Ascentage Pharma Reports Full Year 2025 Unaudited Financial Results and Provides Business Updates
Rhea-AI Summary
Ascentage Pharma (NASDAQ: AAPG) reported unaudited 2025 results: revenue US$82.1M (-41.5% YoY) and a loss of US$177.7M. Product sales rose as Olverembatinib reached US$62.2M (+80.6%) and Lisaftoclax generated US$10.1M after its July launch.
R&D was US$162.7M (+20.1%), selling/distribution US$50.6M (+80.4%), and cash was US$353.2M following 2025 equity offerings. Nine registrational Phase III trials are underway, several cleared by FDA and EMA.
Positive
- Olverembatinib sales +80.6% to US$62.2M
- Lisaftoclax initial sales of US$10.1M in five months
- Cash and bank balances US$353.2M (net IPO proceeds)
Negative
- Total revenue down 41.5% to US$82.1M
- Net loss widened to US$177.7M in 2025
- R&D expenses increased 20.1% to US$162.7M
- Selling and distribution expenses +80.4% to US$50.6M
Key Figures
Market Reality Check
Peers on Argus
AAPG is up 0.27% with very light volume, while peers like ARWR (+6.07%), ACAD (+3.18%) and ZLAB (+3.10%) show stronger gains. With no names in the momentum scanner, today’s setup appears more stock‑specific than a broad biotech rotation.
Previous Earnings Reports
| Date | Event | Sentiment | Move | Catalyst |
|---|---|---|---|---|
| Aug 20 | Interim earnings | Positive | +1.1% | H1 2025 update with strong olverembatinib growth and lisaftoclax approval. |
| Mar 27 | Annual earnings | Positive | +10.0% | FY 2024 results with large revenue jump and reduced net loss. |
Earnings releases have previously led to modestly positive one-day reactions on both observed occasions.
Recent earnings-related news shows Ascentage emphasizing rapid commercial growth for olverembatinib and the launch of lisaftoclax. On Mar 27, 2025, full-year 2024 results highlighted revenue of US$134.3 million and reduced losses, with a 9.96% positive price reaction. The Aug 20, 2025 interim update showed strong H1 olverembatinib growth and lisaftoclax approval, with a smaller 1.05% gain. Today’s full-year 2025 update continues these themes of commercial expansion alongside sizable losses.
Historical Comparison
In the past year, AAPG reported 2 earnings updates, averaging a 5.51% one-day move, both positive. Today’s full-year 2025 release extends the same commercialization and registrational‑trial storyline against a backdrop of larger losses.
Earnings news has tracked a progression from FY 2024’s revenue surge and narrowed loss, through H1 2025’s strong olverembatinib growth and lisaftoclax approval, to the current FY 2025 report detailing expanded product sales, nine registrational Phase III trials, and a significantly larger annual loss.
Market Pulse Summary
This announcement details strong operational momentum, with 2025 product sales reaching US$82.1 million and olverembatinib sales of US$62.2 million, alongside a widened annual loss of US$177.7 million. Nine registrational Phase III trials and new IND clearances underscore the late-stage pipeline. At the same time, expenses, particularly US$162.7 million in R&D, remain high. Investors may focus on trial readouts, commercialization progress for lisaftoclax, and how the US$353.2 million cash balance funds this strategy.
Key Terms
nrdl regulatory
bcr-abl1 medical
bcl-2 medical
nmpa regulatory
btk inhibitor medical
protac technical
AI-generated analysis. Not financial advice.
