Welcome to our dedicated page for Arbutus Biopharm news (Ticker: ABUS), a resource for investors and traders seeking the latest updates and insights on Arbutus Biopharm stock.
Arbutus Biopharma Corporation (Nasdaq: ABUS) is a clinical-stage biopharmaceutical company focused on infectious disease, with a particular emphasis on chronic hepatitis B virus (cHBV) infection. The ABUS news feed highlights company announcements on clinical data, corporate strategy and intellectual property developments that shape the outlook for its pipeline and technology.
Investors and observers following ABUS news can find regular updates on imdusiran (AB-729), Arbutus’ RNAi therapeutic designed to reduce hepatitis B viral proteins and antigens including HBsAg. News items include results from Phase 1 and Phase 2a trials, such as reports of patients achieving what the company describes as functional cure, analyses of HBsAg and HBV DNA reductions, and presentations at major liver disease conferences including the European Association for the Study of the Liver (EASL) Congress and the American Association for the Study of Liver Diseases (AASLD) – The Liver Meeting.
The ABUS news stream also covers developments related to AB-101, the company’s oral PD-L1 inhibitor candidate. Releases describe safety, tolerability and pharmacodynamic findings from the ongoing Phase 1a/1b trial in healthy volunteers and cHBV patients, including data on PD-L1 receptor occupancy and the absence of AB-101-related serious adverse events reported to date.
Another recurring theme in Arbutus news is its LNP intellectual property. Joint announcements with Genevant Sciences and company updates detail U.S. and international patent infringement actions against Moderna and Pfizer/BioNTech concerning the use of LNP technology in COVID-19 vaccines. Corporate news also includes board and executive changes, restructuring actions, and strategic decisions such as reacquiring Greater China rights to imdusiran and forming a Scientific Advisory Board of cHBV experts.
For those tracking ABUS stock and the company’s progress in hepatitis B and LNP technology, this news page provides a centralized view of clinical milestones, litigation updates and corporate developments as disclosed by Arbutus in its press releases.
Arbutus Biopharma Corporation (Nasdaq: ABUS) reported their second quarter 2022 financial results, showing a strong financial position with cash and equivalents of $200.6 million, ensuring a runway into Q2 2024. Revenue surged to $14.2 million, up from $2.3 million a year earlier, primarily due to a license agreement with Qilu Pharmaceutical. Clinical advancements were made in their hepatitis B and pan-coronavirus programs, including promising data from their lead therapies AB-729 and AB-836. The company remains focused on its pipeline and upcoming trials.
Arbutus Biopharma Corporation (Nasdaq: ABUS) announced its second quarter 2022 financial results and corporate update on August 4, 2022. The company will release its Q2/2022 press release at 7:30 a.m. ET, followed by a conference call/webcast at 8:45 a.m. ET. Investors can access the live webcast through the Investors section of Arbutus' website. The company focuses on innovative therapeutics for viral diseases, including Hepatitis B and coronaviruses, and is advancing its lead compound, AB-729, in multiple phase 2 clinical trials.
Arbutus Biopharma Corporation (Nasdaq: ABUS) announced the continuation of its Phase 2a clinical trial evaluating AB-729, an RNAi therapeutic, in combination with Assembly Biosciences' discontinued vebicorvir and nucleos(t)ide analogue for chronic HBV infection. Despite Assembly's decision to halt VBR development, Arbutus intends to continue patient dosing, with preliminary data expected in the second half of 2022. AB-729 is positioned as a cornerstone in potential HBV treatments, aiming for significant reductions in viral biomarkers.
Arbutus Biopharma (Nasdaq: ABUS) presented promising data at the EASL International Liver Congress regarding its pipeline for chronic hepatitis B (cHBV). Key findings include AB-729, which demonstrated significant HBsAg declines in 50% of patients, with sustained virologic control after treatment cessation. AB-836 showed mean declines in HBV DNA, but safety concerns arose in a subset. The company plans further trials for both AB-836 and AB-101, an oral PD-L1 inhibitor, indicating a strong commitment to advancing therapies for cHBV.
Arbutus Biopharma Corporation (Nasdaq: ABUS) announced that seven abstracts have been accepted for poster presentations at the EASL International Liver Congress™ 2022, scheduled for June 22-26, 2022, in London. The presentations will focus on Viral Hepatitis B/D therapy and highlight new data from trials involving AB-729 and AB-836. A conference call is set for June 27, 2022, at 8:00 am ET to discuss these findings. Key studies presented include significant progress in HBsAg suppression and long-term antiviral effects.
Arbutus Biopharma Corporation (Nasdaq: ABUS) and Vaccitech plc (Nasdaq: VACC) announced the dosing of the first patient in a Phase 2a clinical trial evaluating the RNAi therapeutic AB-729 in combination with VTP-300 and nucleos(t)ide reverse transcriptase inhibitor therapy, targeting chronic HBV infection. The trial will enroll 40 patients to assess safety and antiviral activity. AB-729 aims to reduce HBV viral proteins, potentially reawakening the immune system. This collaboration seeks to improve HBsAg reduction and T-cell responses.
Arbutus Biopharma Corporation (Nasdaq: ABUS) announced its participation in two upcoming investor conferences in New York. The Jefferies Healthcare Conference will take place from June 8-10, 2022, featuring a fireside chat with key executives on June 9 at 3:00 pm ET. The JMP Securities Life Sciences Conference is scheduled for June 15-16, 2022, with a fireside chat on June 15 at 9:00 am ET. Live webcasts can be accessed via the company's website. Arbutus specializes in developing therapeutics for viral diseases, including Hepatitis B and coronaviruses.
Arbutus Biopharma Corporation (Nasdaq: ABUS) announced that its abstract on a preclinical oncology study of an oral PD-L1 inhibitor will be published at the ASCO Annual Meeting on June 3-7, 2022. The abstract titled "Pre-clinical anti-tumor activity of small-molecule oral PD-L1 checkpoint inhibitors" focuses on the compound's potential to stimulate the immune system. This publication may enhance Arbutus' visibility in oncology, complementing its efforts in viral diseases like Hepatitis B and SARS-CoV-2.
Arbutus Biopharma Corporation (Nasdaq: ABUS) announced that its President and CEO, William Collier, will present at the H.C. Wainwright Global Investment Conference on May 24, 2022, at 11:30 am ET in Miami, FL. The conference will focus on Arbutus' innovative therapeutics targeting viral diseases, especially its lead compound AB-729, aimed at treating chronic Hepatitis B. A live webcast can be accessed via Arbutus' website, with an archived replay available afterward.
Arbutus Biopharma Corporation (Nasdaq: ABUS) reported first quarter 2022 financial results, highlighting significant advancements in its chronic hepatitis B virus (cHBV) and pan-coronavirus programs. The company achieved revenue of $12.6 million, a substantial increase from $2.1 million in Q1 2021, primarily due to a $9.6 million license agreement with Qilu Pharmaceutical. Although the net loss decreased to $15.8 million from $19.6 million year-over-year, research and development expenses rose to $18.5 million. Arbutus maintains a cash runway projected into the second quarter of 2024.