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Caribou Biosciences, Inc. Financials

CRBU
Source SEC Filings (10-K/10-Q) Updated Sep 30, 2025 Currency USD FYE December

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 40 / 100
Financial Profile 40/100

Based on FY2024 annual data. Scores normalized against common benchmarks. How we calculate these scores

Profitability
0

Caribou Biosciences, Inc. has an operating margin of -1667.2%, meaning the company retains $-1667 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses. This is down from -336.6% the prior year.

Growth
0

Caribou Biosciences, Inc.'s revenue declined 71% year-over-year, from $34.5M to $10.0M. This contraction results in a growth score of 0/100.

Leverage
100

Caribou Biosciences, Inc. carries a low D/E ratio of 0.24, meaning only $0.24 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 100/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
100

With a current ratio of 7.16, Caribou Biosciences, Inc. holds $7.16 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 100/100.

Cash Flow
0

While Caribou Biosciences, Inc. generated -$138.2M in operating cash flow, capex of $4.9M consumed most of it, leaving -$143.1M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.

Piotroski F-Score Weak
1/9

Caribou Biosciences, Inc. passes 1 of 9 financial strength tests. 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), neither operating efficiency signal passes.

Earnings Quality Low Quality
0.93x

For every $1 of reported earnings, Caribou Biosciences, Inc. generates $0.93 in operating cash flow (-$138.2M OCF vs -$149.1M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

This page shows Caribou Biosciences, Inc. (CRBU) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

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Key Financial Metrics

Revenue
$10.0M
YoY-71.0%
5Y CAGR+11.5%

Caribou Biosciences, Inc. generated $10.0M in revenue in fiscal year 2024. This represents a decrease of 71.0% from the prior year.

EBITDA
-$162.7M
YoY-44.6%

Caribou Biosciences, Inc.'s EBITDA was -$162.7M in fiscal year 2024, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 44.6% from the prior year.

Free Cash Flow
-$143.1M
YoY-36.4%

Caribou Biosciences, Inc. generated -$143.1M in free cash flow in fiscal year 2024, representing cash available after capex. This represents a decrease of 36.4% from the prior year.

Net Income
-$149.1M
YoY-46.1%

Caribou Biosciences, Inc. reported -$149.1M in net income in fiscal year 2024. This represents a decrease of 46.1% from the prior year.

EPS (Diluted)
$-1.65
YoY-19.6%

Caribou Biosciences, Inc. earned $-1.65 per diluted share (EPS) in fiscal year 2024. This represents a decrease of 19.6% from the prior year.

Cash & Debt
$16.3M
YoY-68.2%
5Y CAGR-16.9%

Caribou Biosciences, Inc. held $16.3M in cash against $0 in long-term debt as of fiscal year 2024.

Dividends Per Share
N/A
Shares Outstanding
92M
YoY+4.4%

Caribou Biosciences, Inc. had 92M shares outstanding in fiscal year 2024. This represents an increase of 4.4% from the prior year.

Gross Margin
N/A
Operating Margin
-1667.2%
YoY-1330.5pp
5Y CAGR-1074.5pp

Caribou Biosciences, Inc.'s operating margin was -1667.2% in fiscal year 2024, reflecting core business profitability. This is down 1330.5 percentage points from the prior year.

Net Margin
-1491.9%
YoY-1195.9pp
5Y CAGR-1087.1pp

Caribou Biosciences, Inc.'s net profit margin was -1491.9% in fiscal year 2024, showing the share of revenue converted to profit. This is down 1195.9 percentage points from the prior year.

Return on Equity
N/A
R&D Spending
$130.2M
YoY+16.1%
5Y CAGR+40.7%

Caribou Biosciences, Inc. invested $130.2M in research and development in fiscal year 2024. This represents an increase of 16.1% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$4.9M
YoY-58.0%
5Y CAGR+40.7%

Caribou Biosciences, Inc. invested $4.9M in capex in fiscal year 2024, funding long-term assets and infrastructure. This represents a decrease of 58.0% from the prior year.

