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Guardant Health Financials

GH
Source SEC Filings (10-K/10-Q) Updated Dec 31, 2025 Currency USD FYE December

This page shows Guardant Health (GH) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 9 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 46 / 100
Financial Profile 46/100

Based on FY2025 annual data. Scores normalized against common benchmarks. How we calculate these scores

Profitability
0

Guardant Health has an operating margin of -44.5%, meaning the company retains $-45 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses. This is up from -60.0% the prior year.

Growth
88

Guardant Health's revenue surged 32.9% year-over-year to $982.0M, reflecting rapid business expansion. This strong growth earns a score of 88/100.

Liquidity
97

With a current ratio of 4.84, Guardant Health holds $4.84 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 97/100.

Cash Flow
0

While Guardant Health generated -$184.8M in operating cash flow, capex of $48.3M consumed most of it, leaving -$233.1M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.

Piotroski F-Score Neutral
5/9

Guardant Health passes 5 of 9 financial strength tests. 2 of 4 profitability signals pass, 2 of 3 leverage/liquidity signals pass, 1 of 2 efficiency signals pass.

Earnings Quality Low Quality
0.44x

For every $1 of reported earnings, Guardant Health generates $0.44 in operating cash flow (-$184.8M OCF vs -$416.3M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Interest Coverage At Risk
-112.2x

Guardant Health earns $-112.2 in operating income for every $1 of interest expense (-$437.2M vs $3.9M). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$982.0M
YoY+32.9%
5Y CAGR+27.9%

Guardant Health generated $982.0M in revenue in fiscal year 2025. This represents an increase of 32.9% from the prior year.

EBITDA
-$397.5M
YoY+0.9%

Guardant Health's EBITDA was -$397.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 0.9% from the prior year.

Net Income
-$416.3M
YoY+4.6%

Guardant Health reported -$416.3M in net income in fiscal year 2025. This represents an increase of 4.6% from the prior year.

EPS (Diluted)
$-3.32
YoY+6.7%

Guardant Health earned $-3.32 per diluted share (EPS) in fiscal year 2025. This represents an increase of 6.7% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$233.1M
YoY+15.2%

Guardant Health generated -$233.1M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 15.2% from the prior year.

Cash & Debt
$378.2M
YoY-28.0%
5Y CAGR-14.6%

Guardant Health held $378.2M in cash against $1.5B in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
131M
YoY+6.3%
5Y CAGR+5.5%

Guardant Health had 131M shares outstanding in fiscal year 2025. This represents an increase of 6.3% from the prior year.

Margins & Returns

Gross Margin
64.5%
YoY+3.7pp

Guardant Health's gross margin was 64.5% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. This is up 3.7 percentage points from the prior year.

Operating Margin
-44.5%
YoY+15.5pp
5Y CAGR+44.4pp

Guardant Health's operating margin was -44.5% in fiscal year 2025, reflecting core business profitability. This is up 15.5 percentage points from the prior year.

Net Margin
-42.4%
YoY+16.7pp
5Y CAGR+43.5pp

Guardant Health's net profit margin was -42.4% in fiscal year 2025, showing the share of revenue converted to profit. This is up 16.7 percentage points from the prior year.

Return on Equity
N/A

Capital Allocation

R&D Spending
$364.2M
YoY+4.7%
5Y CAGR+19.4%

Guardant Health invested $364.2M in research and development in fiscal year 2025. This represents an increase of 4.7% from the prior year.

Share Buybacks
$45.0M

Guardant Health spent $45.0M on share buybacks in fiscal year 2025, returning capital to shareholders by reducing shares outstanding.

Capital Expenditures
$48.3M
YoY+37.7%
5Y CAGR+6.0%

Guardant Health invested $48.3M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 37.7% from the prior year.

