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Nautilus Biotechnolgy (NAUT) Financials

NAUT NASDAQ
Trailing 12 months to September 30, 2026
Net Income -$58.6M n/m YoY
EPS (Diluted) -$0.46 n/m YoY
Free Cash Flow -$55.1M n/m YoY
Operating Cash Flow -$52.5M n/m YoY
Market Cap $291.7M as of Nov 4, 2026
Price / Sales n/m no revenue reported
Price / Earnings n/m net loss, so no earnings multiple, trailing 12 months to September 30, 2026
Price / Book 2.5x on $116.6M equity, Q3 FY2026

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Nov 4, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings (10-K/10-Q) Latest period Q3 FY2026, ended Sep 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q3 FY2026, filed Oct 27, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the NAUT SEC filings page.

This page shows Nautilus Biotechnolgy, Inc. (NAUT) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI NAUT FY2025

Research funding still drives the business, while lower spending narrows losses as a shrinking asset base makes liabilities more prominent.

Cash conversion was relatively close in FY2025: net loss was $59.0M while operating cash flow was -$50.7M, indicating the reported loss largely translated into cash outflow. Free cash flow was -$52.0M, slightly below operating cash flow, showing that capital spending added to the cash burden rather than losses being purely non-cash.

FY2025 research and development was $41.1M and selling, general and administrative expense was $25.7M, keeping internal investment and overhead as the main uses of the operating budget. Both declined year over year—R&D by 18.6% and SG&A by 17.0%—while the net loss narrowed from $70.8M to $59.0M, linking expense reduction with improved reported earnings.

Total assets fell from $242.7M in FY2024 to $191.1M in FY2025, reducing the balance-sheet cushion. Liabilities were broadly unchanged at $34.0M and $34.1M, so their share of assets rose from 14.0% to 17.9%: the structure became relatively more liability-weighted even without a large absolute increase in liabilities.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Financial health score not available

We do not publish a peer-relative financial health score for Nautilus Biotechnolgy, Inc., because the score only covers companies whose filings and listing give us what it needs to compare them with their peers. The signals and metrics below are current.

Piotroski F-Score Partial
1/6

Nautilus Biotechnolgy, Inc. passes 1 of 6 computable financial strength tests (3 of the nine could not be computed from available data). 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution).

Earnings Quality No Cash Backing
N/A

Nautilus Biotechnolgy, Inc. reported a net loss of $59.0M while operations used $50.7M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$234K
YoYn/m
QoQ+23.2%

Nautilus Biotechnolgy, Inc. generated $234K in revenue in Q3 2026. The change from the same quarter a year earlier is not meaningful, because that figure was zero or negative. Against the prior quarter it is up 23.2%.

Net Income
-$15.6M
YoYn/m
QoQn/m
5Y CAGRn/m

Nautilus Biotechnolgy, Inc. reported a net loss of $15.6M in Q3 2026. The change from the same quarter a year earlier is not meaningful, because that figure was zero or negative. The change from the prior quarter is not meaningful, because that quarter’s figure was zero or negative.

EPS (Diluted)
-$0.12
YoYn/m
QoQn/m
5Y CAGRn/m

Nautilus Biotechnolgy, Inc. earned -$0.12 per diluted share (EPS) in Q3 2026. The change from the same quarter a year earlier is not meaningful, because that figure was zero or negative. The change from the prior quarter is not meaningful, because that quarter’s figure was zero or negative.

EBITDA

Not reported for Q3 2026.

Cash & Balance Sheet

Free Cash Flow
-$14.7M
YoYn/m
QoQn/m
5Y CAGRn/m

Nautilus Biotechnolgy, Inc. recorded an outflow of $14.7M in free cash flow in Q3 2026, representing a cash shortfall after capex. The change from the same quarter a year earlier is not meaningful, because that figure was zero or negative. The change from the prior quarter is not meaningful, because that quarter’s figure was zero or negative.

Cash & Debt
$10.5M
YoY-56.2%
QoQ-20.5%
5Y CAGR-44.0%

Nautilus Biotechnolgy, Inc. held $10.5M in cash as of Q3 2026; no long-term debt figure is on record for that period.

