Welcome to our dedicated page for Arbutus Biopharm news (Ticker: ABUS), a resource for investors and traders seeking the latest updates and insights on Arbutus Biopharm stock.
Arbutus Biopharma Corp (NASDAQ: ABUS) generates news primarily through clinical trial updates, scientific conference presentations, and corporate milestones in its pursuit of hepatitis B virus (HBV) cure therapies. As a clinical-stage biopharmaceutical company, Arbutus regularly reports on the progress of its drug candidates through the development pipeline.
News coverage for Arbutus typically includes clinical trial data readouts for imdusiran and AB-101, the company's lead HBV drug candidates. Investors and researchers monitoring HBV therapeutic development follow these updates closely, as trial results shape understanding of whether combination approaches can achieve functional cure. Conference presentations at major hepatology meetings provide additional scientific detail beyond press releases.
Quarterly financial reports reveal the company's cash position and operating expenses, critical metrics for clinical-stage biotechs that rely on financing rather than product revenue. These reports often coincide with pipeline updates and forward-looking guidance on clinical timelines. Partnership announcements and licensing deals related to Arbutus's lipid nanoparticle (LNP) technology platform also generate coverage.
Regulatory interactions, including FDA communications and clinical trial design decisions, inform expectations about development pathways. Board and leadership changes affect corporate strategy and investor sentiment. For those tracking the competitive HBV cure landscape, Arbutus news provides insight into one focused player's progress toward transforming chronic infection treatment.
Bookmark this page to follow Arbutus Biopharma's clinical development progress and corporate updates as the company advances its hepatitis B cure programs.
Arbutus Biopharma Corporation (Nasdaq: ABUS) has received FDA authorization for its Investigational New Drug application to initiate a Phase 2a clinical trial for AB-729, targeting chronic hepatitis B virus (CHB) infection. The trial will evaluate the safety and efficacy of AB-729 in combination with nucleos(t)ide analog therapy and short courses of Peg-IFNα-2a. The randomized trial aims to enroll 40 subjects and is expected to start this quarter, with the potential to establish AB-729 as a cornerstone therapy for CHB.
Arbutus Biopharma Corporation (Nasdaq: ABUS) and Vaccitech plc (Nasdaq: VACC) announced a clinical trial collaboration to assess a combination therapy for chronic hepatitis B (CHB) patients receiving nucleos(t)ide reverse transcriptase inhibitors (NrtIs). The Phase 2a trial will evaluate the safety and efficacy of Arbutus’s AB-729 and Vaccitech’s VTP-300 in a double-blind study. Enrollment is projected for 40 subjects, with initiation expected in the second half of 2021. Positive results may lead to a larger Phase 2b trial.
Arbutus Biopharma (Nasdaq: ABUS) and Antios Therapeutics have signed a clinical collaboration to evaluate a triple therapy for chronic hepatitis B involving Arbutus' AB-729 and Antios' ATI-2173, along with Viread. This Phase 2a trial will assess safety, pharmacokinetics, immunogenicity, and antiviral activity in patients. The trial is slated to start in H2 2021, with Antios covering the costs and Arbutus supplying AB-729. Early results for ATI-2173 show promise as a potential backbone in curative regimens, while AB-729 has demonstrated positive safety and efficacy in prior studies.
Arbutus Biopharma has announced promising results for its HBV treatment candidate, AB-729, which achieved a mean HBsAg decline of -1.87 log10 IU/mL after 44 weeks. In a clinical trial, 75% of subjects receiving AB-729 at 60 mg every 4 weeks had HBsAg levels below 100 IU/mL. Additionally, AB-729 demonstrated a favorable safety profile and showed potential for increased immune responses. The company is set to initiate Phase 2a trials later this year. The efficacy and safety data support AB-729 as a leading candidate in chronic hepatitis B treatment.
Arbutus Biopharma Corporation (Nasdaq: ABUS) announced acceptance of five abstracts for the International Liver Congress 2021, focusing on chronic hepatitis B virus (HBV) treatments. Key presentations include a late-breaker on the GalNAc-siRNA AB-729, demonstrating HBsAg suppression, and the preclinical profile of the HBV capsid inhibitor AB-836. A conference call is scheduled for June 28, 2021, to discuss these findings. Hepatitis B continues to pose significant health challenges globally, affecting over 250 million people.
Arbutus Biopharma Corporation (Nasdaq: ABUS), focused on chronic hepatitis B virus (HBV) and coronavirus therapies, announced participation in two virtual investor conferences. The first is the Jefferies Virtual Healthcare Conference on June 2, 2021, featuring a fireside chat at 9:00 am ET. Presenters include CEO William Collier and other executives. The second is the JMP Securities Life Sciences Conference on June 17, 2021, at 11:00 am ET, also featuring a fireside chat. Links to webcasts are available on their website.
Arbutus Biopharma Corporation (Nasdaq: ABUS) reported its Q1 2021 results, showcasing advancements in its HBV pipeline, particularly with AB-729 and AB-836. AB-729 has shown significant declines in hepatitis B surface antigen levels with promising safety profiles. The company commenced a Phase 2 clinical trial for a combination regimen involving AB-729 and other treatments for chronic HBV. Financially, Arbutus ended Q1 with $132 million in cash but recorded a net loss of $19.6 million. The firm anticipates significant data releases and trial advancements in the coming quarters.
Arbutus Biopharma Corporation (Nasdaq: ABUS) has announced its first quarter 2021 financial results and corporate update scheduled for May 5, 2021. Key details include the release of the financial results at 7:30 a.m. ET followed by a conference call/webcast at 8:45 a.m. ET. The domestic dial-in number for the call is (866) 393-1607, and international callers can reach (914) 495-8556 with conference ID 4445858. Arbutus focuses on developing treatments for chronic hepatitis B and coronaviruses.
Arbutus Biopharma (NASDAQ: ABUS), in collaboration with X-Chem and Proteros, has announced a new agreement to discover oral inhibitors targeting the SARS-CoV-2 nsp5 main protease. This partnership aims to speed up the development of treatments for COVID-19 and future coronaviruses. The collaboration leverages Arbutus's antiviral expertise, X-Chem's DNA-encoded library technology, and Proteros' structural biology capabilities. The financial terms of the agreement remain undisclosed, and the goal is to identify unique antiviral therapies that can lead to oral treatments for coronavirus-related diseases.
Arbutus Biopharma Corporation (Nasdaq: ABUS) has received regulatory approval to start a Phase 1a/1b clinical trial for AB-836, its oral capsid inhibitor targeting chronic hepatitis B virus (HBV) infection. The trial initiation is a significant milestone toward potential combinations with AB-729. Pre-clinical studies suggest that AB-836 may offer improved efficacy and safety compared to earlier capsid inhibitors. This candidate has demonstrated activity against resistant HBV variants, highlighting its potential in a large patient population suffering from chronic HBV, estimated at over 250 million globally.
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