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Phio Pharmaceuticals Corp Financials

PHIO
Source SEC Filings (10-K/10-Q) Updated Dec 31, 2025 Currency USD FYE December

This page shows Phio Pharmaceuticals Corp (PHIO) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 23 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Piotroski F-Score Weak
2/9

Phio Pharmaceuticals Corp passes 2 of 9 financial strength tests. 2 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution).

Earnings Quality Low Quality
0.92x

For every $1 of reported earnings, Phio Pharmaceuticals Corp generates $0.92 in operating cash flow (-$8.0M OCF vs -$8.7M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Key Financial Metrics

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Earnings & Revenue

Revenue
N/A
EBITDA
-$9.2M
YoY-24.8%

Phio Pharmaceuticals Corp's EBITDA was -$9.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 24.8% from the prior year.

Net Income
-$8.7M
YoY-21.7%

Phio Pharmaceuticals Corp reported -$8.7M in net income in fiscal year 2025. This represents a decrease of 21.7% from the prior year.

EPS (Diluted)
N/A

Cash & Balance Sheet

Free Cash Flow
-$8.0M
YoY-12.3%

Phio Pharmaceuticals Corp generated -$8.0M in free cash flow in fiscal year 2025, representing cash available after capex. This represents a decrease of 12.3% from the prior year.

Cash & Debt
$21.0M
YoY+290.8%
5Y CAGR+8.0%
10Y CAGR+15.2%

Phio Pharmaceuticals Corp held $21.0M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
12M

Phio Pharmaceuticals Corp had 12M shares outstanding in fiscal year 2025. This represents an increase of 570.1% from the prior year.

Margins & Returns

Gross Margin
N/A
Operating Margin
N/A
Net Margin
N/A
Return on Equity
-43.2%
YoY+108.2pp
5Y CAGR+24.4pp
10Y CAGR+71.8pp

Phio Pharmaceuticals Corp's ROE was -43.2% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 108.2 percentage points from the prior year.

Capital Allocation

R&D Spending
$4.6M
YoY+26.8%
5Y CAGR+4.4%
10Y CAGR-4.0%

Phio Pharmaceuticals Corp invested $4.6M in research and development in fiscal year 2025. This represents an increase of 26.8% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$12K
YoY+1100.0%
5Y CAGR-8.8%
10Y CAGR-14.4%

Phio Pharmaceuticals Corp invested $12K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 1100.0% from the prior year.

PHIO Income Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A N/A
R&D Expenses N/A $1.2M+10.0% $1.1M+21.2% $886K N/A $644K-25.6% $866K-24.6% $1.1M
SG&A Expenses N/A $1.3M+7.2% $1.2M+25.3% $986K N/A $946K-9.7% $1.0M-1.2% $1.1M
Operating Income N/A -$2.5M-8.5% -$2.3M-23.3% -$1.9M N/A -$1.6M+16.9% -$1.9M+13.4% -$2.2M
Interest Expense N/A N/A N/A -$125K N/A N/A N/A -$53K
Income Tax N/A N/A N/A N/A N/A N/A N/A N/A
Net Income N/A -$2.4M-10.4% -$2.2M-22.4% -$1.8M N/A -$1.5M+17.4% -$1.8M+14.3% -$2.2M
EPS (Diluted) N/A N/A $-0.45-9.8% $-0.41 N/A $-1.54+57.5% $-3.62 $-0.47

PHIO Balance Sheet

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Total Assets $21.5M+86.8% $11.5M+1.8% $11.3M-15.9% $13.4M+134.2% $5.7M-2.2% $5.9M+10.7% $5.3M-22.7% $6.9M
Current Assets $21.5M+86.9% $11.5M+1.8% $11.3M-15.9% $13.4M+134.2% $5.7M-2.2% $5.9M+10.8% $5.3M-22.7% $6.8M
Cash & Equivalents $21.0M+96.5% $10.7M-0.6% $10.8M-18.9% $13.3M+146.7% $5.4M-0.1% $5.4M+14.7% $4.7M-27.4% $6.5M
Inventory N/A N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable N/A N/A N/A N/A N/A N/A N/A N/A
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $1.3M-19.6% $1.7M+38.1% $1.2M-5.0% $1.3M+25.1% $1.0M+10.4% $919K-39.7% $1.5M+21.9% $1.2M
Current Liabilities N/A N/A $1.2M-5.0% $1.3M+25.1% $1.0M+10.4% $919K-39.7% $1.5M+21.9% $1.2M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $20.1M+104.8% $9.8M-2.5% $10.1M-17.1% $12.2M+157.7% $4.7M-4.5% $4.9M+31.1% $3.8M-32.7% $5.6M
Retained Earnings -$155.1M-1.6% -$152.7M-1.6% -$150.3M-1.5% -$148.1M-1.2% -$146.4M-1.1% -$144.7M-1.1% -$143.2M-1.3% -$141.4M