Shares Outstanding
127M
YoY+0.8%
QoQ+0.1%
5Y CAGR+0.5%

Nautilus Biotechnolgy, Inc. had 127M shares outstanding in Q3 2026. This represents an increase of 0.8% from the same quarter a year earlier. Against the prior quarter it is up 0.1%.

Dividends Per Share

Not reported for Q3 2026.

Margins & Returns

Gross Margin
89.7%
QoQ-2.4pp

Nautilus Biotechnolgy, Inc.'s gross margin was 89.7% in Q3 2026, indicating the percentage of revenue retained after direct costs. Against the prior quarter it is down 2.4 percentage points.

Return on Equity
-13.4%
YoY-5.4pp
QoQ-2.4pp
5Y change-9.6pp

Nautilus Biotechnolgy, Inc.'s quarterly ROE was -13.4% in Q3 2026: one quarter's net income over shareholder equity, not annualized. This is down 5.4 percentage points from the same quarter a year earlier. Against the prior quarter it is down 2.4 percentage points.

Operating Margin

Not reported for Q3 2026.

Net Margin

Not shown for Q3 2026: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$10.2M
YoY+5.9%
QoQ+5.9%
5Y CAGR+4.3%

Nautilus Biotechnolgy, Inc. invested $10.2M in research and development in Q3 2026. This represents an increase of 5.9% from the same quarter a year earlier. Against the prior quarter it is up 5.9%.

Capital Expenditures
$1.4M
YoY+245.7%
QoQ+218.3%
5Y CAGR+39.9%

Nautilus Biotechnolgy, Inc. invested $1.4M in capex in Q3 2026, funding long-term assets and infrastructure. This represents an increase of 245.7% from the same quarter a year earlier. Against the prior quarter it is up 218.3%.

Share Buybacks

Not reported for Q3 2026.

NAUT Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

NAUT quarterly income statement
MetricQ3'2610-QQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-K
Revenue$234Kn/m$190Kn/mN/AN/A$0$0N/AN/A
Cost of Revenue$24Kn/m$15Kn/mN/AN/A$0$0N/AN/A
Gross Profit$210Kn/m$175Kn/mN/AN/A$0$0N/AN/A
R&D Expenses$10.2M+5.9%$9.6M-7.5%$9.7M-15.9%$9.6M-25.3%$9.6M-21.8%$10.4M-16.4%$11.5M-10.8%$12.8M+2.9%
SG&A Expenses$6.8M+15.4%$6.3M-5.6%$6.4M-12.2%$5.8M-18.3%$5.9M-13.9%$6.7M-19.8%$7.3M-15.8%$7.2M-5.0%
Income Tax$0n/m$0n/m$0n/m$0n/m$0n/m$0n/m$0n/m$0n/m
Net Income-$15.6Mn/m-$14.5Mn/m-$14.7Mn/m-$13.8Mn/m-$13.6Mn/m-$15.0Mn/m-$16.6Mn/m-$17.6Mn/m
EPS (Basic)-$0.12n/m-$0.11n/m-$0.12n/m-$0.11n/m-$0.11n/m-$0.12n/m-$0.13n/m-$0.14n/m
EPS (Diluted)-$0.12n/m-$0.11n/m-$0.12n/m-$0.11n/m-$0.11n/m-$0.12n/m-$0.13n/m-$0.14n/m
Diluted Shares (Avg)127M+0.7%127M+0.7%127M+0.4%N/A126M+0.7%126M+0.7%126M+0.8%N/A

Not reported in any period shown, so not listed: Operating Income, EBITDA, Interest Expense.