CRBU Income Statement

Metric Q3'25 Q2'25 Q1'25 Q3'24 Q2'24 Q1'24 Q4'23 Q3'23
Revenue $2.2M-17.6% $2.7M+13.3% $2.4M+13.3% $2.1M-40.0% $3.5M+42.6% $2.4M-31.7% $3.6M-85.0% $23.7M
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A N/A
R&D Expenses $22.4M-19.1% $27.7M-22.1% $35.5M+16.6% $30.5M-14.1% $35.5M+5.0% $33.8M+8.0% $31.3M+9.4% $28.6M
SG&A Expenses $9.2M-11.6% $10.4M+6.9% $9.7M-7.2% $10.5M-8.7% $11.5M-21.6% $14.6M+50.6% $9.7M+0.1% $9.7M
Operating Income -$29.4M+38.2% -$47.6M-10.9% -$42.9M-10.4% -$38.9M+10.6% -$43.5M+5.4% -$46.0M-22.9% -$37.4M-155.9% -$14.6M
Interest Expense N/A N/A N/A N/A N/A N/A N/A N/A
Income Tax $0 N/A $0+100.0% -$9K $0 $0-100.0% $193K $0
Net Income -$27.5M+49.1% -$54.1M-35.3% -$40.0M-12.7% -$35.5M+5.9% -$37.7M+8.6% -$41.2M-19.5% -$34.5M-245.0% -$10.0M
EPS (Diluted) $-0.30+48.3% $-0.58-34.9% $-0.43-10.3% $-0.39+7.1% $-0.42+8.7% $-0.46-43.8% $-0.32-166.7% $-0.12

CRBU Balance Sheet

Metric Q3'25 Q2'25 Q1'25 Q3'24 Q2'24 Q1'24 Q4'23 Q3'23
Total Assets $195.0M-11.7% $220.9M-19.3% $273.7M-12.7% $313.3M-16.0% $372.9M-8.3% $406.8M-5.9% $432.2M-5.5% $457.5M
Current Assets $155.5M-19.2% $192.5M-11.4% $217.3M-0.9% $219.4M-19.0% $270.9M-11.0% $304.5M-10.1% $338.8M-3.4% $350.7M
Cash & Equivalents $11.1M-55.8% $25.2M-14.3% $29.4M+80.5% $16.3M-57.0% $37.9M-23.3% $49.4M-3.4% $51.2M-50.8% $104.1M
Inventory N/A N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable $242K+240.8% $71K-19.3% $88K-66.8% $265K+23.3% $215K-76.6% $917K+519.6% $148K-86.9% $1.1M
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $53.1M-3.0% $54.8M-2.9% $56.4M-6.5% $60.4M-3.4% $62.5M-1.7% $63.5M-0.4% $63.8M+7.7% $59.3M
Current Liabilities $28.1M-2.9% $28.9M+1.4% $28.5M-7.0% $30.7M-0.9% $30.9M+6.6% $29.0M+2.5% $28.3M+15.2% $24.6M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $141.8M-14.6% $166.1M-23.5% $217.2M-14.1% $253.0M-18.5% $310.5M-9.6% $343.3M-6.8% $368.4M-7.5% $398.3M
Retained Earnings -$570.0M-5.1% -$542.5M-11.1% -$488.4M-8.9% -$448.4M-18.6% -$378.2M-11.1% -$340.5M-13.8% -$299.3M-13.0% -$264.8M

CRBU Cash Flow Statement

Metric Q3'25 Q2'25 Q1'25 Q3'24 Q2'24 Q1'24 Q4'23 Q3'23
Operating Cash Flow -$25.2M+10.9% -$28.3M+23.1% -$36.7M-3.5% -$35.5M-7.9% -$32.9M+11.7% -$37.2M-74.0% -$21.4M+25.7% -$28.8M
Capital Expenditures $115K-72.5% $418K-59.9% $1.0M+101.2% $518K-76.9% $2.2M+54.8% $1.4M-36.4% $2.3M-52.1% $4.8M
Free Cash Flow -$25.3M+11.8% -$28.7M+24.1% -$37.8M-4.9% -$36.0M-2.5% -$35.1M+9.2% -$38.7M-63.4% -$23.7M+29.5% -$33.5M
Investing Cash Flow $10.9M-54.9% $24.0M-51.3% $49.4M+210.0% $15.9M-24.9% $21.2M-7.6% $23.0M+172.9% -$31.5M+54.0% -$68.5M
Financing Cash Flow $277K+4516.7% $6K-98.7% $468K-87.9% $3.9M+2826.5% $132K-98.9% $12.5M+29134.9% -$43K-100.0% $135.1M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

CRBU Financial Ratios

Metric Q3'25 Q2'25 Q1'25 Q3'24 Q2'24 Q1'24 Q4'23 Q3'23
Gross Margin N/A N/A N/A N/A N/A N/A N/A N/A
Operating Margin -1337.6%+446.4pp -1784.0%+39.8pp -1823.8%+47.9pp -1871.7%-615.9pp -1255.8%+638.1pp -1893.9%-841.5pp -1052.3%-990.5pp -61.8%
Net Margin -1253.3%+775.1pp -2028.4%-328.8pp -1699.6%+9.1pp -1708.7%-620.5pp -1088.3%+609.3pp -1697.6%-727.8pp -969.8%-927.5pp -42.3%
Return on Equity N/A N/A N/A N/A N/A N/A N/A N/A
Return on Assets -14.1%+10.4pp -24.5%-9.9pp -14.6%-3.3pp -11.3%-1.2pp -10.1%+0.0pp -10.1%-2.2pp -8.0%-5.8pp -2.2%
Current Ratio 5.54-1.1 6.66-1.0 7.63+0.5 7.16-1.6 8.75-1.7 10.49-1.5 11.97-2.3 14.27
Debt-to-Equity 0.37+0.0 0.33+0.1 0.26+0.0 0.24+0.0 0.20+0.0 0.19+0.0 0.17+0.0 0.15
FCF Margin -1151.0%-75.8pp -1075.2%+529.8pp -1605.1%+127.6pp -1732.7%-719.2pp -1013.5%+577.8pp -1591.2%-926.4pp -664.9%-523.1pp -141.8%

