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Cryoport Inc Financials

CYRX
Source SEC Filings (10-K/10-Q) Updated Dec 31, 2025 Currency USD FYE December

This page shows Cryoport Inc (CYRX) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 15 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 28 / 100
Financial Profile 28/100

Based on FY2025 annual data, averaged across the last 3 years for performance metrics (most-recent year weighted highest). How this score is calculated →

Health score ≠ stock price. This rates the quality of Cryoport Inc's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Profitability
0

Cryoport Inc has an operating margin of -20.9%, meaning the company retains $-21 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses. This is up from -77.6% the prior year.

Growth
37

Cryoport Inc's revenue grew 12.4% year-over-year to $176.2M, a solid pace of expansion. This earns a growth score of 37/100.

Leverage
91

Cryoport Inc carries a low D/E ratio of 0.52, meaning only $0.52 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 91/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
40

Cryoport Inc's current ratio of 2.17 indicates adequate short-term liquidity, earning a score of 40/100. The company can meet its near-term obligations, though with limited headroom.

Cash Flow
0

While Cryoport Inc generated -$8.6M in operating cash flow, capex of $16.4M consumed most of it, leaving -$25.0M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.

Returns
0

Cryoport Inc generates a 15.6% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100. This is up from -28.5% the prior year.

Piotroski F-Score Neutral
5/9

Cryoport Inc passes 5 of 9 financial strength tests. 2 of 4 profitability signals pass, 1 of 3 leverage/liquidity signals pass, both operating efficiency signals pass.

Earnings Quality Low Quality
-0.11x

For every $1 of reported earnings, Cryoport Inc generates $-0.11 in operating cash flow (-$8.6M OCF vs $78.3M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Interest Coverage At Risk
-15.6x

Cryoport Inc earns $-15.6 in operating income for every $1 of interest expense (-$36.8M vs $2.4M). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$176.2M
YoY+12.4%
5Y CAGR+17.5%
10Y CAGR+46.3%

Cryoport Inc generated $176.2M in revenue in fiscal year 2025. This represents an increase of 12.4% from the prior year.

EBITDA
-$9.1M
YoY+90.0%

Cryoport Inc's EBITDA was -$9.1M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 90.0% from the prior year.

Net Income
$78.3M
YoY+168.2%

Cryoport Inc reported $78.3M in net income in fiscal year 2025. This represents an increase of 168.2% from the prior year.

EPS (Diluted)
$1.40
YoY+156.2%

Cryoport Inc earned $1.40 per diluted share (EPS) in fiscal year 2025. This represents an increase of 156.2% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$25.0M
YoY+25.5%

Cryoport Inc generated -$25.0M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 25.5% from the prior year.

Cash & Debt
$250.5M
YoY+633.8%
5Y CAGR+46.7%
10Y CAGR+67.9%

Cryoport Inc held $250.5M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
50M
YoY-0.1%
5Y CAGR+4.6%

Cryoport Inc had 50M shares outstanding in fiscal year 2025. This represents a decrease of 0.1% from the prior year.

Margins & Returns

Gross Margin
47.1%
YoY+2.7pp
5Y CAGR+1.0pp
10Y CAGR+17.4pp

Cryoport Inc's gross margin was 47.1% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. This is up 2.7 percentage points from the prior year.

Operating Margin
-20.9%
YoY+56.7pp
5Y CAGR+17.2pp
10Y CAGR+121.2pp

Cryoport Inc's operating margin was -20.9% in fiscal year 2025, reflecting core business profitability. This is up 56.7 percentage points from the prior year.

Net Margin
44.4%
YoY+117.6pp
5Y CAGR+86.0pp
10Y CAGR+223.0pp

Cryoport Inc's net profit margin was 44.4% in fiscal year 2025, showing the share of revenue converted to profit. This is up 117.6 percentage points from the prior year.

Return on Equity
15.6%
YoY+44.1pp
5Y CAGR+24.1pp

Cryoport Inc's ROE was 15.6% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 44.1 percentage points from the prior year.

Capital Allocation

R&D Spending
$17.0M
YoY-3.8%
5Y CAGR+12.4%
10Y CAGR+47.4%

Cryoport Inc invested $17.0M in research and development in fiscal year 2025. This represents a decrease of 3.8% from the prior year.

Share Buybacks
$10.0M

Cryoport Inc spent $10.0M on share buybacks in fiscal year 2025, returning capital to shareholders by reducing shares outstanding.

Capital Expenditures
$16.4M
YoY-4.7%
5Y CAGR+13.0%
10Y CAGR+72.6%

Cryoport Inc invested $16.4M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 4.7% from the prior year.

