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PLUS THERAPEUTICS, Inc. (PSTV) Financials

PSTV
Trailing 12 months to June 30, 2026
Revenue $4.2M -21.0% YoY
Net Income -$26.1M -37.1% YoY
EPS (Diluted) -$0.29 FY2025 annual
Free Cash Flow -$23.5M -39.4% YoY
Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q2 FY2026, filed Aug 14, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the PSTV SEC filings page.

PLUS THERAPEUTICS, Inc. (PSTV) reported $4.2M in revenue over the twelve months to Jun 30, 2026, down 21.0% from the prior twelve months. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 15 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI PSTV FY2025

Plus Therapeutics remains a development-stage business: R&D exceeds revenue, operating cash outflows widened, and financing rebuilt equity in FY2025.

Revenue slipped from $5.8M in FY2024 to $5.2M in FY2025 while R&D also fell. Operating cash outflow nevertheless nearly doubled, reaching $20.8M; that divergence means FY2025 cash needs were not explained by the reported R&D budget alone.

The company’s financing-dependent structure is visible in FY2025: financing provided $30.3M while operating activities consumed $20.8M. That inflow helped restore positive equity of $4.0M from negative equity in FY2024, so the balance-sheet improvement came chiefly from financing rather than operating earnings.

R&D intensity remains high: spending was $8.4M against FY2025 revenue of $5.2M. Operating losses were -252.3% of revenue in FY2024 and -293.5% in FY2025, showing that the expense base remains far above current commercial scale.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 32 / 100
Financial Health Score 32/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of PLUS THERAPEUTICS, Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
0

Not available for PLUS THERAPEUTICS, Inc., and counted as zero in the overall score.

Dilution
46

PLUS THERAPEUTICS, Inc. had 6M shares outstanding at the end of fiscal year 2025. Dilution ranks emerging companies on how fast that count has grown over three years, where a slower rise is the better one, and PLUS THERAPEUTICS, Inc. scores 46/100 among other emerging companies.

R&D Intensity
72

PLUS THERAPEUTICS, Inc. spent $8.4M on research and development in fiscal year 2025, which was 40.9% of its operating costs that year. R&D Intensity ranks emerging companies on the share of operating costs that goes into research, and PLUS THERAPEUTICS, Inc. scores 72/100 among other emerging companies.

Revenue Progress
47

PLUS THERAPEUTICS, Inc. reported revenue of $5.2M in fiscal year 2025, against $5.8M in fiscal year 2024. Revenue Progress ranks emerging companies on the three-year path of that line, and PLUS THERAPEUTICS, Inc. scores 47/100 among other emerging companies.

Burn Trend
25

PLUS THERAPEUTICS, Inc.'s operations used $20.8M of cash in fiscal year 2025, against $10.6M used in fiscal year 2024. Burn Trend ranks emerging companies on which way that figure has moved over three years, and PLUS THERAPEUTICS, Inc. scores 25/100 among other emerging companies.

Balance Sheet
0

Not available for PLUS THERAPEUTICS, Inc., and counted as zero in the overall score.

Altman Z-Score Distress
-45.51

PLUS THERAPEUTICS, Inc. scores -45.51, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($26.6M) relative to total liabilities ($12.3M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
4/7

PLUS THERAPEUTICS, Inc. passes 4 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 2 of 4 profitability signals pass, all 2 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality No Cash Backing
N/A

PLUS THERAPEUTICS, Inc. reported a net loss of $22.4M while operations used $20.8M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

PLUS THERAPEUTICS, Inc. reported an operating loss of $15.3M against $548K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

Revenue
$411K
YoY-70.4%
QoQ-60.0%

PLUS THERAPEUTICS, Inc. generated $411K in revenue in Q2 2026. This represents a decrease of 70.4% from the same quarter a year earlier. Against the prior quarter it is down 60.0%.

Net Income
-$9.0M
YoY-274.8%
QoQ-29.7%

PLUS THERAPEUTICS, Inc. reported -$9.0M in net income in Q2 2026. This represents a decrease of 274.8% from the same quarter a year earlier. Against the prior quarter it is down 29.7%.

