Caribou Biosciences, Inc. Financials
This page shows Caribou Biosciences, Inc. (CRBU) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 7 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).
Financial Health Signals
Based on FY2025 annual data. Scores normalized against common benchmarks. How we calculate these scores
Caribou Biosciences, Inc. has an operating margin of -1329.4%, meaning the company retains $-1329 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses. This is up from -1667.2% the prior year.
Caribou Biosciences, Inc.'s revenue grew 11.7% year-over-year to $11.2M, a solid pace of expansion. This earns a growth score of 53/100.
Caribou Biosciences, Inc. carries a low D/E ratio of 0.44, meaning only $0.44 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 93/100, indicating a strong balance sheet with room for future borrowing.
With a current ratio of 5.71, Caribou Biosciences, Inc. holds $5.71 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 100/100.
While Caribou Biosciences, Inc. generated -$111.0M in operating cash flow, capex of $1.4M consumed most of it, leaving -$112.4M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.
Caribou Biosciences, Inc. generates a -121.2% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100. This is down from -59.0% the prior year.
Caribou Biosciences, Inc. passes 2 of 9 financial strength tests. 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), both operating efficiency signals pass.
For every $1 of reported earnings, Caribou Biosciences, Inc. generates $0.75 in operating cash flow (-$111.0M OCF vs -$148.1M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.
Key Financial Metrics
Earnings & Revenue
Caribou Biosciences, Inc. generated $11.2M in revenue in fiscal year 2025. This represents an increase of 11.7% from the prior year.
Caribou Biosciences, Inc.'s EBITDA was -$144.7M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 11.1% from the prior year.
Caribou Biosciences, Inc. reported -$148.1M in net income in fiscal year 2025. This represents an increase of 0.7% from the prior year.
Caribou Biosciences, Inc. earned $-1.59 per diluted share (EPS) in fiscal year 2025. This represents an increase of 3.6% from the prior year.
Cash & Balance Sheet
Caribou Biosciences, Inc. generated -$112.4M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 21.5% from the prior year.
Caribou Biosciences, Inc. held $12.4M in cash against $0 in long-term debt as of fiscal year 2025.
Caribou Biosciences, Inc. had 95M shares outstanding in fiscal year 2025. This represents an increase of 3.0% from the prior year.
Margins & Returns
Caribou Biosciences, Inc.'s operating margin was -1329.4% in fiscal year 2025, reflecting core business profitability. This is up 337.8 percentage points from the prior year.
Caribou Biosciences, Inc.'s net profit margin was -1327.4% in fiscal year 2025, showing the share of revenue converted to profit. This is up 164.6 percentage points from the prior year.
Caribou Biosciences, Inc.'s ROE was -121.2% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is down 62.3 percentage points from the prior year.
Capital Allocation
Caribou Biosciences, Inc. invested $109.4M in research and development in fiscal year 2025. This represents a decrease of 15.9% from the prior year.
Caribou Biosciences, Inc. invested $1.4M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 72.2% from the prior year.
CRBU Income Statement
| Metric | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $3.9M+79.3% | $2.2M-17.6% | $2.7M+13.3% | $2.4M+13.3% | $2.1M+2.6% | $2.0M-41.6% | $3.5M+42.6% | $2.4M |
| Cost of Revenue | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Gross Profit | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| R&D Expenses | $23.8M+6.3% | $22.4M-19.1% | $27.7M-22.1% | $35.5M+16.6% | $30.5M+0.1% | $30.4M-14.3% | $35.5M+5.0% | $33.8M |
| SG&A Expenses | $8.6M-6.7% | $9.2M-11.6% | $10.4M+6.9% | $9.7M-7.2% | $10.5M+6.6% | $9.8M-14.3% | $11.5M-21.6% | $14.6M |
