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Acrivon Therapeutics to Present at the TD Cowen 46th Annual Health Care Conference

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Acrivon Therapeutics (Nasdaq: ACRV) will present at the TD Cowen 46th Annual Health Care Conference in Boston on Monday, March 2, 2026 at 1:50 p.m. ET.

Peter Blume-Jensen, M.D., Ph.D., president and CEO, will appear in a fireside chat. A live and archived webcast will be available via the company's Events & Presentations investor webpage.

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Market Context

This announcement highlights Acrivon’s participation in the TD Cowen health care conference, extendi...
Analysis

This announcement highlights Acrivon’s participation in the TD Cowen health care conference, extending visibility efforts after recent ACR-368 Phase 2b data and CLIA lab certification. Investors may focus on how management frames clinical progress, cash of about $119M, and plans for larger trials. Recent history shows mixed price responses to positive news, so monitoring subsequent clinical disclosures, insider activity, and execution against stated timelines remains important.

Key Figures

Overall ORR: 39% ORR ≤2 prior lines: 44% Confirmed ORR BM+ serous: 67% +5 more
8 metrics
Overall ORR 39% ACR-368 Phase 2b endometrial cancer data
ORR ≤2 prior lines 44% ACR-368 Phase 2b subjects with ≤2 prior therapies
Confirmed ORR BM+ serous 67% BM+ serous endometrial cancer (N=12)
cORR serous subjects 52% All serous endometrial cancer subjects (N=23)
Arm 3 enrollment target 90 subjects ACR-368 + ultra-low dose gemcitabine serous cohort
BM+ serous sample size 12 patients ACR-368 Phase 2b BM+ serous endometrial subset
Serous sample size 23 patients All serous endometrial subjects in ACR-368 Phase 2b
Cash & investments $119M As of 12/31/2025, funding into Q2 2027

Historical Context

5 past events · Latest: Feb 18 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Feb 18 CLIA lab certification Positive -0.6% Completion and CLIA certification of internal clinical laboratory in Watertown.
Jan 23 Conference presentation Positive +1.0% Late-breaking oral presentation of interim ACR-368 Phase 2b data at ESGO.
Jan 08 Clinical data update Positive -34.6% Positive ACR-368 Phase 2b data, ACR-2316 initial data, and AP3 pipeline update.
Jan 06 Upcoming data webcast Positive +31.4% Announcement of planned webcast for ACR-368 and ACR-2316 clinical updates.
Dec 17 Webcast preview Positive -4.5% Advance notice of January 2026 clinical and pipeline update webcast.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent ACRV news has often seen negative or muted price reactions even on seemingly positive clinical or strategic updates, with more divergences than alignments.

Recent Company History

Over the last few months, Acrivon reported several clinically and strategically positive updates, including strong ACR-368 Phase 2b efficacy data and CLIA certification of its internal lab. Yet reactions were mixed: a data preview on Jan 6, 2026 coincided with a +31.44% move, while detailed positive data on Jan 8, 2026 saw a -34.58% reaction. Today’s TD Cowen conference participation fits into a cadence of ongoing visibility events following these clinical milestones.

Key Terms

phosphoproteomics
1 terms
phosphoproteomics medical
"precision medicines utilizing its proprietary Generative Phosphoproteomics AP3..."
Phosphoproteomics is the large-scale study of proteins that have phosphate tags attached, which act like on/off switches controlling cell behavior. Investors care because mapping these switches helps scientists identify disease mechanisms, drug targets, and biomarkers that can speed up development, improve patient selection, and increase the commercial potential of therapies or diagnostic tests—similar to inspecting a circuit board to find the best place to fix or upgrade a device.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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WATERTOWN, Mass., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Acrivon Therapeutics, Inc. (“Acrivon” or “Acrivon Therapeutics”) (Nasdaq: ACRV), a clinical stage biotechnology company discovering and developing precision medicines utilizing its proprietary Generative Phosphoproteomics AP3 (Acrivon Predictive Precision Proteomics) platform deployed for rational drug design and predictive clinical development, today announced the company’s president and chief executive officer, Peter Blume-Jensen, M.D., Ph.D., will participate in a fireside chat on Monday, March 2, 2026, at 1:50 p.m. ET at the TD Cowen 46th Annual Health Care Conference in Boston.

The live and archived webcast of this event can be accessed through a link on the Events & Presentations page within the investor section of the company’s website at https://ir.acrivon.com/news-events/events-presentations.