NAUT Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

NAUT quarterly balance sheet
MetricQ3'2610-QQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-K
Total Assets$148.9M-25.9%$163.6M-23.3%$177.8M-21.9%$191.1M-21.3%$200.9M-22.6%$213.2M-21.8%$227.7M-21.1%$242.7M-20.6%
Current Assets$90.2M-32.8%$87.6M-41.9%$98.8M-30.2%$106.0M-20.2%$134.3M-6.9%$150.7M-11.8%$141.6M-23.5%$132.8M-24.9%
Cash & Equivalents$10.5M-56.2%$13.2M-61.8%$14.6M-56.0%$12.4M-55.2%$23.9M+441.5%$34.5M+38.5%$33.2M+29.2%$27.6M+42.5%
Short-Term Investments$76.1M-29.2%$70.9M-37.5%$81.2M-23.0%$91.0M-11.0%$107.6M-21.0%$113.4M-20.4%$105.6M-32.2%$102.2M-33.6%
Inventory$900K$600K$300KN/AN/AN/AN/AN/A
Long-Term Investments$27.8M-25.1%$45.2M+42.7%$47.5M-12.1%$52.7M-31.0%$37.1M-54.0%$31.6M-51.7%$54.0M-18.5%$76.4M-15.7%
Total Liabilities$32.4M+1.9%$32.5M+1.1%$33.4M+0.3%$34.1M+0.4%$31.8M-12.4%$32.1M-14.3%$33.3M-15.1%$34.0M-15.4%
Current Liabilities$9.8M+8.6%$8.6M+6.2%$8.3M+2.3%$8.0M+4.2%$9.0M+3.7%$8.1M-6.3%$8.2M-11.5%$7.6M-16.3%
Non-Current Liabilities$22.6M-0.8%$23.8M-0.6%$25.0M-0.3%$26.2M-0.7%$22.8M-17.4%$24.0M-16.8%$25.1M-16.2%$26.4M-15.1%
Total Equity$116.6M-31.1%$131.1M-27.6%$144.4M-25.7%$157.0M-24.8%$169.1M-24.3%$181.1M-23.0%$194.4M-22.1%$208.7M-21.3%
Retained Earnings-$376.8Mn/m-$361.2Mn/m-$346.7Mn/m-$332.0Mn/m-$318.2Mn/m-$304.7Mn/m-$289.6Mn/m-$273.0Mn/m

Not reported in any period shown, so not listed: Accounts Receivable, Goodwill, Long-Term Debt.

NAUT Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

NAUT quarterly cash flow statement
MetricQ3'2610-QQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-K
Operating Cash Flow-$13.3Mn/m-$13.7Mn/m-$13.1Mn/m-$12.4Mn/m-$11.0Mn/m-$13.3Mn/m-$13.9Mn/m-$14.3Mn/m
Depreciation & Amortization$200K-50.0%$300K-25.0%$334K-28.2%$400K-12.5%$400K-20.0%$400K-20.0%$465K-9.9%$457K-17.7%
Stock-Based CompensationN/AN/A$1.4M-37.2%N/AN/AN/A$2.2M-30.4%N/A
Capital Expenditures$1.4M+245.7%$454K+14.6%$510K+132.9%$244K-3.9%$418K-41.0%$396K-22.7%$219K-66.2%$254K-38.5%
Free Cash Flow-$14.7Mn/m-$14.2Mn/m-$13.6Mn/m-$12.6Mn/m-$11.5Mn/m-$13.7Mn/m-$14.2Mn/m-$14.6Mn/m
Investing Cash Flow$10.4M+2209.3%$12.0M-16.9%$14.2M-27.1%$787K-97.9%$452Kn/m$14.5M+1.3%$19.5M-12.7%$37.1Mn/m
Financing Cash Flow$26Kn/m$244K+156.8%$1.1M+6038.9%$101K-77.0%$0-100.0%$95K-70.2%$18K-92.7%$440K+73.9%

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

NAUT Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

NAUT quarterly financial ratios
MetricQ3'2610-QQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-K
Gross Margin89.7%92.1%N/AN/AN/AN/AN/AN/A
Net Margin-6682.1%-7615.3%N/AN/AN/AN/AN/AN/A
Return on Equity-13.4%-5.4pp-11.0%-2.7pp-10.2%-1.6pp-8.8%-0.4pp-8.0%-0.7pp-8.3%-0.7pp-8.5%-1.0pp-8.4%-2.0pp
Return on Assets-10.5%-3.7pp-8.8%-1.8pp-8.3%-1.0pp-7.2%0.0pp-6.8%-0.4pp-7.0%-0.4pp-7.3%-0.8pp-7.2%-1.7pp
Current Ratio9.25-5.7x10.14-8.4x11.85-5.5x13.33-4.1x14.95-1.7x18.52-1.2x17.36-2.7x17.40-2.0x
Liabilities-to-Equity0.28+0.1x0.25+0.1x0.23+0.1x0.22+0.1x0.190.0x0.180.0x0.170.0x0.160.0x
Asset Turnover0.000.0x0.000.0xN/AN/A0.000.00N/AN/A
FCF Margin-6293.2%-7463.2%N/AN/AN/AN/AN/AN/A

Not reported in any period shown, so not listed: Operating Margin, Debt-to-Equity.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Net Margin, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it. Market cap is stated at each company's latest close.