PHIO Cash Flow Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Operating Cash Flow -$2.1M+0.3% -$2.1M+17.9% -$2.5M-99.2% -$1.3M+7.0% -$1.4M+29.8% -$2.0M-9.9% -$1.8M+11.6% -$2.0M
Capital Expenditures $0-100.0% $7K+133.3% $3K+50.0% $2K+100.0% $1K $0 $0 $0
Free Cash Flow -$2.1M+0.6% -$2.1M+17.7% -$2.5M-99.1% -$1.3M+6.9% -$1.4M+29.7% -$2.0M-9.9% -$1.8M+11.6% -$2.0M
Investing Cash Flow $0+100.0% -$7K-133.3% -$3K-50.0% -$2K-125.0% $8K $0 $0 $0
Financing Cash Flow $12.4M+513.5% $2.0M+4955.0% $40K-99.6% $9.2M+577.0% $1.4M-48.8% $2.6M $0+100.0% -$4K
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

PHIO Financial Ratios

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Gross Margin N/A N/A N/A N/A N/A N/A N/A N/A
Operating Margin N/A N/A N/A N/A N/A N/A N/A N/A
Net Margin N/A N/A N/A N/A N/A N/A N/A N/A
Return on Equity N/A -24.3%-2.8pp -21.5%-6.9pp -14.5% N/A -30.8%+18.1pp -48.9%-10.5pp -38.4%
Return on Assets N/A -20.8%-1.6pp -19.2%-6.0pp -13.2% N/A -26.0%+8.9pp -34.9%-3.4pp -31.4%
Current Ratio N/A N/A 9.36-1.2 10.58+4.9 5.65-0.7 6.38+2.9 3.47-2.0 5.48
Debt-to-Equity 0.07-0.1 0.17+0.0 0.12+0.0 0.10-0.1 0.21+0.0 0.19-0.2 0.40+0.2 0.22
FCF Margin N/A N/A N/A N/A N/A N/A N/A N/A

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Frequently Asked Questions

No, Phio Pharmaceuticals Corp (PHIO) reported a net income of -$8.7M in fiscal year 2025.

Phio Pharmaceuticals Corp (PHIO) had EBITDA of -$9.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Phio Pharmaceuticals Corp (PHIO) has a return on equity of -43.2% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Phio Pharmaceuticals Corp (PHIO) generated -$8.0M in free cash flow during fiscal year 2025. This represents a -12.3% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Phio Pharmaceuticals Corp (PHIO) generated -$8.0M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Phio Pharmaceuticals Corp (PHIO) had $21.5M in total assets as of fiscal year 2025, including both current and long-term assets.

Phio Pharmaceuticals Corp (PHIO) invested $12K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Phio Pharmaceuticals Corp (PHIO) invested $4.6M in research and development during fiscal year 2025.

Phio Pharmaceuticals Corp (PHIO) had 12M shares outstanding as of fiscal year 2025.

Phio Pharmaceuticals Corp (PHIO) had a debt-to-equity ratio of 0.07 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Phio Pharmaceuticals Corp (PHIO) had a return on assets of -40.5% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Phio Pharmaceuticals Corp (PHIO) had $21.0M in cash against an annual operating cash burn of $8.0M. This gives an estimated cash runway of approximately 32 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Phio Pharmaceuticals Corp (PHIO) has a Piotroski F-Score of 2 out of 9, indicating weak financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Phio Pharmaceuticals Corp (PHIO) has an earnings quality ratio of 0.92x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

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