8%$8.6M-12.3%$9.8M-38.8%$16.0M-0.5%$16.0M+2.3%$15.7M+6.4%$14.7M
Operating Income-$26.4M-$15.3M-4.1%-$14.7M-10.3%-$13.3M+32.4%-$19.7M-57.8%-$12.5M-30.3%-$9.6M-162.1%-$3.7M+58.3%-$8.8M+20.9%-$11.1M+43.8%-$19.7M-28.9%-$15.3M+52.9%-$32.4M-5.7%-$30.7M-8.0%-$28.4M+3.4%-$29.4M
Interest ExpenseN/A$548K+206.1%$179K-54.7%$395K-44.4%$711K-23.7%$932K-15.8%$1.1M-40.3%$1.9M-3.5%$1.9M-6.2%$2.0M-20.9%$2.6M-23.3%$3.4M-22.7%$4.4M+28.7%$3.4M+0.3%$3.4M+21.6%$2.8M
Income TaxN/A$0$0$0$0$0$0$0$0$0$0$0N/AN/AN/AN/A
Net Income-$26.1M-$22.4M-72.5%-$13.0M+2.5%-$13.3M+34.3%-$20.3M-51.3%-$13.4M-62.6%-$8.2M+24.3%-$10.9M+13.8%-$12.6M+44.3%-$22.7M-2.9%-$22.0M-17.6%-$18.7M+49.8%-$37.4M-42.8%-$26.2M+18.9%-$32.3M+0.5%-$32.5M
EPS (Diluted)-$0.29-$2.34-$4.24-$11.58-$1.11N/AN/AN/AN/AN/AN/AN/AN/AN/A-$0.61

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

PSTV Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

PSTV annual balance sheet
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Total Assets$16.3M+146.1%$6.6M-41.8%$11.4M-52.3%$23.9M+8.6%$22.0M+81.6%$12.1M-47.9%$23.2M-3.2%$24.0M-24.1%$31.6M-8.7%$34.6M-8.2%$37.7M-2.6%$38.7M-7.9%$42.1M-2.8%$43.3M-16.1%$51.5M
Current Assets$15.2M+188.5%$5.3M-46.5%$9.8M-54.9%$21.8M+10.6%$19.7M+115.0%$9.2M-53.7%$19.8M+105.5%$9.6M-35.1%$14.9M-20.7%$18.7M-11.7%$21.2M-2.0%$21.7M-11.8%$24.6M-27.7%$34.0M-21.6%$43.3M
Cash & Equivalents$4.3M+5500.0%$76K-99.1%$8.6M-52.8%$18.1M-1.5%$18.4M+120.5%$8.3M-52.4%$17.6M+233.6%$5.3M-44.9%$9.6M-24.2%$12.6M-12.1%$14.3M-1.9%$14.6M-5.7%$15.5M-39.7%$25.7M-30.3%$36.9M
InventoryN/AN/AN/AN/AN/AN/A$107K0.0%$107K0.0%$107K-97.1%$3.7M-13.3%$4.3M-11.0%$4.8M+30.7%$3.7M+16.3%$3.2M-4.3%$3.3M
Accounts ReceivableN/AN/AN/AN/AN/A$0-100.0%$1.2M+556.7%$178K+36.9%$130K-89.5%$1.2M+18.1%$1.1M-15.4%$1.2M-70.1%$4.2M+5.8%$3.9M+73.7%$2.3M
Goodwill$372K0.0%$372K0.0%$372K0.0%$372K0.0%$372K0.0%$372K0.0%$372K0.0%$372K0.0%$372K-90.5%$3.9M0.0%$3.9M0.0%$3.9M0.0%$3.9M0.0%$3.9M0.0%$3.9M
Total Liabilities$12.3M-20.9%$15.6M+22.3%$12.7M-26.9%$17.4M+56.3%$11.1M+22.8%$9.1M-58.9%$22.1M+17.6%$18.8M+0.8%$18.6M-21.2%$23.6M-7.3%$25.5M-42.6%$44.4M+14.1%$38.9M+5.8%$36.8M-11.5%$41.6M
Current Liabilities$12.3M-20.8%$15.6M+45.0%$10.7M-9.5%$11.9M+101.9%$5.9M-31.3%$8.5M-41.1%$14.5M-17.5%$17.6M-4.6%$18.4M+47.3%$12.5M+48.2%$8.4M-47.0%$15.9M+6.8%$14.9M-15.4%$17.6M+125.2%$7.8M
Long-Term DebtN/AN/AN/A$3.8M-24.4%$5.0MN/AN/AN/A$0-100.0%$11.0M-34.0%$16.7M-7.5%$18.0M-21.9%$23.1M+79.0%$12.9M-41.2%$22.0M
Total Equity$4.0M+144.7%-$8.9M-563.9%-$1.3M-120.9%$6.4M-40.5%$10.8M+257.5%$3.0M+161.3%$1.2M-77.8%$5.2M-59.8%$13.0M+18.3%$11.0M-10.0%$12.2M+314.1%-$5.7M-282.1%$3.1M-51.5%$6.5M-35.1%$9.9M
Retained Earnings-$515.9M-4.5%-$493.5M-2.7%-$480.5M-2.9%-$467.2M-4.5%-$446.9M-3.1%-$433.5M-1.9%-$425.3M-2.6%-$414.4M-3.1%-$401.7M-6.0%-$379.1M-6.2%-$357.0M-5.5%-$338.3M-12.4%-$300.9M-9.5%-$274.7M-13.3%-$242.4M