Company Fiscal year Revenue Net income Net margin Market cap Health score
Nautilus Biotechnolgy, Inc. NAUT FY2025 N/A -$59.0M N/A $291.7M —
Turn Therapeutics Inc. TTRX FY2025 N/A -$3.2M N/A $297.6M —
Century Therapeutics, Inc. IPSC FY2025 $109.2M -$9.6M -8.8% $302.4M 60/100
Fulcrum Therapeutics, Inc. FULC FY2025 $0 -$74.9M N/A $288.0M —
SAB Biotherapeutics, Inc. SABS FY2025 $0 $13.3M N/A $289.3M —
Rocket Pharmaceuticals, Inc. RCKT FY2025 $0 -$223.1M N/A $286.5M —

Frequently Asked Questions

No, Nautilus Biotechnolgy, Inc. (NAUT) reported a net loss of $58.6M over the trailing 12 months to September 30, 2026. In fiscal year 2025 it reported a net loss of $59.0M.

Nautilus Biotechnolgy, Inc. (NAUT) reported diluted earnings per share of -$0.47 for fiscal year 2025. The change from the previous fiscal year is not meaningful, because that year’s figure was zero or negative. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Nautilus Biotechnolgy, Inc. (NAUT) has a return on equity of -37.6% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Nautilus Biotechnolgy, Inc. (NAUT) recorded an outflow of $52.0M in free cash flow during fiscal year 2025. The change from the previous fiscal year is not meaningful, because that year’s figure was zero or negative. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Nautilus Biotechnolgy, Inc. (NAUT) recorded an outflow of $50.7M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Nautilus Biotechnolgy, Inc. (NAUT) had $191.1M in total assets as of fiscal year 2025, including both current and long-term assets.

Nautilus Biotechnolgy, Inc. (NAUT) invested $1.3M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Nautilus Biotechnolgy, Inc. (NAUT) invested $41.1M in research and development during fiscal year 2025.

Nautilus Biotechnolgy, Inc. (NAUT) had 127M shares outstanding as of fiscal year 2025.

Nautilus Biotechnolgy, Inc. (NAUT) had a current ratio of 13.33 as of fiscal year 2025, which is generally considered healthy.

Nautilus Biotechnolgy, Inc. (NAUT) had a liabilities-to-equity ratio of 0.22 as of fiscal year 2025, which is total liabilities divided by total shareholder equity. Total liabilities counts every obligation on the balance sheet (payables, deposits, insurance reserves and deferred taxes as well as borrowings), so this ratio usually runs well above debt-to-equity. No debt-to-equity ratio is shown for fiscal year 2025, because the filing data we hold for that year carries no long-term debt figure.

Nautilus Biotechnolgy, Inc. (NAUT) had a return on assets of -30.9% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Nautilus Biotechnolgy, Inc. (NAUT) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (trailing 12 months to September 30, 2026). The market capitalization is $291.7M as of Nov 4, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

Nautilus Biotechnolgy, Inc. (NAUT) has no price-to-sales ratio at the moment: no revenue reported. The market capitalization is $291.7M as of Nov 4, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

At the end of fiscal year 2025, Nautilus Biotechnolgy, Inc. (NAUT) held $156.1M in cash, cash equivalents and investments, and reported an operating cash outflow of $50.7M over that year. Dividing the one by the other, the reported balance equals about 37 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Nautilus Biotechnolgy, Inc. (NAUT) has a Piotroski F-Score of 1 out of 6 computable signals; 3 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Nautilus Biotechnolgy, Inc. (NAUT) reported a net loss of $59.0M while operations used $50.7M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

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