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Palisade Bio Inc Financials

PALI
FY2025 annual
Revenue $0 YoY not available
Net Income -$16.8M -16.2% YoY
EPS (Diluted) -$0.30 YoY not available
Free Cash Flow Not reported for FY2025
Source SEC Filings (10-K/10-Q) Data as of Jun 30, 2026 Currency USD FYE December

Palisade Bio Inc (PALI) reported $0 in revenue for fiscal year 2025. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 15 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI PALI FY2025

Financing-built liquidity supports Palisade Bio while a development-stage cost structure continues to consume operating cash.

Cash rose from $9.8M in FY2024 to $133.4M in FY2025 even as operating cash flow remained -$10.8M, so the balance-sheet expansion did not come from operating activity. Financing cash flow supplied $134.4M in FY2025 while liabilities were only $5.0M, indicating that the enlarged cash position is primarily an equity-funded reserve rather than internally generated liquidity.

In FY2023, R&D spending was $6.9M against $250K of revenue, showing spending far ahead of recorded commercial scale. R&D reached $10.2M in FY2025 while operating loss was -$18.1M, making development investment a principal cost driver.

Debt-to-equity fell from 0.5x in FY2024 to 0.0x in FY2025, shifting the capital structure away from borrowing. FY2025 liabilities were $5.0M against $133.4M of cash, leaving liquidity concentrated in cash rather than debt-funded assets.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Financial health score not available

Palisade Bio Inc does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.

Piotroski F-Score Partial
3/7

Palisade Bio Inc passes 3 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 2 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality No Cash Backing
N/A

Palisade Bio Inc reported a net loss of $16.8M while operations used $10.8M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Palisade Bio Inc reported an operating loss of $18.1M against $10K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

Revenue
$0

Palisade Bio Inc generated $0 in revenue in fiscal year 2025.

EBITDA
-$18.1M
YoY-21.5%

Palisade Bio Inc's EBITDA was -$18.1M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 21.5% from the prior year.

Net Income
-$16.8M
YoY-16.2%

Palisade Bio Inc reported -$16.8M in net income in fiscal year 2025. This represents a decrease of 16.2% from the prior year.

EPS (Diluted)
-$0.30

Palisade Bio Inc earned -$0.30 per diluted share (EPS) in fiscal year 2025.

Cash & Balance Sheet

Cash & Debt
$133.4M
YoY+1258.2%
5Y CAGR+184.7%
10Y CAGR+39.7%

Palisade Bio Inc held $133.4M in cash as of fiscal year 2025; long-term debt is not reported for that period.

Shares Outstanding
159M

Palisade Bio Inc had 159M shares outstanding in fiscal year 2025.

Free Cash Flow

Not reported for fiscal year 2025.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Return on Equity
-13.0%
YoY+179.7pp

Palisade Bio Inc's ROE was -13.0% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 179.7 percentage points from the prior year.

Gross Margin

Not reported for fiscal year 2025.

Operating Margin

Not reported for fiscal year 2025.

Net Margin

Not reported for fiscal year 2025.

Capital Allocation

R&D Spending
$10.2M
YoY-36.3%
5Y CAGR+38.2%
10Y CAGR-2.1%

Palisade Bio Inc invested $10.2M in research and development in fiscal year 2025. This represents a decrease of 36.3% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

Capital Expenditures

Not reported for fiscal year 2025.

PALI Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

PALI annual income statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
RevenueN/A$0$0-100.0%$250K$0N/A$14K-12.2%$15K-94.1%$260K0.0%$260K+1500.4%$16K+56.0%$10K-44.7%$19K-82.9%$110K-73.0%$408K+4.4%$391K
R&D ExpensesN/A$10.2M-36.3%$16.0M+132.1%$6.9M+5.3%$6.5M+169.4%$2.4M+20.4%$2.0M-50.3%$4.1M+2.6%$4.0M-51.1%$8.1M-38.5%$13.2M+4.1%$12.6M+51.1%$8.4M+14.8%$7.3M+19.3%$6.1M-17.0%$7.4M
SG&A ExpensesN/A$7.9M+35.7%$5.8M-6.5%$6.2M-29.2%$8.8M-5.8%$9.3M+50.2%$6.2M+35.2%$4.6M+0.6%$4.6M-16.7%$5.5M-27.0%$7.5M+14.8%$6.5M-28.2%$9.1M+70.0%$5.3M+1989.1%$256K0.0%$256K
Operating IncomeN/A-$18.1M-21.5%-$14.9M-13.7%-$13.1M+16.9%-$15.7M+62.4%-$41.9M-350.2%-$9.3M-7.7%-$8.6M-4.5%-$8.3M+37.9%-$13.3M+35.5%-$20.6M-7.7%-$19.2M-9.9%-$17.4M-39.2%-$12.5M-23.3%-$10.2M+21.8%-$13.0M
Interest ExpenseN/A$10K-16.7%$12K-20.0%$15K+15.4%$13K-99.5%$2.4M+920.4%$235K+2534.5%$9K+15.9%$8K-95.2%$159K-86.1%$1.1M-37.2%$1.8M+12.1%$1.6M+16.2%$1.4M+51558.9%$3K+228.7%$821
Income TaxN/A$0$0$0$0$0-100.0%$1KN/AN/AN/A$0$0$0$0$0$0
Net IncomeN/A-$16.8M-16.2%-$14.4M-17.4%-$12.3M+13.7%-$14.3M+46.4%-$26.6M-157.9%-$10.3M-23.6%-$8.4M-69.6%-$4.9M+68.6%-$15.7M+25.7%-$21.1M-0.8%-$20.9M+7.6%-$22.6M-14.1%-$19.8M-95.9%-$10.1M+19.1%-$12.5M
EPS (Diluted)-$0.30-$10.19-$27.01-$16.53-$169.74-$3.72N/AN/AN/AN/AN/AN/AN/AN/AN/A