- Product sales and commercial rights revenues in 2025 increased
90% year-over-year to US$82.1 million (RMB574.1 million) - Sales of Olverembatinib increased
81% year-over-year to US$62.2 million (RMB435.3 million) - Sales of Lisaftoclax since launch during last five months of 2025 were US
$10.1 million (RMB 70.6 million) - Nine registrational Phase III clinical trials are in progress worldwide, including four cleared by FDA and EMA
- Chinese (Mandarin) investor event with simultaneous conference call and webcast at 10:00 am HKT on March 26, 2026 / 10:00 pm EDT on March 25, 2026; and English language investor webcast at 8:00 am EDT / 8:00 pm HKT on March 26, 2026
ROCKVILLE, Md. and SUZHOU, China, March 25, 2026 (GLOBE NEWSWIRE) -- Ascentage Pharma Group International (Ascentage Pharma) (NASDAQ: AAPG; HKEX: 6855) (referred hereinto as “Ascentage Pharma,” the “Company,” “we,” “us” or “our”), a global, commercial stage, integrated biopharmaceutical company engaged in the discovery, development and commercialization of novel, differentiated therapies to address unmet medical needs in cancer, today reported its unaudited financial results for the year ended December 31, 2025, and provided updates on key ongoing clinical programs and commercial activities.
Dr. Dajun Yang, Chairman and Chief Executive Officer of Ascentage Pharma, said, “2025 was a year of significant execution in advancing our mission to deliver innovative therapies to patients worldwide. We advanced our commercialization strategy as Olverembatinib gained significant traction after receiving NRDL coverage expansion, which has markedly enhanced affordability and accessibility for patients in China. We launched Lisaftoclax in China in late July 2025 shortly after receiving regulatory approval and are gaining market adoption as we actively pursue the inclusion of Lisaftoclax in China’s NRDL.”
Dr. Yang continued, “Multiple advancements are continuing across our de-risked late-stage pipeline. For our third-generation tyrosine kinase inhibitor Olverembatinib, three global registrational Phase III trials, of which two are U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA) cleared, are underway. Our Bcl-2 selective inhibitor, Lisaftoclax, with its highly differentiated daily dose ramp up, is being evaluated in ongoing global registrational Phase III trials, including two cleared by the FDA and EMA.”
Key Commercial Product and Pipeline Updates
Olverembatinib (HQP1351) is a novel, next-generation TKI and the first third-generation BCR-ABL1 TKI approved in China for treatment of patients with chronic myeloid leukemia (CML) in chronic-phase (-CP) or CML in accelerated phase (-AP) with T315I mutations, and in CML-CP that is resistant and/or intolerant to first and second-generation TKIs.
Commercial progress
- Revenue from sales of Olverembatinib in China increased
80.6% to US$62.2 million for the year ended December 31, 2025, compared to US$33.0 million for the year ended December 31, 2024. - All approved indications for Olverembatinib have been covered since January 2025 by China’s NRDL, which has bolstered the affordability and accessibility of Olverembatinib.
- The number of hospitals where Olverembatinib is on formulary in Direct-to-Patient, or DTP, pharmacies reached 825 as of December 31, 2025, a
12.4% increase compared to 734 as of December 31, 2024. In particular, the number of hospitals where Olverembatinib is on formulary increased approximately36.5% over the same period to 355 hospitals as of December 31, 2025 from 260 hospitals as of December 31, 2024.
Clinical progress
- Enrollment continues in a FDA and EMA-cleared, global registrational Phase III clinical trial of Olverembatinib in combination with chemotherapy versus investigator choice TKI in combination with chemotherapy in first-line Philadelphia chromosome-positive ALL (Ph+ ALL) patients (POLARIS-1). The Part 1 data from POLARIS-1 was presented at the 67th 2025 American Society of Hematology Annual Meeting and demonstrated an MRD-negative CR rate of
64.2% by the end of the induction therapy and a favorable safety profile to date. - Enrollment continues in a FDA and EMA-cleared, global Phase III registrational clinical trial of Olverembatinib for previously treated CML-CP patients, both with and without T315I mutation (POLARIS-2).
- Enrollment continues in a multinational registrational Phase III clinical trial of Olverembatinib for the treatment of patients with succinate dehydrogenase (SDH)-deficient gastrointestinal stromal tumor (GIST) who have not responded to prior systemic treatment (POLARIS-3).
- Continue to evaluate Olverembatinib in combination with the Bcl-2 inhibitor Lisaftoclax in early phase clinical trials.
Upcoming milestones
- Continue to advance enrollment in the POLARIS-1, POLARIS-2, and POLARIS-3 trials.
