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C4 Therapeutics, Inc. (CCCC) Financials

CCCC
Trailing 12 months to June 30, 2026
Revenue $35.0M +2.3% YoY
Net Income -$101.4M +9.1% YoY
EPS (Diluted) -$0.91 YoY not available
Free Cash Flow -$85.4M +2.5% YoY
Market Cap $388.8M as of Oct 10, 2026
Price / Sales 11.1x on $35.0M revenue, trailing 12 months to June 30, 2026
Price / Earnings n/m net loss, so no earnings multiple, trailing 12 months to June 30, 2026
Price / Book 1.6x on $247.3M equity, Q2 FY2026

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Oct 10, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q2 FY2026, filed Aug 11, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the CCCC SEC filings page.

C4 Therapeutics, Inc. (CCCC) reported $35.0M in revenue over the twelve months to Jun 30, 2026, up 2.3% from the prior twelve months. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 7 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI CCCC FY2025

C4 operates as a development-stage company, with research spending far above revenue and external financing funding ongoing cash needs.

In FY2025, revenue held near FY2024 at $35.9M, yet operating cash outflow widened to $98.7M. That divergence means the rebound from FY2023 did not translate into better cash conversion; the cost base remained geared toward development rather than near-term operating self-funding.

R&D was 2.9x FY2025 revenue, while the operating loss remained $115.2M, so reported commercial activity is still small relative to the resources committed to development work. This makes revenue scale a poor proxy for current operating capacity.

Financing cash flow of $126.4M more than offset operating cash outflow of $98.7M, making external financing—not operations—the main source of 2025 cash support. The reported liquidity comparison equaled 36.1 months of the latest annual operating outflow, a balance-sheet cushion measured against past spending rather than evidence of operating profitability.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 65 / 100
Financial Health Score 65/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of C4 Therapeutics, Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
60

C4 Therapeutics, Inc. held $297.1M in cash, cash equivalents and investments at the end of fiscal year 2025, and its operations used $98.7M of cash that year. Cash Runway ranks emerging companies on the size of that balance against the outflow behind it, and C4 Therapeutics, Inc. scores 60/100 among other emerging companies.

Dilution
36

C4 Therapeutics, Inc. had 98M shares outstanding at the end of fiscal year 2025, against 71M in fiscal year 2024. Dilution ranks emerging companies on how fast that count has grown over three years, where a slower rise is the better one, and C4 Therapeutics, Inc. scores 36/100 among other emerging companies.

R&D Intensity
90

C4 Therapeutics, Inc. spent $104.2M on research and development in fiscal year 2025, which was 69.0% of its operating costs that year. R&D Intensity ranks emerging companies on the share of operating costs that goes into research, and C4 Therapeutics, Inc. scores 90/100 among other emerging companies.

Revenue Progress
73

C4 Therapeutics, Inc. reported revenue of $35.9M in fiscal year 2025, against $35.6M in fiscal year 2024. Revenue Progress ranks emerging companies on the three-year path of that line, and C4 Therapeutics, Inc. scores 73/100 among other emerging companies.

Burn Trend
49

C4 Therapeutics, Inc.'s operations used $98.7M of cash in fiscal year 2025, against $65.2M used in fiscal year 2024. Burn Trend ranks emerging companies on which way that figure has moved over three years, and C4 Therapeutics, Inc. scores 49/100 among other emerging companies.

Balance Sheet
82

C4 Therapeutics, Inc.'s cash, cash equivalents and investments came to $297.1M at the end of fiscal year 2025, against $102.5M of total liabilities. Balance Sheet ranks emerging companies on that comparison, and C4 Therapeutics, Inc. scores 82/100 among other emerging companies.

Altman Z-Score Distress
-0.81

C4 Therapeutics, Inc. scores -0.81, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($388.8M) relative to total liabilities ($102.5M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
3/7

C4 Therapeutics, Inc. passes 3 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 2 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality No Cash Backing
N/A

C4 Therapeutics, Inc. reported a net loss of $105.0M while operations used $98.7M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$6.6M
YoY+2.8%
QoQ+7.9%

C4 Therapeutics, Inc. generated $6.6M in revenue in Q2 2026. This represents an increase of 2.8% from the same quarter a year earlier. Against the prior quarter it is up 7.9%.

EBITDA
-$26.1M
YoY+7.1%
QoQ+4.7%

C4 Therapeutics, Inc.'s EBITDA was -$26.1M in Q2 2026, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 7.1% from the same quarter a year earlier. Against the prior quarter it is up 4.7%.