PSTV Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

PSTV annual cash flow statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Operating Cash Flow-$22.2M-$20.8M-96.8%-$10.6M+17.9%-$12.9M+0.9%-$13.0M-26.2%-$10.3M-21.9%-$8.4M-42.8%-$5.9M+50.7%-$12.0M+33.9%-$18.1M+7.2%-$19.5M+4.6%-$20.5M+32.5%-$30.3M+12.2%-$34.6M-7.4%-$32.2M+8.9%-$35.3M
Capital Expenditures$1.4M$67K-54.1%$146K-8.8%$160KN/AN/AN/A$67K-49.6%$133K-54.9%$295K+340.3%$67K-89.0%$611K-20.0%$764K+47.2%$519K-56.9%$1.2M+115.0%$560K
Free Cash Flow-$23.5M-$20.8M-94.8%-$10.7M+17.8%-$13.0MN/AN/AN/A-$6.0M+50.7%-$12.1M+34.3%-$18.4M+6.0%-$19.6M+7.0%-$21.1M+32.2%-$31.1M+11.4%-$35.1M-5.0%-$33.4M+6.9%-$35.9M
Investing Cash Flow-$2.9M-$854K+79.2%-$4.1M-2469.4%-$160K+78.9%-$759K-825.6%-$82K+83.4%-$493K-108.9%$5.6M+4288.0%-$133K+90.4%-$1.4MN/AN/A-$1.3M-136.4%$3.7M+406.1%-$1.2M-115.0%-$560K
Financing Cash Flow$25.3M$30.3M+389.9%$6.2M+79.6%$3.4M-74.4%$13.5M-34.1%$20.4M+6500.0%-$319K-102.5%$12.6M+76.2%$7.2M-57.4%$16.8MN/AN/AN/A$20.8M-6.4%$22.2M+10.2%$20.1M
Share BuybacksN/AN/A$374K+196.8%$126KN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A

Not reported in any period shown, so not listed: Dividends Paid.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

