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Top Healthcare Stocks by Free Cash Flow

Top healthcare companies ranked by free cash flow, latest annual filings.

What Free Cash Flow Means for Healthcare Companies

Free cash flow in healthcare tends to be lumpier than in most sectors because the business model swings between long pre-approval cash burns and multi-year harvesting periods once a drug or device reaches market. Large pharma and device makers with broad portfolios can produce steady cash across cycles, while single-asset biotechs often report negative free cash flow for extended periods as trials, regulatory work, and launch spending precede any revenue at all.

Why It Matters in Healthcare

For established healthcare firms, consistent free cash flow tends to signal durable payer relationships and diversified pipelines, and it is what funds research spending, acquisitions, and shareholder returns. In biotech, free cash flow is often a poor snapshot of value because cash burn is expected until approval; runway and trial timelines matter more than current cash generation. Patent cliffs and pricing pressure can also flip steady cash generators into declining ones over a few years.

What to Read Alongside

Pair free cash flow with Net Income to check accounting quality, Share Buybacks to see capital return behavior, and Revenue for how sales are converting into cash across the portfolio.

Data as of FY 2025 100 companies Rhea AI
# Symbol Company Sector
1 JNJ Johnson & Johnson Healthcare $19.70B $657.68B
2 ABBV AbbVie Inc. Healthcare $17.82B $521.11B
3 NVS Novartis AG Healthcare $17.60B $303.67B
4 UNH UnitedHealth Group Incorporated Healthcare $16.07B $365.29B
5 BMY Bristol-Myers Squibb Company Healthcare $12.85B $127.71B
6 MRK Merck & Co., Inc. Healthcare $12.36B $368.89B
7 AZN AstraZeneca PLC Healthcare $11.77B $289.48B
8 GILD Gilead Sciences, Inc. Healthcare $9.46B $211.70B
9 NVO Novo Nordisk A/S Healthcare $9.26B $176.43B
10 PFE Pfizer Inc. Healthcare $9.07B $173.95B
11 GSK GSK plc Healthcare $8.60B $99.19B
12 AMGN Amgen Inc. Healthcare $8.10B $251.94B
13 CVS CVS Health Corporation Healthcare $7.81B $115.43B
14 HCA HCA Healthcare, Inc. Healthcare $7.69B $98.85B
15 ABT Abbott Laboratories Healthcare $7.39B $183.77B
16 TMO Thermo Fisher Scientific Inc. Healthcare $6.29B $257.71B
17 MCK McKesson Corporation Healthcare $5.72B $115.96B
18 TAK Takeda Pharmaceutical Company Limited Healthcare $5.71B $66.81B
19 MDT Medtronic plc Healthcare $5.43B $123.49B
20 DHR Danaher Corporation Healthcare $5.26B $163.25B
21 CAH Cardinal Health, Inc. Healthcare $4.53B $58.00B
22 CNC Centene Corporation Healthcare $4.32B $33.89B
23 SYK Stryker Corporation Healthcare $4.28B $111.95B
24 REGN Regeneron Pharmaceuticals, Inc. Healthcare $4.08B $95.99B
25 BSX Boston Scientific Corporation Healthcare $3.66B $60.84B
26 COR Cencora, Inc. Healthcare $3.21B $63.13B
27 VRTX Vertex Pharmaceuticals Incorporated Healthcare $3.19B $141.65B
28 ELV Elevance Health, Inc. Healthcare $3.17B $91.10B
29 HLN Haleon plc Healthcare $3.11B $38.08B
30 BDX Becton, Dickinson and Company Healthcare $2.67B $53.90B
31 THC Tenet Healthcare Corporation Healthcare $2.53B $21.75B
32 ISRG Intuitive Surgical, Inc. Healthcare $2.49B $152.62B
33 ZTS Zoetis Inc. Healthcare $2.28B $32.94B
34 IQV IQVIA Holdings Inc. Healthcare $2.05B $44.06B
35 BIIB Biogen Inc. Healthcare $2.05B $37.49B
36 VTRS Viatris Inc. Healthcare $1.94B $21.86B
37 ALC Alcon Inc. Healthcare $1.73B $34.54B
38 RMD ResMed Inc. Healthcare $1.65B $32.34B
39 GEHC GE HealthCare Technologies Inc. Healthcare $1.50B $34.62B
40 ZBH Zimmer Biomet Holdings, Inc. Healthcare $1.47B $18.03B
41 DGX Quest Diagnostics Incorporated Healthcare $1.36B $27.79B
42 EW Edwards Lifesciences Corporation Healthcare $1.33B $53.03B
43 DVA DaVita Inc. Healthcare $1.31B $11.79B
44 JAZZ Jazz Pharmaceuticals plc Healthcare $1.30B $14.02B
45 MDLN Medline Inc. Healthcare $1.30B $42.23B
46 LH Labcorp Holdings Inc. Healthcare $1.21B $29.34B
47 A Agilent Technologies, Inc. Healthcare $1.15B $49.30B
48 GMAB Genmab A/S Healthcare $1.15B $35.09B
49 TEVA Teva Pharmaceutical Industries Limited Healthcare $1.15B $49.09B
50 DXCM DexCom, Inc. Healthcare $1.08B $30.69B
51 OSCR Oscar Health, Inc. Healthcare $1.06B $9.37B
52 IDXX IDEXX Laboratories, Inc. Healthcare $1.06B $43.42B
53 UTHR United Therapeutics Corporation Healthcare $1.04B $25.68B
54 BHC Bausch Health Companies Inc. Healthcare $1.00B $3.07B
55 STE STERIS plc Healthcare $972.40M $22.14B
56 ONC BeOne Medicines AG Healthcare $941.74M $41.89B
57 ILMN Illumina, Inc. Healthcare $931.00M $35.63B
58 EXEL Exelixis, Inc. Healthcare $875.84M $16.93B
59 ICLR ICON Public Limited Company Healthcare $861.99M $15.83B
60 UHS Universal Health Services, Inc. Healthcare $849.25M $10.38B
61 MTD Mettler-Toledo International Inc. Healthcare $848.65M $33.56B
62 NBIX Neurocrine Biosciences, Inc. Healthcare $748.70M $14.85B
63 BMRN BioMarin Pharmaceutical Inc. Healthcare $724.96M $11.33B
64 PTCT PTC Therapeutics, Inc. Healthcare $702.34M $5.01B
65 GRFS Grifols, S.A. Healthcare $693.13M $5.51B
66 MEDP Medpace Holdings, Inc. Healthcare $681.87M $18.24B
67 ARGX argenx SE Healthcare $679.03M $56.15B
68 HALO Halozyme Therapeutics, Inc. Healthcare $644.59M $14.86B
69 GMED Globus Medical, Inc. Healthcare $588.77M $10.48B
70 HSIC Henry Schein, Inc. Healthcare $573.00M $9.46B
71 WAT Waters Corporation Healthcare $539.81M $45.46B
72 OGN Organon & Co. Healthcare $538.00M $3.63B
73 CRL Charles River Laboratories International, Inc. Healthcare $518.49M $17.16B
74 RVTY Revvity, Inc. Healthcare $509.41M $17.52B
75 AVTR Avantor, Inc. Healthcare $495.00M $10.88B
76 ALGN Align Technology, Inc. Healthcare $490.78M $10.65B
77 ALKS Alkermes plc Healthcare $480.33M $7.61B
78 WST West Pharmaceutical Services, Inc. Healthcare $468.90M $28.74B
79 ALNY Alnylam Pharmaceuticals, Inc. Healthcare $465.38M $22.10B
80 HQY HealthEquity, Inc. Healthcare $455.13M $8.48B
81 QGEN Qiagen N.V. Healthcare $453.28M $10.37B
82 EHC Encompass Health Corporation Healthcare $439.20M $13.36B
83 COO The Cooper Companies, Inc. Healthcare $433.70M $11.32B
84 BTSG BrightSpring Health Services, Inc. Healthcare $394.69M $13.31B
85 PODD Insulet Corporation Healthcare $377.70M $10.38B
86 HUM Humana Inc. Healthcare $375.00M $49.77B
87 BIO Bio-Rad Laboratories, Inc. Healthcare $374.60M $9.95B
88 RDY Dr. Reddy's Laboratories Limited Healthcare $358.00M $11.80B
89 LNTH Lantheus Holdings, Inc. Healthcare $354.05M $6.56B
90 HRMY Harmony Biosciences Holdings, Inc. Healthcare $347.89M $2.26B
91 BCRX BioCryst Pharmaceuticals, Inc. Healthcare $344.90M $2.16B
92 BAX Baxter International Inc. Healthcare $332.00M $11.90B
93 BNTX BioNTech SE Healthcare $329.66M $22.15B
94 COLL Collegium Pharmaceutical, Inc. Healthcare $327.58M $774.82M
95 DOCS Doximity, Inc. Healthcare $326.46M $5.84B
96 CHE Chemed Corporation Healthcare $325.48M $6.93B
97 ATR AptarGroup, Inc. Healthcare $299.58M $8.70B
98 TDOC Teladoc Health, Inc. Healthcare $285.46M $1.55B
99 ELAN Elanco Animal Health Incorporated Healthcare $284.00M $11.52B
100 WAY Waystar Holding Corp. Healthcare $283.19M $5.37B