Net Income
-$23.6M
YoY+9.2%
QoQ+5.9%

C4 Therapeutics, Inc. reported -$23.6M in net income in Q2 2026. This represents an increase of 9.2% from the same quarter a year earlier. Against the prior quarter it is up 5.9%.

EPS (Diluted)
-$0.18
QoQ+10.0%

C4 Therapeutics, Inc. earned -$0.18 per diluted share (EPS) in Q2 2026. Against the prior quarter it is up 10.0%.

Cash & Balance Sheet

Free Cash Flow
-$1.6M
YoY+86.8%
QoQ+94.6%

C4 Therapeutics, Inc. recorded an outflow of $1.6M in free cash flow in Q2 2026, representing a cash shortfall after capex. This represents an increase of 86.8% from the same quarter a year earlier. Against the prior quarter it is up 94.6%.

Cash & Debt
$78.6M
YoY+0.6%
QoQ+28.3%
5Y CAGR-22.5%

C4 Therapeutics, Inc. held $78.6M in cash as of Q2 2026; long-term debt is not reported for that period.

Shares Outstanding
123M
QoQ+11.3%
5Y CAGR+20.5%

C4 Therapeutics, Inc. had 123M shares outstanding in Q2 2026. Against the prior quarter it is up 11.3%.

Dividends Per Share

Not reported for Q2 2026.

Margins & Returns

Return on Equity
-9.6%
YoY+5.4pp
QoQ+1.2pp

C4 Therapeutics, Inc.'s ROE was -9.6% in Q2 2026, measuring profit generated per dollar of shareholder equity. This is up 5.4 percentage points from the same quarter a year earlier. Against the prior quarter it is up 1.2 percentage points.

Gross Margin

Not reported for Q2 2026.

Operating Margin

Not shown for Q2 2026: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for Q2 2026: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$24.5M
YoY-6.6%
QoQ-0.5%

C4 Therapeutics, Inc. invested $24.5M in research and development in Q2 2026. This represents a decrease of 6.6% from the same quarter a year earlier. Against the prior quarter it is down 0.5%.

Share Buybacks
$0
QoQ-100.0%

C4 Therapeutics, Inc. repurchased no shares in Q2 2026. Against the prior quarter it is down 100.0%.

Capital Expenditures
$37K
YoY-80.0%
QoQ-42.2%
5Y CAGR-45.2%

C4 Therapeutics, Inc. invested $37K in capex in Q2 2026, funding long-term assets and infrastructure. This represents a decrease of 80.0% from the same quarter a year earlier. Against the prior quarter it is down 42.2%.

CCCC Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CCCC quarterly income statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Revenue$6.6M+2.8%$6.2M-15.0%$11.0M+112.8%$11.2M-26.9%$6.5M-46.2%$7.2M+138.2%$5.2M+58.8%$15.4M+38.7%
R&D Expenses$24.5M-6.6%$24.6M-9.1%$25.0M-23.2%$26.0M-18.4%$26.2M+10.3%$27.1M+20.1%$32.5M+7.0%$31.8M+12.3%
SG&A Expenses$8.6M-2.0%$9.3M0.0%$9.2M-11.5%$8.9M-24.2%$8.8M-9.6%$9.3M-9.3%$10.4M+0.7%$11.8M+11.7%
Operating Income-$26.4M+7.3%-$27.8M+4.7%-$23.1M+38.6%-$34.4M-21.8%-$28.5M-32.9%-$29.2M+9.5%-$37.7M-0.8%-$28.2M-1.6%
EBITDA-$26.1M+7.1%-$27.4M+4.6%-$22.4M+39.3%-$34.0M-22.1%-$28.1M-32.8%-$28.7M+9.6%-$37.0M0.0%-$27.9M-1.9%
Income Tax$0$0$121K-7.6%$0$0$0$131K-52.7%$0-100.0%
Net Income-$23.6M+9.2%-$25.1M+4.5%-$20.5M+40.7%-$32.2M-30.4%-$26.0M-46.9%-$26.3M+7.2%-$34.6M+0.5%-$24.7M+8.8%
EPS (Basic)-$0.18+51.4%-$0.20+45.9%-$0.09+81.6%-$0.44-25.7%-$0.37-42.3%-$0.37+9.8%-$0.49+27.9%-$0.35+36.4%
EPS (Diluted)-$0.18-$0.20-$0.09-$0.44-25.7%-$0.37-42.3%-$0.37+9.8%-$0.49+27.9%-$0.35+36.4%
Diluted Shares (Avg)131M126MN/A73M+4.2%71M+3.2%71M+3.5%N/A70M+41.5%

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, Interest Expense.