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

PALI Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

PALI annual balance sheet
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Total Assets$134.3M+1134.8%$10.9M-22.6%$14.1M-10.9%$15.8M+26.0%$12.5M+314.4%$3.0M-54.1%$6.6M-14.3%$7.7M-44.7%$13.9M-38.6%$22.6M+51.2%$14.9M-49.9%$29.8M+53.7%$19.4M+121.9%$8.8M+114.1%$4.1M
Current Assets$134.2M+1179.0%$10.5M-21.3%$13.3M-9.5%$14.7M+28.0%$11.5M+1184.2%$896K-84.1%$5.6M-13.2%$6.5M-47.7%$12.4M-40.4%$20.9M+55.6%$13.4M-52.3%$28.2M+59.8%$17.6M+130.2%$7.7M+153.7%$3.0M
Cash & Equivalents$133.4M+1258.2%$9.8M-21.0%$12.4M+0.4%$12.4M+18.0%$10.5M+1371.9%$713K-86.1%$5.1M-11.6%$5.8M-13.3%$6.7M-56.1%$15.2M+222.2%$4.7M-62.3%$12.5M-25.7%$16.8M+126.3%$7.4M+216.5%$2.4M
Accounts Receivable$0$0N/A$0$0-100.0%$59K+180.1%$21K-92.8%$294K-6.0%$313K+2881.6%$10K-71.9%$37K-83.5%$226K+2155.2%$10K+200.0%$3K-98.6%$234K
Total Liabilities$5.0M+46.5%$3.4M+23.7%$2.7M-16.6%$3.3M-36.2%$5.1M-73.8%$19.6M+31.5%$14.9M+812.3%$1.6M-69.6%$5.4M-52.4%$11.3M+12.9%$10.0M-17.7%$12.1M+10.3%$11.0M+518.6%$1.8M-26.7%$2.4M
Current Liabilities$4.6M+43.3%$3.2M+25.1%$2.6M-14.1%$3.0M+20.7%$2.5M-69.1%$8.1M+559.9%$1.2M+16.5%$1.1M-30.6%$1.5M-79.3%$7.3M+14.1%$6.4M+60.3%$4.0M-32.5%$5.9M+238.0%$1.8M-27.6%$2.4M
Long-Term DebtN/AN/AN/AN/A$0-100.0%$94KN/AN/AN/AN/A$3.4M-58.0%$8.1M+63.3%$4.9M$0N/A
Total Equity$129.4M+1626.9%$7.5M-33.8%$11.3M-9.3%$12.5M+69.4%$7.4M+144.4%-$16.6M-99.3%-$8.3M-237.7%$6.0M-29.0%$8.5M-24.8%$11.3M+128.1%$5.0M-72.0%$17.7M+110.5%$8.4M+20.7%$7.0M+320.1%$1.7M
Retained EarningsN/A$135.9M+11.9%$121.5M+11.3%$109.2M+15.4%$94.6M+239.1%-$68.0M+69.4%-$222.0M-3.9%-$213.6M-2.4%-$208.7M-8.1%-$193.0M-12.3%-$172.0M-13.8%-$151.1M-17.6%-$128.4M-18.3%-$108.6M-10.3%-$98.5M

Not reported in any period shown, so not listed: Inventory, Goodwill.

