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Entero Therapeutics Financials

ENTO
FY2025 annual
Revenue $36K YoY not available
Net Income -$6.4M +64.6% YoY
EPS (Diluted) -$4.16 YoY not available
Free Cash Flow Not reported for FY2025
Source SEC Filings (10-K/10-Q) Data as of Mar 31, 2026 Currency USD FYE December

Entero Therapeutics (ENTO) reported $36K in revenue for fiscal year 2025. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 11 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ENTO FY2025

Entero now looks like a development-stage company whose main operating mechanic is cash burn funded by fresh financing rather than product revenue.

FY2025’s net loss narrowed to -$6.4M and operating cash burn improved to -$5.7M, but near-term liquidity still worsened sharply as the current ratio fell from 3.0x in FY2024 to 0.2x and cash ended at just $900K. That combination suggests the income statement improved faster than the balance sheet’s ability to absorb ongoing burn, so access to funding remained central to operations.

With only $36K of revenue against $694K of cost of revenue, the business was not being supported by commercial sales in FY2025. SG&A of $5.5M was far larger than R&D of $925K, which means the current cash profile reflects maintaining the corporate platform more than scaling a revenue engine.

The balance sheet looked stronger on paper than the cash position alone would imply: total equity was $24.9M, but roughly $24.1M of assets were goodwill while cash was under $1.0M. That helps explain why FY2025 financing inflows of $5.9M were almost a one-for-one replacement for cash used in operations.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Financial health score not available

Entero Therapeutics does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.

Altman Z-Score Distress
-6.67

Entero Therapeutics scores -6.67, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($4.7M) relative to total liabilities ($19.7M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
2/6

Entero Therapeutics passes 2 of 6 computable financial strength tests (3 of the nine could not be computed from available data). 2 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution).

Earnings Quality No Cash Backing
N/A

Entero Therapeutics reported a net loss of $6.4M while operations used $5.7M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$36K

Entero Therapeutics generated $36K in revenue in fiscal year 2025.

EBITDA
-$6.5M
YoY+58.2%

Entero Therapeutics's EBITDA was -$6.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 58.2% from the prior year.

Net Income
-$6.4M
YoY+64.6%

Entero Therapeutics reported -$6.4M in net income in fiscal year 2025. This represents an increase of 64.6% from the prior year.

EPS (Diluted)
-$4.16

Entero Therapeutics earned -$4.16 per diluted share (EPS) in fiscal year 2025.

Cash & Balance Sheet

Cash & Debt
$900K
YoY+450.4%
5Y CAGR-31.7%
10Y CAGR+4.5%

Entero Therapeutics held $900K in cash as of fiscal year 2025; long-term debt is not reported for that period.

Shares Outstanding
3M

Entero Therapeutics had 3M shares outstanding in fiscal year 2025.

Free Cash Flow

Not reported for fiscal year 2025.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Return on Equity
-25.6%

Entero Therapeutics's ROE was -25.6% in fiscal year 2025, measuring profit generated per dollar of shareholder equity.

Gross Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$925K
YoY+2.4%
5Y CAGR-30.9%
10Y CAGR-4.0%

Entero Therapeutics invested $925K in research and development in fiscal year 2025. This represents an increase of 2.4% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

Capital Expenditures

Not reported for fiscal year 2025.

