Adc Therapeutics Sa Stock Price, News & Analysis

ADC Therapeutics (NYSE: ADCT) announces CEO Chris Martin's participation in a fireside chat at the 2021 Cantor Virtual Global Healthcare Conference on Thursday, September 30, at 9:20 a.m. ET. A live webcast will be accessible on the company's Investors page, with a replay available for 30 days. ADC Therapeutics focuses on developing targeted antibody drug conjugates (ADCs) for cancer treatment, with its CD19-directed ADC ZYNLONTA® approved by the FDA for relapsed diffuse large B-cell lymphoma. The company also has other ADCs in clinical and preclinical development.

ADC Therapeutics has received Orphan Drug Designation from the European Commission for ZYNLONTA®, a CD19-targeted antibody drug conjugate (ADC) aimed at treating diffuse large B-cell lymphoma (DLBCL). This designation highlights the significant unmet medical need within the EU for DLBCL patients. Should ZYNLONTA be approved, it will enjoy ten years of marketing exclusivity and various incentives. The FDA-approved ZYNLONTA has shown promising clinical trial results, with an overall response rate of 48.3% for patients after two or more lines of therapy.

ADC Therapeutics (NYSE: ADCT) has announced that Chief Medical Officer Joseph Camardo and Chief Commercial Officer Jennifer Herron will participate in a fireside chat at Morgan Stanley’s 19th Annual Global Healthcare Conference on September 14 at 8:45 a.m. ET. Investors can access a live webcast and replay through the company's website for 30 days. ADC Therapeutics focuses on innovative antibody drug conjugates (ADCs) aimed at treating cancer, including their FDA-approved ZYNLONTA® for specific lymphoma treatments.

ADC Therapeutics (NYSE: ADCT) announced the departure of Chief Medical Officer Jay Feingold, who is leaving to pursue a new opportunity. He played a crucial role in the growth of the company, particularly in the development of ZYNLONTA, its first commercial therapy. Joseph Camardo has been appointed as the new Chief Medical Officer, bringing extensive experience from previous roles at Celgene and Wyeth. Camardo's leadership is expected to ensure continuity in clinical development as the company advances its proprietary antibody drug conjugates for treating cancer.

ADC Therapeutics (ADCT) announced a $325 million royalty purchase agreement with HealthCare Royalty Partners. This deal includes $225 million upon closing and up to $100 million in future milestone payments for ZYNLONTA™ and Cami. ADCT will pay a 7% royalty on net sales from ZYNLONTA and Cami, with a cap of 2.25x to 2.50x the amount received. Proceeds will support further development and commercialization of these therapies, enhancing ADCT's financial position.

ADC Therapeutics (NYSE: ADCT) reported its Q2 2021 financial results, highlighting accelerated FDA approval for ZYNLONTA™ and net sales of $3.8 million since the April launch. R&D expenses rose to $39.5 million due to commercial preparations, while sales and marketing expenses increased to $15.2 million. The net loss decreased to $72.6 million, or $0.95 per share, compared to $126.6 million in Q2 2020. Positive trial results and upcoming milestones for ZYNLONTA were noted, along with ongoing efforts for geographic expansion and further clinical studies.

ADC Therapeutics (NYSE: ADCT) is set to host a conference call on August 3, 2021, at 8:30 a.m. EDT. The purpose is to discuss Q2 2021 financial results and share business updates. Investors can join via telephone or through a live webcast available on the company's website. ADC Therapeutics is focused on developing novel antibody drug conjugates for cancer treatment, with ZYNLONTA™ approved for certain lymphomas and ongoing trials for other therapies including Cami for Hodgkin lymphoma.

ADC Therapeutics (NYSE: ADCT) reported updated interim results from its ongoing Phase 2 trial of camidanlumab tesirine (Cami) in relapsed or refractory Hodgkin lymphoma at the 16th Annual ICML. The trial, aimed at supporting a Biologics License Application, includes 117 patients and shows an overall response rate (ORR) of 66.3% with 27.7% achieving complete responses. The median duration of response has not been reached. No new safety signals emerged, and treatment-related adverse events were consistent with prior phases. Cami targets heavily pre-treated patients with limited options.

ADC Therapeutics (NYSE:ADCT) announced the presentation of updated results from four clinical trials of ZYNLONTA™ (loncastuximab tesirine-lpyl) at the 16th Annual International Conference on Malignant Lymphoma (ICML). Key findings from the LOTIS-2 trial showed an overall response rate (ORR) of 48.3% and a median duration of response (mDoR) of 13.4 months in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The LOTIS-3 trial results reflected a 62.2% ORR when ZYNLONTA was combined with ibrutinib, with manageable toxicity. The company anticipates continued progress in ongoing clinical trials.