EPS (Diluted)
-$1.31
YoY-718.8%

PLUS THERAPEUTICS, Inc. earned -$1.31 per diluted share (EPS) in Q2 2026. This represents a decrease of 718.8% from the same quarter a year earlier.

EBITDA

Not reported for Q2 2026.

Cash & Balance Sheet

Free Cash Flow
-$7.6M
YoY-31.5%
QoQ-8.1%

PLUS THERAPEUTICS, Inc. recorded an outflow of $7.6M in free cash flow in Q2 2026, representing a cash shortfall after capex. This represents a decrease of 31.5% from the same quarter a year earlier. Against the prior quarter it is down 8.1%.

Cash & Debt
$2.4M
YoY+6.0%
QoQ-21.7%
5Y CAGR-32.7%
10Y CAGR-19.2%

PLUS THERAPEUTICS, Inc. held $2.4M in cash as of Q2 2026; long-term debt is not reported for that period.

Shares Outstanding
8M
YoY-76.8%
5Y CAGR-8.9%
10Y CAGR-9.5%

PLUS THERAPEUTICS, Inc. had 8M shares outstanding in Q2 2026. This represents a decrease of 76.8% from the same quarter a year earlier.

Dividends Per Share

Not reported for Q2 2026.

Margins & Returns

Return on Equity
-164.8%
YoY-334.6pp
QoQ-106.8pp

PLUS THERAPEUTICS, Inc.'s ROE was -164.8% in Q2 2026, measuring profit generated per dollar of shareholder equity. This is down 334.6 percentage points from the same quarter a year earlier. Against the prior quarter it is down 106.8 percentage points.

Gross Margin

Not reported for Q2 2026.

Operating Margin

Not shown for Q2 2026: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for Q2 2026: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$4.3M
YoY+242.3%
QoQ+48.9%

PLUS THERAPEUTICS, Inc. invested $4.3M in research and development in Q2 2026. This represents an increase of 242.3% from the same quarter a year earlier. Against the prior quarter it is up 48.9%.

Capital Expenditures
$499K
YoY+7028.6%
QoQ-39.0%

PLUS THERAPEUTICS, Inc. invested $499K in capex in Q2 2026, funding long-term assets and infrastructure. This represents an increase of 7028.6% from the same quarter a year earlier. Against the prior quarter it is down 39.0%.

Share Buybacks

Not reported for Q2 2026.

PSTV Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

PSTV quarterly income statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Revenue$411K-70.4%$1.0M-2.9%$1.4M-3.2%$1.4M-4.1%$1.4M+8.7%$1.1M-36.9%$1.4M$1.5M
R&D Expenses$4.3M+242.3%$2.9M+63.2%$2.9M+34.5%$2.4M-14.8%$1.2M-55.1%$1.8M-36.4%$2.2M$2.9M+14.6%
SG&A Expenses$5.2M+209.3%$5.3M+86.1%$4.2M+33.3%$3.4M+43.6%$1.7M-23.6%$2.8M+28.3%$3.1M$2.4M+20.0%
Operating Income-$9.1M-488.9%-$7.1M-101.3%-$5.7M-47.2%-$4.5M-18.0%-$1.5M+58.4%-$3.5M-7.2%-$3.9M-$3.8M-16.9%
EBITDAN/A-$7.0M-107.2%N/AN/AN/A-$3.4M-7.8%N/AN/A
Interest Expense$5K$17K-96.9%N/AN/AN/A$548K+1511.8%$57K$61K-29.9%
Net Income-$9.0M-274.8%-$6.9M+60.1%-$5.7M-46.4%-$4.4M-53.9%$5.2M+275.2%-$17.4M-433.6%-$3.9M-$2.9M+10.7%
EPS (Basic)-$1.31-311.3%-$1.05+96.5%N/A-$0.04+89.2%$0.62+237.8%-$29.86-3881.3%N/A-$0.37+63.0%
EPS (Diluted)-$1.31-718.8%-$1.05N/A-$0.04-$0.16-$29.86N/A-$0.37
Diluted Shares (Avg)7M-17.5%7MN/A107M8M582,668N/A8M

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, Income Tax.