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Frequently Asked Questions

What is Caribou Biosciences, Inc.'s annual revenue?

Caribou Biosciences, Inc. (CRBU) reported $10.0M in total revenue for fiscal year 2024. This represents a -71.0% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Caribou Biosciences, Inc.'s revenue growing?

Caribou Biosciences, Inc. (CRBU) revenue declined by 71% year-over-year, from $34.5M to $10.0M in fiscal year 2024.

Is Caribou Biosciences, Inc. profitable?

No, Caribou Biosciences, Inc. (CRBU) reported a net income of -$149.1M in fiscal year 2024, with a net profit margin of -1491.9%.

What is Caribou Biosciences, Inc.'s earnings per share (EPS)?

Caribou Biosciences, Inc. (CRBU) reported diluted earnings per share of $-1.65 for fiscal year 2024. This represents a -19.6% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

What is Caribou Biosciences, Inc.'s EBITDA?

Caribou Biosciences, Inc. (CRBU) had EBITDA of -$162.7M in fiscal year 2024, measuring earnings before interest, taxes, depreciation, and amortization.

What is Caribou Biosciences, Inc.'s operating margin?

Caribou Biosciences, Inc. (CRBU) had an operating margin of -1667.2% in fiscal year 2024, reflecting the profitability of core business operations before interest and taxes.

What is Caribou Biosciences, Inc.'s net profit margin?

Caribou Biosciences, Inc. (CRBU) had a net profit margin of -1491.9% in fiscal year 2024, representing the share of revenue converted into profit after all expenses.

What is Caribou Biosciences, Inc.'s free cash flow?

Caribou Biosciences, Inc. (CRBU) generated -$143.1M in free cash flow during fiscal year 2024. This represents a -36.4% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

What is Caribou Biosciences, Inc.'s operating cash flow?

Caribou Biosciences, Inc. (CRBU) generated -$138.2M in operating cash flow during fiscal year 2024, representing cash generated from core business activities.

What are Caribou Biosciences, Inc.'s total assets?

Caribou Biosciences, Inc. (CRBU) had $313.3M in total assets as of fiscal year 2024, including both current and long-term assets.

What are Caribou Biosciences, Inc.'s capital expenditures?

Caribou Biosciences, Inc. (CRBU) invested $4.9M in capital expenditures during fiscal year 2024, funding long-term assets and infrastructure.

How much does Caribou Biosciences, Inc. spend on research and development?

Caribou Biosciences, Inc. (CRBU) invested $130.2M in research and development during fiscal year 2024.

How many shares does Caribou Biosciences, Inc. have outstanding?

Caribou Biosciences, Inc. (CRBU) had 92M shares outstanding as of fiscal year 2024.

What is Caribou Biosciences, Inc.'s current ratio?

Caribou Biosciences, Inc. (CRBU) had a current ratio of 7.16 as of fiscal year 2024, which is generally considered healthy.

What is Caribou Biosciences, Inc.'s debt-to-equity ratio?

Caribou Biosciences, Inc. (CRBU) had a debt-to-equity ratio of 0.24 as of fiscal year 2024, measuring the company's financial leverage by comparing total debt to shareholder equity.

What is Caribou Biosciences, Inc.'s return on assets (ROA)?

Caribou Biosciences, Inc. (CRBU) had a return on assets of -47.6% for fiscal year 2024, measuring how efficiently the company uses its assets to generate profit.

What is Caribou Biosciences, Inc.'s cash runway?

Based on fiscal year 2024 data, Caribou Biosciences, Inc. (CRBU) had $16.3M in cash against an annual operating cash burn of $138.2M. This gives an estimated cash runway of approximately 1 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

What is Caribou Biosciences, Inc.'s Piotroski F-Score?

Caribou Biosciences, Inc. (CRBU) has a Piotroski F-Score of 1 out of 9, indicating weak financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Are Caribou Biosciences, Inc.'s earnings high quality?

Caribou Biosciences, Inc. (CRBU) has an earnings quality ratio of 0.93x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

How financially healthy is Caribou Biosciences, Inc.?

Caribou Biosciences, Inc. (CRBU) scores 40 out of 100 on our Financial Profile, indicating moderate overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.