PALI Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

PALI annual cash flow statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Operating Cash Flow-$18.2M-$10.8M+11.0%-$12.2M-9.5%-$11.1M+16.7%-$13.4M+9.6%-$14.8M-209.8%-$4.8M+34.3%-$7.3M+5.7%-$7.7M+42.7%-$13.4M+14.1%-$15.6M+17.5%-$18.9M-61.7%-$11.7M-10.5%-$10.6M-24.9%-$8.5M-4.7%-$8.1M
Capital ExpendituresN/AN/A$0-100.0%$4K-60.0%$10K$0-100.0%$6KN/A$2K-85.0%$11K-88.4%$98K-44.4%$176K-15.2%$208K+65.8%$125K+219.6%$39K-80.0%$196K
Free Cash FlowN/AN/A-$12.2M-9.5%-$11.1M+16.7%-$13.4M+9.5%-$14.8M-209.4%-$4.8MN/A-$7.7M+42.7%-$13.4M+14.6%-$15.7M+17.8%-$19.1M-60.4%-$11.9M-11.2%-$10.7M-25.8%-$8.5M-2.7%-$8.3M
Investing Cash FlowN/AN/A$0+100.0%-$4K+60.0%-$10K+81.5%-$54K-800.0%-$6KN/A$5.0M+5414.7%-$94K-104.0%$2.4MN/AN/AN/A-$255K+47.0%-$481K
Financing Cash Flow$138.0M$134.4M+1303.0%$9.6M-14.3%$11.2M-26.7%$15.3M-38.0%$24.6M+1202.1%$1.9M-71.3%$6.6M+263.2%$1.8M-63.6%$5.0M-79.0%$23.7MN/AN/AN/A$13.8M+728.6%$1.7M

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

PALI Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

PALI annual financial ratios
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Operating MarginN/AN/A-5228.0%N/AN/A-68764.8%-56071.8%-3176.7%-5118.1%-127027.2%-183896.8%-92581.4%-11385.4%-2491.1%-3325.6%
Net MarginN/AN/A-4920.0%N/AN/A-76346.1%-54252.6%-1894.1%-6025.4%-129721.8%-200671.0%-120154.7%-18029.0%-2482.5%-3204.7%
Return on Equity-13.0%+179.7pp-192.7%-84.0pp-108.7%+5.6pp-114.3%+247.1pp-361.4%N/AN/A-81.4%+102.6pp-184.0%+2.0pp-186.0%+234.8pp-420.8%-293.1pp-127.7%+107.9pp-235.6%-90.4pp-145.2%+609.0pp-754.2%
Return on Assets-12.5%+120.2pp-132.7%-45.2pp-87.5%+2.9pp-90.5%+122.3pp-212.7%+129.2pp-341.9%-215.1pp-126.8%-62.8pp-64.1%+48.7pp-112.8%-19.6pp-93.2%+46.6pp-139.8%-64.0pp-75.8%+26.3pp-102.2%+13.5pp-115.7%+190.7pp-306.4%
Current Ratio28.95+25.7x3.24-1.9x5.15+0.3x4.89+0.3x4.61+4.5x0.11-4.5x4.61-1.6x6.19-2.0x8.22+5.4x2.85+0.8x2.09-4.9x7.03+4.1x2.97-1.4x4.36+3.1x1.24
Debt-to-Equity0.04-0.4x0.45+0.2x0.240.0x0.26+0.3x0.00N/AN/A0.27-0.4x0.63-0.4x0.99+0.3x0.68+0.2x0.45-0.1x0.59+0.6x0.00-1.5x1.46
FCF MarginN/AN/A-4454.8%N/AN/A-35310.7%N/A-2959.3%-5164.4%-96726.6%-183430.3%-63264.4%-9742.7%-2089.0%-2123.0%

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

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Frequently Asked Questions

What is Palisade Bio Inc's annual revenue?

Palisade Bio Inc (PALI) reported $0 in total revenue for fiscal year 2025. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Is Palisade Bio Inc profitable?

No, Palisade Bio Inc (PALI) reported a net income of -$16.8M in fiscal year 2025.

What is Palisade Bio Inc's earnings per share (EPS)?

Palisade Bio Inc (PALI) reported diluted earnings per share of -$0.30 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Palisade Bio Inc (PALI) had EBITDA of -$18.1M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Palisade Bio Inc (PALI) has a return on equity of -13.0% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Palisade Bio Inc (PALI) recorded an outflow of $10.8M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Palisade Bio Inc (PALI) had $134.3M in total assets as of fiscal year 2025, including both current and long-term assets.

Palisade Bio Inc (PALI) invested $10.2M in research and development during fiscal year 2025.

Palisade Bio Inc (PALI) had 159M shares outstanding as of fiscal year 2025.

Palisade Bio Inc (PALI) had a current ratio of 28.95 as of fiscal year 2025, which is generally considered healthy.

Palisade Bio Inc (PALI) had a debt-to-equity ratio of 0.04 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Palisade Bio Inc (PALI) had a return on assets of -12.5% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Palisade Bio Inc (PALI) had $133.4M in cash against an annual operating cash burn of $10.8M. This gives an estimated cash runway of approximately 148 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Palisade Bio Inc (PALI) has a Piotroski F-Score of 3 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Palisade Bio Inc (PALI) reported a net loss of $16.8M while operations used $10.8M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Palisade Bio Inc (PALI) reported an operating loss of $18.1M against $10K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

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