PSTV Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

PSTV quarterly balance sheet
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Total Assets$14.0M+35.6%$19.9M+65.2%$16.3M+146.1%$18.7M+167.6%$10.3M-7.7%$12.1M+114.5%$6.6M-41.8%$7.0M-47.4%
Current Assets$11.8M+27.8%$18.0M+65.9%$15.2M+188.5%$17.6M+227.9%$9.2M-1.8%$10.9M+158.0%$5.3M-46.5%$5.4M-53.7%
Cash & Equivalents$2.4M+6.0%$3.0M-69.4%$4.3M+5500.0%$13.3M+986.6%$2.2M-54.5%$9.9M+240.1%$76K-99.1%$1.2M-88.9%
Goodwill$372K0.0%$372K0.0%$372K0.0%$372K0.0%$372K0.0%$372K0.0%$372K0.0%$372K0.0%
Total Liabilities$8.6M+17.1%$8.0M-77.7%$12.3M-20.9%$13.6M+12.0%$7.3M-61.2%$35.7M+241.3%$15.6M+22.3%$12.2M+14.0%
Current Liabilities$8.6M+17.1%$8.0M-24.7%$12.3M-20.8%$13.6M+12.4%$7.3M-61.1%$10.6M+1.5%$15.6M+45.0%$12.1M+14.9%
Non-Current Liabilities$0$0-100.0%$15K-51.6%$0-100.0%$0-100.0%$25.1M+42506.8%$31K-98.5%$40K-66.1%
Total Equity$5.5M+80.1%$12.0M+150.6%$4.0M+144.7%$5.1M+197.7%$3.0M+139.8%-$23.6M-388.8%-$8.9M-563.9%-$5.2M-297.3%
Retained Earnings-$531.8M-5.2%-$522.8M-2.3%-$515.9M-4.5%-$510.2M-4.2%-$505.7M-3.9%-$510.9M-5.6%-$493.5M-2.7%-$489.6M-2.7%

Not reported in any period shown, so not listed: Short-Term Investments, Inventory, Accounts Receivable, Long-Term Investments, Long-Term Debt.

PSTV Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

PSTV quarterly cash flow statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Cash Flow-$7.1M-23.0%-$6.2M-1.1%-$6.3M-416.7%-$2.5M+30.8%-$5.8M-404.2%-$6.2M-36.8%-$1.2M+35.6%-$3.7M-53.4%
Depreciation & AmortizationN/A$96K-34.2%N/AN/AN/A$146K-5.8%N/AN/A
Stock-Based CompensationN/A$1.0M+590.5%N/AN/AN/A$148K+1.4%N/AN/A
Capital Expenditures$499K+7028.6%$818K+27166.7%$30K+172.7%$27K+92.9%$7K-91.4%$3K-92.5%$11K-73.8%$14K+40.0%
Free Cash Flow-$7.6M-31.5%-$7.1M-14.3%-$6.3M-414.5%-$2.6M+30.3%-$5.8M-371.6%-$6.2M-35.6%-$1.2M+36.5%-$3.7M-53.3%
Investing Cash Flow$5.4M+215.8%-$8.5M-339.8%-$1.1M-1782.8%$1.3M+14511.1%-$4.6M-21.8%$3.6M+1077.5%$64K+252.4%-$9K+10.0%
Financing Cash Flow$1.1M-60.3%$9.0M-27.2%$2.8M$12.3M$2.8M-59.8%$12.4M+1698.6%$0+100.0%$0-100.0%
Share BuybacksN/AN/AN/AN/AN/AN/A$0$0

Not reported in any period shown, so not listed: Dividends Paid.

