Welcome to our dedicated page for Abbvie news (Ticker: ABBV), a resource for investors and traders seeking the latest updates and insights on Abbvie stock.
AbbVie Inc. (NYSE: ABBV) is a pharmaceutical preparation manufacturing company that regularly issues news on its medicines, research programs, collaborations and manufacturing plans. Company communications emphasize a mission to discover and deliver medicines and solutions in key therapeutic areas such as immunology, oncology, neuroscience and eye care, as well as offerings in its Allergan Aesthetics portfolio.
News about AbbVie often covers clinical and scientific developments, particularly in oncology and blood cancers. The company has reported new data at major medical meetings, including results for investigational agents like etentamig (ABBV‑383) and PVEK, and updates on approved medicines such as EPKINLY (epcoritamab-bysp) and VENCLEXTA (venetoclax). Releases may detail trial outcomes, regulatory milestones, and additional indications under investigation.
Investors and observers can also find corporate and financial updates in AbbVie’s news flow, including announcements of earnings conference calls, participation in healthcare and investor conferences, and guidance-related information that aligns with its SEC filings. The company additionally highlights strategic agreements and collaborations, such as its exclusive licensing agreement with RemeGen for the PD‑1/VEGF bispecific antibody RC148 and its voluntary agreement with the U.S. administration focused on access, affordability and U.S.-based investment.
Another recurring theme in AbbVie’s news is manufacturing and investment activity. The company has announced a definitive agreement to acquire a device manufacturing facility in Tempe, Arizona, to expand drug delivery device manufacturing for immunology and neuroscience medicines, and has referenced multi‑year commitments to U.S. R&D and capital investments. AbbVie also publishes stories on patient- and community-focused initiatives, such as the “Second Winds” film about people living with chronic lymphocytic leukemia. For readers tracking ABBV, this news stream provides insight into the company’s research pipeline, regulatory progress, capital allocation and patient engagement efforts.
AbbVie announced preliminary data from the Phase 2 REFINE study, showing positive early results for navitoclax combined with ruxolitinib in treating JAK inhibitor naïve myelofibrosis (MF) patients. Data revealed a 63% spleen volume reduction of ≥35% at week 24. Additionally, 41% of evaluable patients reported a ≥50% reduction in symptom scores. No new safety signals were identified, though 97% of patients reported adverse events, with thrombocytopenia being the most common. These findings could support further exploration of navitoclax as a treatment to modify disease progression.
AbbVie announced five-year follow-up results from the Phase 3 CLL14 trial, revealing that over 60% of patients with untreated chronic lymphocytic leukemia (CLL) who received a one-year treatment of venetoclax plus obinutuzumab maintained longer progression-free survival (PFS) compared to those treated with chlorambucil plus obinutuzumab. The median PFS was not reached for the venetoclax group versus 36.4 months for the chlorambucil group (p0.0001). Moreover, 18.1% of patients treated with venetoclax showed undetectable minimal residual disease after four years, demonstrating the regimen's effectiveness in CLL treatment.
AbbVie announced it will showcase data from its migraine portfolio at the 2022 AHS Annual Scientific Meeting in Denver, June 9-12. The highlights include findings from the Phase 3 PROGRESS trial for atogepant (QULIPTA) in preventing chronic migraine. This research may support a supplemental New Drug Application with the FDA to expand atogepant’s indication. AbbVie will also present data on ubrogepant (UBRELVY) and onabotulinumtoxinA (BOTOX), enhancing its commitment to treating migraine sufferers. A total of 29 abstracts will provide insights into ongoing research in migraine therapies.
AbbVie announced positive outcomes from the Phase 3 SELECT-AXIS 2 trials of upadacitinib (RINVOQ) aimed at treating non-radiographic axial spondyloarthritis (nr-axSpA) and ankylosing spondylitis (AS) in patients with inadequate responses to existing therapies. Both studies met the primary endpoint, achieving the ASAS40 response at week 14—45% for nr-axSpA compared to 23% placebo, and 45% for AS compared to 18% placebo. Safety profiles remained consistent with previous studies, with no new risks identified. Regulatory applications to the FDA and EMA for nr-axSpA are ongoing.
AbbVie announced that The Lancet published results from three pivotal Phase 3 trials of upadacitinib (RINVOQ) for treating moderately to severely active ulcerative colitis. The U-ACHIEVE (induction), U-ACCOMPLISH, and U-ACHIEVE (maintenance) studies demonstrated the efficacy and safety of upadacitinib in patients with inadequate responses to prior therapies. The studies focused on clinical remission and endoscopic improvement over 8 weeks and 52 weeks. While RINVOQ is not yet approved in the EU, it is currently under review by global health authorities.
AbbVie (NYSE: ABBV) announced results from three pivotal Phase 3 clinical trials published in The Lancet, focusing on risankizumab (SKYRIZI) for treating moderately to severely active Crohn's disease. The ADVANCE and MOTIVATE studies evaluated induction therapy efficacy, while the FORTIFY study assessed maintenance therapy. Results showed significant improvements in clinical remission and endoscopic response. However, risankizumab's approval for Crohn's disease is pending, as safety and efficacy are under regulatory review.
Genmab (Nasdaq: GMAB) announced the acceptance of multiple abstracts for presentation at the 2022 ASCO Annual Meeting, showcasing investigational medicines from its pipeline. Key highlights include data from the phase 1b/2 EPCORE™ NHL-2 trial evaluating epcoritamab (DuoBody-CD3xCD20) in B-cell non-Hodgkin lymphoma and an oral presentation of tisotumab vedotin in recurrent or metastatic cervical cancer. The findings reinforce Genmab's commitment to delivering innovative therapies, with partnerships alongside AbbVie (ABBV) and Seagen (SGEN).
AbbVie (NYSE: ABBV) will participate in the Bernstein 38th Annual Strategic Decisions Conference on June 1, 2022, at 10:00 a.m. Central Time. Richard A. Gonzalez, chairman and CEO, will present. A live audio webcast will be available on AbbVie's Investor Relations website, with an archived version accessible later the same day.
AbbVie focuses on discovering and delivering innovative medicines across various therapeutic areas, including immunology, oncology, and neurology. For more information, visit www.abbvie.com.
AbbVie (NYSE: ABBV) announced significant data presentations at the EULAR 2022 Congress, highlighting the efficacy and safety of its treatments, including upadacitinib (RINVOQ) and risankizumab (SKYRIZI). Key studies include SELECT-AXIS 2, showcasing RINVOQ in axial spondyloarthritis, and SELECT-PsA 1 & 2, demonstrating its impact on psoriatic arthritis patients. The congress will feature 25 posters, 3 oral presentations, and insights from various clinical trials, underscoring AbbVie's commitment to advancing rheumatic disease management.
AbbVie announced positive results from Study 3111-301-001, where cariprazine (VRAYLAR) demonstrated statistically significant improvement in major depressive disorder (MDD) patients inadequately responsive to current antidepressants. The study achieved its primary endpoint based on the Montgomery-Åsberg Depression Rating Scale (MADRS), with p-value 0.0050. The FDA is reviewing AbbVie's supplemental New Drug Application (sNDA) for cariprazine's expanded use in MDD, with a decision expected by year-end. The safety profile remained consistent with previous studies, with no deaths reported and manageable adverse events.