| Operating Income | -$28.5M+3.2% | -$29.4M+38.2% | -$47.6M-10.9% | -$42.9M-10.4% | -$38.9M-1.7% | -$38.2M+12.1% | -$43.5M+5.4% | -$46.0M |
| Interest Expense | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Income Tax | N/A | $0 | N/A | $0+100.0% | -$9K | $0 | $0 | $0 |
| Net Income | -$26.5M+3.8% | -$27.5M+49.1% | -$54.1M-35.3% | -$40.0M-12.7% | -$35.5M-2.3% | -$34.7M+8.0% | -$37.7M+8.6% | -$41.2M |
| EPS (Diluted) | N/A | $-0.30+48.3% | $-0.58-34.9% | $-0.43 | N/A | $-0.38+9.5% | $-0.42+8.7% | $-0.46 |
CRBU Balance Sheet
| Metric | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 |
|---|---|---|---|---|---|---|---|---|
| Total Assets | $175.4M-10.1% | $195.0M-11.7% | $220.9M-19.3% | $273.7M-12.7% | $313.3M-9.0% | $344.3M-7.7% | $372.9M-8.3% | $406.8M |
| Current Assets | $145.2M-6.6% | $155.5M-19.2% | $192.5M-11.4% | $217.3M-0.9% | $219.4M-7.6% | $237.4M-12.4% | $270.9M-11.0% | $304.5M |
| Cash & Equivalents | $12.4M+10.9% | $11.1M-55.8% | $25.2M-14.3% | $29.4M+80.5% | $16.3M-49.0% | $32.0M-15.6% | $37.9M-23.3% | $49.4M |
| Inventory | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Accounts Receivable | $69K-71.5% | $242K+240.8% | $71K-19.3% | $88K-66.8% | $265K+44.0% | $184K-14.4% | $215K-76.6% | $917K |
| Goodwill | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Total Liabilities | $53.2M+0.1% | $53.1M-3.0% | $54.8M-2.9% | $56.4M-6.5% | $60.4M-4.4% | $63.1M+1.1% | $62.5M-1.7% | $63.5M |
| Current Liabilities | $25.4M-9.4% | $28.1M-2.9% | $28.9M+1.4% | $28.5M-7.0% | $30.7M-4.7% | $32.2M+3.9% | $30.9M+6.6% | $29.0M |
| Long-Term Debt | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Total Equity | $122.2M-13.9% | $141.8M-14.6% | $166.1M-23.5% | $217.2M-14.1% | $253.0M-10.0% | $281.2M-9.4% | $310.5M-9.6% | $343.3M |
| Retained Earnings | -$596.5M-4.6% | -$570.0M-5.1% | -$542.5M-11.1% | -$488.4M-8.9% | -$448.4M-8.6% | -$412.9M-9.2% | -$378.2M-11.1% | -$340.5M |
CRBU Cash Flow Statement
| Metric | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 |
|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | -$20.8M+17.3% | -$25.2M+10.9% | -$28.3M+23.1% | -$36.7M-3.5% | -$35.5M-8.6% | -$32.7M+0.6% | -$32.9M+11.7% | -$37.2M |
| Capital Expenditures | -$216K-287.8% | $115K-72.5% | $418K-59.9% | $1.0M+101.2% | $518K-23.0% | $673K-70.0% | $2.2M+54.8% | $1.4M |
| Free Cash Flow | -$21.0M+16.8% | -$25.3M+11.8% | -$28.7M+24.1% | -$37.8M-4.9% | -$36.0M-8.0% | -$33.3M+5.1% | -$35.1M+9.2% | -$38.7M |
| Investing Cash Flow | $18.0M+65.6% | $10.9M-54.9% | $24.0M-51.3% | $49.4M+210.0% | $15.9M-39.9% | $26.5M+25.1% | $21.2M-7.6% | $23.0M |
| Financing Cash Flow | $4.1M+1369.3% | $277K+4516.7% | $6K-98.7% | $468K-87.9% | $3.9M+1483.2% | $244K+84.8% | $132K-98.9% | $12.5M |
| Dividends Paid | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Share Buybacks | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
CRBU Financial Ratios
| Metric | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 |
|---|---|---|---|---|---|---|---|---|
| Gross Margin | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Operating Margin | -722.0%+615.6pp | -1337.6%+446.4pp | -1784.0%+39.8pp | -1823.8%+47.9pp | -1871.7%+17.5pp | -1889.2%-633.4pp | -1255.8%+638.1pp | -1893.9% |
| Net Margin | -672.1%+581.2pp | -1253.3%+775.1pp | -2028.4%-328.8pp | -1699.6%+9.1pp | -1708.7%+4.9pp | -1713.6%-625.4pp | -1088.3%+609.3pp | -1697.6% |
| Return on Equity | -21.7%-2.3pp | -19.4%+13.1pp | -32.6%-14.1pp | -18.4%-4.4pp | -14.0%-1.7pp | -12.3%-0.2pp | -12.1%-0.1pp | -12.0% |
| Return on Assets | -15.1%-1.0pp | -14.1%+10.4pp | -24.5%-9.9pp | -14.6%-3.3pp | -11.3%-1.3pp | -10.1%+0.0pp | -10.1%+0.0pp | -10.1% |
| Current Ratio | 5.71+0.2 | 5.54-1.1 | 6.66-1.0 | 7.63+0.5 | 7.16-0.2 | 7.38-1.4 | 8.75-1.7 | 10.49 |
| Debt-to-Equity | 0.44+0.1 | 0.37+0.0 | 0.33+0.1 | 0.26+0.0 | 0.24+0.0 | 0.22+0.0 | 0.20+0.0 | 0.19 |
| FCF Margin | -533.9%+617.2pp | -1151.0%-75.8pp | -1075.2%+529.8pp | -1605.1%+127.6pp | -1732.7%-85.7pp | -1646.9%-633.5pp | -1013.5%+577.8pp | -1591.2% |
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Frequently Asked Questions
What is Caribou Biosciences, Inc.'s annual revenue?