GH Income Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Revenue $281.3M+6.1% $265.2M+14.3% $232.1M+14.1% $203.5M+0.8% $201.8M+5.4% $191.5M+8.0% $177.2M+5.2% $168.5M
Cost of Revenue $99.5M+6.3% $93.6M+15.2% $81.2M+8.7% $74.7M-3.7% $77.6M+4.2% $74.5M+2.9% $72.4M+10.9% $65.3M
Gross Profit $181.8M+5.9% $171.6M+13.7% $150.9M+17.2% $128.7M+3.6% $124.2M+6.2% $117.0M+11.6% $104.8M+1.6% $103.2M
R&D Expenses $98.3M+9.2% $90.0M+2.9% $87.4M-1.2% $88.5M-5.4% $93.5M+7.1% $87.3M+5.1% $83.1M-0.8% $83.8M
SG&A Expenses $60.9M+14.4% $53.3M+6.0% $50.3M+7.0% $47.0M-9.5% $51.9M+5.6% $49.1M+21.4% $40.5M+4.7% $38.7M
Operating Income -$120.8M-22.0% -$99.0M+7.0% -$106.4M+4.2% -$111.0M+11.8% -$126.0M-7.4% -$117.3M-16.6% -$100.6M-0.9% -$99.7M
Interest Expense $1.2M+25.1% $943K-4.1% $983K+24.3% $791K+22.4% $646K+0.2% $645K0.0% $645K0.0% $645K
Income Tax -$1.7M-1369.9% $136K+257.9% $38K-86.9% $290K-59.5% $716K+2286.7% $30K-77.4% $133K-67.2% $405K
Net Income -$128.5M-38.6% -$92.7M+7.2% -$99.9M-5.0% -$95.2M+14.3% -$111.0M-3.0% -$107.8M-5.0% -$102.6M+10.7% -$115.0M
EPS (Diluted) N/A $-0.74+7.5% $-0.80-3.9% $-0.77 N/A $-0.88-4.8% $-0.84+10.6% $-0.94

GH Balance Sheet

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Total Assets $2.0B+57.7% $1.3B-4.1% $1.3B-0.9% $1.3B-9.5% $1.5B-3.5% $1.5B-4.4% $1.6B-5.6% $1.7B
Current Assets $1.5B+76.9% $828.9M-6.2% $883.4M-4.7% $927.0M-12.1% $1.1B-14.0% $1.2B-4.9% $1.3B-1.4% $1.3B
Cash & Equivalents $378.2M-34.8% $580.0M-7.8% $629.1M-9.9% $698.6M+32.9% $525.5M-10.2% $585.0M-37.3% $933.7M-9.3% $1.0B
Inventory $85.9M-5.1% $90.5M+7.6% $84.1M+8.8% $77.3M+8.7% $71.1M-1.7% $72.3M+7.9% $67.0M+6.3% $63.0M
Accounts Receivable $137.8M+19.3% $115.6M-11.3% $130.3M+12.8% $115.4M+4.7% $110.3M+24.6% $88.5M-12.0% $100.5M+18.9% $84.6M
Goodwill $77.3M+2248.2% $3.3M0.0% $3.3M0.0% $3.3M0.0% $3.3M0.0% $3.3M0.0% $3.3M0.0% $3.3M
Total Liabilities $2.1B+29.5% $1.6B-0.4% $1.6B+2.7% $1.6B-1.9% $1.6B+1.7% $1.6B-0.8% $1.6B-1.5% $1.6B
Current Liabilities $302.7M+27.8% $236.9M-0.6% $238.4M+5.6% $225.8M+0.1% $225.6M+14.3% $197.3M-2.1% $201.6M-8.4% $220.0M
Long-Term Debt $1.5B+34.9% $1.1B-0.1% $1.1B-0.1% $1.1B-2.3% $1.1B N/A N/A N/A
Total Equity -$99.3M+72.0% -$354.5M-16.0% -$305.5M-21.8% -$250.8M-79.6% -$139.6M-132.4% -$60.1M-3625.7% -$1.6M-102.4% $68.3M
Retained Earnings -$3.0B-4.5% -$2.9B-3.3% -$2.8B-3.7% -$2.7B-3.7% -$2.6B-4.5% -$2.5B-4.6% -$2.4B-4.5% -$2.3B

GH Cash Flow Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Operating Cash Flow -$26.4M+25.5% -$35.4M+41.3% -$60.3M+3.8% -$62.7M+2.8% -$64.5M-26.3% -$51.1M+45.7% -$94.0M-210.4% -$30.3M
Capital Expenditures $27.8M+169.1% $10.3M+83.2% $5.6M+26.7% $4.5M-76.4% $18.9M+349.5% $4.2M-17.3% $5.1M-26.8% $6.9M
Free Cash Flow -$54.2M-18.5% -$45.8M+30.6% -$65.9M+1.8% -$67.1M+19.5% -$83.4M-50.9% -$55.3M+44.2% -$99.1M-166.2% -$37.2M
Investing Cash Flow -$905.1M-6207.1% -$14.3M-34.8% -$10.6M-103.5% $302.9M+2776.2% $10.5M+103.6% -$294.8M-5707.1% -$5.1M-118.1% $28.1M
Financing Cash Flow $732.0M+16802.1% $4.3M+166.7% $1.6M+102.4% -$66.8M-2177.7% -$2.9M-1.7% -$2.9M-148.9% $5.9M+649.2% -$1.1M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks $0 $0 $0-100.0% $45.0M $0 $0 $0 $0