Lisaftoclax (APG-2575) is a novel, oral B-cell lymphoma 2 (Bcl-2) inhibitor developed to treat a variety of hematologic malignancies and solid tumors by selectively blocking Bcl-2 to restore the normal apoptosis process in cancer cells.
Commercial progress
- Commercial sales of Lisaftoclax commenced in China on July 25, 2025 as the first batch of prescriptions were filled on July 25, 2025 shortly after receiving approval on July 10, 2025 from China’s National Medical Products Administration (NMPA) for the treatment of adult patients with CLL/SLL who have previously received at least one systemic therapy including BTK inhibitors, which makes Lisaftoclax the first Bcl-2 inhibitor to receive conditional approval and marketing authorization for the treatment of patients with CLL/SLL in China, and the second Bcl-2 inhibitor approved globally.
- Revenue from sales of Lisaftoclax was US
$10.1 million for 2025 for the five-month period from August 2025 to December 2025.
Clinical progress
- Enrollment continues in a FDA and EMA-cleared global Phase III registrational clinical trial of Lisaftoclax in combination with AZA for the treatment of front-line HR-MDS patients (GLORA-4).
- Enrollment continues in a multinational Phase III registrational clinical trial of Lisaftoclax for the treatment of front-line elderly or unfit patients with acute myeloid leukemia (AML) (GLORA-3).
- Enrollment continues in a registrational Phase III clinical trial to evaluate Lisaftoclax in combination with the BTK inhibitor, acalabrutinib, versus immunochemotherapy in treatment-naïve patients with CLL/SLL, to validate a fixed duration of combination regimen as a first-line treatment (GLORA-2).
- Enrollment continues in a FDA and EMA-cleared global Phase III clinical trial of Lisaftoclax in combination with BTK inhibitors in patients with CLL/SLL previously treated with BTK inhibitors (GLORA).
- Enrollment continues Phase Ib/II studies of Lisaftoclax as a single agent or in combination with other therapies for the treatment of patients with AML/MDS, including patients resistant to venetoclax, in China.
- Enrollment continues in the Phase Ib/II clinical trials of Lisaftoclax in combination therapies for the treatment of patients with multiple myeloma (MM) in the United States.
Upcoming milestones
- Plan to initiate clinical studies to confirm Lisaftoclax’s potential to overcome venetoclax resistance in patients who have failed venetoclax treatment.
- Continue to advance enrollment in GLORA, GLORA-2, GLORA-3, GLORA-4 trials.
- Plan to actively advance the inclusion of Lisaftoclax in China’s National Reimbursement Drug List (NRDL) in 2026.
BTK Degrader APG-3288 is the first novel, highly potent and selective BTK degrader developed utilizing Ascentage Pharma’s proprietary proteolysis-targeting chimera (PROTAC) technology platform.
Progress
- Received IND clearance from the FDA and from China’s Center for Drug Evaluation (CDE) in the first quarter of 2026.
Upcoming milestones
- Plan to commence a global, multicenter, open-label Phase I study designed to evaluate the safety, tolerability, pharmacokinetic (PK) profile, and preliminary efficacy of APG-3288 in patients with relapsed/refractory hematologic malignancies.
Full Year 2025 Unaudited Financial Results
Revenue for the year ended December 31, 2025 was US
Selling and distribution expenses for the year ended December 31, 2025 were US
Research and development expenses for the year ended December 31, 2025 were US
Administrative expenses for the year ended December 31, 2025 were US
Finance costs for the year ended December 31, 2025 were US
Other expenses for the year ended December 31, 2025 were US
Loss for the year ended December 31, 2025 was US
Cash and bank balances as of December 31, 2025, were US
Investor Conference Call and Webcast
Ascentage Pharma will be holding investor webcasts to discuss its full year 2025 unaudited annual results.
Ascentage Pharma will host the Chinese (Mandarin) investor event with simultaneous conference call and webcast at 10:00 pm EDT on March 25, 2026 / 10:00 am HKT on March 26, 2025. To access the Chinese language investor event or conference call, please register in advance here.