CCCC Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CCCC quarterly balance sheet
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Total Assets$359.4M+21.2%$328.9M+2.9%$359.1M+2.7%$265.5M-29.4%$296.5M-22.2%$319.5M-19.8%$349.6M-7.1%$376.1M+12.9%
Current Assets$262.9M+17.0%$245.4M+5.5%$258.1M+0.1%$206.9M-24.3%$224.7M-18.6%$232.5M-16.8%$257.8M-4.9%$273.2M+22.1%
Cash & Equivalents$78.6M+0.6%$61.3M+19.5%$74.6M+34.4%$58.8M-1.4%$78.2M+6.9%$51.3M-42.8%$55.5M-56.2%$59.6M-2.2%
Short-Term Investments$175.1M+28.3%$174.4M+6.5%$173.9M-8.2%$133.1M-32.1%$136.4M-28.6%$163.8M-2.8%$189.4M+49.0%$196.0M+26.0%
Accounts Receivable$1.3M-38.2%$2.9M-64.1%$2.4M-22.6%$6.5M-36.7%$2.2M+84.9%$8.0M-41.0%$3.1M-73.7%$10.3M+1968.2%
Long-Term Investments$46.8M+455.7%$32.6M+66.2%$48.6M+117.2%$7.9M-72.6%$8.4M-73.4%$19.6M-52.1%$22.4M-20.2%$28.8M-3.7%
Total Liabilities$112.1M-8.4%$94.6M-23.9%$102.5M-23.3%$111.1M-16.7%$122.5M-8.6%$124.4M-11.2%$133.6M+2.5%$133.4M+14.0%
Current Liabilities$48.2M+8.5%$27.2M-33.2%$33.0M-26.9%$35.9M-17.0%$44.5M-18.0%$40.8M-25.8%$45.2M+5.6%$43.3M+43.0%
Non-Current Liabilities$63.9M-18.1%$67.4M-19.4%$69.5M-21.5%$75.1M-16.6%$78.0M-2.3%$83.6M-1.8%$88.4M+1.0%$90.1M+3.9%
Total Equity$247.3M+42.1%$234.2M+20.0%$256.6M+18.8%$154.4M-36.4%$174.1M-29.5%$195.1M-24.4%$216.0M-12.2%$242.7M+12.3%
Retained Earnings-$787.5M-14.8%-$763.8M-15.7%-$738.7M-16.6%-$718.2M-19.9%-$686.0M-19.4%-$660.0M-18.6%-$633.7M-19.9%-$599.1M-21.4%

Not reported in any period shown, so not listed: Inventory, Goodwill, Long-Term Debt.

CCCC Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CCCC quarterly cash flow statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Cash Flow-$1.6M+86.9%-$29.9M+10.0%-$22.1M-23.5%-$31.2M-29.3%-$12.1M-142.4%-$33.3M-83.7%-$17.9M+25.3%-$24.1M+21.4%
Depreciation & Amortization$336K-19.2%$404K-11.4%$703K-0.8%$384K+5.2%$416K+40.5%$456K+1.8%$709K+64.9%$365K-18.3%
Stock-Based Compensation$3.0M-39.2%$2.7M-51.5%N/A$4.6M-48.0%$5.0M-21.8%$5.5M-11.4%N/A$8.8M+7.7%
Capital Expenditures$37K-80.0%$64K$11K+175.0%$411K+3061.5%$185K-6.1%$0-$4K-97.5%-$13K-97.8%
Free Cash Flow-$1.6M+86.8%-$30.0M+9.8%-$22.2M-23.5%-$31.6M-30.9%-$12.2M-136.7%-$33.3M-83.7%-$17.9M+25.8%-$24.1M+22.9%
Investing Cash Flow-$14.8M-138.1%$16.2M-44.5%-$80.7M-690.6%$4.1M+2422.2%$38.9M+432.5%$29.1M+154.5%$13.7M-57.2%$162K-99.7%
Financing Cash Flow$33.7M$462K+1104.3%$118.7M+105857.1%$7.8M-26.0%$0-100.0%-$46K-100.1%$112K-99.8%$10.5M+197.7%
Share Buybacks$0$200K+29.0%$14K$24K-71.8%$0$155K+42.2%$0$85K+431.3%

Not reported in any period shown, so not listed: Dividends Paid.