About Acrivon Therapeutics
Acrivon is a clinical stage biopharmaceutical company discovering and developing precision medicines utilizing its proprietary Generative Phosphoproteomics AP3 platform. The platform allows the company to interpret and quantify compound specific, drug-regulated pathway activity levels inside the intact cell in an unbiased manner, yielding terabytes of proprietary data and delivering rapid, actionable insights. The Generative Phosphoproteomics AP3 platform is comprised of a growing suite of powerful, internally-developed tools, including the AP3 Data Portal, converting multimodal data into structured data for generative AI analyses, the AP3 Kinase Substrate Relationship Predictor and the AP3 Interactome. These distinctive capabilities enable the company to go beyond the limitations of traditional drug discovery, as well as current AI-based target-centric drug discovery, and rapidly design highly differentiated compounds with desirable pathway effects through intracellular protein network analyses and advance these agents into the clinic for streamlined development.

Acrivon is currently advancing its lead program, ACR-368 (also known as prexasertib), a selective small molecule inhibitor targeting CHK1 and CHK2 in a potentially registrational Phase 2 trial for endometrial cancer. The company has received Fast Track designation from the Food and Drug Administration, or FDA, for the investigation of ACR-368 as a monotherapy based on OncoSignature-predicted sensitivity in patients with endometrial cancer. The FDA has granted a Breakthrough Device designation for the ACR-368 OncoSignature assay for the identification of patients with endometrial cancer who may benefit from ACR-368 treatment.

In addition to ACR-368, Acrivon is also leveraging its proprietary Generative Phosphoproteomics AP3 platform for developing its co-crystallography-driven, internally discovered pipeline programs. These include ACR-2316, the company’s second clinical stage asset, a novel, potent, selective WEE1/PKMYT1 inhibitor designed for superior single-agent activity through strong activation of not only CDK1 and CDK2, but also of PLK1 to drive pro-apoptotic cell death, as observed in preclinical studies against benchmark inhibitors. The Phase 1 trial of ACR-2316 is advancing, with weekly dosing regimens established. Initial data has shown a favorable tolerability profile limited to transient, mechanism-based hematological adverse events, predominantly neutropenia and initial clinical activity across AP3-selected solid tumor types, including PRs in endometrial cancer, as well as SCLC and sqNSCLC, two tumor types which have not shown sensitivity to other clinical WEE1 or PKMYT1 inhibitors currently in development. In addition, the company is advancing ACR-6840, an internally discovered development candidate targeting CDK11.

Forward-Looking Statements
This press release includes certain disclosures that contain “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 about us and our industry that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations or financial condition, business strategy and plans and objectives of management for future operations, are forward-looking statements. In some cases, you can identify forward-looking statements because they contain words such as “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” or “would” or the negative of these words or other similar terms or expressions. Forward-looking statements are based on Acrivon’s current expectations and are subject to inherent uncertainties, risks and assumptions that are difficult to predict. Factors that could cause actual results to differ include, but are not limited to, risks and uncertainties that are described more fully in the section titled “Risk Factors” in our reports filed with the Securities and Exchange Commission. Forward-looking statements contained in this press release are made as of this date, and Acrivon undertakes no duty to update such information except as required under applicable law.

Investor and Media Contacts:
Adam D. Levy, Ph.D., M.B.A.
alevy@acrivon.com

Alexandra Santos
asantos@wheelhouselsa.com


FAQ

When will Acrivon Therapeutics (ACRV) present at the TD Cowen 46th Annual Health Care Conference?

Acrivon will present on Monday, March 2, 2026 at 1:50 p.m. ET. According to Acrivon, Peter Blume-Jensen, M.D., Ph.D., will participate in a fireside chat at that scheduled time.

Who from Acrivon (ACRV) will speak at the TD Cowen conference on March 2, 2026?

Peter Blume-Jensen, M.D., Ph.D., president and CEO, will participate in a fireside chat. According to Acrivon, he will represent the company in the March 2, 2026 session.

How can investors watch Acrivon Therapeutics (ACRV) presentation at TD Cowen on March 2, 2026?

Investors can watch a live webcast and access an archived replay on the company's investor Events & Presentations page. According to Acrivon, the link will be posted on its investor website.

Will the Acrivon (ACRV) TD Cowen presentation be archived for later viewing?

Yes, the presentation will be archived for later viewing on the company's investor Events & Presentations page. According to Acrivon, both live and archived webcasts will be available online.

What topics will Acrivon (ACRV) likely cover in the March 2, 2026 fireside chat?

The fireside chat will cover company developments and the AP3 platform used for drug discovery. According to Acrivon, the discussion will reflect its precision proteomics approach and development priorities.