PSTV Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

PSTV annual financial ratios
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Gross MarginN/AN/AN/AN/AN/AN/AN/A68.7%+63.3pp5.4%-36.3pp41.7%+7.5pp34.2%-6.5pp40.6%-11.3pp52.0%-2.1pp54.1%+2.1pp51.9%
Operating Margin-293.5%-252.3%-271.1%N/AN/AN/AN/A-238.7%-412.0%-423.2%-316.0%-654.9%-430.8%-326.3%-368.4%
Net Margin-429.4%-222.8%-271.0%N/AN/AN/AN/A-344.2%-843.7%-473.5%-387.4%-754.5%-367.6%-370.6%-406.5%
Return on Equity-560.2%N/AN/A-314.6%-190.9pp-123.6%+148.2pp-271.9%+666.6pp-938.5%-696.7pp-241.8%-67.3pp-174.5%+26.2pp-200.7%-47.1pp-153.6%N/A-835.8%-335.7pp-500.1%-173.8pp-326.3%
Return on Assets-137.1%+58.5pp-195.7%-78.7pp-116.9%-32.0pp-85.0%-24.0pp-61.0%+7.1pp-68.1%-21.2pp-46.9%+5.8pp-52.7%+19.1pp-71.8%-8.1pp-63.7%-14.0pp-49.7%+46.8pp-96.5%-34.3pp-62.2%+12.4pp-74.6%-11.7pp-63.0%
Current Ratio1.23+0.9x0.34-0.6x0.92-0.9x1.84-1.5x3.36+2.3x1.07-0.3x1.37+0.8x0.55-0.3x0.81-0.7x1.50-1.0x2.52+1.2x1.36-0.3x1.65-0.3x1.93-3.6x5.54
Debt-to-Equity3.09N/AN/A0.59+0.1x0.46-2.5x2.99-16.0x19.02+15.4x3.59+3.6x0.00-1.0x1.00-0.4x1.37N/A7.38+5.4x2.00-0.2x2.21
FCF Margin-399.8%-183.7%-264.8%N/AN/AN/AN/A-329.8%-685.1%-421.0%-435.7%-627.8%-492.6%-383.5%-449.5%

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

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Frequently Asked Questions

What is Plus Therapeutics Inc's annual revenue?

Plus Therapeutics Inc (PSTV) reported $5.2M in total revenue for fiscal year 2025. This represents a -10.5% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Plus Therapeutics Inc's revenue growing?

Plus Therapeutics Inc (PSTV) revenue declined by 10.5% year-over-year, from $5.8M to $5.2M in fiscal year 2025.

Is Plus Therapeutics Inc profitable?

No, Plus Therapeutics Inc (PSTV) reported a net income of -$22.4M in fiscal year 2025.

Plus Therapeutics Inc (PSTV) reported diluted earnings per share of -$0.29 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Plus Therapeutics Inc (PSTV) had EBITDA of -$14.9M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Plus Therapeutics Inc (PSTV) has a return on equity of -560.2% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Plus Therapeutics Inc (PSTV) recorded an outflow of $20.8M in free cash flow during fiscal year 2025. This represents a -94.8% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Plus Therapeutics Inc (PSTV) recorded an outflow of $20.8M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Plus Therapeutics Inc (PSTV) had $16.3M in total assets as of fiscal year 2025, including both current and long-term assets.

Plus Therapeutics Inc (PSTV) invested $67K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Plus Therapeutics Inc (PSTV) invested $8.4M in research and development during fiscal year 2025.

Plus Therapeutics Inc (PSTV) had 6M shares outstanding as of fiscal year 2025.

Plus Therapeutics Inc (PSTV) had a current ratio of 1.23 as of fiscal year 2025, which is considered adequate.

Plus Therapeutics Inc (PSTV) had a debt-to-equity ratio of 3.09 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Plus Therapeutics Inc (PSTV) had a return on assets of -137.1% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Plus Therapeutics Inc (PSTV) has an Altman Z-Score of -45.51, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Plus Therapeutics Inc (PSTV) has a Piotroski F-Score of 4 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Plus Therapeutics Inc (PSTV) reported a net loss of $22.4M while operations used $20.8M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Plus Therapeutics Inc (PSTV) reported an operating loss of $15.3M against $548K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Plus Therapeutics Inc (PSTV) scores 32 out of 100 on our Financial Health Score, indicating weak standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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