ENTO Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ENTO annual income statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15
RevenueN/A$36KN/AN/AN/AN/AN/A$0$0N/AN/AN/A
Cost of RevenueN/A$694KN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Gross ProfitN/A-$657KN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
R&D ExpensesN/A$925K+2.4%$904K-82.0%$5.0M-42.6%$8.8M-48.4%$17.0M+188.6%$5.9M-32.2%$8.7M+50.4%$5.8M+140.9%$2.4M-4.0%$2.5M+78.5%$1.4M
SG&A ExpensesN/A$5.5M-62.6%$14.7M+37.1%$10.7M-10.4%$12.0M-34.8%$18.4M+152.0%$7.3M+20.3%$6.1M-18.6%$7.5M-3.1%$7.7M+86.1%$4.1M+24.0%$3.3M
Operating IncomeN/A-$7.1M+54.7%-$15.6M+0.9%-$15.8M-24.4%-$12.7MN/A-$26.4M-79.3%-$14.7M-9.8%-$13.4M-31.4%-$10.2M-61.6%-$6.3M-33.8%-$4.7M
Interest ExpenseN/AN/AN/A$22K+41.5%$16K+41.3%$11K-99.8%$5.8M+1246.0%$434K+326.1%$102K-88.4%$875K-85.3%$5.9M+274.0%$1.6M
Income TaxN/A-$399KN/AN/AN/A$0$0$0N/A$0$0$0
Net IncomeN/A-$6.4M+64.6%-$18.1M-14.3%-$15.8M-8.0%-$14.6M+75.0%-$58.5M-79.2%-$32.7M-115.3%-$15.2M-12.1%-$13.5M-22.0%-$11.1M+24.0%-$14.6M-146.1%-$5.9M
EPS (Diluted)-$4.16-$15.99-$47.88-$416.94+79.0%-$1988.53-$14.68N/AN/AN/AN/AN/A

TTM is the trailing twelve months, Q2 FY2025 through Q1 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

ENTO Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ENTO annual balance sheet
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15
Total Assets$48.6M-43.2%$85.4M+1140.8%$6.9M+26.5%$5.4M-53.9%$11.8M-8.8%$12.9M+45.2%$8.9M+19.2%$7.5M+36.3%$5.5M-18.9%$6.8M+1.0%$6.7M
Current Assets$2.6M-96.9%$83.5M+1584.3%$5.0M+45.2%$3.4M-63.8%$9.4M+19.8%$7.9M+130.9%$3.4M-29.0%$4.8M+145.8%$2.0M-34.1%$3.0M+43.4%$2.1M
Cash & Equivalents$900K+450.4%$163K-95.6%$3.7M+172.3%$1.4M-83.5%$8.2M+36.1%$6.1M+3348.4%$176K-84.2%$1.1M+94.3%$573K$0-100.0%$582K
Accounts Receivable$30KN/AN/A$93K$0-100.0%$551K-79.1%$2.6M-16.9%$3.2M+187.3%$1.1M+14.9%$961K-10.6%$1.1M
Goodwill$24.1M+1332.1%$1.7M0.0%$1.7M0.0%$1.7M-11.9%$1.9M-6.9%$2.1M+8.9%$1.9M-2.0%$1.9M-4.5%$2.0M+14.1%$1.8M-3.5%$1.8M
Total Liabilities$19.7M-77.9%$89.3M+2621.9%$3.3M+21.6%$2.7M-86.2%$19.6M+26.0%$15.6M+263.2%$4.3M+43.1%$3.0M-21.6%$3.8M+7.9%$3.5M-65.7%$10.3M
Current Liabilities$15.2M-45.0%$27.5M+779.1%$3.1M+26.2%$2.5M-79.8%$12.3M-20.9%$15.5M+262.7%$4.3M+43.1%$3.0M+20.8%$2.5M+5.9%$2.3M-73.4%$8.8M
Total Equity$24.9M+743.4%-$3.9M-207.6%$3.6M+31.4%$2.7M+135.1%-$7.8M-196.2%-$2.6M-157.2%$4.6M+3.2%$4.5M+169.4%$1.7M-48.3%$3.2M+188.5%-$3.6M
Retained Earnings-$208.8M-3.2%-$202.4M-9.8%-$184.3M-9.4%-$168.5M-9.5%-$153.9M-61.4%-$95.4M-52.1%-$62.7M-31.9%-$47.5M-39.8%-$34.0M-48.5%-$22.9M-175.9%-$8.3M

Not reported in any period shown, so not listed: Inventory, Long-Term Debt.