The English language investor conference call and webcast will be held at 8:00 am EDT / 8:00 pm HKT on March 26, 2026. To access the English language webcast, please register in advance here. The webcast replay for English language conference call and presentation will also be available on the News & Events page of the Ascentage Pharma website.
Statement Regarding Unaudited Financial Information
This press release includes unaudited condensed consolidated financial information as of and for the fiscal year ended December 31, 2025, which has not been audited or reviewed by the Company’s auditors. The unaudited information for the year ended December 31, 2025, is preliminary, based on the information available at this time and subject to changes in connection with the completion of the review of the Company’s financial statements. As such, the Company’s actual results and financial condition as reflected in the financial statements that will be included in the Company’s Annual Report on Form 20-F for the year ended December 31, 2025, may be adjusted or presented differently from the financial information herein and the variations could be material. The unaudited condensed consolidated financial statements for the fiscal year ended December 31, 2025 include the accounts of the Company and its subsidiaries. All periods presented have been accounted for in conformity with IFRS accounting standard as issued by the International Accounting Standards Board and pursuant to the rules and regulations of the U.S. Securities and Exchange Commission (the “SEC”).
Currency and Exchange Rate Information
Unless otherwise indicated, translations from RMB to U.S. dollars for 2025 and 2024 are made at RMB6.9931 to US
About Ascentage Pharma
Ascentage Pharma Group International (NASDAQ: AAPG; HKEX: 6855) (“Ascentage Pharma” or the “Company”) is a global, commercial stage, integrated biopharmaceutical company engaged in the discovery, development and commercialization of novel, differentiated therapies to address unmet medical needs in cancer. The Company has built a rich pipeline of innovative drug products and candidates that include inhibitors targeting key proteins in the apoptotic pathway, such as Bcl-2 and MDM2-p53, next-generation kinase inhibitors, and protein degraders.
The Company’s first approved product, Olverembatinib, is the first novel third-generation BCR-ABL1 inhibitor approved in China for the treatment of patients with CML in chronic phase (CML-CP) with T315I mutations, CML in accelerated phase (CML-AP) with T315I mutations, and CML-CP that is resistant or intolerant to first and second-generation TKIs. It is covered by the China National Reimbursement Drug List (NRDL). Ascentage Pharma is currently conducting an FDA-cleared registrational Phase III trial, called POLARIS-2, of Olverembatinib for CML, as well as registrational Phase III trials for patients with newly diagnosed Ph+ ALL, called POLARIS-1, and SDH-deficient GIST patients, called POLARIS-3.
The Company’s second approved product, Lisaftoclax, is a novel Bcl-2 inhibitor for the treatment of various hematologic malignancies. Lisaftoclax has been approved by China’s National Medical Products Administration (NMPA) for the treatment of adult patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) who have previously received at least one systemic therapy including Bruton’s tyrosine kinase (BTK) inhibitors. The Company is currently conducting four global registrational Phase III trials: the FDA-cleared GLORA study of Lisaftoclax in combination with BTK inhibitors in patients with CLL/SLL previously treated with BTK inhibitors for more than 12 months with suboptimal response; the GLORA-2 study in patients with newly diagnosed CLL/SLL; the GLORA-3 study in newly diagnosed, elderly and unfit patients with AML; and the FDA-cleared GLORA-4 study in patients with newly diagnosed higher risk MDS.