How this ranking is built

Companies are ranked by free cash flow as reported in their most recent annual filing with the SEC. Figures shown are in US dollars (or percent, as noted), rounded to two decimals.

  • Source: annual 10-K / 20-F filings from companies trading on US exchanges (NYSE, Nasdaq, AMEX).
  • Fiscal year: whichever annual period the company has most recently filed. Fiscal years don't always align with the calendar year, so the "as of FY" stamp above reflects the most common year across the table.
  • Filtered out: warrants, preferred shares, and duplicate listings that share a parent company's financials.
  • Size floor: A company qualifies at $500 million in market cap or above. Below that, one mis-stated figure outranks the companies the list is about.
  • Currency check: A company whose annual revenue runs above 15 times its market cap is left out, because at that gap the two figures are not in the same currency.
  • Currency check: A company whose balance sheet runs above 150 times its market cap is left out for the same reason.
  • Market cap: stated at each company's latest close, which is newer than the annual figure ranked here.
  • Update cadence: refreshed as companies file new annual reports (typically within 60–90 days of fiscal year end).

Not financial advice. This is a research tool, not a recommendation.

Frequently asked questions

Why is free cash flow often lumpy across healthcare companies?

Drug and device development requires years of research, trials, and regulatory work before any revenue arrives, and those costs flow through cash well before sales. Once a product is approved, cash conversion can accelerate dramatically as manufacturing scales and marketing spend levels off. Patent expirations, generic entry, and payer pricing resets then produce declines that are hard to offset in a single period. The result is that free cash flow for a given firm often looks quite different across a five to ten year window.

Why do biotechs often have negative free cash flow?

Clinical-stage biotechs typically spend heavily on trials, manufacturing preparation, and regulatory submissions for years before generating any product revenue. Cash is raised through equity issuance, partnerships, or debt to fund that runway. Negative free cash flow in this context is expected rather than a warning sign by itself, and investors typically focus on cash balance versus projected burn, trial milestones, and the scientific case for the lead asset rather than on free cash flow as a profitability measure.