PSTV Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

PSTV quarterly financial ratios
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Margin-2203.7%-692.5%-420.0%-320.8%-110.7%-333.9%-276.2%-260.9%
Net Margin-2191.2%-675.7%-417.9%-316.6%370.6%-1643.2%-276.4%-197.4%
Return on Equity-164.8%-334.6pp-58.1%-143.0%-87.5%169.8%N/AN/AN/A
Return on Assets-64.2%-114.0pp-34.9%+109.5pp-35.0%+23.8pp-23.7%+17.5pp49.8%+76.0pp-144.3%-86.3pp-58.8%-41.2%-16.9pp
Current Ratio1.37+0.1x2.27+1.2x1.23+0.9x1.29+0.8x1.26+0.8x1.03+0.6x0.34-0.6x0.44-0.7x
Debt-to-Equity1.57-0.8x0.673.092.692.41N/AN/AN/A
Asset Turnover0.03-0.1x0.050.0x0.08-0.1x0.07-0.1x0.130.0x0.09-0.2x0.210.21
FCF Margin-1856.7%-686.4%-459.9%-184.3%-417.6%-583.1%-86.5%-253.7%

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
PLUS THERAPEUTICS, Inc. PSTV FY2025 $5.2M -$22.4M N/A $26.6M 32/100
Radiopharm Theranostics Limited RADX FY2025 $3.6M -$38.3M N/A $16.5M 20/100
Verrica Pharmaceuticals Inc. VRCA FY2025 $35.6M -$17.9M -50.3% $70.6M 68/100
Barinthus Biotherapeutics plc American BRNS FY2025 $0 -$66.4M N/A $30.2M —
BIOATLA INC BCAB FY2025 N/A $59.6M N/A $2.9M —
RenovoRx, Inc. RNXT FY2025 $1.1M -$11.2M N/A $57.8M 49/100

Frequently Asked Questions

What is PLUS THERAPEUTICS, Inc.'s annual revenue?

PLUS THERAPEUTICS, Inc. (PSTV) reported $5.2M in total revenue for fiscal year 2025. This represents a -10.5% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is PLUS THERAPEUTICS, Inc.'s revenue growing?

PLUS THERAPEUTICS, Inc. (PSTV) revenue declined by 10.5% year-over-year, from $5.8M to $5.2M in fiscal year 2025.

Is PLUS THERAPEUTICS, Inc. profitable?

No, PLUS THERAPEUTICS, Inc. (PSTV) reported a net income of -$22.4M in fiscal year 2025.

PLUS THERAPEUTICS, Inc. (PSTV) reported diluted earnings per share of -$0.29 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

PLUS THERAPEUTICS, Inc. (PSTV) had EBITDA of -$14.9M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

PLUS THERAPEUTICS, Inc. (PSTV) has a return on equity of -560.2% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

PLUS THERAPEUTICS, Inc. (PSTV) recorded an outflow of $20.8M in free cash flow during fiscal year 2025. This represents a -94.8% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

PLUS THERAPEUTICS, Inc. (PSTV) recorded an outflow of $20.8M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

PLUS THERAPEUTICS, Inc. (PSTV) had $16.3M in total assets as of fiscal year 2025, including both current and long-term assets.

PLUS THERAPEUTICS, Inc. (PSTV) invested $67K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

PLUS THERAPEUTICS, Inc. (PSTV) invested $8.4M in research and development during fiscal year 2025.

PLUS THERAPEUTICS, Inc. (PSTV) had 6M shares outstanding as of fiscal year 2025.

PLUS THERAPEUTICS, Inc. (PSTV) had a current ratio of 1.23 as of fiscal year 2025, which is considered adequate.

PLUS THERAPEUTICS, Inc. (PSTV) had a debt-to-equity ratio of 3.09 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

PLUS THERAPEUTICS, Inc. (PSTV) had a return on assets of -137.1% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

PLUS THERAPEUTICS, Inc. (PSTV) has an Altman Z-Score of -45.51, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

PLUS THERAPEUTICS, Inc. (PSTV) has a Piotroski F-Score of 4 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

PLUS THERAPEUTICS, Inc. (PSTV) reported a net loss of $22.4M while operations used $20.8M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

PLUS THERAPEUTICS, Inc. (PSTV) reported an operating loss of $15.3M against $548K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

PLUS THERAPEUTICS, Inc. (PSTV) scores 32 out of 100 on our Financial Health Score, indicating weak standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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