Leveraging its robust R&D capabilities, Ascentage Pharma has built a portfolio of global intellectual property rights and entered into global partnerships and other relationships with numerous leading biotechnology and pharmaceutical companies, such as Takeda, AstraZeneca, Merck, Pfizer, and Innovent, in addition to research and development relationships with leading research institutions, such as Dana-Farber Cancer Institute, Mayo Clinic, National Cancer Institute and the University of Michigan. For more information, visit https://ascentage.com/
Cautionary Note Regarding Forward-Looking Statements
This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. All statements, other than statements of historical facts, contained in this press release may be forward-looking statements, including statements that express Ascentage Pharma’s opinions, expectations, beliefs, plans, objectives, assumptions or projections regarding future events or future results of operations or financial condition. These forward-looking statements are subject to a number of risks and uncertainties as discussed in Ascentage Pharma’s filings with the SEC, including those set forth in the sections titled “Risk factors” and “Cautionary note regarding forward-looking statements” in its Annual Report on Form 20-F for the year ended December 31, 2024, filed with the SEC on April 16, 2025, the sections headed “Forward-looking Statements” and “Risks Factors” in the prospectus of the Company for its Hong Kong initial public offering dated October 16, 2019, and other filings with the SEC and/or The Stock Exchange of Hong Kong Limited where the Company’s ordinary shares are listed it has made or it makes from time to time that may cause actual results, levels of activity, performance or achievements to be materially different from the information expressed or implied by these forward-looking statements. The forward-looking statements contained in this presentation do not constitute profit forecast by the Company’s management.
As a result of these factors, you should not rely on these forward-looking statements as predictions of future events. The forward-looking statements contained in this press release are based on Ascentage Pharma’s current expectations and beliefs concerning future developments and their potential effects and speak only as of the date of such statements. Ascentage Pharma does not undertake any obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.
Contact Information
Investor Relations:
Yuly Chen, Senior Director of Investor Relations
Ascentage Pharma
Yuly.Chen@ascentage.com
+86 512 85557777
Stephanie Carrington
ICR Healthcare
AscentageIR@icrhealthcare.com
+1 (646) 277-1282
Media Relations:
Sean Leous
ICR Healthcare
AscentagePR@icrhealthcare.com
+1 (646) 866-4012
| Ascentage Pharma Group International | ||||||||||||||||
| Condensed Consolidated statements of profit or loss | ||||||||||||||||
| (Amounts in thousands of Renminbi (“RMB”) and U.S. dollar (“US$”), except for number of shares and per share data) | ||||||||||||||||
| For the Year Ended December 31, | ||||||||||||||||
| 2023 | 2024 | 2025 | 2025 | |||||||||||||
| RMB | RMB | RMB | US$ | |||||||||||||
| (Unaudited) | （Unaudited) | |||||||||||||||
| REVENUE | ||||||||||||||||
| Intellectual property | - | 678,415 | - | - | ||||||||||||
| Products | 193,535 | 260,835 | 499,272 | 71,395 | ||||||||||||
| Others | 28,449 | 41,400 | 74,848 | 10,703 | ||||||||||||
| Total revenue | 221,984 | 980,650 | 574,120 | 82,098 | ||||||||||||
| Cost of sales | ||||||||||||||||