CYRX Income Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Revenue $45.5M+2.8% $44.2M-2.7% $45.5M+10.8% $41.0M-1.0% $41.5M+8.2% $38.3M-3.5% $39.7M+6.5% $37.3M
Cost of Revenue $23.7M+3.6% $22.9M-4.9% $24.1M+7.5% $22.4M+2.0% $22.0M+5.2% $20.9M-5.3% $22.0M-0.8% $22.2M
Gross Profit $21.7M+1.8% $21.3M-0.2% $21.4M+14.7% $18.6M-4.4% $19.5M+11.8% $17.4M-1.3% $17.7M+17.2% $15.1M
R&D Expenses $4.5M-1.3% $4.5M+9.8% $4.1M+4.7% $3.9M-5.3% $4.2M0.0% $4.2M-10.5% $4.6M-2.2% $4.8M
SG&A Expenses $25.0M-6.5% $26.7M-0.6% $26.9M+11.2% $24.2M-13.9% $28.1M+5.3% $26.7M-2.1% $27.2M-2.1% $27.8M
Operating Income -$7.7M+22.1% -$9.9M-2.9% -$9.6M-1.7% -$9.5M+25.6% -$12.7M+4.8% -$13.4M+82.8% -$78.0M-345.7% -$17.5M
Interest Expense $634K+20.5% $526K-14.9% $618K+6.0% $583K+13.0% $516K-41.5% $882K-28.9% $1.2M-7.2% $1.3M
Income Tax $1.1M+582.4% $165K-39.8% $274K+17.1% $234K+274.6% -$134K-142.4% $316K+378.8% $66K-40.5% $111K
Net Income -$8.0M-14.6% -$6.9M-106.6% $105.2M+977.9% -$12.0M+35.9% -$18.7M-2420.1% $805K+101.0% -$78.0M-312.7% -$18.9M
EPS (Diluted) N/A $-0.18-108.8% $2.05+832.1% $-0.28 N/A $-0.02+98.8% $-1.62-276.7% $-0.43

CYRX Balance Sheet

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Total Assets $765.0M-1.2% $774.3M+0.1% $773.9M+10.6% $699.8M-0.5% $703.5M+0.2% $701.8M-17.7% $852.3M-9.6% $942.8M
Current Assets $476.2M-1.8% $484.8M-0.9% $489.5M+19.0% $411.3M+20.4% $341.6M-2.5% $350.3M-30.2% $502.0M-4.5% $525.7M
Cash & Equivalents $250.5M-2.1% $255.8M+5.1% $243.4M+574.2% $36.1M+5.8% $34.1M+8.8% $31.4M-8.2% $34.2M-13.0% $39.3M
Inventory $23.2M-0.6% $23.3M+1.3% $23.0M-1.3% $23.3M+8.7% $21.5M-8.8% $23.6M-0.2% $23.6M-5.6% $25.0M
Accounts Receivable $33.4M-4.5% $34.9M+4.5% $33.4M+17.8% $28.4M+12.1% $25.3M-41.8% $43.5M+8.2% $40.2M-2.6% $41.3M
Goodwill $22.4M0.0% $22.4M+19.8% $18.7M-10.7% $21.0M+1.9% $20.6M-61.9% $54.1M+3.2% $52.4M-51.3% $107.6M
Total Liabilities $262.4M+0.5% $261.1M+1.0% $258.5M-14.1% $301.0M-0.2% $301.6M+6.5% $283.2M-37.4% $452.2M-3.9% $470.7M
Current Liabilities $219.0M+612.3% $30.7M+2.0% $30.1M-59.3% $74.0M+14.7% $64.6M+5.1% $61.4M+2.6% $59.9M+22.3% $49.0M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $502.6M-2.1% $513.3M-1.1% $519.1M+30.2% $398.8M-0.8% $401.9M-4.0% $418.6M+4.6% $400.1M-15.3% $472.2M
Retained Earnings -$688.9M-2.0% -$675.2M-1.0% -$668.2M+13.1% -$769.2M-1.6% -$757.2M-2.5% -$738.5M+0.1% -$739.3M-11.8% -$661.3M

CYRX Cash Flow Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Operating Cash Flow $919K-58.0% $2.2M+129.8% -$7.3M-69.2% -$4.3M+20.8% -$5.5M-1326.0% $447K+105.6% -$8.0M-145.8% -$3.3M
Capital Expenditures $5.5M+58.3% $3.5M-20.6% $4.4M+37.3% $3.2M-39.3% $5.2M+23.1% $4.2M+11.8% $3.8M-5.4% $4.0M
Free Cash Flow -$4.5M-259.5% -$1.3M+89.2% -$11.7M-55.7% -$7.5M+29.8% -$10.7M-182.1% -$3.8M+67.9% -$11.8M-62.5% -$7.3M
Investing Cash Flow $56K-99.6% $14.3M-93.8% $230.0M+3784.5% $5.9M+70.2% $3.5M-97.7% $153.6M+1052.8% $13.3M+106.7% $6.4M
Financing Cash Flow -$2.2M+24.9% -$2.9M+81.9% -$15.9M-8293.7% -$189K-109.4% $2.0M+101.3% -$155.3M-1671.9% -$8.8M-1811.7% $512K
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks $2.0M-46.4% $3.7M N/A N/A N/A N/A N/A N/A