CCCC Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CCCC quarterly financial ratios
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Margin-397.9%-451.6%-210.1%-306.4%-441.0%-402.9%-728.4%-183.9%
Net Margin-355.9%-408.5%-186.0%-286.4%-402.6%-363.7%-667.8%-160.6%
Return on Equity-9.6%+5.4pp-10.7%+2.8pp-8.0%+8.0pp-20.8%-10.7pp-14.9%-7.8pp-13.5%-2.5pp-16.0%-1.9pp-10.2%+2.4pp
Return on Assets-6.6%+2.2pp-7.6%+0.6pp-5.7%+4.2pp-12.1%-5.6pp-8.8%-4.1pp-8.2%-1.1pp-9.9%-0.7pp-6.6%+1.6pp
Current Ratio5.45+0.4x9.00+3.3x7.81+2.1x5.75-0.6x5.060.0x5.70+0.6x5.71-0.6x6.31-1.1x
Debt-to-Equity0.45-0.3x0.40-0.2x0.40-0.2x0.72+0.2x0.70+0.2x0.64+0.1x0.62+0.6x0.55+0.5x
Asset Turnover0.020.0x0.020.0x0.030.0x0.040.0x0.020.0x0.020.0x0.010.0x0.040.0x
FCF Margin-24.3%-487.8%-201.1%-281.6%-189.4%-459.9%-346.5%-157.2%

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
C4 Therapeutics, Inc. CCCC FY2025 $35.9M -$105.0M N/A $388.8M 65/100
Entrada Therapeutics, Inc. TRDA FY2025 $25.4M -$143.8M N/A $220.8M 41/100
Innate Pharma S.A. IPHA FY2025 $50.0M N/A N/A $181.0M —
Elicio Therapeutics, Inc. ELTX FY2025 N/A -$39.6M N/A $49.7M —
NeOnc Technologies Holdings, Inc. NTHI FY2025 $40K N/A N/A $80.1M —
SELLAS Life Sciences Group, Inc. SLS FY2025 N/A -$26.9M N/A $2.4B —

Frequently Asked Questions

What is C4 Therapeutics, Inc.'s annual revenue?

C4 Therapeutics, Inc. (CCCC) reported $35.9M in total revenue for fiscal year 2025. This represents a 1.0% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is C4 Therapeutics, Inc.'s revenue growing?

C4 Therapeutics, Inc. (CCCC) revenue grew by 1.0% year-over-year, from $35.6M to $35.9M in fiscal year 2025.

Is C4 Therapeutics, Inc. profitable?

No, C4 Therapeutics, Inc. (CCCC) reported a net income of -$105.0M in fiscal year 2025.

C4 Therapeutics, Inc. (CCCC) reported diluted earnings per share of -$1.27 for fiscal year 2025. This represents a 16.4% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

C4 Therapeutics, Inc. (CCCC) had EBITDA of -$113.3M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

C4 Therapeutics, Inc. (CCCC) has a return on equity of -40.9% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

C4 Therapeutics, Inc. (CCCC) recorded an outflow of $99.3M in free cash flow during fiscal year 2025. This represents a -52.0% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

C4 Therapeutics, Inc. (CCCC) recorded an outflow of $98.7M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

C4 Therapeutics, Inc. (CCCC) had $359.1M in total assets as of fiscal year 2025, including both current and long-term assets.

C4 Therapeutics, Inc. (CCCC) invested $607K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

C4 Therapeutics, Inc. (CCCC) invested $104.2M in research and development during fiscal year 2025.

Yes, C4 Therapeutics, Inc. (CCCC) spent $193K on share buybacks during fiscal year 2025, returning capital to shareholders by reducing shares outstanding.

C4 Therapeutics, Inc. (CCCC) had 98M shares outstanding as of fiscal year 2025.

C4 Therapeutics, Inc. (CCCC) had a current ratio of 7.81 as of fiscal year 2025, which is generally considered healthy.

C4 Therapeutics, Inc. (CCCC) had a debt-to-equity ratio of 0.40 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

C4 Therapeutics, Inc. (CCCC) had a return on assets of -29.2% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

C4 Therapeutics, Inc. (CCCC) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (trailing 12 months to June 30, 2026). The market capitalization is $388.8M as of Oct 10, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

C4 Therapeutics, Inc. (CCCC) trades at 11.1x sales, its market capitalization divided by revenue of $35.0M revenue, trailing 12 months to June 30, 2026. The market capitalization is $388.8M as of Oct 10, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

At the end of fiscal year 2025, C4 Therapeutics, Inc. (CCCC) held $297.1M in cash, cash equivalents and investments, and reported an operating cash outflow of $98.7M over that year. Dividing the one by the other, the reported balance equals about 36 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

C4 Therapeutics, Inc. (CCCC) has an Altman Z-Score of -0.81, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

C4 Therapeutics, Inc. (CCCC) has a Piotroski F-Score of 3 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

C4 Therapeutics, Inc. (CCCC) reported a net loss of $105.0M while operations used $98.7M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

C4 Therapeutics, Inc. (CCCC) scores 65 out of 100 on our Financial Health Score, indicating strong standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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