| Products | (29,342 | ) | (27,031 | ) | (46,661 | ) | (6,672 | ) | ||||||||
| Others | (1,201 | ) | (2,054 | ) | (2,277 | ) | (326 | ) | ||||||||
| Total cost of sales | (30,543 | ) | (29,085 | ) | (48,938 | ) | (6,998 | ) | ||||||||
| Gross profit | 191,441 | 951,565 | 525,182 | 75,100 | ||||||||||||
| Other income and gains | 59,316 | 57,359 | 103,495 | 14,800 | ||||||||||||
| Selling and distribution expenses | (195,387 | ) | (195,998 | ) | (353,640 | ) | (50,570 | ) | ||||||||
| Administrative expenses | (181,076 | ) | (187,125 | ) | (246,281 | ) | (35,218 | ) | ||||||||
| Research and development expenses | (706,972 | ) | (947,245 | ) | (1,137,448 | ) | (162,653 | ) | ||||||||
| Other expenses | (5,203 | ) | (9,075 | ) | (73,599 | ) | (10,525 | ) | ||||||||
| Finance costs | (96,057 | ) | (64,455 | ) | (54,070 | ) | (7,732 | ) | ||||||||
| Share of profit/(loss) of a joint venture | 1,076 | (281 | ) | 314 | 45 | |||||||||||
| LOSS BEFORE TAX | (932,862 | ) | (395,255 | ) | (1,236,047 | ) | (176,753 | ) | ||||||||
| Income tax credit/(expense) | 7,150 | (10,425 | ) | (6,940 | ) | (992 | ) | |||||||||
| LOSS FOR THE YEAR | (925,712 | ) | (405,680 | ) | (1,242,987 | ) | (177,745 | ) | ||||||||
| Attributable to: | ||||||||||||||||
| Ordinary equity holders of the Company | (925,637 | ) | (405,433 | ) | (1,242,769 | ) | (177,714 | ) | ||||||||
| Non-controlling interests | (75 | ) | (247 | ) | (218 | ) | (31 | ) | ||||||||
| (925,712 | ) | (405,680 | ) | (1,242,987 | ) | (177,745 | ) | |||||||||
| LOSS PER SHARE ATTRIBUTABLE TO ORDINARY EQUITY HOLDERS OF THE COMPANY | ||||||||||||||||
| Basic and Diluted | (3.28 | ) | (1.34 | ) | (3.49 | ) | (0.50 | ) | ||||||||
| Ascentage Pharma Group International | |||||||||||||||
| Condensed Consolidated statements of comprehensive loss | |||||||||||||||
| (Amounts in thousands of Renminbi and U.S. dollar, except for number of shares and per share data) | |||||||||||||||
| For the Year Ended December 31, | |||||||||||||||
| 2023 | 2024 | 2025 | 2025 | ||||||||||||
| RMB | RMB | RMB | US$ | ||||||||||||
| （Unaudited) | （Unaudited) | ||||||||||||||
| LOSS FOR THE YEAR | (925,712 | ) | (405,680 | ) | (1,242,987 | ) | (177,745 | ) | |||||||
| OTHER COMPREHENSIVE INCOME/(LOSS) | |||||||||||||||
| Other comprehensive income that may be reclassified to profit or loss in subsequent periods, net of tax: | |||||||||||||||
| Exchange differences on translation of foreign operations | 20,593 | 2,829 | (41,574 | ) | (5,945 | ) | |||||||||
| Other comprehensive income that will not be reclassified to profit or loss in subsequent periods, net of tax: | - | - | - | - | |||||||||||
| Exchange differences on translation of the Company | 5,666 | 4,120 | (11,441 | ) | (1,636 | ) | |||||||||
| OTHER COMPREHENSIVE INCOME/(LOSS) FOR THE YEAR, NET OF TAX | 26,259 | 6,949 | (53,015 | ) | (7,581 | ) | |||||||||
| TOTAL COMPREHENSIVE LOSS FOR THE YEAR | (899,453 | ) | (398,731 | ) | (1,296,002 | ) | (185,326 | ) | |||||||
| Attributable to: | |||||||||||||||
| Ordinary equity holders of the Company | (899,378 | ) | (398,484 | ) | (1,295,784 | ) | (185,295 | ) | |||||||
| Non-controlling interests | (75 | ) | (247 | ) | (218 | ) | (31 | ) | |||||||
| (899,453 | ) | (398,731 | ) | (1,296,002 | ) | (185,326 | ) | ||||||||
| Ascentage Pharma Group International | |||||||||
| Condensed Consolidated statements of financial position | |||||||||
| (Amounts in thousands of Renminbi and U.S. dollar, except for number of shares and per share data) | |||||||||
| As at December 31, | |||||||||
| 2024 | 2025 | 2025 | |||||||
| RMB | RMB | US$ | |||||||