CYRX Financial Ratios

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Gross Margin 47.8%-0.4pp 48.2%+1.2pp 47.0%+1.6pp 45.4%-1.6pp 47.0%+1.5pp 45.5%+1.0pp 44.5%+4.1pp 40.4%
Operating Margin -17.0%+5.4pp -22.4%-1.2pp -21.2%+1.9pp -23.1%+7.6pp -30.8%+4.2pp -34.9%+161.6pp -196.5%-149.6pp -46.9%
Net Margin -17.5%-1.8pp -15.7%-247.1pp 231.4%+260.6pp -29.2%+15.9pp -45.1%-47.2pp 2.1%+198.5pp -196.4%-145.7pp -50.7%
Return on Equity -1.6%-0.2pp -1.4%-21.6pp 20.3%+23.3pp -3.0%+1.6pp -4.6%-4.8pp 0.2%+19.7pp -19.5%-15.5pp -4.0%
Return on Assets -1.0%-0.1pp -0.9%-14.5pp 13.6%+15.3pp -1.7%+0.9pp -2.6%-2.8pp 0.1%+9.3pp -9.2%-7.1pp -2.0%
Current Ratio 2.17-13.6 15.77-0.5 16.24+10.7 5.56+0.3 5.29-0.4 5.70-2.7 8.38-2.4 10.73
Debt-to-Equity 0.52+0.0 0.51+0.0 0.50-0.3 0.750.0 0.75+0.1 0.68-0.5 1.13+0.1 1.00
FCF Margin -10.0%-7.1pp -2.9%+22.9pp -25.7%-7.4pp -18.3%+7.5pp -25.8%-15.9pp -9.9%+19.8pp -29.8%-10.2pp -19.5%

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Frequently Asked Questions

Cryoport Inc (CYRX) reported $176.2M in total revenue for fiscal year 2025. This represents a 12.4% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Cryoport Inc (CYRX) revenue grew by 12.4% year-over-year, from $156.8M to $176.2M in fiscal year 2025.

Yes, Cryoport Inc (CYRX) reported a net income of $78.3M in fiscal year 2025, with a net profit margin of 44.4%.

Cryoport Inc (CYRX) reported diluted earnings per share of $1.40 for fiscal year 2025. This represents a 156.2% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Cryoport Inc (CYRX) had EBITDA of -$9.1M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Cryoport Inc (CYRX) had a gross margin of 47.1% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.

Cryoport Inc (CYRX) had an operating margin of -20.9% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Cryoport Inc (CYRX) had a net profit margin of 44.4% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Cryoport Inc (CYRX) has a return on equity of 15.6% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Cryoport Inc (CYRX) generated -$25.0M in free cash flow during fiscal year 2025. This represents a 25.5% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Cryoport Inc (CYRX) generated -$8.6M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Cryoport Inc (CYRX) had $765.0M in total assets as of fiscal year 2025, including both current and long-term assets.

Cryoport Inc (CYRX) invested $16.4M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Cryoport Inc (CYRX) invested $17.0M in research and development during fiscal year 2025.

Yes, Cryoport Inc (CYRX) spent $10.0M on share buybacks during fiscal year 2025, returning capital to shareholders by reducing shares outstanding.

Cryoport Inc (CYRX) had 50M shares outstanding as of fiscal year 2025.

Cryoport Inc (CYRX) had a current ratio of 2.17 as of fiscal year 2025, which is generally considered healthy.

Cryoport Inc (CYRX) had a debt-to-equity ratio of 0.52 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Cryoport Inc (CYRX) had a return on assets of 10.2% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Cryoport Inc (CYRX) had $250.5M in cash against an annual operating cash burn of $8.6M. This gives an estimated cash runway of approximately 350 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Cryoport Inc (CYRX) has a Piotroski F-Score of 5 out of 9, indicating neutral financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Cryoport Inc (CYRX) has an earnings quality ratio of -0.11x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Cryoport Inc (CYRX) has an interest coverage ratio of -15.6x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Cryoport Inc (CYRX) scores 28 out of 100 on our Financial Profile, indicating weak overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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