ENTO Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ENTO annual cash flow statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15
Operating Cash Flow-$6.7M-$5.7M+38.1%-$9.2M+25.5%-$12.4M+44.6%-$22.3M+30.8%-$32.3M-187.7%-$11.2M+20.0%-$14.0M-29.1%-$10.9M-51.3%-$7.2M-58.4%-$4.5M-8.7%-$4.2M
Capital ExpendituresN/AN/AN/AN/AN/A$69K+1567.6%$4K-82.7%$24K-56.6%$55K+72.4%$32K+160.4%$12K-49.3%$24K
Free Cash FlowN/AN/AN/AN/AN/A-$32.4M-188.2%-$11.2M+20.1%-$14.1M-28.7%-$10.9M-51.4%-$7.2M-58.7%-$4.5M-8.4%-$4.2M
Investing Cash FlowN/A$323K+266.9%$88K+117.6%-$500KN/A-$10.3M-11914.0%$87K+462.5%-$24K+92.1%-$305K-849.6%-$32K-160.4%-$12K+49.3%-$24K
Financing Cash Flow$6.6M$5.9M+5.5%$5.6M-63.3%$15.2M-3.3%$15.7M-64.8%$44.8M+162.6%$17.0M+29.7%$13.1M+12.2%$11.7M+94.8%$6.0M+4.6%$5.7M+22.8%$4.7M

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

TTM is the trailing twelve months, Q2 FY2025 through Q1 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

ENTO Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

ENTO annual financial ratios
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15
Gross Margin-1813.6%N/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Operating Margin-19540.0%N/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Net Margin-17634.4%N/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Return on Equity-25.6%N/A-438.4%+95.1pp-533.5%N/AN/A-328.7%-26.2pp-302.5%+365.7pp-668.2%-214.1pp-454.1%N/A
Return on Assets-13.2%+8.0pp-21.1%+208.3pp-229.5%+39.5pp-268.9%+227.6pp-496.5%-243.7pp-252.8%-82.3pp-170.5%+10.7pp-181.2%+21.3pp-202.5%+13.5pp-216.0%-127.3pp-88.7%
Current Ratio0.17-2.9x3.03+1.4x1.58+0.2x1.37+0.6x0.77+0.3x0.51-0.3x0.80-0.8x1.60+0.8x0.79-0.5x1.27+1.0x0.23
Debt-to-Equity0.79N/A0.91-0.1x0.98N/AN/A0.93+0.3x0.67-1.6x2.30+1.2x1.10N/A

Not reported in any period shown, so not listed: FCF Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Gross Margin, Operating Margin, Net Margin.

Note: The current ratio is below 1.0 (0.17), indicating current liabilities exceed current assets, which may suggest potential short-term liquidity concerns.

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Frequently Asked Questions

What is Entero Therapeutics's annual revenue?

Entero Therapeutics (ENTO) reported $36K in total revenue for fiscal year 2025. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Is Entero Therapeutics profitable?

No, Entero Therapeutics (ENTO) reported a net income of -$6.4M in fiscal year 2025.

What is Entero Therapeutics's earnings per share (EPS)?

Entero Therapeutics (ENTO) reported diluted earnings per share of -$4.16 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Entero Therapeutics (ENTO) had EBITDA of -$6.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Entero Therapeutics (ENTO) has a return on equity of -25.6% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Entero Therapeutics (ENTO) recorded an outflow of $5.7M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Entero Therapeutics (ENTO) had $48.6M in total assets as of fiscal year 2025, including both current and long-term assets.

Entero Therapeutics (ENTO) invested $925K in research and development during fiscal year 2025.

Entero Therapeutics (ENTO) had 3M shares outstanding as of fiscal year 2025.

Entero Therapeutics (ENTO) had a current ratio of 0.17 as of fiscal year 2025, which is below 1.0, which may suggest potential liquidity concerns.

Entero Therapeutics (ENTO) had a debt-to-equity ratio of 0.79 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Entero Therapeutics (ENTO) had a return on assets of -13.2% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Entero Therapeutics (ENTO) had $900K in cash against an annual operating cash burn of $5.7M. This gives an estimated cash runway of approximately 2 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Entero Therapeutics (ENTO) has an Altman Z-Score of -6.67, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Entero Therapeutics (ENTO) has a Piotroski F-Score of 2 out of 6 computable signals; 3 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Entero Therapeutics (ENTO) reported a net loss of $6.4M while operations used $5.7M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

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