| （Unaudited) | （Unaudited) | ||||||||
| NON-CURRENT ASSETS | |||||||||
| Property, plant and equipment | 849,450 | 781,235 | 111,715 | ||||||
| Right-of-use assets | 56,109 | 47,827 | 6,839 | ||||||
| Goodwill | 24,694 | 24,694 | 3,531 | ||||||
| Other intangible assets | 75,998 | 65,936 | 9,429 | ||||||
| Investment in a joint venture | 32,717 | 33,030 | 4,723 | ||||||
| Financial assets at fair value through profit or loss (“FVTPL”) | 1,141 | 4,000 | 572 | ||||||
| Deferred tax assets | 44,236 | 31,957 | 4,570 | ||||||
| Other non-current assets | 59,303 | 30,725 | 4,394 | ||||||
| Total non-current assets | 1,143,648 | 1,019,404 | 145,773 | ||||||
| CURRENT ASSETS | |||||||||
| Inventories | 6,597 | 28,618 | 4,092 | ||||||
| Trade receivables, net | 83,143 | 252,938 | 36,170 | ||||||
| Prepayments, other receivables and other assets | 123,211 | 192,532 | 27,532 | ||||||
| Cash and bank balances | 1,261,211 | 2,470,085 | 353,217 | ||||||
| Total current assets | 1,474,162 | 2,944,173 | 421,011 | ||||||
| CURRENT LIABILITIES | |||||||||
| Trade payables | 91,966 | 106,740 | 15,264 | ||||||
| Other payables and accruals | 258,098 | 276,666 | 39,563 | ||||||
| Contract liabilities | 37,485 | 37,485 | 5,360 | ||||||
| Interest-bearing bank and other borrowings | 779,062 | 1,222,481 | 174,812 | ||||||
| Total current liabilities | 1,166,611 | 1,643,372 | 234,999 | ||||||
| NET CURRENT ASSETS | 307,551 | 1,300,801 | 186,012 | ||||||
| TOTAL ASSETS LESS CURRENT LIABILITIES | 1,451,199 | 2,320,205 | 331,785 | ||||||
| Ascentage Pharma Group International | ||||||||||||
| Condensed Consolidated statements of financial position | ||||||||||||
| (Amounts in thousands of Renminbi and U.S. dollar, except for number of shares and per share data) | ||||||||||||
| As at December 31, | ||||||||||||
| 2024 | 2025 | 2025 | ||||||||||
| RMB | RMB | RMB | ||||||||||
| （Unaudited) | （Unaudited) | |||||||||||
| NON-CURRENT LIABILITIES | ||||||||||||
| Contract liabilities | 248,460 | 210,224 | 30,062 | |||||||||
| Interest-bearing bank and other borrowings | 889,435 | 757,238 | 108,284 | |||||||||
| Deferred tax liabilities | 5,368 | - | - | |||||||||
| Deferred income | 27,500 | 6,500 | 929 | |||||||||
| Other non-current liabilities | 6,274 | 12,031 | 1,720 | |||||||||
| Total non-current liabilities | 1,177,037 | 985,993 | 140,995 | |||||||||
| Commitments and contingencies | ||||||||||||
| TOTAL LIABILITIES | 2,343,648 | 2,629,365 | 375,994 | |||||||||
| EQUITY | ||||||||||||
| Equity attributable to ordinary equity holders of the Company | ||||||||||||
| Ordinary shares (par value of US | 214 | 256 | 37 | |||||||||
| Treasury shares | (8 | ) | (2,961 | ) | (423 | ) | ||||||
| Share premium | 6,545,129 | 8,916,853 | 1,275,093 | |||||||||
| Capital and reserves | (384,515 | ) | (397,276 | ) | (56,810 | ) | ||||||
| Exchange fluctuation reserve | (126,071 | ) | (179,086 | ) | (25,609 | ) | ||||||
| Accumulated losses | (5,770,555 | ) | (7,013,324 | ) | (1,002,892 | ) | ||||||
| 264,194 | 1,324,462 | 189,396 | ||||||||||
| Non-controlling interests | 9,968 | 9,750 | 1,394 | |||||||||
| Total equity | 274,162 | 1,334,212 | 190,790 | |||||||||
FAQ
What were Ascentage Pharma (AAPG) full-year 2025 revenues and net loss?
How did Olverembatinib sales perform for AAPG in 2025?
What revenue did Lisaftoclax generate after its July 2025 launch for AAPG?
How much cash did AAPG hold at year-end 2025 and why did it increase?
What were AAPG's key expense changes in 2025 affecting profitability?
What late-stage clinical programs is AAPG advancing in 2026?