Caribou Biosciences, Inc. (CRBU) reported $11.2M in total revenue for fiscal year 2025. This represents a 11.7% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.
How fast is Caribou Biosciences, Inc.'s revenue growing?
Caribou Biosciences, Inc. (CRBU) revenue grew by 11.7% year-over-year, from $10.0M to $11.2M in fiscal year 2025.
Is Caribou Biosciences, Inc. profitable?
No, Caribou Biosciences, Inc. (CRBU) reported a net income of -$148.1M in fiscal year 2025, with a net profit margin of -1327.4%.
What is Caribou Biosciences, Inc.'s EBITDA?
Caribou Biosciences, Inc. (CRBU) had EBITDA of -$144.7M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.
What is Caribou Biosciences, Inc.'s operating margin?
Caribou Biosciences, Inc. (CRBU) had an operating margin of -1329.4% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.
What is Caribou Biosciences, Inc.'s net profit margin?
Caribou Biosciences, Inc. (CRBU) had a net profit margin of -1327.4% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.
What is Caribou Biosciences, Inc.'s return on equity (ROE)?
Caribou Biosciences, Inc. (CRBU) has a return on equity of -121.2% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.
What is Caribou Biosciences, Inc.'s free cash flow?
Caribou Biosciences, Inc. (CRBU) generated -$112.4M in free cash flow during fiscal year 2025. This represents a 21.5% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.
What is Caribou Biosciences, Inc.'s operating cash flow?
Caribou Biosciences, Inc. (CRBU) generated -$111.0M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.
What are Caribou Biosciences, Inc.'s total assets?
Caribou Biosciences, Inc. (CRBU) had $175.4M in total assets as of fiscal year 2025, including both current and long-term assets.
What are Caribou Biosciences, Inc.'s capital expenditures?
Caribou Biosciences, Inc. (CRBU) invested $1.4M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.
How much does Caribou Biosciences, Inc. spend on research and development?
Caribou Biosciences, Inc. (CRBU) invested $109.4M in research and development during fiscal year 2025.
What is Caribou Biosciences, Inc.'s current ratio?
Caribou Biosciences, Inc. (CRBU) had a current ratio of 5.71 as of fiscal year 2025, which is generally considered healthy.
What is Caribou Biosciences, Inc.'s debt-to-equity ratio?
Caribou Biosciences, Inc. (CRBU) had a debt-to-equity ratio of 0.44 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.
What is Caribou Biosciences, Inc.'s return on assets (ROA)?
Caribou Biosciences, Inc. (CRBU) had a return on assets of -84.5% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.
What is Caribou Biosciences, Inc.'s cash runway?
Based on fiscal year 2025 data, Caribou Biosciences, Inc. (CRBU) had $12.4M in cash against an annual operating cash burn of $111.0M. This gives an estimated cash runway of approximately 1 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.
What is Caribou Biosciences, Inc.'s Piotroski F-Score?
Caribou Biosciences, Inc. (CRBU) has a Piotroski F-Score of 2 out of 9, indicating weak financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.
Are Caribou Biosciences, Inc.'s earnings high quality?
Caribou Biosciences, Inc. (CRBU) has an earnings quality ratio of 0.75x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.
How financially healthy is Caribou Biosciences, Inc.?
Caribou Biosciences, Inc. (CRBU) scores 41 out of 100 on our Financial Profile, indicating moderate overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.