GH Financial Ratios

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Gross Margin 64.6%-0.1pp 64.7%-0.3pp 65.0%+1.7pp 63.3%+1.7pp 61.6%+0.5pp 61.1%+2.0pp 59.1%-2.1pp 61.3%
Operating Margin -43.0%-5.6pp -37.3%+8.5pp -45.9%+8.7pp -54.6%+7.9pp -62.4%-1.1pp -61.3%-4.5pp -56.8%+2.4pp -59.2%
Net Margin -45.7%-10.7pp -35.0%+8.1pp -43.0%+3.7pp -46.8%+8.2pp -55.0%+1.3pp -56.3%+1.6pp -57.9%+10.3pp -68.2%
Return on Equity N/A N/A N/A N/A N/A N/A N/A -168.4%
Return on Assets -6.4%+0.9pp -7.3%+0.2pp -7.5%-0.4pp -7.1%+0.4pp -7.5%-0.5pp -7.0%-0.6pp -6.4%+0.4pp -6.8%
Current Ratio 4.84+1.3 3.50-0.2 3.71-0.4 4.11-0.6 4.68-1.5 6.22-0.2 6.40+0.5 5.95
Debt-to-Equity -15.14-12.0 -3.14+0.5 -3.65+0.8 -4.45+3.7 -8.18+18.4 -26.60+972.1 -998.73-1022.7 23.96
FCF Margin -19.3%-2.0pp -17.3%+11.2pp -28.4%+4.6pp -33.0%+8.3pp -41.3%-12.5pp -28.9%+27.0pp -55.9%-33.8pp -22.1%

Note: Shareholder equity is negative (-$99.3M), which causes debt-to-equity and return on equity ratios to appear negative or not meaningful. This can occur from accumulated losses or large share buyback programs.

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Frequently Asked Questions

Guardant Health (GH) reported $982.0M in total revenue for fiscal year 2025. This represents a 32.9% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Guardant Health (GH) revenue grew by 32.9% year-over-year, from $739.0M to $982.0M in fiscal year 2025.

No, Guardant Health (GH) reported a net income of -$416.3M in fiscal year 2025, with a net profit margin of -42.4%.

Guardant Health (GH) reported diluted earnings per share of $-3.32 for fiscal year 2025. This represents a 6.7% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Guardant Health (GH) had EBITDA of -$397.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Guardant Health (GH) had $378.2M in cash and equivalents against $1.5B in long-term debt.

Guardant Health (GH) had a gross margin of 64.5% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.

Guardant Health (GH) had an operating margin of -44.5% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Guardant Health (GH) had a net profit margin of -42.4% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Guardant Health (GH) generated -$233.1M in free cash flow during fiscal year 2025. This represents a 15.2% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Guardant Health (GH) generated -$184.8M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Guardant Health (GH) had $2.0B in total assets as of fiscal year 2025, including both current and long-term assets.

Guardant Health (GH) invested $48.3M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Guardant Health (GH) invested $364.2M in research and development during fiscal year 2025.

Yes, Guardant Health (GH) spent $45.0M on share buybacks during fiscal year 2025, returning capital to shareholders by reducing shares outstanding.

Guardant Health (GH) had 131M shares outstanding as of fiscal year 2025.

Guardant Health (GH) had a current ratio of 4.84 as of fiscal year 2025, which is generally considered healthy.

Guardant Health (GH) had a debt-to-equity ratio of -15.14 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Guardant Health (GH) had a return on assets of -20.7% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Guardant Health (GH) had $378.2M in cash against an annual operating cash burn of $184.8M. This gives an estimated cash runway of approximately 25 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Guardant Health (GH) has negative shareholder equity of -$99.3M as of fiscal year 2025, which causes the debt-to-equity ratio to appear negative or not meaningful. This can occur when accumulated losses exceed invested capital, or after large share buyback programs. Other solvency metrics like the current ratio or interest coverage may be more informative.

Guardant Health (GH) has a Piotroski F-Score of 5 out of 9, indicating neutral financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Guardant Health (GH) has an earnings quality ratio of 0.44x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Guardant Health (GH) has an interest coverage ratio of -112.2x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Guardant Health (GH) scores 46 out of 100 on our Financial Profile, indicating moderate overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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